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At Cincinnati Children's, genomics is changing the landscape of research and treatment. The Spring 2016 edition of Research Horizons explores the far-reaching impacts of genomic advancement through our medical center and community.
A novel mouse model of a highly lethal form of acute myeloid leukemia (AML) has been developed at Cincinnati Children’s and offers scientists an important tool to better understand this disease and research new therapeutic targets. “This model is rapid, fully penetrant, and completely spontaneous. We hope that it will open the way for other researchers to join us in attacking this particularly lethal AML subtype,” says H. Leighton Grimes, PhD, senior author and professor in the Division of Immunobiology. Results are reported in Cancer Discovery.
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