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The Comprehensive Neuromuscular Center at Cincinnati Children's is home to specialists with a variety of backgrounds and areas of focus. As a team, this diversity makes us better prepared to care for your child's unique needs.
Brenda Wong, MD, MBBS Professor of Clinical Pediatrics and Neurology, Director of Comprehensive Neuromuscular Center
Professor of Clinical Pediatrics and Neurology, Director of Comprehensive Neuromuscular Center
Associate Professor, UC Department of Pediatrics
After medical school, Brenda Wong, MD, received training in General Pediatrics and worked as a pediatrician for a few years before doing her three-year Child Neurology fellowship at Children's Hospital Medical Center, Cincinnati.
Dr. Wong also received training in Pediatric Neuromuscular Disorders at Hammersmith Hospital, London with Dr. Victor Dubowitz and Dr. Francesco Muntoni. Dr. Wong's training in EMGs was accomplished with Dr. John Quinlan at Department of Neurology, University of Cincinnati.
Post fellowship training, Dr. Wong was practicing child neurology in private practice prior to joining Children's Hospital Medical Center of Cincinnati in 1999.
Besides general neurology patients, Dr. Wong sees patients with neuromuscular disorders in the Neuromuscular Clinic and provide diagnostic services like EMGs and evaluation for muscle biopsies. Comprehensive management is supported by the Department of Rehabilitative Medicine, Pulmonary Medicine, Pediatric Orthopedics and the Muscular Dystrophy Association.
MD: University of Singapore, 1980.
Residency: University Department of Pediatrics, Singapore, 1981, 1984-85, Royal Hospital for Sick Children, Edinburgh 1985-88.
Fellowship: Child Neurology, Children's Hospital Medical Center, Cincinnati, OH, 1994-97; Neuromuscular Disorders, Hammersmith Hospital, London, 1997.
Certification: Child Neurology, 1998.
Miles MV, Putnam PE, Miles L, Tang PH, DeGrauw AJ, Wong BL, Horn PS, Foote HL, Rothenberg ME. Acquired coenzyme Q10 deficiency in children with recurrent food intolerance and allergies. Mitochondrion. 2011 Jan;11(1):127-35.
Kim HK, Laor T, Horn PS, Racadio JM, Wong B, Dardzinski BJ. T2 mapping in Duchenne muscular dystrophy: distribution of disease activity and correlation with clinical assessments. Radiology. 2010 Jun;255(3):899-908. Kim HK, Laor T, Horn PS, Wong B. Quantitative assessment of the T2 relaxation time of the gluteus muscles in children with Duchenne muscular dystrophy: a comparative study before and after steroid treatment. Korean J Radiol. 2010 May-Jun;11(3):304-11. Yang Z, Funke BH, Cripe LH, Vick GW 3rd, Mancini-Dinardo D, Peña LS, Kanter RJ, Wong B, Westerfield BH, Varela JJ, Fan Y, Towbin JA, Vatta M. LAMP2 microdeletions in patients with Danon disease. Circ Cardiovasc Genet. 2010 Apr;3(2):129-37. Henderson RC, Berglund LM, May R, Zemel BS, Grossberg RI, Johnson J, Plotkin H, Stevenson RD, Szalay E, Wong B, Kecskemethy HH, Harcke HT. The relationship between fractures and DXA measures of BMD in the distal femur of children and adolescents with cerebral palsy or muscular dystrophy. J Bone Miner Res. 2010 Mar; 25(3):520-6.
James (Jim) J. Collins, MD, PhD
Assistant Professor, UC Department of Pediatrics
Congenital muscular dystrophies; merosin-deficient congenital muscular dystrophy
Collins J and Bönneman CG. Congenital Muscular Dystrophies: Toward Molecular Therapeutic Intervention. Current Neurology and Neuroscience Reports. 2010 Mar;10(2):83-91.
Collins J, Tang LY, Dimmock D, Morehart P, Bove K, Wong LJC, Wong B. Progressive myofiber changes of a childhood mitochondrial DNA depletion syndrome with a novel Thymidine Kinase 2 gene mutation. Neuromuscul Disord. 2009;19:784-787.
Irina Rybalsky, MD, PhD Staff Physician
John Lynn Jefferies, MD, MPH, FAAP, FACC Director, Advanced Heart Failure and Cardiomyopathy
Director, Advanced Heart Failure and Cardiomyopathy
Dr. Jefferies, an associate professor of pediatric cardiology and adult cardiovascular diseases, is the director of Advanced Heart Failure / Cardiomyopathy within The Heart Institute at Cincinnati Children's Hospital Medical Center.
He completed his combined pediatric and adult cardiology training at the Baylor College of Medicine in Houston, Texas at the Texas Children's Hospital and the Texas Heart Institute. He has authored or co-authored over 100 peer-reviewed manuscripts and book chapters on cardiomyopathy, cardiovascular genetics, and adults with congenital heart disease.
His current research interests include heritable causes of vascular disease, novel drug therapies for advanced heart failure, novel gene discovery in cardiomyopathy, characterization and management of left ventricular noncompaction (LVNC), and early diagnosis and management of chemotherapy induced cardiotoxicity.
He is on the editorial board of the Texas Heart Institute Journal and is an active member of numerous professional organization including the Heart Failure Society of America, the American College of Cardiology and the American Heart Association.
Jefferies JL, Towbin JA. Dilated cardiomyopathy. Lancet. 2010 Feb;375(9716):752-62. Breinholt JP, Moulik M, Dreyer WJ, Denfield SW, Kim JJ, Jefferies JL, Rossano JW, Gates CM, Clunie SK, Bowles KR, Kearney DL, Bowles NE, Towbin JA. Viral epidemiologic shift in inflammatory heart disease: the increasing involvement of parvovirus B19 in the myocardium of pediatric cardiac transplant patients. J Heart Lung Transplant. 2010 Jul;29(7):739-46. Rossano JW, Morales DL, Zafar F, Denfield SW, Kim JJ, Jefferies JL, Dreyer WJ. Impact of antibodies against human leukocyte antigens on long-term outcome in pediatric heart transplant patients: An analysis of the United Network for Organ Sharing database. J Thorac Cardiovasc Surg. 2010 May 26.
Carlson P, Jefferies JL, Kearney D, Russell H. Refractory dilated cardiomyopathy associated with metastatic neuroblastoma. Pediatr Blood Cancer. 2010 Jun 29.
Shah AM, Jefferies JL, Rossano JW, Decker JA, Cannon BC, Kim JJ. Electrocardiographic abnormalities and arrhythmias are strongly associated with the development of cardiomyopathy in muscular dystrophy. Heart Rhythm. 2010 Jun 18. Moulik M, Breinholt JP, Dreyer WJ, Kearney DL, Price JF, Clunie SK, Moffett BS, Kim JJ, Rossano JW, Jefferies JL, Bowles KR, O'Brian Smith E, Bowles NE, Denfield SW, Towbin JA. Viral Endomyocardial Infection Is an Independent Predictor and Potentially Treatable Risk Factor for Graft Loss and Coronary Vasculopathy in Pediatric Cardiac Transplant Recipients. J Am Coll Cardiol. 2010 56:582-592.Shchelochkov OA, Li FY, Wang J, Zhan H, Towbin JA, Jefferies JL, Wong LJ, Scaglia F. Milder Clinical Course of Type IV 3-Methylglutaconic Aciduria Due to a Novel Mutation in TMEM70. Mol Genet Metab. 2010 101:282-285. Foerster SR, Canter CE, Cinar A, Sleeper LA, Webber SA, Pahl E, Kantor PF, Alvarez JA, Colan SD, Jefferies JL, Lamour JM, Margossian R, Messere JE, Rusconi PG, Shaddy RE, Towbin JA, Wilkinson JD, Lipshultz SE. Ventricular Remodeling and Survival are More Favorable for Myocarditis than for Idiopathic Dilated Cardiomyopathy in Childhood: An Outcomes Study from the Pediatric Cardiomyopathy Registry. Circ Heart Fail. 2010. Jefferies JL, Price JF, Morales DL. Mechanical support in childhood heart failure. Heart Fail Clin. 2010 Oct;6(4):559-73. Jefferies JL, Hoffman TM, Nelson DP. Heart failure treatment in the intensive care unit in children. Heart Fail Clin. 2010 Oct;6(4):531-58.
Thomas D. Ryan, MD, PhD Heart Failure Staff Physician
Heart Failure Staff Physician
Cardiomyopathy; heart failure; heart transplantation; mechanical circulatory support
Development of cardiomyopathy in at risk populations, including Duchenne muscular dystrophy and other genetic cardiomyopathies, and anthracycline exposure.
Thomas D Ryan, MD, PhD, was born and raised in Wichita, KS and graduated magna cum laude from Wichita State University in 1996 with a BS in Biological Sciences.
In 1997 he began training in the MD/PhD program at the University of Alabama at Birmingham, and studied the molecular, cellular, and whole organ aspects of cardiac remodeling in a rat model of volume overload. His general pediatrics residency training took place at Cincinnati Children’s Hospital Medical Center from 2006-2009, as did his Pediatric Cardiology fellowship training from 2009-2012 and advanced fellowship in Pediatric Heart Failure/Transplant from 2012-2013. His clinical and research interests focus on heart failure, cardiomyopathy, cardiac transplantation, and mechanical circulatory support.
BS: Wichita State University, Wichita, KS, 1996.
PhD: University of Alabama at Birmingham, Birmingham, AL, 2004.
MD: University of Alabama at Birmingham, Birmingham, AL, 2005.
Residency: Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2006-2009.
Fellowship: Pediatric Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2009-2012.
Advanced Fellowship: Pediatric Heart Failure/Transplant, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2012-2013.
Certification: American Board of Pediatrics, 2010; American Board of Pediatrics, Sub-board of Pediatric Cardiology, 2012.
Ryan TD, Gupta D, Gupta A, Goldenberg P, Taylor MD, Lorts A, Jefferies JL. Cardiomyopathy in a Patient with Russell-Silver Syndrome. Cardiovasc Path. 2013 Sep 24. Epub ahead of print.
Ryan TD, Taylor MD, Wojciech M, Cripe LH, Pratt J, King EC, Lao K, Grenier MA, Jefferies JL, Benson DW, Hor KH. Abnormal circumferential strain is present in young Duchenne muscular dystrophy patients. Pediatric Cardiol. 2013 Jun;34(5):1159-65.
Ryan TD, Ware SM, Lucky AW, Towbin JA, Jefferies JL, Hinton RB. Left ventricular noncompaction cardiomyopathy and aortopathy in a patient with recessive dystrophic epidermolysis bullosa. Circ Heart Fail. 2012 Sep 1;5(5):e81-2.
Ryan TD, Rothstein EC, Aban I, Tallaj JA, Husain A, Lucchesi PA, Dell'Italia LJ. Left ventricular eccentric remodeling and matrix loss are mediated by bradykinin and precede cardiomyocyte elongation in rats with volume overload. J Am Coll Cardiol. 2007 Feb 20;49(7):811-21.
Ryan TD, Dimmitt RA, Tubbs RS, Roberts OA, Choi H, Loukas M, Blount JP. Contribution of surgical evacuation of a large subgaleal hematoma to the resolution of severe conjugated hyperbilirubinemia in a neonate. Case report. J Neurosurg. 2007 Feb;106(2 Suppl):131-3.
Jeffrey A. Towbin, MD, FAAP, FACC, FAHA Executive Co-Director, Heart Institute; Chief, Pediatric Cardiology
Executive Co-Director, Heart Institute; Chief, Pediatric Cardiology
Director, Heart Institute Diagnostic Laboratory
BS: Biology, University of Cincinnati, 1974.MS: Cell Biology, University of Cincinnati, 1977.MD: University of Cincinnati, 1982.
Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, 1985.
Fellowship: Pediatric Cardiology, Baylor College of Medicine, Texas Children's Hospital, 1989.
McBride KL, Zender GA, Fitzgerald-Butt SM, Seagraves NJ, Fernbach SD, Zapata G, Lewin M, Towbin JA, Belmont JW. Association of common variants in ERBB4 with congenital left ventricular outflow tract obstruction defects. Birth Defects Res A Clin Mol Teratol. 2011 Mar;91(3):162-8.
Fakhro KA, Choi M, Ware SM, Belmont JW, Towbin JA, Lifton RP, Khokha MK, Brueckner M. Rare copy number variations in congenital heart disease patients identify unique genes in left-right patterning. Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2915-20.
Goldenberg I, Horr S, Moss AJ, Lopes CM, Barsheshet A, McNitt S, Zareba W, Andrews ML, Robinson JL, Locati EH, Ackerman MJ, Benhorin J, Kaufman ES, Napolitano C, Platonov PG, Priori SG, Qi M, Schwartz PJ, Shimizu W, Towbin JA, Vincent GM, Wilde AA, Zhang L. Risk for life-threatening cardiac events in patients with genotype-confirmed long-QT syndrome and normal-range corrected QT intervals. J Am Coll Cardiol. 2010 Dec 28;57(1):51-9.
Towbin JA, Ware SM, Jefferies JL. Heart transplants in pediatric patients: viral infection as a loss predictor. Future Cardiol. 2010 Nov;6(6):735-41.
Foerster SR, Canter CE, Cinar A, Sleeper LA, Webber SA, Pahl E, Kantor PF, Alvarez JA, Colan SD, Jefferies JL, Lamour JM, Margossian R, Messere JE, Rusconi PG, Shaddy RE, Towbin JA, Wilkinson JD, Lipshultz SE. Ventricular remodeling and survival are more favorable for myocarditis than for idiopathic dilated cardiomyopathy in childhood: an outcomes study from the Pediatric Cardiomyopathy Registry. Circ Heart Fail. 2010 Nov 1;3(6):689-97.
Purevjav E, Varela J, Morgado M, Kearney DL, Li H, Taylor MD, Arimura T, Moncman CL, McKenna W, Murphy RT, Labeit S, Vatta M, Bowles NE, Kimura A, Boriek AM, Towbin JA. Nebulette mutations are associated with dilated cardiomyopathy and endocardial fibroelastosis. J Am Coll Cardiol. 2010 Oct 26;56(18):1493-502. Towbin JA. Left ventricular noncompaction: a new form of heart failure. Heart Fail Clin. 2010 Oct;6(4):453-69 Towbin JA. Preface: Heart failure in children. Heart Fail Clin. 2010 Oct;6(4):xvii-iii.
Wilkinson JD, Landy DC, Colan SD, Towbin JA, Sleeper LA, Orav EJ, Cox GF, Canter CE, Hsu DT, Webber SA, Lipshultz SE. The pediatric cardiomyopathy registry and heart failure: key results from the first 15 years. Heart Fail Clin. 2010 Oct;6(4):401-13 Towbin JA. Hypertrophic cardiomyopathy. Pacing Clin Electrophysiol. 2009 Jul;32 Suppl 2:S23-31.
Susan R. Rose, MD
Professor, UC Department of Pediatrics
Hypothalamic pituitary function; thyroid; disorders of growth or puberty; endocrine function in cancer survivors after head injury
MD: Case Western Reserve School of Medicine, 1980.
MEd: School Psychology, University of Dayton, 1972.
Residency: The Cleveland Clinic, 1983.
Fellowship: National Institutes of Health, 1986.
Certification: Pediatrics, 1985; Pediatric Endocrinology, 1986.
Slaughter JL, Meinzen-Derr J, Rose SR, Leslie ND, Chandrasekar R, Linard SM, Akinbi HT. The effects of gestational age and birth weight on false-positive newborn-screening rates. Pediatrics. 2010 Nov;126(5):910-6.
Kaulfers AM, Backeljauw PF, Reifschneider K, Blum S, Michaud L, Weiss M, Rose SR. Endocrine dysfunction following traumatic brain injury in children. J Pediatr. 2010 Dec;157(6):894-9.
Rose SR. Improved diagnosis of mild hypothyroidism using time-of-day normal ranges for thyrotropin. J Pediatr. 2010 Oct;157(4):662-7; 667.e1.
van der Kaay DC, de Jong FH, Rose SR, Odink RJ, Bakker-van Waarde WM, Sulkers EJ, Hokken-Koelega AC. Overnight levels of luteinizing hormone, follicle-stimulating hormone and growth hormone before and during gonadotropin-releasing hormone analogue treatment in short boys born small for gestational age. Horm Res. 2009;71(5):260-7. van der Kaay DC, Rose SR, van Dijk M, Noordam C, van Rheenen E, Hokken-Koelega AC. Reduced levels of GH during GnRH analogue treatment in pubertal short girls born small for gestational age (SGA). Clin Endocrinol (Oxf). 2009 Jun;70(6):914-9.
Dorn LD, Rose SR, Rotenstein D, Susman EJ, Huang B, Loucks TL, Berga SL. Differences in endocrine parameters and psychopathology in girls with premature adrenarche versus on-time adrenarche. J Pediatr Endocrinol Metab. 2008 May;21(5):439-48.
Eyal O, Blum S, Mueller R, Smith FO, Rose SR. Improved growth velocity during thyroid hormone therapy in children with Fanconi anemia and borderline thyroid function. Pediatr Blood Cancer. 2008 Nov;51(5):652-6.
Rose SR. Use of GnRH agonists in GH-deficient patients: arguments for and against. The case against GnRH agonists in GH-deficient patients. Pediatr Endocrinol Rev. 2008 Feb;5 Suppl 2:744, 750-4.
Elder DA, D'Alessio DA, Eyal O, Mueller R, Smith FO, Kansra AR, Rose SR. Abnormalities in glucose tolerance are common in children with fanconi anemia and associated with impaired insulin secretion. Pediatr Blood Cancer. 2008 Aug;51(2):256-60.
Kazlauskaite R, Evans AT, Villabona CV, Abdu TA, Ambrosi B, Atkinson AB, Choi CH, Clayton RN, Courtney CH, Gonc EN, Maghnie M, Rose SR, Soule SG, Tordjman K; Consortium for Evaluation of Corticotropin Test in Hypothalamic-Pituitary Adrenal Insufficiency. Corticotropin tests for hypothalamic-pituitary- adrenal insufficiency: a metaanalysis. J Clin Endocrinol Metab. 2008 Nov;93(11):4245-53.
Meilan M. Rutter, MD, FRACP
Bone health and calcium metabolism; disorders of growth, puberty and sex development; endocrine function in cancer survivors; endocrine function in neuromuscular disorders
Insulin-like growth factor-1 (IGF-1) therapy in Duchenne Muscular Dystrophy
Meilan Rutter is board-certified in Pediatrics and Pediatric Endocrinology. She is an Assistant Professor of Pediatrics in the Division of Endocrinology, and joined the faculty of Cincinnati Children's Hospital Medical Center in 2008. Currently, Dr. Rutter is assistant director of the Pediatric Endocrinology Fellowship Program.
Dr. Rutter received her degrees of Bachelor of Medicine and Bachelor of Surgery (MB, BCh) from the University of Wales College of Medicine. She completed her training in Pediatrics in New Zealand, and was admitted to Fellowship of the Royal Australasian College of Physicians (FRACP) in 1995. She underwent fellowship training in Pediatric Endocrinology at Cincinnati Children's. She completed further pediatric residency training to achieve American Board of Pediatrics specialty and subspecialty board certification.
Dr. Rutter treats children and adolescents with endocrine disorders and diabetes mellitus. She serves as a consultant for the Neuromuscular Comprehensive Care Center and the Neuro-Oncology program at Cincinnati Children's. Additionally. she is a member of the Disorders of Sex Development interdisciplinary team.
MB, BCh: University of Wales College of Medicine, Cardiff, United Kingdom.FRACP: Royal Australasian College of Physicians, New Zealand.Residency: Auckland Children's Hospital and Dunedin Hospital, New Zealand; Cincinnati Children's, Cincinnati, OH.
Fellowship: Pediatric Endocrinology, Cincinnati Children's, Cincinnati, OH.
Certification: General Pediatrics, American Board of Pediatrics, 2002; Pediatric Endocrinology, American Board of Pediatrics, 2003; Pediatrics, Fellowship of the Royal Australasian College of Physicians, 1995.
Rose SR, Rutter MM, Mueller R, Harris M, Hamon B, Fletcher Bulluck A, Smith FO. Bone mineral density is normal in children with Fanconi anemia. Pediatric Blood & Cancer. 2011 Apr. Epub ahead of print.
Bianchi ML, Biggar D, Bushby K, Rogol AD, Rutter MM, Tseng B. Endocrine aspects of Duchenne Muscular Dystrophy. Neuromuscular Disorders. 2011;21(4):298-303.
Wong BL, Rutter MM, Rose SR, Clark E, Vonderhaar K. Growth hormone therapy in Duchenne Muscular Dystrophy. Best Evidence Statement, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio. 2009.
Rutter MM. What is an endocrinologist and why is endocrine care important for Duchenne? Action Duchenne newsletter. 2009.
Murray R, Rutter MM, Racine M, Rose SR. Report on The Endocrine Society’s 90th Annual Meeting. Highlights. 2008;16(4):1-36.
Rutter MM, Racine M, Rose SR. Report on The Endocrine Society’s 89th Annual Meeting. Highlights. 2007;15(3):2-30.
Rutter MM, Rose SR. Long-term endocrine sequelae of childhood cancer. Curr Opin Pediatr. 2007 Aug;19(4):480-7.
Rutter MM, Markoff E, Clayton L, Akeno N, Zhao G, Clemens TL, Chernausek SD. Osteoblast-specific expression of insulin-like growth factor-1 in bone of transgenic mice induces insulin-like growth factor binding protein-5. Bone. 2005 Feb;36(2):224-31.
Rutter MM, Prahalad S, Passo M, Backeljauw PF. Idiopathic hypercalcemia and eosinophilic fasciitis: a novel association. J Pediatr Endocrinol Metab. 2004 Sep;17(9):1251-4.
Rutter MM, Smith EP. Pseudohypoparathyroidism type Ia: late presentation with intact mental development. J Bone Miner Res. 1998 Jul;13(7):1208-9.
Ajay Kaul, MBBS, MD
Kaul A, Garza JM, Connor FL, Cocjin JT, Flores AF, Hyman PE, Di Lorenzo C. Colonic Hyperactivity Results in Frequent Fecal Soiling in a Subset of Children After Surgery for Hirschsprung Disease. J Pediatr Gastroenterol Nutr. 2011 Jan 12.
Blanchard C, Stucke EM, Rodriguez-Jimenez B, Burwinkel K, Collins MH, Ahrens A, Alexander ES, Butz BK, Jameson SC, Kaul A, Franciosi JP, Kushner JP, Putnam PE, Abonia JP, Rothenberg ME. A striking local esophageal cytokine expression profile in eosinophilic esophagitis. J Allergy Clin Immunol. 2011 Jan;127(1):208-17, 217.e1-7.
Garza JM, Kaul A. Gastroesophageal reflux, eosinophilic esophagitis, and foreign body. Pediatr Clin North Am. 2010 Dec;57(6):1331-45. Review.
Zhu X, Wang M, Mavi P, Rayapudi M, Pandey AK, Kaul A, Putnam PE, Rothenberg ME, Mishra A. Interleukin-15 expression is increased in human eosinophilic esophagitis and mediates pathogenesis in mice. Gastroenterology. 2010 Jul;139(1):182-93.e7.
Caldwell JM, Blanchard C, Collins MH, Putnam PE, Kaul A, Aceves SS, Bouska CA, Rothenberg ME. Glucocorticoid-regulated genes in eosinophilic esophagitis: a role for FKBP51. J Allergy Clin Immunol. 2010 Apr;125(4):879-888.e8.
Blanchard C, Stucke EM, Burwinkel K, Caldwell JM, Collins MH, Ahrens A, Buckmeier BK, Jameson SC, Greenberg A, Kaul A, Franciosi JP, Kushner JP, Martin LJ, Putnam PE, Abonia JP, Wells SI, Rothenberg ME. Coordinate interaction between IL-13 and epithelial differentiation cluster genes in eosinophilic esophagitis. J Immunol. 2010 Apr 1;184(7):4033-41.
Jafri M, Alonso M, Kaul A, Dierig J, Racadio J, Inge T, Brown R, Ryckman F, Tiao G. Intraoperative manometry during laparoscopic Heller myotomy improves outcome in pediatric achalasia. J Pediatr Surg. 2008 Jan;43(1):66-70; discussion 70.
Pentiuk SP, Miller CK, Kaul A. Eosinophilic esophagitis in infants and toddlers. Dysphagia. 2007 Jan;22(1):44-8.
Boesch RP, Daines C, Willging JP, Kaul A, Cohen AP, Wood RE, Amin RS. Advances in the diagnosis and management of chronic pulmonary aspiration in children. Eur Respir J. 2006 Oct;28(4):847-61. Review.
Bates MD, Dunagan DT, Welch LC, Kaul A, Harvey RP. The Hlx homeobox transcription factor is required early in enteric nervous system development. BMC Dev Biol. 2006 Jul 19;6:33.
Elizabeth A. Ulm, LGC Genetic Counselor, Division of Human Genetics
Elizabeth C. Jackson, MD Director, Healthy Bladder Clinic
Director, Healthy Bladder Clinic
Elizabeth C. Jackson, MD, is a pediatric nephrologist recognized in the need for bladder management. Dr. Jackson has recently discontinued her inpatient nephrology role, and is currently focused on outpatient lower urinary tract management. She is the director of the Healthy Bladder Clinic at Cincinnati Children's. The Healthy Bladder Clinic cares for children with functional lower urinary tract disorders. There are more than 1200 visits per year to this clinic.
Ivancić V, Defoor W, Jackson E, Alam S, Minevich E, Reddy P, Sheldon C. Progression of renal insufficiency in children and adolescents with neuropathic bladder is not accelerated by lower urinary tract reconstruction. J Urol. 2010 Oct;184(4 Suppl):1768-74.
DeFoor WR, Jackson E, Minevich E, Caillat A, Reddy P, Sheldon C, Asplin J. The risk of recurrent urolithiasis in children is dependent on urinary calcium and citrate. Urology. 2010 Jul;76(1):242-5.
DeFoor W, Clark C, Jackson E, Reddy P, Minevich E, Sheldon C. Risk factors for end stage renal disease in children with posterior urethral valves. J Urol. 2008 Oct;180(4 Suppl):1705-8; discussion 1708.
DeFoor W, Minevich E, Jackson E, Reddy P, Clark C, Sheldon C, Asplin J. Urinary metabolic evaluations in solitary and recurrent stone forming children. J Urol. 2008 Jun;179(6):2369-72.
DeFoor W, Asplin J, Jackson E, Jackson C, Reddy P, Sheldon C, Erhard M, Minevich E. Urinary metabolic evaluations in normal and stone forming children. J Urol. 2006 Oct;176(4 Pt 2):1793-6.
Defoor W, Asplin J, Jackson E, Jackson C, Reddy P, Sheldon C, Minevich E. Results of a prospective trial to compare normal urine supersaturation in children and adults. J Urol. 2005 Oct;174(4 Pt 2):1708-10.
Jensen S, Jackson EC, Riley L, Reddy S, Goebel J. Tacrolimus-based immunosuppression with steroid withdrawal in pediatric kidney transplantation -- 4-year experience at a moderate-volume center. Pediatr Transplant. 2003 7:119-124.
Strife CF, Prada AL, Clardy CW, Jackson E, Forristal J. Autoantibody to complement neoantigens in membranoproliferative glomerulonephritis. J Pediatr. 1990 May;116(5):S98-102.
Barbara J. Godshall, MMSc, RD, CSP, LD, CD, CNSC Registered Dietitian, Comprehensive Neuromuscular Center
Registered Dietitian, Comprehensive Neuromuscular Center
Registered Dietitian, Division of Nutrition Therapy
Neuromuscular diseases and nutrition management
Ms. Godshall has held positions at Duke University Medical Center, Durham, NC, Incarnate Word Hospital, St. Louis, MO, James Whitcomb Riley Hospital For Children, Indianapolis, IN, and The Community Health Network, Indianapolis, IN prior to coming to Cincinnati Children’s Hospital Medical Center. While at James Whitcomb Riley Hospital for Children, Ms. Godshall completed nutrition research with children with Wilms’ tumor and children with Neuroblastoma. While at The Community Health Network, Ms. Godshall was the Neonatal Dietitian for their 36 bed Neonatal Intensive Care Unit. Since coming to Cincinnati Children’s Hospital Medical Center, Ms. Godshall started in the Comprehensive Neuromuscular Center, providing nutrition care to children with neuromuscular diseases. Her primary interests were children with Duchenne Muscular Dystrophy and children with Spinal Muscular Atrophy.
Ms. Godshall is currently serving on the Medical Advisory Committee for the Families of SMA. In the summer of 2010, Ms. Godshall accepted the role of clinical manager in the Division of Nutrition Therapy.
MMSc: Indiana University School of Medicine, Masters of Medical Science in Pediatric Nutrition, 1987
Fellowship: Perinatal Neonatal Nutrition Training, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, 1984
Certifications: Certified Specialist in Pediatrics (CSP) 2004, Certified Nutrition Support Clinician (CNSC) 2005
Rickard KA, Godshall BJ, Lopez AL, Weetman RM, Childhood cancer. In: Merritt, R, ed. Aspen Nutrition Support Manual. 1st ed. Baltimore, MD, Aspen Publications, 1998.
Alexander HR, Rickard KA, Godshall BJ. Nutritional supportive care. In: Pizzo PA, Poplack DG, eds. Principles and Practice of Pediatric Oncology. 3rd ed. Philadelphia, PA: Lippincott-Raven Publishers; 1997:1167-1182.
Rickard KA, Godshall BJ, Nutrition Strategies for Children with Cancer, Nutrition Focus. Vol. 6, No. 5, September-October, 1991.
Rickard KA, Jaeger Godshall B, Loghmani ES, Coates TD, Grosfeld JL, Weetman RM, Detamore Lingard C, Foland BB, Yu P, McGuire W, Provisor AJ, Oei TO, Baehner RL. Integration of nutrition support into oncologic treatment protocols for high and low nutritional risk children with Wilms' tumor. A prospective randomized study. Cancer. 64(1):491-509, 1989.
Rickard, KA, Becker, MC, Loghmani E, Grosfeld, JL, Jaeger Godshall B, Weetman RM, Coates TD, Lingard CD, White NM, Foland B, Yu PU, McGuire W, Provisor AJ, Oei TO, Baehner RL. Effectiveness of two methods of parenteral nutrition support in improving muscle mass of children with neuroblastoma or Wilms's tumor. A randomized study. Cancer. 64(1): 116-24, 1989.
Viral V. Jain, MD Orthopaedic Surgeon
Spinal deformitie; minimally invasive spine surgeries; limb lengthening and reconstruction; pediatric hip disorders
Growth of immature spine; health of intervertebral disk
Wall EJ, Jain V, Vora V, Mehlman CT, Crawford AH. Complications of titanium and stainless steel elastic nail fixation of pediatric femoral fractures. J Bone Joint Surg Am. 2008 Jun;90(6):1305-13.
Jain V, Crawford A. Re: Hoernschemeyer D, Farjoodi P, Cheng J, et al. A study of the cutaneous nerves encountered during thoracoplasty. Letter to the Editor. Spine 2007 32:301-5.
Jain VV, Mehlman CT. Closed reduction and spica cast application for the treatment of femoral shaft fracture. In Wiesel S. Operative Techniques in Orthopedic Surgery. New York, Thieme.
Crawford AH, Jain VV. Neurofibromatosis. In Akbarnia B, Thompson G: Growing Spine: Management of Spine Disorders in the Young Child. Philadelphia, Lippincott Williams & Wilkins.
James J. McCarthy, MD Director, Pediatric Orthopaedic Surgery
Director, Pediatric Orthopaedic Surgery
Alvin Crawford Chair in Pediatric Orthopaedics
Professor, Division of Pediatric Surgery
Complex limb and spine deformities; scoliosis; pediatric hip disorders; neuromuscular disorders; cerebral palsy
Treatment of pediatric hip disorders; complex limb and spine deformities; gait analysis
James McCarthy, MD, completed his residency in at the Cleveland Clinic Foundation. He comes to Cincinnati Children’s from his most recent position as an Associate Professor with the Department of Orthopaedics and Rehabilitation at The University of Wisconsin School of Medicine and Rehabilitation in Madison, Wisconsin.
Peter F. Sturm, MD Director, Crawford Spine Center
Director, Crawford Spine Center
Alvin H. Crawford Chair of Spine Surgery
MD: New York University School of Medicine, New York, NY, 1981.
Residency: Orthopaedic Surgery Mount Sinai Hospital, New York, NY, 1986.
Fellowship: Russ Spinal Surgery, Ottawa Civic Hospital Ottawa, Ontario, Canada, 1987; Pediatric Orthopaedic Surgery, The Children's Hospital Boston, Boston, MA, 1988.
Certification: Orthopaedic Surgery, 1990, 1999, 2010.
Carreon LY, Sanders JO, Diab M, Sturm PF, Sucato DJ; Spinal Deformity Study Group. Patient satisfaction after surgical correction of adolescent idiopathic scoliosis. Spine (Phila Pa 1976). 2011 Jan 8.
Sturm PF, Zaharski K, Riordan M, Hassani S. Anticipating complications in pediatric deformity surgery: is any preparation necessary in healthy children? Spine (Phila Pa 1976). 2010 Dec 1;35(25):2211-4.
Carreon LY, Sanders JO, Diab M, Sucato DJ, Sturm PF, Glassman SD; Spinal Deformity Study Group. The minimum clinically important difference in Scoliosis Research Society-22 Appearance, Activity, And Pain domains after surgical correction of adolescent idiopathic scoliosis. Spine (Phila Pa 1976). 2010 Nov 1;35(23):2079-83.
Sanders JO, Carreon LY, Sucato DJ, Sturm PF, Diab M; Spinal Deformity Study Group. Preoperative and perioperative factors effect on adolescent idiopathic scoliosis surgical outcomes. Spine (Phila Pa 1976). 2010 Sep 15;35(20):1867-71. Bustamante Valles KD, Long JT, Riedel SA, Graf A, Krzak J, Hassani S, Riordan M, Zaharski K, Sturm PF, Harris GF. Analysis of postural stability following posterior spinal fusion in adolescents with idiopathic scoliosis. Stud Health Technol Inform. 2010;158:127-31.
Cahill PJ, Warnick DE, Lee MJ, Gaughan J, Vogel LE, Hammerberg KW, Sturm PF. Infection after spinal fusion for pediatric spinal deformity: thirty years of experience at a single institution. Spine (Phila Pa 1976). 2010 May 20;35(12):1211-7. Slavens BA, Sturm PF, Harris GF. Upper extremity inverse dynamics model for crutch-assisted gait assessment. J Biomech. 2010 Jul 20;43(10):2026-31. Valles KD, Long JT, Riedel SA, Graf A, Krzak J, Hassani S, Sturm PF, Harris GF. Using a bi-planar postural stability model to assess children with scoliosis. Conf Proc IEEE Eng Med Biol Soc. 2009;2009:7010-3. Slavens BA, Sturm PF, Bajournaite R, Harris GF. Upper extremity dynamics during Lofstrand crutch-assisted gait in children with myelomeningocele. Gait Posture. 2009 Nov;30(4):511-7. Sanders JO, D'Astous J, Fitzgerald M, Khoury JG, Kishan S, Sturm PF. Derotational casting for progressive infantile scoliosis. J Pediatr Orthop. 2009 Sep;29(6):581-7.
Mark Meyer, MD Anesthesiologist
Assistant Professor, UC Department of Anesthesia
Palliative medicine; end of life care; anesthesiology; pain management
Anesthesia; pain management
Mark Meyer, MD, is a board-certified anesthesiologist who completed his residency at the Cleveland Clinic in Cleveland, Ohio.
Dr. Meyer joined the Department of Anesthesia in 2003 following his Pediatric Anesthesia Fellowship at Cincinnati Children's Hospital Medical Center.
Dr. Meyer is a staff anesthesiologist, as well as an attending physician in the Division of Pain Management, caring for patients with acute pain. In addition, Dr. Meyer is an attending physician for StarShine Hospice, the pediatric hospice at Cincinnati Children's.
In 2006, Dr. Meyer received his board certification from the American Board of Hospice and Palliative Medicine. He has been an integral part of the development and implementation of the Pediatric Palliative and Comfort Care Team / PACT at Cincinnati Children's.
Dr. Meyer is the PACT consulting physician, partnering with families in order to offer a range of comprehensive, family-centered care for children with chronic, complex or life-threatening conditions.
Deborah W. Palmisano, MSW, LISW Social Worker, Pediatric Palliative Care Team / PACT
Norbert J. Weidner, MD Anesthesiologist
Medical Director, StarShine Hospice
Medical Director, Pediatric Palliative Care / PACT
Associate Professor, UC Department of Anesthesia
Norbert J. Weidner, MD, is a board-certified pediatrician as well as a board-certified anesthesiologist. Following training in pediatrics Cincinnati Children's Hospital Medical Center, as well as Dayton Children's Hospital, he pursued a fellowship in pediatric anesthesia/critical care/regional anesthesia in Melbourne, Australia, for one year.
Upon completion of his fellowship in 1988, Dr. Weidner joined the Department of Anesthesia at Cincinnati Children's. In addition to his staff duties as an anesthesiologist, Dr. Weidner was an attending staff in the pediatric intensive care unit for approximately two years.
To incorporate the fellowship training he received in Australia, Dr. Weidner began the pain management group at Cincinnati Children's. He has participated in the pain management group both in the care of acute postoperative pain as well as chronic pain management.
In 2004, Dr. Weidner received Board Certification with the American Board for Hospice and Palliative Medicine. Dr. Weidner has been affiliated with the hospice service at Cincinnati Children's since its inception and currently serves as StarShine Hospice's Medical Director .
Dr. Weidner is passionate about partnering with families to offer a range of comprehensive, family-centered care to children with chronic, complex or life-threatening conditions. His vision to address the needs of this patient population resulted in the development of the Pediatric Palliative and Comfort Care Team (PACT) here at Cincinnati Children's. Dr. Weidner serves as the director of this consulting service.
MD: Temple Medical School, Philadelphia, PA, 1975.
Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 1975-77; Pediatrics, Dayton Children's Hospital, Dayton, OH 1981-82; Anesthesia, University of Cincinnati College of Medicine, Cincinnati, OH, 1985-87.
Fellowship: Pediatric Anesthesia, Royal Children's Hospital, Melbourne, Australia, 1988.
Certification: American Board of Anesthesiology, 1983; American Board of Pediatrics, 1989; Diplomat, American Board Medical Acupuncture, 2001; Hospice and Palliative Medicine, 2004.
Goldschneider KR, Racadio JM, Weidner NJ. Celiac plexus blockade in children using a three-dimensional fluoroscopic reconstruction technique: case reports. Reg Anesth Pain Med. 2007 Nov-Dec;32(6):510-5. Weidner NJ. Pediatric palliative care. Curr Oncol Rep. 2007 Nov;9(6):437-9. Review Cripe LH, Barber BJ, Spicer RL, Wong BL, Weidner N, Benson DW, Markham LW. Outpatient continuous inotrope infusion as an adjunct to heart failure therapy in Duchenne muscular dystrophy. Neuromuscul Disord. 2006 Nov;16(11):745-8.
Weidner NJ. The evolution of pediatric palliative medicine and its integration with anesthesia. Int Anesthesiol Clin. 2006 Winter;44(1):109-18. Review. Weidner NJ. Developing an interdisciplinary palliative care plan for the patient with muscular dystrophy. Pediatr Ann. 2005 Jul;34(7):546-52. Review.
Rebeccah L. Brown, MD Associate Director, Trauma Services
Associate Director, Trauma Services
Associate Professor, UC Department of Surgery
General pediatric surgery; trauma; injury prevention; minimally invasive surgery; necrotizing enterocolitis; neonatal surgery; minimally invasive surgery; congenital hemolytic anemias; chest wall deformities
Pediatric trauma; injury prevention
Rebeccah L. Brown, MD, received a Bachelor of Science in Biology and Bachelor of Arts in Chemistry at New Mexico State University in Las Cruces, NM, in 1986. She graduated from University of New Mexico School of Medicine in Albuquerque, NM, with an MD in 1990. She completed her general surgery residency at University of Cincinnati Medical Center, in Cincinnati, Ohio, in 1997.
During her general surgical training, she also performed two years of basic science and clinical research in burn injuries and wound healing at the Shriners Hospitals for Children -- Cincinnati. She also served as an extracorporeal membrane oxygenation (ECMO) fellow at Cincinnati Children's Hospital Medical Center.
After completion of general surgery training, Dr. Brown completed a two-year fellowship in Pediatric Surgery at Children's Hospital of Buffalo in Buffalo, N.Y. She returned to Cincinnati Children's, Ohio, as assistant professor of Surgery and Pediatrics. Her main research interest is trauma and injury prevention, and she is currently the assistant director of Trauma Services, the fellowship director for the Pediatric Trauma Fellowship, and the director and cofounder of the Buckle Up for Life or Abrochate a la Vida program funded by Toyota.
Dr. Brown's clinical interests besides trauma and injury prevention include general pediatric surgery, minimally invasive surgery, inflammatory bowel disease, and Hirschsprung's disease.
Dr. Brown is a member of multiple professional organizations including the American College of Surgeons, American Medical Association, American Medical Women's Association, American College of Surgeons -- Ohio Chapter, Cincinnati Pediatric Society, Mont Reid Surgical Society, American Pediatric Surgical Association, American Academy of Pediatrics - Surgical Section and Injury Prevention Section, Eastern Association for the Surgery and Trauma, and Pediatric Trauma Society.
MD: University of New Mexico School of Medicine, Albuquerque, N.M., 1990.
Residency: General Surgery, University of Cincinnati Hospital, Cincinnati, Ohio, 1997.
Fellowship: Shriners Burns Institute, Cincinnati, Ohio, 1992-1994; ECMO, Children's Hospital Medical Center, Cincinnati, Ohio, 1993-1994; Pediatric Surgery Fellow, Children's Hospital of Buffalo, Buffalo, N.Y., 1997-1999.
Certification: Board-certified General Surgery, 1998, 2007; board-certified, Pediatric Surgery, 2000, 2009.
Victor F. Garcia, MD, FACS, FAAP Founding Director, Trauma Services
Founding Director, Trauma Services
Professor, UC Department of Surgery
Pediatric injury research and control; chest-wall deformities; minimally invasive surgery (use of the laparoscope and thoracoscope to diagnose and treat surgical diseases); surgical weight loss; minority health care
Victor Garcia, MD, graduated from West Point, the University of Pennsylvania School of Medicine, studied pediatric surgery under C Everett Koop, and was Walter Reed’s chief of General/Pediatric Surgery.
Vic founded Children’s Trauma Center and led the effort to establish the country’s first Pediatric Weight Loss Surgery Center.
For his ongoing work to eliminate childhood health and social disparities, he has received numerous awards and commendations to include the Martin Luther King Humanitarian Award and the National Jefferson Award.
Vic has an uncompromising belief in the power of systems thinking and stakeholder engagement to solve society’s most intractable problems.
BS: Engineering, United States Military Academy, 1964-1968.
MD: University of Pennsylvania, School of Medicine, Philadelphia, PA, 1974.Residency: Walter Reed Army Medical Center, Washington, DC, 1978. Fellowship: Children's Hospital of Philadelphia, Philadelphia, PA. Certification: Surgery, 1979; Pediatric Surgery, 1982; Surgical Critical Care, 1991.
Chatoorgoon K, Brown RL, Garcia VF, Falcone, RA. Role of Computed Tomography and Clinical Findings in Pediatric Blunt Intestinal Injury. Pediatric Emergency Care. 2012;28 (12): 1338-1342.
Beaudin M, Daugherty M, Geis G, Moody S, Brown RL, Garcia VF, Falcone RA. Assessment of Factors Associated with the Delayed Transfer of Pediatric Trauma Patients. Pediatric Emergency Care. 2012;28 (8): 758-63.
Goldberg J, McClaine RJ, Cook B, Garcia VF, Brown RL, Crone K, Falcone RA. Use of a mild traumatic brain injury guideline to reduce inpatient hospital imaging and charges. Journal of Pediatric Surgery. 2011;46: 1777-1783.
McClaine RJ, Garcia VF. Unnatural Causes: Social Determinants of Child Health and Well-being. The Pediatric Forum, American Medical Association. 2011;165 (5): 476.
Chatoorgoon K, Huezo K, Rangel E, Francios N, Schweer L, Daugherty M, Koehn M, Richetts C, Brown RL, Garcia VF, Falcone RA. Unnecessary Imaging, Not Hospital Distance, or Transportation Mode Impacts Delays in the Transfer of Injured Children. Pediatric Emergency Care. 2010;26 (7): 481-486.
Martin CA, Care M, Rangel EL, Brown RL, Garcia VF, Falcone RA. Severity of head computed tomography scan findings fail to explain racial differences in mortality following child abuse. American Journal of Surgery. 2010;199 (2): 210-215.
Ippisch HM, Inge TH, Daniels SR, Wang B, Khoury PR, Witt SA, Glascock BJ, Garcia VF, Kimball TR. Reversibility of Cardiac Abnormalities in Morbidly Obese Adolescents. Journal of the American College of Cardiology. 2008;51(14): 1342-1348.
Falcone RA , Martin C, Brown RL, Garcia VF. Despite overall low pediatric head injury mortality, disparities exist between races. Journal of Pediatric Surgery. 2008;43(10), 1858-1864.
Falcone RA, Daugherty M, Schweer L, Patterson M, Brown RL, Garcia VF. Multidisciplinary pediatric trauma team training using high-fidelity trauma simulation. Journal of Pediatric Surgery. 2008;43(6), 1065-1071.
Rangel SJ, Martin CA, Brown RL, Garcia VF, Falcone RA. Alarming trends in the improper use of motor vehicle restraints in children: implications for public policy and the development of race-based strategies for improving compliance. Journal of Pediatric Surgery. 2008;43(1), 200-207.
Thomas H. Inge, MD, PhD, FACS, FAAP Surgical Director, Surgical Weight Loss Program for Teens
Surgical Director, Surgical Weight Loss Program for Teens
Director, Center for Bariatric Research and Innovation
Attending Surgeon, Cincinnati Children’s Hospital Medical Center
Obesity surgery and research; neonatal surgery; gastroesophageal reflux disease; minimally invasive surgery; thoracic surgery
Thomas H. Inge, MD, PhD, is a Virginia native who grew up in a rural, farming community in Dinwiddie County. He received his BS in biology at the College of William and Mary in Williamsburg, VA, in 1987. Dr. Inge entered the Medical College of Virginia in Richmond, VA, in the Medical Scientist Training Program, and pursued degrees in microbiology/immunology and medicine. He graduated with MD and PhD degrees in 1993.
Dr. Inge received his surgical training at Stanford University Hospital in Palo Alto, CA, where he developed an interest in pediatric surgery. At the completion of his chief resident year in 1998, he moved to Birmingham, AL, for specialty training in pediatric surgery at the Children's Hospital of Alabama, with an emphasis on pediatric minimally invasive surgery. Dr. Inge became a full-time member of the surgical staff at Cincinnati Children's Hospital Medical Center and faculty member of the University of Cincinnati College of Medicine, Department of Surgery, Division of Pediatric Surgery, in July 2000.
In addition to general pediatric surgical practice, Dr. Inge's clinical research focus is related to bariatric surgery in adolescents. He is the surgical director of the Surgical Weight Loss Program for Teens, offering surgery for overweight adolescents with complications from their excess weight. He has served as a consultant to the Food and Drug Administration for projects related to device treatment of pediatric obesity. He is also the Principal Investigator of two research projects funded by National Institutes of Health (NIH) and co-investigator of another NIH funded project examining the role of surgery for management of adolescent obesity. He currently serves as Study Chairman of Teen-LABS, a multicenter research consortium examining outcomes of adolescent bariatric surgery.
Dr. Inge has given over 50 invited lectures nationally and internationally over the past four years, has mentored more than a dozen fellows and students, and has authored more than 70 published chapters and manuscripts.
BS: College of William and Mary, Williamsburg, VA, 1987.MD: Medical College of Virginia, Virginia Commonwealth University, Richmond, VA, 1993.PhD: Virginia Commonwealth University, Richmond, VA, 1993.Residency: Stanford University Hospital, Stanford, CA, 1998.
Fellowship: Children's Hospital of Alabama, Birmingham, AL, 2000.
Board Certification: Diplomate of the American Board of Surgery, December 1999; Certification in Pediatric Surgery, American Board of Surgery, March 2002.
Zeller MH, Guilfoyle SM, Reiter-Purtill J, Ratcliff MB, Inge TH, Long JD. Adolescent bariatric surgery: caregiver and family functioning across the first postoperative year. Surg Obes Relat Dis. 2010 Jul 29.
Ratcliff MB, Reiter-Purtill J, Inge TH, Zeller MH. Changes in depressive symptoms among adolescent bariatric candidates from preoperative psychological evaluation to immediately before surgery. Surg Obes Relat Dis. 2011 Jan-Feb;7(1):50-4.
Inge TH, Xanthakos S. Sleeve gastrectomy for childhood morbid obesity: why not? Obes Surg. 2010 Jan;20(1):118-20.
Inge TH, Jenkins TM, Zeller M, Dolan L, Daniels SR, Garcia VF, Brandt ML, Bean J, Gamm K, Xanthakos SA. Baseline BMI is a strong predictor of nadir BMI after adolescent gastric bypass. J Pediatr. 2010 Jan;156(1):103-108.e1.
Miyano G, Kalra M, Inge TH. Adolescent paraplegia, morbid obesity, and pickwickian syndrome: outcome of gastric bypass surgery. J Pediatr Surg. 2009 Mar;44(3):e41-4.
Zeller MH, Modi AC, Noll JG, Long JD, Inge TH. Psychosocial functioning improves following adolescent bariatric surgery. Obesity (Silver Spring). 2009 May;17(5):985-90.
Inge TH, Miyano G, Bean J, Helmrath M, Courcoulas A, Harmon CM, Chen MK, Wilson K, Daniels SR, Garcia VF, Brandt ML, Dolan LM. Reversal of type 2 diabetes mellitus and improvements in cardiovascular risk factors after surgical weight loss in adolescents. Pediatrics. 2009 Jan;123(1):214-22.
Modi AC, Loux TJ, Bell SK, Harmon CM, Inge TH, Zeller MH. Weight-specific health-related quality of life in adolescents with extreme obesity. Obesity (Silver Spring). 2008 Oct;16(10):2266-71.
Ippisch HM, Inge TH, Daniels SR, Wang B, Khoury PR, Witt SA, Glascock BJ, Garcia VF, Kimball TR. Reversibility of cardiac abnormalities in morbidly obese adolescents. J Am Coll Cardiol. 2008 Apr 8;51(14):1342-8.
Inge TH. Childhood obesity--a problem of surgical proportions? Nat Clin Pract Gastroenterol Hepatol. 2008 Apr;5(4):180-1.
Kevin E. Bove, MD
Professor, Division of Pediatric Pathology
Dr. Bove's current research focus is on pathogenesis of biliary atresia and other cholestatic disorders of infancy. He has long term research interests in the early stages of childhood neoplasia and childhood diseases of skeletal muscle and heart.
Dr. Bove has been a career academic pediatric pathologist at Cincinnati Children's since 1968. He functions as a surgical pathologist, autopsy consultant and electron microscopist with diverse clinical interests. His collaborations with faculty and fellows in many divisions have resulted in more than 180 peer-reviewed and more than 120 publications.
Kevin E. Bove, MD, has 32 years experience as a pediatric pathologist at Cincinnati Children's Hospital Medical Center.
Dr. Bove has achieved national recognition as an expert in tumors; neuromuscular diseases; liver diseases of children and performance / interpretation of pediatric autopsies.
Dr. Bove has and continues to be involved in leadership positions in the Society for Pediatric Pathology and the College of American Pathologists.
MD: State University of New York, Buffalo, NY.
Residency: Rotating Intern, Cincinnati General Hospital, 1961-1962; Pathology, Cincinnati General Hospital, 1962-1966.
Certification: American Board of Pathology in Anatomic and Clinical Pathology, 1967 and 1968; Pediatric Pathology, 1990.
Lili Miles, MD Staff Pathologist
Director, Fellowship Training Program
Associate Professor, Division of Pediatric Pathology
Pediatric pathology; pediatric neuropathology; pediatric neuromuscular disease
Mitochondrial diseases; coenzyme Q10; pediatric brain tumors; classification and grading of cortical dysplasia; hepatic pathology in pediatric NASH patients and animal models
Seo JH, Holland K, Rose D, Rozhkov L, Fujiwara H, Byars A, Arthur T, DeGrauw T, Leach JL, Gelfand MJ, Miles L, Mangano FT, Horn P, Lee KH. Multimodality imaging in the surgical treatment of children with nonlesional epilepsy. Neurology. 2011 Jan 4;76(1):41-8.
Phillips CL, Miles L, Jones BV, Sutton M, Crone K, Fouladi M. Medulloblastoma with melanotic differentiation: case report and review of the literature. J Neurooncol. 2010 Oct 16.
Miles MV, Putnam PE, Miles L, Tang PH, DeGrauw AJ, Wong BL, Horn PS, Foote HL, Rothenberg ME. Acquired coenzyme Q10 deficiency in children with recurrent food intolerance and allergies. Mitochondrion. 2011 Jan;11(1):127-35.
Kohli R, Kirby M, Xanthakos SA, Softic S, Feldstein AE, Saxena V, Tang PH, Miles L, Miles MV, Balistreri WF, Woods SC, Seeley RJ. High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis. Hepatology. 2010 Sep;52(3):934-44.
McAuliffe JJ, Loepke AW, Miles L, Joseph B, Hughes E, Vorhees CV. Desflurane, isoflurane, and sevoflurane provide limited neuroprotection against neonatal hypoxia-ischemia in a delayed preconditioning paradigm. Anesthesiology. 2009 Sep;111(3):533-46.
Kurth CD, McCann JC, Wu J, Miles L, Loepke AW. Cerebral oxygen saturation-time threshold for hypoxic-ischemic injury in piglets. Anesth Analg. 2009 Apr;108(4):1268-77.
Loepke AW, Istaphanous GK, McAuliffe JJ 3rd, Miles L, Hughes EA, McCann JC, Harlow KE, Kurth CD, Williams MT, Vorhees CV, Danzer SC. The effects of neonatal isoflurane exposure in mice on brain cell viability, adult behavior, learning, and memory. Anesth Analg. 2009 Jan;108(1):90-104.
Miles L, DeGrauw TJ, Dinopoulos A, Cecil KM, van der Knaap MS, Bove KE. Megalencephalic leukoencephalopathy with subcortical cysts: a third confirmed case with literature review. Pediatr Dev Pathol. 2009 May-Jun;12(3):180-6.
Miles MV, Tang PH, Miles L, Steele PE, Moye MJ, Horn PS. Validation and application of an HPLC-EC method for analysis of coenzyme Q10 in blood platelets. Biomed Chromatogr. 2008 Dec;22(12):1403-8.
Miles MV, Miles L, Tang PH, Horn PS, Steele PE, DeGrauw AJ, Wong BL, Bove KE. Systematic evaluation of muscle coenzyme Q10 content in children with mitochondrial respiratory chain enzyme deficiencies. Mitochondrion. 2008 Mar;8(2):170-80.
Ann E. McCormick, PT, PhD, NCS Physical Therapist II, Division of Occupational Therapy and Physical Therapy
Michelle N. McGuire, PT, MPT Coordinator, Division of Occupational Therapy and Physical Therapy
Raouf S. Amin, MD Director, Division of Pulmonary Medicine
Director, Division of Pulmonary Medicine
Director, Rare Lung Diseases Program
Raouf S. Amin, MD, is a professor of pediatrics at Cincinnati Children's Hospital Medical Center and the director of the Division of Pulmonary Medicine. He graduated from the University of Ain Shams in Cairo Egypt in 1977. Dr. Amin received clinical training in the United Kingdom and the United States. He completed a pulmonary fellowship at Cincinnati Children's Hospital Medical Center in 1993. His research focus is on cardiovascular morbidity of sleep disordered breathing in children. He has several funded protocols from the National Institute of Health.
MD: Aim Shams University, Cairo Egypt, 1978.
Residency: Pediatrics; Michigan State University, Flint, MI.
Certification: Pediatrics 1990; Pediatric Pulmonary Medicine 1994; Sleep Medicine 1995.
Clancy JP, Rowe SM, Accurso FJ, Aitken ML, Amin RS, Ashlock MA, Ballmann M, Boyle MP, Bronsveld I, Campbell PW, Deboeck K, Donaldson SH, Dorkin HL, Dunitz JM, Durie PR, Jain M, Leonard A, McCoy KS, Moss RB, Pilewski JM, Rosenbluth DB, Rubenstein RC, Schechter MS, Botfield M, Ordoñez CL, Spencer-Green GT, Vernillet L, Wisseh S, Yen K, Konstan MW. Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation. Thorax. 2011 Aug 8. Epub ahead of print.
Sung V, Beebe DW, Vandyke R, Fenchel MC, Crimmins NA, Kirk S, Hiscock H, Amin R, Wake M. Does sleep duration predict metabolic risk in obese adolescents attending tertiary services? A cross-sectional study. Sleep. 2011 Jul 1;34(7):891-8.
Sawnani H, Murugappan S, Gutmark E, Donnelly LF, Amin R, Mylavarapu G, Mihaescu M, Khosla S, Kalra M. Influence of gender on pharyngeal airway length in obese adolescents. Ann Otol Rhinol Laryngol. 2010 Dec;119(12):842-7.
Beebe DW, Ris MD, Kramer ME, Long E, Amin R. The association between sleep disordered breathing, academic grades, and cognitive and behavioral functioning among overweight subjects during middle to late childhood. Sleep. 2010 Nov 1;33(11):1447-56.
Beebe DW, Rose D, Amin R. Attention, learning, and arousal of experimentally sleep-restricted adolescents in a simulated classroom. J Adolesc Health. 2010 Nov;47(5):523-5.
McPhail GL, Weiland J, Acton JD, Ednick M, Chima A, VanDyke R, Fenchel MC, Amin RS, Seid M. Improving evidence-based care in cystic fibrosis through quality improvement. Arch Pediatr Adolesc Med. 2010 Oct;164(10):957-60.
McPhail GL, Ednick MD, Fenchel MC, VanDyke R, Chima A, Amin RS, Seid M. Improving follow-up in hospitalised children. Qual Saf Health Care. 2010 Oct;19(5):e35.
Ednick M, Cohen AP, McPhail GL, Beebe D, Simakajornboon N, Amin RS. A review of the effects of sleep during the first year of life on cognitive, psychomotor, and temperament development. Sleep. 2009 Nov 1;32(11):1449-58.
Ednick M, Tinkle BT, Phromchairak J, Egelhoff J, Amin R, Simakajornboon N. Sleep-related respiratory abnormalities and arousal pattern in achondroplasia during early infancy. J Pediatr. 2009 Oct;155(4):510-5.
McConnell K, Somers VK, Kimball T, Daniels S, VanDyke R, Fenchel M, Cohen A, Willging P, Shamsuzzaman A, Amin R. Baroreflex gain in children with obstructive sleep apnea. Am J Respir Crit Care Med. 2009 Jul 1;180(1):42-8.
Hemant Sawnani, MD Division of Pulmonary Medicine
Division of Pulmonary Medicine
Pediatric sleep disorders
MD: Seth GS Medical College/King Edward VIII Memorial Hospital, 1997.
Residency: Pediatrics, Brooklyn Hospital Medical Center, New York NY, 2000.
Fellowship: Pediatric Pulmonology, Tulane Medical Center, New Orleans LA, 2003; Sleep Medicine, Cincinnati Children's Hospital, Cincinnati OH, 2008.
Certification: Pediatrics, 2000, recertified 2007; Pediatric Pulmonology, 2004.
Lainie K. Holman, MD Staff Physician
Traumatic brain injury; spasticity management; acupuncture
Mary A. McMahon, MD Director, Division of Physical Medicine and Rehabilitation
Director, Division of Physical Medicine and Rehabilitation
Program Director, Physical Medicine and Rehabilitation Residency Program
Neuromuscular disorders; myelomeningocele
Jeffery D. Molkentin, PhD Professor | Howard Hughes Medical Institute Investigator
Professor | Howard Hughes Medical Institute Investigator
Davis J, Burr AR, Davis GF, Birnbaumer L, Molkentin JD. A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo. Dev. Cell 2012. 23:705-715.
Auger-Messier M, Accornero F, Goonasekera SA, Bueno OF, Lorenz JN, van Berlo JH, Willette RN, Molkentin JD. Unrestrained p38 MAPK Activation in Dusp1/4 Double Null Mice Induces Cardiomyopathy. Circ Res. 2012. In Press.
Lorts A, Schwanekamp JA, Baudino TA, McNally EM, Molkentin JD. Deletion of periostin reduced muscular dystrophy and fibrosis in mice by modulating the transforming growth factor-b pathway. Proc Natl Acad Sci USA. 2012. 109:10978-10983
Lynch JM, Maillet M, Vanhoutte D, Schloemer A, Sargent MA, Blair NS, Lynch KA, Okada T, Aronow BJ, Osinska H, Prywes R, Lorenz JN, Mori K, Lawler J, Robbins J, Molkentin JD. A thrombospondin-dependent pathway for a protective ER stress response. Cell. 2012. 149,1257-1268
Liu Q, Chen Y, Auger-Messier M, Molkentin JD. Interaction Between NFkB and NFAT Coordinates Cardiac Hypertrophy and Pathological Remodeling. Circ Res. 2012. 110:1077-1086
Goonasekera SA, Molkentin JD. Unraveling the secrets of a double life: Contractile versus signaling Ca(2+) in a cardiac myocyte. J Mol Cell Cardiol. 52:317-322. 2012.
Goonasekera SA, Hammer K, Auger-Messier M, Bodi I, Chen X, Zhang H, Reiken S, Elrod JW, Correll RN, York AJ, Sargent MA, Hofmann F, Moosmang S, Marks AR, Houser SR, Bers DM, Molkentin JD. Decreased cardiac L-type Ca2+ channel activity induces hypertrophy and heart failure in mice. J. Clin Invest. 2012. 122:280-290
Jessica A. Linck, MA, CCC-SLP Speech-Language Pathologist II, Division of Speech-Language Pathology
Elizabeth McCarty, OTR/L, ATP Occupational Therapist
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