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Many MDB laboratories use genetics and genomics in their research in a wide variety of ways. The power of next-generation sequencing techniques is often employed in either model systems or directly in clinical populations to gain insight into the mechanisms of development and disease. A major challenge in the current genomics age is to properly interpret these massive datasets and this is an active area of research in the field of bioinformatics.
Bruce Aronow, PhD, ProfessorIntegrative bioinformatics and genomics relevant to human health and disease [Visit the Aronow / Jegga Lab]
Artem Barski, PhD, Assistant ProfessorEpigenomics of immunological memory [Visit Allergy and Immunology]
Andrew Dauber, MD, Assistant ProfessorWe are interested in identifying novel genetic etiologies of severe human growth disorders. We use next generation sequencing of patient samples to identify genetic candidates and then explore the underlying functional biology in the lab. [Visit Endocrinology]
John Harley, MD, PhD, ProfessorWe work to bring the new technologies of genomics to clinical care. We do this for the institution as a service and for our own work in autoimmunity. At the moment we are evaluating the microbiome in blood for systemic lupus erythematosus. [Visit Rheumatology]
Rulang Jiang, PhD, ProfessorUnderstanding the genetic basis and molecular mechanisms of major birth defects [Visit the Jiang Lab]
Louis Muglia, MD, PhD, ProfessorGenetic and developmental mechanisms controlling the timing of birth and risk of preterm birth; molecular genetic analysis of the behavioral and neuroendocrine responses to stress. [Visit the Muglia Lab]
Joo-Seop Park, PhD, Assistant ProfessorGene regulatory networks underlying organogenesis and disease, Kidney development. [Visit Urology]
Rolf Stottmann, PhD, Assistant ProfessorMouse models of human congenital defects; development of the brain and face. [Visit the Stottmann Lab]
Chunyue Yin, PhD, Assistant ProfessorThe molecular and cellular mechanisms underlying liver development and disease pathogenesis using the zebrafish model organism. [Visit the Yin Lab]
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