Molecular and Developmental Biology Graduate Program

  • Genetics, Genomics & Bioinformatics

    Researchers in this area are trying to better understand questions of development, function, and pathophysiology.Many MDB laboratories use genetics and genomics in their research in a wide variety of ways. The power of next-generation sequencing techniques is often employed in either model systems or directly in clinical populations to gain insight into the mechanisms of development and disease. A major challenge in the current genomics age is to properly interpret these massive datasets and this is an active area of research in the field of bioinformatics.

    Faculty

    Bruce Aronow, PhD.Bruce Aronow, PhD, Professor
    Integrative bioinformatics and genomics relevant to human health and disease [Visit the Aronow / Jegga Lab]

    Artem Barski, PhD.Artem Barski, PhD, Assistant Professor
    Epigenomics of immunological memory [Visit Allergy and Immunology]

    Andrew Dauber, MD, Assistant Professor
    We are interested in identifying novel genetic etiologies of severe human growth disorders. We use next generation sequencing of patient samples to identify genetic candidates and then explore the underlying functional biology in the lab. [Visit Endocrinology]

    Lee Grimes, PhD.Lee Grimes, PhD, Professor
    Hematopoiesis, molecular biology, and molecular oncology including mouse modeling of hematopoiesis, myelopoiesis and leukemia. [Visit the Grimes Lab]

    John Harley, MD, PhD.John Harley, MD, PhD, Professor
    We work to bring the new technologies of genomics to clinical care. We do this for the institution as a service and for our own work in autoimmunity. At the moment we are evaluating the microbiome in blood for systemic lupus erythematosus. [Visit Rheumatology]

    Rulang Jiang, PhD.Rulang Jiang, PhD, Professor
    Understanding the genetic basis and molecular mechanisms of major birth defects [Visit the Jiang Lab]

    Kenneth Kaufman, PhD, Professor
    Utilization of next generation DNA sequencing data to identify variants that cause disease. We are particularly interested in autoimmune diseases such as systemic lupus erythematosus. [Visit CAGE]

    Rafi Kopan, PhD.Rafi Kopan, PhD, Professor
    The generation of different cell types and specialized organs. [Visit the Kopan Lab]

    Louis Muglia, MD, PhD.Louis Muglia, MD, PhD, Professor
    Genetic and developmental mechanisms controlling the timing of birth and risk of preterm birth; molecular genetic analysis of the behavioral and neuroendocrine responses to stress. [Visit the Muglia Lab]

    Joo-Seop Park, PhD.Joo-Seop Park, PhD, Assistant Professor
    Gene regulatory networks underlying organogenesis and disease, Kidney development. [Visit Urology]

    Rolf Stottmann, PhD.Rolf Stottmann, PhD, Assistant Professor
    Mouse models of human congenital defects; development of the brain and face. [Visit the Stottmann Lab]

    Chunyue Yin, PhD.Chunyue Yin, PhD, Assistant Professor
    The molecular and cellular mechanisms underlying liver development and disease pathogenesis using the zebrafish model organism. [Visit the Yin Lab]