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Mixed Connective Tissue Disease (MCTD)

Pediatric mixed connective tissue disease (MCTD) is a rare disease in children that has symptoms of arthritis along with features of scleroderma, dermatomyositis and lupus. It is characterized by lab tests showing the presence of specific antibodies to nuclear proteins (specifically, RNP).

MCTD is a type of autoimmune disease. The immune system primarily works to protect the body from infections. However, in autoimmune diseases, immune cells attack the body's own tissues, resulting in inflammation and tissue damage.

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Incidence of Pediatric MCTD

Causes of Pediatric MCTD

Signs and Symptoms of Pediatric MCTD

Diagnosis of Pediatric MCTD

Treatment of Pediatric MCTD

Long-Term Outlook for Children with MCTD

Last Updated: 07/2013