Neurocardiogenic syncope can often be treated without medications by avoiding situations that may provoke syncope, avoiding caffeine, increasing one's salt intake, and by staying well hydrated.
Fluid intake should be increased to the point that one's urine is colorless.
Various maneuvers can also be performed to prevent dizziness from progressing to syncope. These include lying down, squatting, tensing one's abdominal muscles, crossing one's legs at the ankles, and placing one foot on a stool or chair while the other foot remains on the ground.
It is uncommon to need medications for this problem. In the very few number of children and adolescents who need medications there are two main medications that are used. The most commonly prescribed medications for children with neurally mediated syncope are Florinef and midodrine. Florinef works by helping the kidneys retain fluid and sodium. Rare side effects include minimal weight gain, excessively high blood pressure, and leg cramping. Leg cramping is caused by low potassium. Patients on Florinef should increase their potassium intake by a well-balanced diet including adequate fruit (bananas) and vegetables. Midodrine works by constricting the blood vessels and directly raising the blood pressure. Side effects include high blood pressure.