Hogan Lab Research
Intestinal Immuno-Epithelial Interactions in Health and Disease
The goal of the Hogan laboratory is to understand the immune-intestinal epithelial interactions during homeostasis and how alterations in these pathways predispose to the development and maintenance of chronic inflammatory diseases such as food allergy and inflammatory bowel disease (IBD). In parallel with these mouse studies, we define the roles of leukocytes (monocyte / macrophages, mast cells and eosinophils) in intestinal inflammatory diseases by conducting studies of human monocyte / macrophages or by evaluating specimens derived from patients with food allergy and IBD.
