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Simon P. Hogan, PhD, director of research for the Division of Allergy and Immunology, was recognized for his dedicated efforts with the Mentoring Achievement Award in the Fourth Annual Faculty Awards by Cincinnati Children's.
Simon P. Hogan, PhD, was awarded a 2015 FARE Investigator in Food Allergy Award. This Mid-Career Investigator Award from Food Allergy Research & Education (FARE) will support Hogan in identifying the key proteins and cells that cause the blood vessel fluid leak leading to severe anaphylaxis triggered by foods.
Simon P. Hogan, PhD, was elected as a fellow in the Fellows of The Graduate School, an organization that recognizes distinguished researchers and scholars from throughout the University of Cincinnati. In addition to their outstanding individual accomplishments, fellows are generally among the most experienced and accomplished graduate-student mentors at the university.
Taeko Noah, PhD, has joined the Hogan Lab to work on a research project focused on the contribution of goblet cells to food antigen sensitization. Noah has extensive expertise and experience in intestinal goblet cell function and is a welcome addition to the division and Hogan Lab.
The goal of the Hogan Laboratory is to understand the immune-intestinal epithelial interactions during homeostasis and how alterations in these pathways predispose to the development and maintenance of chronic inflammatory diseases such as food allergy and anaphylaxis, infection-induced diarrheal diseases, cystic fibrosis (CF) and inflammatory bowel disease (IBD).
We take a multidisciplinary approach that integrates in vitro and in vivo models and cell and epithelial biology, transport physiology and mucosal immunology to 1) define fundamentals of epithelial barrier function; 2) understand the role of the epithelial barrier in regulating other mucosal processes, e.g. immune responses; 3) identify immune pathways that modulate epithelial barrier function and how these pathways alter susceptibility and severity to disease; and 4) develop novel approaches to correct barrier dysfunction and restore health.
Research opportunities with the Hogan Lab include graduate, postdoctoral and clinical fellowships. Our research is furthered by the excellence, dedication and collaborative outlook of our lab members.
This photomicrograph depicts the expression of the tight junction proteins claudin-3 and E-cadherin in the small intestine of mice and is part of the lab's ongoing research.
Simon P. Hogan, PhD
Associate ProfessorUC Department of Pediatrics
Member, Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center
Mailing Address:3333 Burnet AvenueMLC 7028Cincinnati, OH 45229
Phone: 513-636-6620Fax: 513-636-3310Email: email@example.com
Read more about the epithelial barrier.
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