Prasad Devarajan, MD
Title
Louise M. Williams Endowed Chair, Director of Nephrology and Hypertension
Appointment
Professor of Pediatrics and Developmental Biology
Email
prasad.devarajan@cchmc.org
Phone
513-636-4531
Fax
513-636-7407
Credentials
Premedical Studies: Bombay University, India, 1979
MD: Bombay University, India, 1985
Position History
1985-1986 Graduate Research, Dept of Physiology (Laboratory of Leon C. Moore, Ph.D.), SUNY Stony Brook, NY
1986-1989 Internship and Residency, Dept of Pediatrics, SUNY Stony Brook, NY
1989-1991 NIH Fellow, Pediatric Scientist Development Program, Hematology / Genetics, (Laboratory of Edward J. Benz, Jr., MD), Yale University School of Medicine, New Haven, Conn.
1991-1993 Postdoctoral Fellowship, Dept. of Pediatrics, Division of Nephrology, Yale University School of Medicine, New Haven, Conn.
1993-1995 Research Associate, Dept of Pathology and Cell Biology (Laboratory of Jon S. Morrow, MD, PhD), Yale University School of Medicine, New Haven, Conn.
1993-1994 Instructor, Dept of Pediatrics, Division of Nephrology, Yale University School of Medicine, New Haven, Conn.
1994-1998 Assistant Professor, Dept of Pediatrics, Division of Nephrology, Yale University School of Medicine, New Haven, Conn.
1998-1999 Assistant Professor & Director of Research, Dept of Pediatrics, Division of Nephrology, Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY
1999-2002 Associate Professor and Director of Research, Dept. of Pediatrics, Division of Nephrology, Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY
July 2002 Williams Professor of Pediatrics and Developmental Biology, Director of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio.
Awards and Honors
Best Doctors in America, 2008
Awarded "2005 Best Doctors"
1988-present Reviewer:
New England Journal of Medicine
Lancet
Journal of Cell Biology,
Journal of Biological Chemistry,
Pediatrics,
Journal of Pediatrics,
American Journal of Physiology,
Journal of American Society of Nephrology,
Pediatric Nephrology,
Kidney International,
Transplantation,
American Journal of Transplantation,
American Journal of Kidney Disease
1992-present Member, SPR, ASPN, ASN, NKF, AHA Council on Kidney in Cardiovascular Disease
2000-present External Reviewer, NIH/NIDDK, Special Emphasis Review Panels
2001-present Ad Hoc Reviewer, NIH/NIDDK, Study Sections
2001-present Associate Editor, American Journal of Physiology (Cell Physiology)
2002-present Member, American Society for Pediatric Nephrology Research Council
2003-present Associate Editor, Pediatric Nephrology
2004-present ASPN representative, Acute Kidney Injury Network
2005-present Member, Acute Renal Failure Advisory Committee, ASN
Research Grants and Contracts
T32DK007695 Devarajan (PI) 07/01/07-06/30/12
NIH
Research Training in Pediatric Nephrology
Translational Research Devarajan (PI) 07/01/08-06/30/09
Children's Hospital Medical Center
A Novel Urinary Biomarker Panel For Lupus
Nephritis
DK RO1 DK069749 Devarajan
(PI) 04/01/05-03/31/10
NIH/NID
Implications of the ASK1/JNK pathway in ARF
This proposal examines the role of ASK1/JNK signal
transduction pathway in acute renal failure
W81XWH0710322 Devarajan (PI) 06/01/07-05/31/10
Department of Defense
Early Prediction Of Lupus Nephritis Using Advanced Proteomics
The objective is to identify and subsequently develop high-quality biomarkers of SLE for use in clinical practice and research.
Publications, Most Recent
Prasad Devarajan's publications as listed by PubMed
Mori K, Lee HT, Rapoport D, Drexler I, Foster K, Yang J,
Schmidt-Ott, Chen X, Li JY, Weiss S, Mishra J, Cheema FH, Markowitz G, Suganami
T, Sawai K, Mukoyama M, Kunis C, D’Agati V, Devarajan P, Barasch J. Endocytic delivery of
lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion
injury. J Clin Invest 115:610–621, 2005
Mishra J, Dent C, Tarabishi R, Mitsnefes MM, Ma Q, Kelly C,
Ruff SM, Zahedi K, Shao M, Bean J, Mori K, Barasch J, Devarajan P. Neutrophil gelatinase-associated lipocalin
(NGAL) as a biomarker for acute renal injury following cardiac surgery. Lancet 365:1231-1238, 2005
Nguyen M, Ross G, Dent C, Devarajan P. Early prediction of acute renal injury using
urinary proteomics. Am J Nephrol, 25:318-326,
2005
Tarabishi R, Zahedi K, Mishra J, Ma Q, Devarajan P. Induction of Zf9 in the kidney following
early ischemia-reperfusion. Kidney
International, 68:1511-1519, 2005
Devarajan P. Update
on mechanisms of ischemic acute kidney injury.
J Am Soc Nephrol 17:1503-1520, 2006
Parikh CR, Jani A, Mishra J, Ma Q, Kelly C, Barasch J,
Edelstein CL, Devarajan P. Urine NGAL
and IL-18 are predictive biomarkers for DGF following kidney transplantation. Am J Transplant 6:1639-1645, 2006
Parikh CR, Mishra J, Thiessen-Philbrook H, Dursun B, Ma Q,
Kelly C, Dent C, Devarajan P, Edelstein CL. Urinary IL-18 is an early
predictive biomarker of acute kidney injury after cardiac surgery. Kidney Int 70:199-203, 2006
Brunner HI, Mueller M, Rutherford C, Passo MH, Witte D, Grom
A, Mishra J, Devarajan P. Urinary NGAL
as a biomarker of nephritis in childhood-onset SLE. Arthritis and Rheumatism 54:2577-2584, 2006
Mitsnefes M, Kathman T, Mishra J, Kartal J, Khoury P,
Nickolas T, Barasch J, Devarajan P. Serum
NGAL as a marker of renal function in children with chronic kidney
disease. Pediatr Nephrol 22:101-108,
2007
Devarajan P. Proteomics
for biomarker discovery in acute kidney injury.
Semin Nephrol, 27:637-651, 2007
Hirsch R, Dent C, Pfriem H, Allen J, Beekman RH, Ma Q,
Bennett M, Mitsnefes M, Devarajan P.
NGAL is an early predictive biomarker of contrast-induced nephropathy in
children. Pediatr Nephrol, 22:2089-2095,
2007
Dent CL, Ma Q, Dastrala
S, Bennett M, Mitsnefes MM, Barasch J, Devarajan P. Plasma NGAL predicts acute kidney
injury, morbidity and mortality after pediatric cardiac surgery: a prospective
uncontrolled cohort study. Crit Care
11(6):R127, 2007
Devarajan P, Parikh
C, Barasch J. Case 31-2007: a man
with abdominal pain and elevated creatinine.
N Engl J Med. 358(3):312, 2008
Portilla D, Dent C, Sugaya T, Nagothu KK, Kundi I, Moore P, Noiri E, Devarajan
P. Liver fatty acid-binding protein as a
biomarker of acute kidney injury after cardiac surgery. Kidney Int. 73(4):465-72, 2008
Devarajan P. Proteomics for the investigation of acute
kidney injury. Contrib Nephrol 160:1-16,
2008
Bennett M, Dent CL, Ma Q, Dastrala S, Grenier F, Workman R,
Syed H, Ali S, Barasch J, Devarajan P.
Urine NGAL Predicts Severity of Acute Kidney Injury After Cardiac
Surgery: A Prospective Study. Clin J Am
Soc Nephrol 3(3):665-673, 2008
Related Areas
This person works in these other areas at Cincinnati Children's Hospital Medical Center:
