A photo of Stuart L. Goldstein.

Stuart L. Goldstein, MD, FAAP, FNKF

  • Clark D. West Endowed Chair
  • Director, Center for Acute Care Nephrology 
  • Medical Director, Pheresis Service
  • Co-Director, Heart Institute Research Core
  • Professor, UC Department of Pediatrics
Nephrology also allows me to practice across the entire spectrum of pediatric illness, from acute critical care, to chronic care and outpatient care.



As a pediatric kidney specialist, I treat children and adolescents in all areas of pediatric nephrology. These include general nephrology, acute kidney injury (AKI), dialysis, transplantation and tuberous sclerosis. I also consult on fetal care if there is a problem with the unborn baby’s kidneys.

I was drawn to the field of nephrology by the opportunity it presents to improve the outcomes for children with kidney problems. Working with children and their families, I help patients reach their full potential. Nephrology also allows me to practice across the entire spectrum of pediatric illness, from acute critical care, to chronic care and outpatient care.

My research is focused on short- and long-term outcomes for children who have AKI and those who are at risk for AKI. I’m interested in AKI epidemiology and outcomes, acute renal replacement therapy and investigation of novel urinary AKI biomarkers in the pediatric population.

In 2012, I established Prospective Pediatric AKI Research Group (ppAKI-RG). The ppAKI-RG is comprised of more than 60 centers around the world with the goal of improving outcomes for the child with, or at-risk for, AKI. This consortium focuses on multicentered research studies that are dedicated to understanding and treating AKI in pediatric patients. This group has completed three major, unprecedented national and international studies to accurately characterize pediatric AKI epidemiology, reduce AKI and improve patient outcomes.

I also developed the only pediatric-specific, acute-care nephrology subspecialty fellowship with graduates who are now leaders in the field of pediatric AKI.

MD: Columbia College of Physicians and Surgeons, New York, NY, 1990.

Residency: Baylor College of Medicine, Houston, TX.

Fellowship: Pediatric Nephrology, Children's Hospital, Boston, MA.


Acute kidney injury; continuous renal replacement therapy; cardio-renal syndrome; nephrotoxic medication associated morbidity

Services and Specialties

Nephrology and Hypertension, Dialysis, End-Stage Renal Disease, Tuberous Sclerosis, Nephrology - Acute Care, Heart, Colorectal Disorders, Fontan Management


Acute kidney injury epidemiology and biomarkers; heart failure associated chronic kidney disease; nephrotoxic medication associated acute kidney injury reduction

Research Areas

Cardiology, Nephrology and Hypertension, Heart

Additional Languages


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Serum renin and prorenin concentrations predict severe persistent acute kidney injury and mortality in pediatric septic shock. Stanski, NL; Shakked, NP; Zhang, B; Cvijanovich, NZ; Fitzgerald, JC; Jain, PN; Schwarz, AJ; Nowak, J; Weiss, SL; Allen, GL; et al. Pediatric Nephrology. 2023.

Use of extracorporeal immunomodulation in a toddler with hemophagocytic lymphohistiocytosis and multisystem organ failure. Goldstein, SL; Yessayan, LT; Krallman, KA; Collins, M; Benoit, S; Westover, A; Humes, HD. Pediatric Nephrology. 2023; 38:927-931.

Urine Complement Factor Ba Is Associated with AKI in Critically Ill Children. Stenson, EK; Edelstein, CL; You, Z; Miyazaki-Anzai, S; Thurman, JM; Dixon, BP; Zappitelli, M; Goldstein, SL; Akcan Arikan, A; Kendrick, J. 2023; 4:326-332.

Hypernatremia Correction in Children: Maybe Slow but Steady Does Not Win the Race?. Goldstein, SL. Clinical journal of the American Society of Nephrology : CJASN. 2023; 18:292-293.

WCN23-0514 Long-term kidney outcomes following pediatric acute kidney injury not receiving dialysis: A population-based propensity-matched cohort study. Robinson, C; Jeyakumar, N; Luo, B; Askenazi, D; Garg, A; Goldstein, S; Greenberg, J; Mammen, C; Nash, D; Parekh, R; et al. Kidney International Reports. 2023; 8:s8-s9.

Impact of the Magnitude and Timing of Fluid Overload on Outcomes in Critically Ill Children: A Report From the Multicenter International Assessment of Worldwide Acute Kidney Injury, Renal Angina, and Epidemiology (AWARE) Study. Selewski, DT; Gist, KM; Basu, RK; Goldstein, SL; Zappitelli, M; Soranno, DE; Mammen, C; Sutherland, SM; Askenazi, DJ; Ricci, Z; et al. Critical Care Medicine. 2023.

Premature infants born <28 weeks with acute kidney injury have increased bronchopulmonary dysplasia rates. Starr, MC; Schmicker, RH; Halloran, BA; Heagerty, P; Brophy, P; Goldstein, SL; Juul, SE; Hingorani, S; Askenazi, DJ. Pediatric Research. 2023.

Relationship between piperacillin concentrations, clinical factors and piperacillin/tazobactam-associated acute kidney injury. Tang Girdwood, S; Hasson, D; Caldwell, JT; Slagle, C; Dong, S; Fei, L; Tang, P; Vinks, AA; Kaplan, J; Goldstein, SL. Journal of Antimicrobial Chemotherapy. 2023; 78:478-487.

Nephrotoxin Exposure and Acute Kidney Injury in Adults. Griffin, BR; Wendt, L; Vaughan-Sarrazin, M; Hounkponou, H; Reisinger, HS; Goldstein, SL; Jalal, D; Misurac, J. Clinical journal of the American Society of Nephrology : CJASN. 2023; 18:163-172.

First-Time Use of the Seraph® 100 Microbind® Affinity Blood Filter in an Adolescent Patient with Severe COVID-19 Disease: A Case Report. Merrill, KA; Krallman, KA; Loeb, D; Standage, SW; Mattoon, D; Shan, D; Goldstein, SL; Schuh, MP. Case Reports in Nephrology and Dialysis. 2023; 13:1-6.

From the Blog

Better AWAREness of Acute Kidney Injury Could Transform Intensive Care
Emergency and Critical Care

Better AWAREness of Acute Kidney Injury Could Transform Intensive Care

Stuart L. Goldstein, MD, FAAP, FNKF6/30/2019

7 Things Parents Need To Know About Nephrotoxic Medications
Blog Rare and Complex Conditions

7 Things Parents Need To Know About Nephrotoxic Medications

By Stuart Goldstein, MD3/10/2016

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