Stuart L. Goldstein, MD, has been an active investigator in the field of pediatric acute kidney injury (AKI) since 2000. Dr. Goldstein’s main research foci include: AKI epidemiology and outcomes, acute renal replacement therapy provision and investigation of novel urinary AKI biomarkers in the pediatric population. Dr. Goldstein has established a strong record of interdisciplinary and inter-institutional collaboration with cardiologists, intensivists and emergency center physicians, which is evidenced by his establishment and directing of the Prospective Pediatric Continuous Renal Replacement Therapy Registry from 2001 to 2012, and the Prospective Pediatric AKI Research Group (ppAKI-RG) in 2012. The ppAKI-RG is comprised of 52 centers from around the world with the goal of improving outcomes for the child with or at-risk for, AKI.
Dr. Goldstein has led efforts to develop a standardized definition for pediatric AKI, assess novel AKI biomarkers in heterogeneous populations, and conceiving and validating stratification tools to identify patients at risk for AKI. Building upon these findings, Dr. Goldstein embarked on establishing the ppAKI-RG consortium to focus on multi-centered research studies that are dedicated to understanding and treating AKI in pediatric patients. Currently, the ppAKI-RG has completed three major, and unprecedented, national and international studies (AWARE, NINJA and DIRECT) to accurately characterize pediatric AKI epidemiology, reduce AKI and improve patient outcomes. Dr. Goldstein is also a recognized educator; he and his team host the CRRT University™ course, which provides an high-fidelity simulation experience to pediatric and adult CRRT programs from around the country with a faculty of world renowned experts in AKI. In addition he has developed the only pediatric specific acute care nephrology sub-specialty fellowship with graduates who are now leaders in the field of pediatric AKI.
Acute kidney injury; continuous renal replacement therapy; cardio-renal syndrome; nephrotoxic medication associated morbidity
Acute kidney injury epidemiology and biomarkers; heart failure associated chronic kidney disease; nephrotoxic medication associated acute kidney injury reduction
Professor, UC Department of Pediatrics
Nephrology and Hypertension, Cardiology, Nephrology and Hypertension, Kidney Transplant Program, Dialysis Unit, End Stage Renal Disease, Tuberous Sclerosis, Heart Institute, Center for Acute Care Nephrology CACN, Heart Institute, Best Doctors 2017-18, Colorectal Center, Fontan Management Clinic