A photo of Stuart L. Goldstein.

Stuart L. Goldstein, MD, FAAP, FNKF

  • Clark D. West Endowed Chair
  • Director, Center for Acute Care Nephrology 
  • Medical Director, Pheresis Service
  • Co-Director, Heart Institute Research Core
  • Professor, UC Department of Pediatrics
Nephrology also allows me to practice across the entire spectrum of pediatric illness, from acute critical care, to chronic care and outpatient care.



As a pediatric kidney specialist, I treat children and adolescents in all areas of pediatric nephrology. These include general nephrology, acute kidney injury (AKI), dialysis, transplantation and tuberous sclerosis. I also consult on fetal care if there is a problem with the unborn baby’s kidneys.

I was drawn to the field of nephrology by the opportunity it presents to improve the outcomes for children with kidney problems. Working with children and their families, I help patients reach their full potential. Nephrology also allows me to practice across the entire spectrum of pediatric illness, from acute critical care, to chronic care and outpatient care.

My research is focused on short- and long-term outcomes for children who have AKI and those who are at risk for AKI. I’m interested in AKI epidemiology and outcomes, acute renal replacement therapy and investigation of novel urinary AKI biomarkers in the pediatric population.

In 2012, I established Prospective Pediatric AKI Research Group (ppAKI-RG). The ppAKI-RG is comprised of more than 60 centers around the world with the goal of improving outcomes for the child with, or at-risk for, AKI. This consortium focuses on multicentered research studies that are dedicated to understanding and treating AKI in pediatric patients. This group has completed three major, unprecedented national and international studies to accurately characterize pediatric AKI epidemiology, reduce AKI and improve patient outcomes.

I also developed the only pediatric-specific, acute-care nephrology subspecialty fellowship with graduates who are now leaders in the field of pediatric AKI.

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Immunomodulatory therapy using a pediatric dialysis system ameliorates septic shock in miniature pigs. Johnston, KA; Pino, CJ; Chan, G; Ketteler, SK; Goldstein, SL; Humes, HD. Pediatric Research. 2022.

Commentary: "PCRRT Expert Committee ICONIC Position Paper on Prescribing Kidney Replacement Therapy in Critically Sick Children With Acute Liver Failure ". Deep, A; Alexander, EC; Ricci, Z; Grazioli, S; Ronco, C; Goldstein, S; Akcan-Arikan, A. Frontiers in Pediatrics. 2022; 10.

Assessment of a modified renal angina index for AKI prediction in critically ill adults. Ortiz-Soriano, V; Kabir, S; Claure-Del Granado, R; Stromberg, A; Toto, RD; Moe, OW; Goldstein, SL; Neyra, JA. Nephrology Dialysis Transplantation. 2022; 37:895-903.

Under-Recognition of Neonatal Acute Kidney Injury and Lack of Follow-Up. Roy, J; Goldstein, SL; Schuh, MP. American Journal of Perinatology. 2022; 39:526-531.

Comparison of nafamostat mesilate to citrate anticoagulation in pediatric continuous kidney replacement therapy. Miyaji, MJ; Ide, K; Takashima, K; Maeno, M; Krallman, KA; Lazear, D; Goldstein, SL. Pediatric Nephrology. 2022.

Long-Term Healthcare Cost Savings of a Pediatric Nephrotoxic Medication-Associated Acute Kidney Injury Reduction Program in a Simulated Sample. Dynan, L; Lazear, D; Goldstein, SL. Journal of Pharmacy Practice. 2022.

Modifying the Renal Angina Index for Predicting AKI and Related Adverse Outcomes in Pediatric Heart Surgery. Gist, KM; SooHoo, M; Mack, E; Ricci, Z; Kwiatkowski, DM; Cooper, DS; Krawczeski, CD; Alten, JA; Goldstein, SL; Basu, RK. World journal for pediatric & congenital heart surgery. 2022; 13:196-202.

Survival of infants treated with CKRT: comparing adapted adult platforms with the Carpediem™. Goldstein, SL; Vidal, E; Ricci, Z; Paglialonga, F; Peruzzi, L; Giordano, M; Laforgia, N; Ronco, C. Pediatric Nephrology. 2022; 37:667-675.

Fluid Homeostasis and Diuretic Therapy in the Neonate. Slagle, C; Gist, KM; Starr, MC; Hemmelgarn, TS; Goldstein, SL; Kent, AL. NeoReviews. 2022; 23:e189-e204.

Artificial Intelligence for AKI!Now: Let's Not Await Plato's Utopian Republic. Soranno, DE; Bihorac, A; Goldstein, SL; Kashani, KB; Menon, S; Nadkarni, GN; Neyra, JA; Pannu, NI; Singh, K; Cerda, J; et al. 2022; 3:376-381.

From the Blog

Better AWAREness of Acute Kidney Injury Could Transform Intensive Care
Emergency and Critical Care

Better AWAREness of Acute Kidney Injury Could Transform Intensive Care

Stuart L. Goldstein, MD, FAAP, FNKF6/30/2019

7 Things Parents Need To Know About Nephrotoxic Medications
BlogRare and Complex Conditions

7 Things Parents Need To Know About Nephrotoxic Medications

By Stuart Goldstein, MD3/10/2016

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