A photo of Stuart L. Goldstein.

Stuart L. Goldstein, MD, FAAP, FNKF

  • Clark D. West Endowed Chair
  • Director, Center for Acute Care Nephrology 
  • Medical Director, Pheresis Service
  • Co-Director, Heart Institute Research Core
  • Professor, UC Department of Pediatrics
Nephrology also allows me to practice across the entire spectrum of pediatric illness, from acute critical care, to chronic care and outpatient care.



As a pediatric kidney specialist, I treat children and adolescents in all areas of pediatric nephrology. These include general nephrology, acute kidney injury (AKI), dialysis, transplantation and tuberous sclerosis. I also consult on fetal care if there is a problem with the unborn baby’s kidneys.

I was drawn to the field of nephrology by the opportunity it presents to improve the outcomes for children with kidney problems. Working with children and their families, I help patients reach their full potential. Nephrology also allows me to practice across the entire spectrum of pediatric illness, from acute critical care, to chronic care and outpatient care.

My research is focused on short- and long-term outcomes for children who have AKI and those who are at risk for AKI. I’m interested in AKI epidemiology and outcomes, acute renal replacement therapy and investigation of novel urinary AKI biomarkers in the pediatric population.

In 2012, I established Prospective Pediatric AKI Research Group (ppAKI-RG). The ppAKI-RG is comprised of more than 60 centers around the world with the goal of improving outcomes for the child with, or at-risk for, AKI. This consortium focuses on multicentered research studies that are dedicated to understanding and treating AKI in pediatric patients. This group has completed three major, unprecedented national and international studies to accurately characterize pediatric AKI epidemiology, reduce AKI and improve patient outcomes.

I also developed the only pediatric-specific, acute-care nephrology subspecialty fellowship with graduates who are now leaders in the field of pediatric AKI.

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Consensus-Based Recommendations on Priority Activities to Address Acute Kidney Injury in Children: A Modified Delphi Consensus Statement. Goldstein, SL; Akcan-Arikan, A; Alobaidi, R; Askenazi, DJ; Bagshaw, SM; Barhight, M; Barreto, E; Bayrakci, B; Bignall, ON R; Bjornstad, E; et al. JAMA Network Open. 2022; 5.

Olfactomedin 4 as a novel loop of Henle-specific acute kidney injury biomarker. Hasson, DC; Krallman, K; VanDenHeuvel, K; Menon, S; Piraino, G; Devarajan, P; Goldstein, SL; Alder, M. Physiological Reports. 2022; 10.

Evaluation and Management of Acute Kidney Injury in Children. Zappitelli, M; Goldstein, SL; Ricci, Z. Pediatric Nephrology. 2022.

Choline supplementation attenuates experimental sepsis-associated acute kidney injury. Hasson, DC; Watanabe-Chailland, M; Romick-Rosendale, L; Koterba, A; Miner, DS; Lahni, P; Ma, Q; Goldstein, SL; Devarajan, P; Standage, SW. American Journal of Physiology - Renal Physiology. 2022; 323:F255-F271.

Assessment of prescribed vs. achieved fluid balance during continuous renal replacement therapy and mortality outcome. Neyra, JA; Lambert, J; Ortiz-Soriano, V; Cleland, D; Colquitt, J; Adams, P; Bissell, BD; Chan, L; Nadkarni, GN; Tolwani, A; et al. PLoS ONE. 2022; 17.

Long-term Health Care Utilization and Associated Costs After Dialysis-Treated Acute Kidney Injury in Children. Robinson, CH; Klowak, JA; Jeyakumar, N; Luo, B; Wald, R; Garg, AX; Nash, DM; McArthur, E; Greenberg, JH; Askenazi, D; et al. American Journal of Kidney Diseases. 2022.

A risk-stratified assessment of biomarker-based acute kidney injury phenotypes in children. Stanski, NL; Krallman, KA; Chima, RS; Goldstein, SL. Pediatric Research. 2022.

Integration of the Renal Angina Index and Urine Neutrophil Gelatinase-Associated Lipocalin Improves Severe Acute Kidney Injury Prediction in Critically Ill Children and Young Adults. Goldstein, SL; Krallman, KA; Kirby, C; Roy, JP; Collins, M; Fox, K; Schmerge, A; Wilder, S; Gerhardt, B; Chima, R; et al. Kidney International Reports. 2022; 7:1842-1849.

Prevalence and Risk Factors for Kidney Disease and Elevated BP in 2-Year-Old Children Born Extremely Premature. Hingorani, S; Schmicker, R; Ahmad, KA; Frantz, ID; Mayock, DE; Gamma, EF L; Baserga, M; Khan, JY; Gilmore, MM; Robinson, T; et al. Clinical journal of the American Society of Nephrology : CJASN. 2022.

Urine acute kidney injury biomarkers in extremely low gestational age neonates: a nested case control study of 21 candidate urine biomarkers. Askenazi, DJ; Halloran, BA; Heagerty, PJ; Schmicker, RH; Juul, SE; Hingorani, S; Goldstein, SL. Pediatric Nephrology. 2022.

From the Blog

Better AWAREness of Acute Kidney Injury Could Transform Intensive Care
Emergency and Critical Care

Better AWAREness of Acute Kidney Injury Could Transform Intensive Care

Stuart L. Goldstein, MD, FAAP, FNKF6/30/2019

7 Things Parents Need To Know About Nephrotoxic Medications
BlogRare and Complex Conditions

7 Things Parents Need To Know About Nephrotoxic Medications

By Stuart Goldstein, MD3/10/2016

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