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A photo of Stuart L. Goldstein.

Clark D. West Endowed Chair

Director, Center for Acute Care Nephrology 

Medical Director, Pheresis Service

Co-Director, Heart Institute Research Core

Professor, UC Department of Pediatrics



Board Certified

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My Biography & Research


Stuart L. Goldstein, MD, has been an active investigator in the field of pediatric acute kidney injury (AKI) since 2000. Dr. Goldstein’s main research foci include: AKI epidemiology and outcomes, acute renal replacement therapy provision and investigation of novel urinary AKI biomarkers in the pediatric population. Dr. Goldstein has established a strong record of interdisciplinary and inter-institutional collaboration with cardiologists, intensivists and emergency center physicians, which is evidenced by his establishment and directing of the Prospective Pediatric Continuous Renal Replacement Therapy Registry from 2001 to 2012, and the Prospective Pediatric AKI Research Group (ppAKI-RG) in 2012. The ppAKI-RG is comprised of 52 centers from around the world with the goal of improving outcomes for the child with or at-risk for, AKI.

Dr. Goldstein has led efforts to develop a standardized definition for pediatric AKI, assess novel AKI biomarkers in heterogeneous populations, and conceiving and validating stratification tools to identify patients at risk for AKI. Building upon these findings, Dr. Goldstein embarked on establishing the ppAKI-RG consortium to focus on multi-centered research studies that are dedicated to understanding and treating AKI in pediatric patients. Currently, the ppAKI-RG has completed three major, and unprecedented, national and international studies (AWARE, NINJA and DIRECT) to accurately characterize pediatric AKI epidemiology, reduce AKI and improve patient outcomes. Dr. Goldstein is also a recognized educator; he and his team host the CRRT University™ course, which provides an high-fidelity simulation experience to pediatric and adult CRRT programs from around the country with a faculty of world renowned experts in AKI. In addition he has developed the only pediatric specific acute care nephrology sub-specialty fellowship with graduates who are now leaders in the field of pediatric AKI.

Additional Languages


Clinical Interests

Acute kidney injury; continuous renal replacement therapy; cardio-renal syndrome; nephrotoxic medication associated morbidity

Research Interests

Acute kidney injury epidemiology and biomarkers; heart failure associated chronic kidney disease; nephrotoxic medication associated acute kidney injury reduction

Academic Affiliation

Professor, UC Department of Pediatrics


Nephrology and Hypertension, Kidney Transplant, Dialysis, End-Stage Renal Disease, Tuberous Sclerosis, Nephrology - Acute Care, Heart, Colorectal Disorders, Fontan Management, Cardiology, Nephrology and Hypertension, Heart

Cincinnati Children's Blog

7 Things Parents Need To Know About Nephrotoxic Medications

BlogRare and Complex Conditions

7 Things Parents Need To Know About Nephrotoxic Medications

By Stuart Goldstein, MD3/10/2016

Science Blog

Better AWAREness of Acute Kidney Injury Could Transform Intensive Care

Better AWAREness of Acute Kidney Injury Could Transform Intensive Care

Stuart L. Goldstein, MD, FAAP, FNKF6/30/2019

My Locations

My Education

MD: Columbia College of Physicians and Surgeons, New York, NY, 1990.

Residency: Baylor College of Medicine, Houston, TX.

Fellowship: Pediatric Nephrology, Children's Hospital, Boston, MA.

My Publications

Process based quality improvement using a continuous renal replacement therapy dashboard. Mottes, TA; Goldstein, SL; Basu, RK. BMC Nephrology. 2019; 20.

Baby NINJA (Nephrotoxic Injury Negated by Just-in-Time Action): Reduction of Nephrotoxic Medication-Associated Acute Kidney Injury in the Neonatal Intensive Care Unit. Stoops, C; Stone, S; Evans, E; Dill, L; Henderson, T; Griffin, R; Goldstein, SL; Coghill, C; Askenazi, DJ. The Journal of Pediatrics. 2019; 215:223-228.e6.

Evidence-based development of a nephrotoxic medication list to screen for acute kidney injury risk in hospitalized children. Goswami, E; Ogden, RK; Bennett, WE; Goldstein, SL; Hackbarth, R; Somers, MJ G; Yonekawa, K; Misurac, J. American Journal of Health-System Pharmacy. 2019; 76:1869-1874.

Kidney support in children using an ultrafiltration device: A multicenter, retrospective study. Menon, S; Broderick, J; Munshi, R; Dill, L; Depaoli, B; Fathallah-Shaykh, S; Claes, D; Goldstein, SL; Askenazi, DJ. Clinical journal of the American Society of Nephrology : CJASN. 2019; 14:1432-1440.

Integration of urinary neutrophil gelatinase-associated lipocalin with serum creatinine delineates acute kidney injury phenotypes in critically ill children. Stanski, N; Menon, S; Goldstein, SL; Basu, RK. Journal of Critical Care. 2019; 53:1-7.

Use of height-independent baseline creatinine imputation method with renal angina index. Roy, JP; Johnson, C; Towne, B; Menke, F; Kiger, S; Young, W; Basu, R; Chima, R; Fei, L; Krallman, K; et al. Pediatric Nephrology. 2019; 34:1777-1784.

Secular Trends in Incidence, Modality and Mortality with Dialysis Receiving AKI in Children in Ontario: A Population-Based Cohort Study. Chanchlani, R; Nash, DM; McArthur, E; Zappitelli, M; Archer, V; Kuwornu, JP; Garg, AX; Greenberg, JH; Goldstein, SL; Thabane, L; et al. Clinical journal of the American Society of Nephrology : CJASN. 2019; 14:1288-1296.

A novel strategy for identifying early acute kidney injury in pediatric hematopoietic stem cell transplantation. Benoit, SW; Dixon, BP; Goldstein, SL; Bennett, MR; Lane, A; Lounder, DT; Rotz, SJ; Gloude, NJ; Lake, KE; Litts, B; et al. Bone Marrow Transplantation. 2019; 54:1453-1461.

Reduction in Nephrotoxic Antimicrobial Exposure Decreases Associated Acute Kidney Injury in Pediatric Hematopoietic Stem Cell Transplant Patients. Benoit, SW; Goldstein, SL; Dahale, DS; Haslam, DB; Nelson, A; Truono, K; Davies, SM. Biology of Blood and Marrow Transplantation. 2019; 25:1654-1658.

Identifying Important Outcomes for Young People With CKD and Their Caregivers: A Nominal Group Technique Study. Hanson, CS; Gutman, T; Craig, JC; Bernays, S; Raman, G; Zhang, Y; James, LJ; Ralph, AF; Ju, A; Manera, KE; et al. American Journal of Kidney Diseases. 2019; 74:82-94.