A photo of Hermine Brunner.

Director, Division of Rheumatology

Professor, UC Department of Pediatrics



Board Certified

My Biography & Research


Hermine Brunner, MD, MSc, MBA, is a pediatric rheumatologist with a special clinical and research interest in pediatric lupus. Her research is focused on biomarker discovery and the testing of new medications for lupus. She is also involved in trial design and provides statistical support at Cincinnati Children's. As head of the Lupus Center, she is involved in the conduction of the Lupus Clinic and the organization of Lupus Support Groups. She also pioneers the development of outcome measures and improving the quality of clinical of children with lupus and other rheumatic diseases.

Additional Languages

German, Portuguese

Clinical Interests

Health-related quality of life; outcome research; lupus

Research Interests

Economic analyses; HRQOL; measurement development; outcome research; lupus

Academic Affiliation

Professor, UC Department of Pediatrics


Rheumatology, Lupus, Rheumatology, Global Health

My Locations

My Education

MD: Ludwig Maximilan University, Munich, Germany, 1991.

Residency: University of Chicago, 1997.

Fellowship: University of Toronto & Cincinnati, 1999.

MSc: Clinical Epidemiology: University of Toronto, 1999.

Certification: Pediatrics 1997; Rheumatology, 2002.

My Publications

Neutropenia During Tocilizumab Treatment Is Not Associated with Infection Risk in Systemic or Polyarticular-course Juvenile Idiopathic Arthritis. Pardeo, M; Wang, J; Ruperto, N; Alexeeva, E; Chasnyk, V; Schneider, R; Horneff, G; Huppertz, H; Minden, K; Onel, K; et al. The Journal of rheumatology. 2019; 46:1117-1126.

Update on the treatment and outcome of systemic lupus erythematous in children. Rodriguez-Smith, J; Brunner, HI. Current Opinion in Rheumatology. 2019; 31:464-470.

Establishing an Updated Core Domain Set for Studies in Juvenile Idiopathic Arthritis: A Report from the OMERACT 2018 JIA Workshop. Morgan, EM; Munro, JE; Horonjeff, J; Horgan, B; Shea, B; Feldman, BM; Clairman, H; III, BC O; Thornhill, S; Strand, V; et al. The Journal of rheumatology. 2019; 46:1006-1013.

Elevated serum complement levels and higher gene copy number of complement C4B are associated with hypertension and effective response to statin therapy in childhood-onset systemic lupus erythematosus (SLE). Mulvihill, E; Ardoin, S; Thompson, SD; Zhou, B; Yu, GR; King, E; Singer, N; Levy, DM; Brunner, H; Wu, YL; et al. Lupus Science and Medicine. 2019; 6.

American College of Rheumatology Provisional Criteria for Clinically Relevant Improvement in Children and Adolescents With Childhood-Onset Systemic Lupus Erythematosus. Brunner, HI; Holland, MJ; Beresford, MW; Ardoin, SP; Appenzeller, S; Silva, CA; Flores, F; Aydin, PO A; Wenderfer, SE; Levy, DM; et al. Arthritis Care and Research. 2019; 71:579-590.

Proteomic profiling of urine: implications for lupus nephritis. Aljaberi, N; Bennett, M; Brunner, HI; Devarajan, P. Expert Review of Proteomics. 2019; 16:303-313.

Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans for Juvenile Idiopathic Arthritis-Associated and Idiopathic Chronic Anterior Uveitis. Angeles-Han, ST; Lo, MS; Henderson, LA; Lerman, MA; Abramson, L; Coopers, AM; Parsa, MF; Zemel, LS; Ronis, T; Beukelman, T; et al. Arthritis Care and Research. 2019; 71:482-491.

Serum S100A8/A9 and S100A12 Levels in Children With Polyarticular Forms of Juvenile Idiopathic Arthritis: Relationship to Maintenance of Clinically Inactive Disease During Anti-Tumor Necrosis Factor Therapy and Occurrence of Disease Flare After Discontinuation of Therapy. Hinze, CH; Foell, D; Johnson, AL; Spalding, SJ; Gottlieb, BS; Morris, PW; Kimura, Y; Onel, K; Li, SC; Grom, AA; et al. Arthritis and Rheumatology. 2019; 71:451-459.

Therapeutic Targeting of Follicular Helper T Cells with Chimeric Antigen Receptor-Expressing Natural Killer Cells. Reighard, SD; Cranert, SA; Rangel, KM; Ali, A; Cruz-Lynch, AT D L; Tuazon, JA; Kottyan, LC; Smith, DF; Brunner, HI; Waggoner, S. 2019.

Development and pilot testing of the treatment and education approach for childhood-onset lupus (TEACH): a cognitive behavioral treatment. Cunningham, NR; Fussner, LM; Moorman, E; Aydin, PO A; Brunner, HI; Kashikar-Zuck, S. Pediatric Rheumatology Online Journal. 2019; 17.