Prasad Devarajan, MD
Title
Louise M. Williams Endowed Chair, Director of Nephrology and Hypertension
Appointment
Professor of Pediatrics and Developmental Biology
Email
prasad.devarajan@cchmc.org
Phone
513-636-4531
Fax
513-636-7407
Credentials
Premedical Studies: Bombay University, India, 1979
MD: Bombay University, India, 1985
Position History
1985-1986 Graduate Research, Dept of Physiology (Laboratory of Leon C. Moore, Ph.D.), SUNY Stony Brook, NY
1986-1989 Internship and Residency, Dept of Pediatrics, SUNY Stony Brook, NY
1989-1991 NIH Fellow, Pediatric Scientist Development Program, Hematology / Genetics, (Laboratory of Edward J. Benz, Jr., MD), Yale University School of Medicine, New Haven, Conn.
1991-1993 Postdoctoral Fellowship, Dept. of Pediatrics, Division of Nephrology, Yale University School of Medicine, New Haven, Conn.
1993-1995 Research Associate, Dept of Pathology and Cell Biology (Laboratory of Jon S. Morrow, MD, PhD), Yale University School of Medicine, New Haven, Conn.
1993-1994 Instructor, Dept of Pediatrics, Division of Nephrology, Yale University School of Medicine, New Haven, Conn.
1994-1998 Assistant Professor, Dept of Pediatrics, Division of Nephrology, Yale University School of Medicine, New Haven, Conn.
1998-1999 Assistant Professor & Director of Research, Dept of Pediatrics, Division of Nephrology, Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY
1999-2002 Associate Professor and Director of Research, Dept. of Pediatrics, Division of Nephrology, Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY
July 2002 Williams Professor of Pediatrics and Developmental Biology, Director of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio.
Awards and Honors
Best Doctors in America, 2008
Awarded "2005 Best Doctors"
1988-present Reviewer:
Lancet
Journal of Cell Biology,
Journal of Biological Chemistry,
Frontiers in Bioscience,
Quarterly Reviews in Biology,
American Journal of Physiology,
Journal of American Society of Nephrology,
Pediatric Nephrology,
Kidney International,
Laboratory Investigation,
Journal of Urology,
Journal of Hormone and Metabolic Research
1992-present Member, SPR, ASPN, ASN, NKF, AHA Council on Kidney in Cardiovascular Disease
1995-present Abstract reviewer, American Society of Nephrology
1999-present Abstract reviewer, Member of Awards Committee, Society for Pediatric Research
2000-present Council Member, Eastern Society for Pediatric Research
2000-present External Reviewer, NIH/NIDDK, Special Emphasis Review Panel
2001-present Ad Hoc Reviewer, NIH/NIDDK, Study Section
2002-present Member, American Society for Pediatric Nephrology Scientific Council
Research Grants and Contracts
NIH RO1 DK53289. Ankyrin: crucial linker in renal cell apoptotic cascades. April 2000 - March 2005. Principal Investigator.
NIH/NIDDK R01 DK0679749. Implications of the Ask1/JNK Pathway in ARF. 2005-2010. Principal Investigator.
NIH/NIDDK R21 DK070163. NGAL: A Novel Early Biomarker of Acute Renal Injury. 2005-2010. Principal Investigator.
NIH/NIDDK P50 DK52612. Mechanisms of Na, K-ATPase polarity in renal development. 2002-2007.
Cincinnati Children's Technology Validation Board Fund. A sensitive non-invastive method of detecting early sub-clinical renal injury. 2004-2005. Principal Investigator.
Cincinnati Children's Translational Research Initiative. A novel biomarker for early detection of renal injury. 2004-2006. Principal Investigator.
AHA Grant-in-Aid. A novel biomarker for early ischemic renal injury. 2004-2006. Principal Investigator.
Publications, Most Recent
Prasad Devarajan's publications as listed by PubMed
Del Rio M, Imam A, De Leon M, Gomez G, Mishra J, Ma Q, Parikh S, Devarajan P. The Death Domain of Ankyrin Interacts with Fas and Promotes Fas-mediated Apoptosis. J. Am. Soc. Nephrol. 15: 41-45, 2004.
Devarajan P. Has HGF Met Other Partners? Met-indenpendent epithelial morphogenesis induced by HGF. Am. J. Physiol. (Cell Physiol.), 286: C475-C477, 2004.
Braun MC, Kelly CN, Prada AE, Mishra J, Chand D, Devarajan P, Zahedi K. Human PRMT5 expression is enhanced during in vitro tubule forumation and after in vivo ischemic injury in renal epithelial cells. Am. J. Nephrol., 24: 250-257, 2004.
Mishra J, Mori K, Ma Q, Kelly C, Barasch J, Devarajan P. Neutrophil Gelatinase-Associated Lipocalin (NGAL): A novel urinary biomarker for cisplatin nephrotoxicity. Am. J. Nephrol. 24: 307-315, 2004.
Schwab K, Witte DP, Aronow BJ, Devarajan P, Potter SS, Patterson LT. Microarray analysis of Focal Segmental Glomerulosclerosis. Am. J. Nephrol. 24: 438-447, 2004.
Mishra J, Mori K, Ma Q, Kelly C, Yang J, Mitsnefes M, Barasch J, Devarajan P. Amelioration of ischemic acute renal injury by NGAL. J. Am. Soc. Nephrol. 15:3073-3082, 2004.
Devarajan P, Tarabishi R, Mishra J, Ma Q, Kourvetaris A, Vougiouka M, Boulikas T. Low renal toxicity of Lipoplatin compared to cisplatin in animals. Anticancer Res., 24:2193-2200, 2004.
Erkan E, Garcia C, Patterson LT, Mitsnefes MM, Mishra J, Kaskel F, Devarajan P. Induction of renal tubular cell apoptosis in FSGS: roles of proteinuria and Fas-dependent pathways. J. Am. Soc. Nephrol. 16: 398-407, 2005.
Dixon BP, Devarajan P, Mitsnefes MM. Neonatal renovascular hypertension due to prenatal traumatic retroperitoneal hematoma. Pediatr. Nephrol. 20: 670-672, 2005.
Mori K, Lee HT, Rapoport D, Drexler I, Foster K, Yang J, Schmidt-Ott, Chen X, Li JY, Weiss S, Mishra J, Cheema FH, Markowitz G, Suganami T, Sawai K, Mukoyama M, Kunis C, D'Agati V, Devarajan P, Barasch J. Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury. J. Clin. Invest. 115: 610-621, 2005.
Devarajan P. Cellular and molecular derangements in acute tubular necrosis. Curr. Opin. Pediatr. 17: 193-199, 2005.
Mishra J, Dent C, Tarabishi R, Mitsnefes MM, Ma Q, Kelly C, Ruff CM, Zahedi K, Shao M, Bean J, Mori K, Barasch J, Devarajan P. Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury following cardiac surgery. Lancet 365: 1231-1238, 2005.
Related Areas
This person works in these other areas at Cincinnati Children's Hospital Medical Center:
