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Alagille Syndrome

Alagille syndrome is a rare, inherited disorder in which bile flow from the liver is decreased and the there are fewer than normal bile ducts.

Alagille syndrome is a disorder that often affects the liver and other organs, including the heart, eyes, spine and kidneys.

Often, patients with Alagille syndrome have distinctive facial appearances. A small number of patients (about 15 percent) go on to develop severe liver disease and require liver transplantation.

This disorder is usually present at birth. Alagille syndrome is one of the most common inherited disorders that causes reduced bile flow within the liver. It occurs about once in every 100,000 births. 

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Causes of Alagille Syndrome

Signs and Symptoms of Alagille Syndrome

Diagnosis of Alagille Syndrome

Treatment for Alagille Syndrome

Long-Term Outlook

Last Updated: 10/2012