Health Topics

Hyper IgE Syndrome (Job’s Syndrome)

IgE, or immunoglobulin E, is an antibody that helps protect our body from certain infections. IgE is also made by the body and can cause allergic reactions. 

IgE can lead to allergic symptoms of:

    • Coughing, wheezing
    • Runny nose
    • Eye or throat irritation
    • Dry, red and itchy skin 

Job’s syndrome is a genetic alteration that can lead to a chronic skin rash (eczema) and chronic infections, especially in the skin and lung. 

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Signs and Symptoms of Hyper IgE Syndrome

Complications of Hyper IgE Syndrome

Treatment for Hyper IgE Syndrome


Last Updated: 07/2012