Services & Specialties
Immune Deficiencies and Dysregulation

Comprehensive Care for Children and Young Adults with Immune Deficiencies and Immune Dysregulation

Cincinnati Children’s Immune Deficiencies and Dysregulation Program provides care for all types of immune system disorders, including rare and complex conditions. We’re committed to helping you find answers and providing continuous, complete treatment from diagnosis to cure.

Our team features some of the country’s most experienced immunologists, including clinicians specializing in both immunology and stem cell transplantation. Working alongside a multidisciplinary team of specialists, we provide compassionate and coordinated care throughout your child’s treatment journey.

Why Choose Cincinnati Children’s

Immune deficiencies and dysregulation disorders often need complex treatment, and Cincinnati Children’s is one of only a few centers in the country with the resources to treat these conditions. Our skilled team combines expertise, collaborative care, and the latest tests and therapies to find the best solution for your child.

Personalized and Coordinated Care

We understand how overwhelming an immune deficiency diagnosis can be, which is why we make sure every family receives personal, one-on-one support. Our dedicated care managers will stay by your side from referral to treatment and beyond.

The care manager, an experienced immunology and transplantation nurse, will help schedule all appointments, treatments and follow-up care. The care manager will be your single point of contact throughout treatment, making sure you have a seamless experience. You will also receive a direct line for your care manager so that you can reach out with questions or concerns at any time.

Unique Testing Capabilities

Cincinnati Children’s is home to one of the country’s most advanced diagnostic immunology labs. With our unique technology and skilled research staff, we run tests not available at any other children’s hospital. These resources help us diagnose even the rarest immune conditions. Having an in-house immunology lab leads to faster test results, which means you can get answers quicker and your child can start treatment sooner.

National Recognition

Our program is part of the top-rated Cancer and Blood Diseases Institute. This program was ranked third among the nation’s pediatric cancer centers by U.S. News and World Report.

Immunologists with Transplantation Expertise

Our program features leading immunologists who specialize in all types of immune deficiencies. Many of our immunologists are also experienced transplantation doctors who specialize in blood and bone marrow transplants. This hybrid expertise allows us to provide continuous, complete treatment from diagnosis to cure.

Multi-Specialty Care

Immune deficiencies affect every child and young adult differently, which means your child may need treatment from a range of specialists. As part of Cincinnati Children’s, our program collaborates with world-class doctors from all areas of pediatric care. Specialists can include gastroenterologists, rheumatologists, pulmonologists and more. These specialists are all available under one roof. We can coordinate more convenient appointments that take less time out of your schedule.

A Focus on Research and Improving Outcomes

We’re dedicated to improving the lives of children and young adults with immune deficiencies through research and clinical trials. Our team includes doctors who are actively researching new treatments and tests while caring for children and young adults with immune deficiency disorders. This approach helps us quickly incorporate breakthrough therapies into our clinic.


#1 in the Nation

Our program is part of the Cincinnati Children’s Cancer and Blood Diseases Institute, which is ranked #1 in the nation for pediatric cancer care.

Learn More About Our Ranking

In the Best of Hands

When Hannah was diagnosed with hemophagocytic lymphohistiocytosis (HLH), her family came to Cincinnati Children’s for world-class care.
When Hannah was diagnosed with hemophagocytic lymphohistiocytosis (HLH), her family came to Cincinnati Children’s for world-class care. Read More