The Immune Deficiency and Dysregulation Program at Cincinnati Children’s conducts clinical and laboratory research for all types of immune system diseases. Many of our doctors are involved with research, which means we can access new and emerging therapies for our patients to improve outcomes. We also work closely with Cincinnati Children’s Cancer and Blood Diseases Institute researchers to bring breakthrough treatments into our clinics.

We offer all our patients the opportunity to participate in the Immunodeficiency Registry. As part of this registry, patients can donate blood and other biological samples for research into immune deficiency and dysregulation disorders. We also offer observational studies for patients with HLH, SCID, CGD and immune dysregulation disorders as part of the Primary Immune Deficiency Treatment Consortium. An observational study tracks a patient’s progress without offering a different treatment or therapy.

Our program is also currently studying new treatments for a range of immune system diseases. See our open clinical trials for HLH, XIAP deficiency, SCID, bone marrow transplant and others.