A photo of Evaline Alessandrini.

Evaline A. Alessandrini, MD, MSCE

  • Chief Operating Officer



I am a physician executive with over 20 years of dedication to clinical and operational activities with a relentless focus on the wellness of both patients and employees. I am driven by working with teams to design and implement healthcare transformation initiatives that lead to measurable improvements in safety, outcomes, experience and value.

I began my first faculty position in 1995 at the University of Pennsylvania and practiced clinically in pediatric emergency medicine at The Children's Hospital of Philadelphia. I was trained in health services research at Penn's Center for Clinical Epidemiology and Biostatistics, as well as the Leonard Davis Institute for Health Economics. I became the director of clinical transformation in CHOP's Institute to Transform and Advance Child Health. It was during this time in my career that I realized my passion was not in describing gaps in care, but in closing them. This led me to Cincinnati Children's in order to focus on "action-oriented" health services research and clinical operational improvements.

Between 2009 and 2017 at Cincinnati Children’s Hospital Medical Center, I served in clinical, research and training roles to drive Cincinnati Children's vision of being the leader in improving child health. I continued practicing pediatric emergency medicine in our Cincinnati Children's locations. As the assistant vice president for improvement integration within the James M. Anderson Center for Health Systems Excellence, I led clinical divisions in managing strategically aligned improvement portfolios focused on improving outcomes, experience and value of care. I also led a team that facilitated, aligned and transparently reported outcomes, and ratings and rankings, across the organization. In the research arena, I chaired the Place Outcomes Research Awards program that strategically allocated $1M annually to seed projects to improve care delivery and outcomes. I was also the director of the Quality Scholars Program in Health Care Transformation, training fellows and faculty to rigorously apply quality improvement methods to improve child health and healthcare. I also served as professor and associate chair of outcomes and process improvement in the Department of Pediatrics at the University of Cincinnati College of Medicine.

Prior to my role here at Cincinnati Children's, I served as executive vice president, chief medical officer and interim chief operating officer for the University of Cincinnati Health System, the only adult academic health system in our region.

Undergraduate Degree: Biology, Marquette University, Milwaukee, WI.

MD: Jefferson Medical College, Philadelphia.

Memberships: Phi Beta Kappa and Alpha Omega Alpha honor societies.

Pediatric Residency: Children’s National Medical Center, Washington, DC.

Chief Residency: Children’s National Medical Center, Washington, DC.

Fellowship: Pediatric Emergency Medicine, The Children's Hospital of Philadelphia.

Master's: Clinical Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine.

Award: NIH career development award (K-23) in pediatric health services research.

Research Areas

James M Anderson Center for Health Systems Excellence


Implementation of a Clinical Decision Support System for Children With Minor Blunt Head Trauma Who Are at Nonnegligible Risk for Traumatic Brain Injuries. Ballard, DW; Kuppermann, N; Vinson, DR; Tham, E; Hoffman, JM; Swietlik, M; Davies, SJ D; Alessandrini, EA; Tzimenatos, L; Bajaj, L; et al. Annals of Emergency Medicine. 2019; 73:440-451.

Defining Provider-Prioritized Domains of Quality in Pediatric Home-Based Hospice and Palliative Care: A Study of the Ohio Pediatric Palliative Care and End-of-Life Network. Thienprayoon, R; Alessandrini, E; Frimpong-Manso, M; Grossoehme, D. Journal of Palliative Medicine. 2018; 21:1414-1435.