Evaline (Evie) Alessandrini, MD, MSCE, is chief operating officer of Cincinnati Children’s, a nonprofit, comprehensive pediatric health system. As the leader in improving child health, Cincinnati Children's pushes the boundaries of what's possible in research, clinical care, education and innovation, so that every child can live their best possible life. The organization is consistently named one of the top pediatric hospitals in the nation in U.S. News & World Report’s Best Children’s Hospitals Honor Roll, and is the #3 recipient of pediatric research grants from the National Institutes of Health. Alessandrini previously served as executive vice president, chief medical officer and interim chief operations officer for UC Health, the University of Cincinnati’s affiliated healthcare system, between 2017 and 2021.
Alessandrini is a dynamic physician healthcare executive with 25 years of visionary leadership in top-ranked children’s healthcare systems and academic medicine. She has a proven track record of driving transformational change, advancing enterprise-wide innovation, and building high-performing, mission-driven teams that lead to measurable improvements in outcomes. Evie is an expert at shaping strategy, forging key partnerships, and navigating complex healthcare environments to elevate organizational performance and advance child health.
Alessandrini first joined Cincinnati Children’s in 2009. Between 2009 and 2017, she served in several administrative, research and training leadership roles. As the assistant vice president for improvement integration within the James M. Anderson Center for Health Systems Excellence, she led clinical divisions in managing strategically aligned improvement portfolios focused on improving outcomes, experience and value of care. Alessandrini was also director of the Cincinnati Children’s Place Outcomes Research Awards program and the Quality Scholars Program in Healthcare Transformation.
Prior to joining Cincinnati Children’s in 2009, Alessandrini served in a number of leadership roles at Children’s Hospital of Philadelphia (CHOP), including director of clinical transformation.
Alessandrini received a bachelor’s degree from Marquette University in Milwaukee and earned a medical degree from Jefferson Medical College in Philadelphia. She received a master’s degree in clinical epidemiology and biostatistics from the University of Pennsylvania. Alessandrini completed her residency and chief residency at Children’s National Medical Center in Washington, D.C., and a fellowship in pediatric emergency medicine at CHOP.
Alessandrini serves as chair of the executive committee of the board of the Regional Economic Development Initiative (REDI Cincinnati), a nonprofit focused on creating jobs and investment in the Cincinnati region. She also serves on the boards of the Greater Cincinnati chapter of the American Heart Association, the Cincinnati Museum Center, and the Ohio Children’s Hospital Association (OCHA). She is a member of the Cincinnati Regional Business Committee, and the Tocqueville Society of the United Way of Greater Cincinnati.
Implementation of a Clinical Decision Support System for Children With Minor Blunt Head Trauma Who Are at Nonnegligible Risk for Traumatic Brain Injuries. Annals of Emergency Medicine. 2019; 73(5):440-451.
Defining Provider-Prioritized Domains of Quality in Pediatric Home-Based Hospice and Palliative Care: A Study of the Ohio Pediatric Palliative Care and End-of-Life Network. Journal of Palliative Medicine. 2018; 21(10):1414-1435.
Systemwide Implementation of Patient-Reported Outcomes in Routine Clinical Care at a Children's Hospital. Joint Commission Journal on Quality and Patient Safety. 2018; 44(8):441-453.
The pediatric emergency department care experience: A quality measure. Patient Experience Journal. 2018; 5(2):32-53.
Applying the RE-AIM Framework for the Evaluation of a Clinical Decision Support Tool for Pediatric Head Trauma: A Mixed-Methods Study. Applied Clinical Informatics. 2018; 9(3):693-703.
The Pediatric Emergency Care Applied Research Network Registry: A Multicenter Electronic Health Record Registry of Pediatric Emergency Care. Applied Clinical Informatics. 2018; 9(2):366-376.
A Qualitative Analysis of Adolescent and Caregiver Acceptability of Universally Offered Gonorrhea and Chlamydia Screening in the Pediatric Emergency Department. Annals of Emergency Medicine. 2017; 70(6):787-796.e2.
Racial and Ethnic Differences in Antibiotic Use for Viral Illness in Emergency Departments. Pediatrics. 2017; 140(4).
Use of Traumatic Brain Injury Prediction Rules With Clinical Decision Support. Pediatrics. 2017; 139(4).
Risk Stratification to Decrease Unnecessary Diagnostic Imaging for Acute Appendicitis. Pediatrics. 2016; 138(3).