Benjamin Cocanougher, MD, PhD

Statistical signature of subtle behavioral changes in large-scale assays. Blanc, A; Laurent, F; Barbier-Chebbah, A; Van Assel, H; Cocanougher, BT; Jones, BM W; Hague, P; Zlatic, M; Chikhi, R; Vestergaard, CL; Jovanic, T; Masson, JB; Barré, C. PLoS Computational Biology. 2025; 21:e1012990.

Expanding therapeutic options for Pompe disease: a new small molecule inhibitor of glycogen synthase 1 (GYS1) shows preclinical promise in Pompe disease. Koch, RL; Cocanougher, BT; Lim, J; Raben, N; Kishnani, PS. Annals of translational medicine. 2024; 12:123.

Expanded phenotypic spectrum of neurodevelopmental and neurodegenerative disorder Bryant-Li-Bhoj syndrome with 38 additional individuals. Layo-Carris, DE; Lubin, EE; Sangree, AK; Clark, KJ; Durham, EL; Gonzalez, EM; Smith, S; Angireddy, R; Wang, XM; Weiss, E; Muss, C; Carere, DA; Bhoj, EJ K; Bryant, LM. European Journal of Human Genetics. 2024; 32:928-937.

The severity of MUSK pathogenic variants is predicted by the protein domain they disrupt. Cocanougher, BT; Liu, SW; Francescatto, L; Behura, A; Anneling, M; Jackson, DG; Deak, KL; Hornik, CD; ElMallah, MK; Pizoli, CE; Smith, EC; Tan, KG Q; McDonald, MT. Human Genetics and Genomics Advances. 2024; 5:100288.

LarvaTagger: manual and automatic tagging of Drosophila larval behaviour. Laurent, F; Blanc, A; May, L; Gándara, L; Cocanougher, BT; Jones, BM W; Hague, P; Barré, C; Vestergaard, CL; Crocker, J; Zlatic, M; Jovanic, T; Masson, JB. Bioinformatics. 2024; 40:btae441.

Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration. Khazaei, S; Chen, CC L; Andrade, AF; Kabir, N; Azarafshar, P; Morcos, SM; França, JA; Lopes, M; Lund, PJ; Danieau, G; Campos, EI; Kleinman, CL; Garzia, L; Jabado, N. Cell. 2023; 186:1162-1178.e20.

Single cell RNA-seq analysis reveals temporally-regulated and quiescence-regulated gene expression in Drosophila larval neuroblasts. Dillon, N; Cocanougher, B; Sood, C; Yuan, X; Kohn, AB; Moroz, LL; Siegrist, SE; Zlatic, M; Doe, CQ. Neural Development. 2022; 17:7.

A single-cell transcriptomic atlas of complete insect nervous systems across multiple life stages. Corrales, M; Cocanougher, BT; Kohn, AB; Wittenbach, JD; Long, XS; Lemire, A; Cardona, A; Singer, RH; Moroz, LL; Zlatic, M. Neural Development. 2022; 17:8.

Rapid Whole Genome Sequencing in Critically Ill Neonates Enables Precision Medicine Pipeline. Beaman, M; Fisher, K; McDonald, M; Tan, QK G; Jackson, D; Cocanougher, BT; Landstrom, AP; Hobbs, CA; Cotten, M; Cohen, JL. Journal of Personalized Medicine. 2022; 12:1924.

Circuits for integrating learned and innate valences in the insect brain. Eschbach, C; Fushiki, A; Winding, M; Afonso, B; Andrade, IV; Cocanougher, BT; Eichler, K; Gepner, R; Si, G; Valdes-Aleman, J; Samuel, AD; Truman, JW; Cardona, A; Zlatic, M. eLife. 2021; 10:e62567.