A photo of Cara Slagle.

Cara L. Slagle, MD


  • Attending Neonatologist, Division of Neonatology and Pulmonary Biology
  • Co-Director, Center for Acute Care Nephrology
  • Assistant Professor, UC Department of Pediatrics

About

Biography

Children are the future of our world, and helping neonates and their families through an incredibly challenging time is a privilege and honor. My clinical specialties include neonatology, neonatal acute kidney injury (AKI) and neonatal chronic kidney disease (CKD).

My research areas are focused on the kidneys. AKI is a common occurrence in the neonatal intensive care unit (NICU) secondary to the delicateness of underdeveloped kidneys in preterm infants, the use of medications and the environment required to mimic life outside the uterus to facilitate growth and treat preterm infants. Current research is demonstrating that AKI can have long-term effects and contribute to the development of CKD. Additionally, I am interested in neonatal dialysis and infant survival with fetal end-stage kidney disease.

During my residency, I developed a project to improve the diagnosis of AKI in the NICU and the reporting and referral when indicated to pediatric nephrology. I realized this was an important area that was understudied and underrecognized on a larger scale. Since that study, I joined the Neonatal Kidney Collaborative, which aims to improve the health of newborns with, or at risk for, kidney disease. Here at Cincinnati Children's, our research aims to reduce mortality and morbidity in neonates by improving detection, diagnosis and understanding of risk factors for AKI. In addition to AKI, I conduct research focusing on fetal end-stage kidney disease (ESKD) to improve survival and neonatal and childhood outcomes through an ongoing, multi-disciplinary collaborative quality approach. I am board certified in Pediatrics (2017) by the American Board of Pediatrics.

MD: University of Kentucky, Lexington, KY, 2013.

Residency: Medical University of South Carolina, Charleston, SC, 2016.

Chief Resident: Medical University of South Carolina, Charleston, SC, 2017.

Certification: Pediatrics, 2017.

Interests

Neonatal nephrology

Services and Specialties

Interests

AKI, ESRD and progression to CKD

Publications

Selected

Single-Center Experience on Growth in Infants Born With End-Stage Kidney Disease. Slagle, CL; Riddle, SL; McNelis, K; Claes, D. Journal of Renal Nutrition. 2023; 33:236-242.

Selected

Urine Biomarkers for the Assessment of Acute Kidney Injury in Neonates with Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia. Rumpel, J; Spray, BJ; Chock, VY; Kirkley, MJ; Slagle, CL; Frymoyer, A; Cho, SH; Gist, KM; Blaszak, R; Poindexter, B; Courtney, SE. The Journal of Pediatrics. 2022; 241:133-140.e3.

Selected

Association between Elevated Urine Neutrophil Gelatinase-Associated Lipocalin and Postoperative Acute Kidney Injury in Neonates. Slagle, CL; Goldstein, SL; Gavigan, HW; Rowe, JA; Krallman, KA; Kaplan, HC; Liu, C; Ehrlich, SR; Kotagal, M; Bondoc, AJ; Poindexter, BB. The Journal of Pediatrics. 2021; 238:193-201.e2.

Expanded discussion of kidney health monitoring for critically ill term and late preterm infants after acute kidney injury: a report from the Neonatal Kidney Health Consensus Workshop. Vuong, KT; Liberio, BM; Schwartz, SR; Menon, S; Mohamed, TH; Soranno, DE; Johnson, KS; Jetton, JG; Merrill, KA; Hanna, M; Beck, T; Ambalavanan, N; Gorga, SM; Harer, MW. Pediatric Nephrology. 2025; 40:2993-3004.

Hyperglycemia and kidney outcomes in critically ill children and young adults on continuous kidney replacement therapy. Goswami, S; Gist, KM; Bjornstad, P; Ciccia, E; Deep, A; Gelbart, B; Menon, S; Marinari, E; Ollberding, NJ; Qutob, D; Alobaidi, R; Alhamoud, I; Arikan, AA; Ahern, E. Pediatric Nephrology. 2025; 40:2957-2966.

Renal Physiology: From Fetus to Newborn and Beyond. Holland, B; Slagle, CL; Starr, MC. Advances in Pediatrics. 2025; 72:143-156.

Thrombocytopenia in Children and Young Adults Undergoing Continuous Renal Replacement Therapy: A WE-ROCK Study. Basalely, A; Gist, KM; Stanski, NL; Fuhrman, DY; Seo, JD; Ollberding, NJ; Strong, A; Damian, M; Morgan, C; Reynaud, S; Brown, CL; Burrell, A; Dash, A; Ehrlich, JL. Blood Purification. 2025; 54:322-333.

Urinary Neutrophil Gelatinase-Associated Lipocalin Values in Preterm Neonates: A Systematic Review and Meta-analysis. Mohamed, T; Alexander, R; Davidson, B; Klamer, B; Gehred, A; Starr, MC; Slagle, C; Krawczeski, C; Harer, MW. American Journal of Perinatology: neonatal and maternal-fetal medicine. 2025; 42:683-688.

Framework for Kidney Health Follow-Up Among Neonates With Critical Cardiac Disease: A Report From the Neonatal Kidney Health Consensus Workshop. Gorga, SM; Beck, T; Chaudhry, P; Defreitas, MJ; Fuhrman, DY; Joseph, C; Krawczeski, CD; Kwiatkowski, DM; Starr, MC; Harer, MW; Charlton, JR; Askenazi, DJ; Selewski, DT; Gist, KM. Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease. 2025; 14:e040630.

Approaches to neonatal acute kidney injury consultation and follow-up: results of a provider survey. Feeney, A; Slagle, CL; Harer, MW; Charlton, JR; Mohamed, T; Askenazi, DJ; Menon, S; Selewski, DT; Starr, MC. Journal of Perinatology. 2025; 45:397-398.

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