A photo of Cara Slagle.

Cara L. Slagle, MD


  • Attending Neonatologist, Division of Neonatology and Pulmonary Biology
  • Co-Director, Center for Acute Care Nephrology
  • Assistant Professor, UC Department of Pediatrics

About

Biography

Children are the future of our world, and helping neonates and their families through an incredibly challenging time is a privilege and honor. My clinical specialties include neonatology, neonatal acute kidney injury (AKI) and neonatal chronic kidney disease (CKD).

My research areas are focused on the kidneys. AKI is a common occurrence in the neonatal intensive care unit (NICU) secondary to the delicateness of underdeveloped kidneys in preterm infants, the use of medications and the environment required to mimic life outside the uterus to facilitate growth and treat preterm infants. Current research is demonstrating that AKI can have long-term effects and contribute to the development of CKD. Additionally, I am interested in neonatal dialysis and infant survival with fetal end-stage kidney disease.

During my residency, I developed a project to improve the diagnosis of AKI in the NICU and the reporting and referral when indicated to pediatric nephrology. I realized this was an important area that was understudied and underrecognized on a larger scale. Since that study, I joined the Neonatal Kidney Collaborative, which aims to improve the health of newborns with, or at risk for, kidney disease. Here at Cincinnati Children's, our research aims to reduce mortality and morbidity in neonates by improving detection, diagnosis and understanding of risk factors for AKI. In addition to AKI, I conduct research focusing on fetal end-stage kidney disease (ESKD) to improve survival and neonatal and childhood outcomes through an ongoing, multi-disciplinary collaborative quality approach. I am board certified in Pediatrics (2017) by the American Board of Pediatrics.

MD: University of Kentucky, Lexington, KY, 2013.

Residency: Medical University of South Carolina, Charleston, SC, 2016.

Chief Resident: Medical University of South Carolina, Charleston, SC, 2017.

Certification: Pediatrics, 2017.

Interests

Neonatal nephrology

Services and Specialties

Neonatology, Center for Acute Care Nephrology CACN

Interests

AKI, ESRD and progression to CKD

Research Areas

Neonatology

Insurance Information

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Publications

Selected

Single-Center Experience on Growth in Infants Born With End-Stage Kidney Disease. Slagle, CL; Riddle, SL; McNelis, K; Claes, D. Journal of Renal Nutrition. 2023; 33:236-242.

Selected

Urine Biomarkers for the Assessment of Acute Kidney Injury in Neonates with Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia. Rumpel, J; Spray, BJ; Chock, VY; Kirkley, MJ; Slagle, CL; Frymoyer, A; Cho, SH; Gist, KM; Blaszak, R; Poindexter, B; Courtney, SE. The Journal of Pediatrics. 2022; 241:133-140.e3.

Selected

Association between Elevated Urine Neutrophil Gelatinase-Associated Lipocalin and Postoperative Acute Kidney Injury in Neonates. Slagle, CL; Goldstein, SL; Gavigan, HW; Rowe, JA; Krallman, KA; Kaplan, HC; Liu, C; Ehrlich, SR; Kotagal, M; Bondoc, AJ; Poindexter, BB. The Journal of Pediatrics. 2021; 238:193-201.e2.

Caffeine and kidney function at two years in former extremely low gestational age neonates. Harer, MW; Griffin, R; Askenazi, DJ; Fuloria, M; Guillet, R; Hanna, M; Schuh, MP; Slagle, C; Woroniecki, R; DeFreitas, M; Starr, MC; Swanson, JR; Zappitelli, M; Charlton, JR. Pediatric Research. 2024; 95:257-266.

Current state of renal NIRS monitoring in the NICU: results from a CHNC Survey. Harer, MW; Rumpel, JA; Stoops, C; Slagle, CL; Liberio, B; Daniel, J; Hoffman, SB; Agarwal, N; Khattab, MG; Rais-Bahrami, K; Perazzo, S. Journal of Perinatology. 2023; 43:1047-1049.

Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease (WE-ROCK). Menon, S; Krallman, KA; Arikan, AA; Fuhrman, DY; Gorga, SM; Mottes, T; Ollberding, N; Ricci, Z; Stanski, NL; Selewski, DT; Uber, AM; Van Wyk, B; Webb, TN; Zangla, EE. Kidney International Reports. 2023; 8:1542-1552.

Acute kidney injury and early fluid load in a retrospective cohort of neonatal sepsis. Al Gharaibeh, FN; Mohan, S; Santoro, MA; Slagle, CL; Goldstein, SL. Pediatric Nephrology. 2023; 38:1971-1977.

Relationship between piperacillin concentrations, clinical factors and piperacillin/tazobactam-associated acute kidney injury. Girdwood, ST; Hasson, D; Caldwell, JT; Slagle, C; Dong, S; Fei, L; Tang, P; Vinks, AA; Kaplan, J; Goldstein, SL. Journal of Antimicrobial Chemotherapy. 2023; 78:478-487.

Association of Fluid Balance With Short- and Long-term Respiratory Outcomes in Extremely Premature Neonates: A Secondary Analysis of a Randomized Clinical Trial. Starr, MC; Griffin, R; Gist, KM; Segar, JL; Raina, R; Guillet, R; Nesargi, S; Menon, S; Anderson, N; Askenazi, DJ; Selewski, DT. JAMA network open. 2022; 5:e2248826.

Connecting Brain and Kidney: The Systemic Effects of Acute Kidney Injury After Cardiac Surgery. Stanski, NL; Slagle, CL; Gist, KM. The Annals of Thoracic Surgery. 2022; 114:2354-2355.

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4.6
Overall Patient Rating