Michael Seifert, MD, MSCI, FAST
- Division Director, Division of Nephrology and Hypertension
- Professor, UC Department of Pediatrics
About
Biography
I specialize in pediatric kidney transplantation, and I’m passionate about helping children and families navigate complex medical challenges. I take pride in spending time with my patients and their families, getting to know them beyond the clinic and understanding what matters most in their lives. My goal is to be a good educator about your child’s illness and our plan of care, always welcoming your input and making decisions together whenever possible.
My journey to medicine was inspired by incredible teachers and clinicians in pediatric nephrology who made even the most complicated topics approachable and engaging. I find it deeply rewarding to care for kidney transplant patients, as restoring kidney function can have an immediate and profound impact on a child’s health and quality of life.
In addition to my clinical work, I lead a translational research laboratory focused on understanding acute and chronic kidney transplant injury in children. We’re working to develop better non-invasive biomarkers for transplant rejection and studying outcomes in young adults who received transplants as children. Using advanced spatial biology techniques, our ultimate goal is to improve diagnostics and therapies for pediatric kidney transplant recipients.
Outside of work, I enjoy working and being outdoors, as well as pursuing my woodworking hobby at home when time allows.
MD: University of Connecticut
Residency: Pediatrics, University of Connecticut
Fellowship: Pediatric Nephrology, Boston Children's Hospital
Interests
Pediatric kidney transplantation
Services and Specialties
Interests
Pediatric kidney transplantation; kidney transplant spatial biology and transcriptomics; early life stress-induced cardiovascular and kidney disease
Research Areas
- Nephrology and Hypertension
- transplant-immunology
Publications
Under-enrollment in rare kidney disease trials: lessons learned from the PRIVENT recurrent FSGS. Nephrology Dialysis Transplantation. 2026; 41(9):1755-1758.
Alemtuzumab Induction via Intravenous vs. Subcutaneous Administration in Pediatric Kidney Transplantation. Pediatric Transplantation. 2026; 30(8):e70424.
Polygenic risk scores and HLA class II variants are biomarkers of corticosteroid response in childhood nephrotic syndrome. Kidney International. 2026; 109(6):1256-1268.
Combination Automated Microfluidics Measurement of Urine C-C Motif Ligand 2, CXC-Motif Chemokine 9, CXC-Motif Chemokine 10, and Vascular Endothelial Growth Factor A for Monitoring Patients with a Kidney Transplant. American Society of Nephrology. Clinical Journal. 2025; 20(5):719-732.
Detection of Subclinical Rejection in Pediatric Kidney Transplantation: Current and Future Practices. Pediatric Transplantation. 2024; 28(6):e14836.
T-bet + B Cells in Humans: Protective and Pathologic Functions. Transplantation. 2024; 108(8):1709-1714.
A multicenter prospective study to define the natural history of BK viral infections in kidney transplantation. Transplant Infectious Disease. 2024; 26(2):e14237.
Prevalence of mycophenolate mofetil discontinuation and subsequent outcomes in pediatric kidney transplant recipients: A PNRC study. Pediatric Transplantation. 2024; 28(1):e14628.
Follow-up biopsies identify high rates of persistent rejection in pediatric kidney transplant recipients after treatment of T cell-mediated rejection. Pediatric Transplantation. 2024; 28(1):e14617.
Validation of a prediction system for risk of kidney allograft failure in pediatric kidney transplant recipients: An international observational study. American Journal of Transplantation. 2023; 23(10):1561-1569.
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