Sam Vaughn, MD, PhD

Distribution of the J1 haplotype variant rs2267439 across CYP2D6 diplotypes and its impact on risperidone metabolism. Asensi Canto, A; Wang, WY; Boone, EC; Retke, B; Toren, P; Yoo, B; Kehinde, O; Vaughn, SE; Amaeze, O; Oni-Orisan, A; Gaedigk, A; Ramsey, LB. Pharmacogenetics and Genomics. 2026.

104.4 Integrating Psychiatric Care Into the Pediatric Emergency Department: Implementation and Early Outcomes. Vaughn, SE. Journal of the American Academy of Child and Adolescent Psychiatry. 2026; 65(10):s154-s155.

Impact of CYP2D6 Genotype and Inhibitor Use on Risperidone Metabolism in Children: Functional Insights Into the *17 and *29 Alleles. Bennett, MH; Poweleit, EA; Vaughn, SE; Retke, B; Toren, P; Strawn, JR; Ramsey, LB. Clinical and Translational Science. 2026; 19(3):e70525.

Leveraging Primary Care Resources Through Quality Improvement to Increase Follow-up After Mental Health Emergency Department Visits. Krantz, LB; Vaughn, SE; Mcclure, JM; Walters, J; Gehring, E; Mahan, A; Spitznagel, J; Reisman, T; Brinkman, WB. Pediatric Quality & Safety. 2026; 11(6):e944.

Cytochrome P450 2D6 *17 and *29 Allele Activity for Risperidone Metabolism: Advancing Precision Medicine Health Equity. Kehinde, O; Vaughn, SE; Amaeze, O; Toren, P; Retke, B; Oni-Orisan, A; Ramsey, LB. Clinical Pharmacology and Therapeutics. 2025; 118(5):1152-1160.

Catatonia responsive to corticosteroids in a patient with an SCN2A variant. Senko, K; Saddoris, KL; Baus, E; Soe, K; Vaughn, SE. American Journal of Medical Genetics, Part C: Seminars in Medical Genetics. 2024; 196(4):e32101.

2.34 Variability in Sertraline Pharmacokinetics Explained By CYP2C19 and CYP2B6. Ramsey, LB; Poweleit, EA; Vaughn, S; Momper, J; Desta, Z; Strawn, JR. Journal of the American Academy of Child and Adolescent Psychiatry. 2024; 63(10):s194.

Machine Learning-Based Prediction of Escitalopram and Sertraline Side Effects With Pharmacokinetic Data in Children and Adolescents. Poweleit, EA; Vaughn, SE; Desta, Z; Dexheimer, JW; Strawn, JR; Ramsey, LB. Clinical Pharmacology and Therapeutics. 2024; 115(4):860-870.

84 Using Opportunistic Sampling and Remnant Blood Samples to Develop Pediatric Pharmacokinetic Models to Inform Antidepressant Dosing. Strawn, JR; Poweleit, EA; Taylor, ZL; Mizuno, T; Vaughn, S; Desta, Z; Stancil, S; Ramsey, LB. Journal of Clinical and Translational Science. 2024; 8(s1):22-23.

Influence of CYP2D6 Metabolizer Status on Risperidone and Paliperidone Tolerability in Children and Adolescents. Kanu, AA; Johnston, MM; Poweleit, EA; Vaughn, SE; Strawn, JR; Ramsey, LB. Journal of Child and Adolescent Psychopharmacology. 2024; 34(1):34-41.