Study Demonstrates Successful Implementation of ERAS
Andrew Strine, MD, assistant professor and co-director of the Comprehensive Fertility Care and Preservation Program at Cincinnati Children's, was one of the leads in a landmark eight-center study that demonstrated the successful implementation of an ERAS protocol for major bladder reconstructive surgery. These surgeries involved procedures such as bladder augmentation and catheterizable channel creation. The ERAS approach is different from traditional methods. Rather than requiring patients to fast, ERAS protocols call for maintaining perioperative nutrition.
Clear liquids are allowed until two hours before surgery, and solids until eight hours before, to keep the gut fed. A preoperative carbohydrate drink is provided, which helps nourish the gut lining and prevent bacterial translocation that can occur with prolonged starvation periods.
The study included 40 patients across eight major children's hospitals. The researchers proved successful implementation of 16–20 of the defined 20 ERAS elements at each site was possible. This was achieved by following a well-organized plan involving different specialists working together, checking progress regularly and adjusting as needed.
The benefits have been striking even in this initial cohort. Patients on the ERAS pathway had a median hospital stay of just six days, compared to 11 days for similar cases managed traditionally. Importantly, this shorter hospitalization did not increase readmission rates.
Key Features of ERAS Protocols
After surgery, ERAS focuses on strategies such as:
- Early initiation of liquids and solids once tolerated, often the day of or day after surgery
- Careful management of IV fluids to avoid fluid overload
- Multimodal pain control using regional anesthetics and minimizing systemic narcotics
- Getting patients ambulatory as soon as possible
The ERAS protocol helps patients recover faster and get discharged sooner than the traditional pathway. In the past, patients would wait longer to eat or ambulate, and they would be given narcotics that can slow recovery.
Challenges and Future Directions
Wider implementation across smaller centers with limited resources remains a challenge. Strine emphasizes the importance of engaging local champions to drive the adoption of standardized ERAS protocols tailored to each institution.
"You need an engaged champion from each key area—surgery, anesthesia, nursing and hospital leadership," Strine says. Driving this kind of practice change requires reinforcement, monitoring compliance and adjusting the protocol as needed. However, the goal is to decrease variability in perioperative care.
Ongoing Research and Impacts on Patient Outcomes
As the study continues, the team will analyze impacts on key metrics like complication rates, pain scores, emergency room visits, reoperations and patient-reported quality of life measures. The early results demonstrating feasibility and a reduction in length of stay are highly encouraging.
"These patients clearly have a better hospital experience and higher quality of life at home with ERAS compared to traditional pathways," Strine explains.
As more data accumulates to validate improved outcomes, the belief is that these protocols will be broadly adopted to enhance recovery for other surgeries as well.
The Evolving Future of Pediatric Urological Surgery
This pivotal multi-center work proves that evidence-based ERAS protocols can be successfully implemented even for complex pediatric urological procedures. Pediatric urologists have a unique opportunity to optimize surgical recovery with these protocols. Following pioneering centers like Cincinnati Children's, the future of pediatric perioperative care is evolving toward a multidisciplinary, patient-centered model, driving best practices and achieving superior outcomes.
(Published December 2025)
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