Cincinnati Children’s Hospital Medical Center, which includes the Cincinnati Children’s Research Foundation (CCRF), is a nonprofit hospital and research center pioneering breakthrough treatments, providing outstanding family-centered patient care and training healthcare professionals for the future. Cincinnati Children’s is accredited to conduct clinical research by The Association for the Accreditation of Human Research Protection Programs (AAHRPP) and is the third highest recipient of NIH research grant funding among comprehensive pediatric centers. Annually, it has more than 2,500 investigator-initiated, industry- and federally-sponsored IRB active protocols including pediatric Phase I-IV, and select adult Phase I-IV clinical studies.
Cincinnati Children’s has been conducting pediatric research since 1931. Achievements by our researchers include such breakthrough discoveries as the Sabin oral vaccine, the first practical heart-lung machine that made open-heart surgery possible and the discovery of the key ingredients of the surfactant preparation used throughout the world to save the lives of thousands of premature infants each year. More recently, Cincinnati Children’s researchers were responsible for the discovery and testing of a vaccine (Rotarix) that prevents rotavirus infection, which kills half a million children throughout the world each year.
About the Office for Clinical and Translational Research − Meeting Your Clinical Trial Needs
The Office for Clinical and Translational Research (OCTR) functions as a “one-stop” clinical research support center – from concept development to publication. Our mission is to provide clinical investigators and sponsors with comprehensive support services, research tools, experienced research personnel, and facilities to conduct or facilitate pediatric and adult clinical research – from identification and development of research opportunities to phase I through phase IV clinical research trials.
Members of our OCTR team act as research liaisons among our sponsors, contract research organizations (CROs), investigators, laboratories, research pharmacy and necessary departments. Support services provided by the OCTR include: identification and development of research opportunities (protocol development), contracts and budgets (for all funding sources), regulatory affairs, project management (single- and multi-center studies), data management, research study management, participant recruitment and retention, integration with institutional research partners and publication support.
For sponsors and CROs, the OCTR assists to place, coordinate and/or facilitate select pediatric or adult clinical studies conducted at inpatient and outpatient Cincinnati Children’s facilities. The OCTR understands sponsors’ needs and is committed to conducting clinical studies with heightened attention to time constraints and budgets. The OCTR has access to all of Cincinnati Children’s therapeutic divisions as well as collaborating with other Cincinnati Children’s research centers of expertise to meet your study needs.