Clinical Trials / Research Studies
Study for Children and Teens With Down Syndrome
Why are we doing this research?
Cincinnati Children's is conducting a research study to evaluate the use of a medication, methylphenidate (QuillivantXR), with children and teens with Down syndrome and ADHD.
Who can participate?
Children and teens 6 to 17 years old with Down syndrome and diagnosed or suspected ADHD may be eligible to participate.
Conditions
- Down Syndrome
- ADD / ADHD
What will happen in the study?
This study includes 13 study visits (5 of the 13 are telehealth). 2 of these visits are screening visits. The visits include some or all of these components:
- Participant cognitive and behavioral assessments
- Parent/caregiver forms and one parent interview
- Teacher report forms
- Interview with a study clinician
- EKG, weight, and blood pressure
You will be given a consent form that thoroughly explains all the details of the study. A member of the study staff will review the consent form with you and will be sure that all your questions are answered.
What are the good things that can happen from this research?
Families will receive a comprehensive assessment, including intelligence, behavioral and cognitive assessments at no charge. Families will also receive 4 months of a therapeutic dose of methylphenidate (QuillivantXR) at no charge. The participant will receive cardiac and medical oversight for the duration of the study. Overall, the information learned from this study may help children with Down syndrome and ADHD and it may also help doctors with their diagnostic and treatment efforts in the future.
What are the bad things that can happen from this research?
Possible risks and discomforts will be discussed with parents or guardians interested in learning more about the study.
Will you/your child be paid to be in this research study?
Families will receive up to $225.
Contact
Emily Hoffman
513-803-3641
emily.hoffman1@cchmc.org
Cincinnati Children’s Hospital Medical Center
3333 Burnet Ave.
Cincinnati, OH 45229-3039
Study Doctor
Anna Esbensen, PhD
Developmental and Behavioral Pediatrics - Psychology
Cincinnati Children’s Hospital Medical Center
Tanya Froehlich, MD
Developmental & Behavioral Pediatrics
Cincinnati Children’s Hospital Medical Center
3333 Burnet Avenue, Cincinnati, Ohio 45229-3026
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