Clinical Trials / Research Studies
Clinical Trials / Research Studies

A Study to Understand the Impact of Youth Onset Obesity and Type 2 Diabetes on the Neurovascular Unit

Why are we doing this research?

Cincinnati Children's is conducting a research study, sometimes known as a clinical study, to understand the effects of diabetes on the brain. We will also be looking at blood vessels in the body and how they relate to blood vessels in the brain.

Who can participate?

Teens and young adults 13 to 19 years old with and without type 2 diabetes may be eligible to participate.


  • Diabetes

What will happen in the study?

This study consists of a single visit lasting 6 hours. There is an option to return for a study visit 3 years later.

Participants will:

  • Have height, weight and blood pressure measurements taken
  • Answer questions about your health and healthcare
  • Have a fasting blood draw and possibly an IV placed
  • Have an MRI for about one hour (no IV, no radiation)
  • Participate in puzzles and questions
  • Have the option of an ultrasound study of blood vessels
  • Have the option of bone scans

Young adults or parents interested in having their teen participate will be given a consent form that thoroughly explains all of the details of the study. A member of the study staff will review the consent form with you and will be sure that all of your questions are answered.

What are the good things that can happen from this research?

You or your teen may not have a direct medical benefit. However, the information we obtain from this study may help us to learn if type 2 diabetes affects the brain.

What are the bad things that can happen from this research?

There is very little risk to participants in this research study. We will discuss possible risks and discomforts with parents or guardians interested in learning more about the study.

Will you/your child be paid to be in this research study?

Participants will receive up to $200 for time and effort throughout the course of the study.


Contact Us.
Study Team

Study Doctor

Contact Us.Amy Sanghavi Shah, MD, MS
Pediatric Endocrinology
Director, Adolescent Type 2 Diabetes Program
Cincinnati Children’s Hospital Medical Center