A photo of Mekibib Altaye.

Mekibib Altaye, PhD


  • Director, Data Management and Analysis Center
  • Professor, UC Department of Pediatrics

About

Biography

Many well-thought-out research studies fail to answer the questions they pose because of a lack of planning for appropriate study design and subsequent analysis.

I’m passionate about providing optimal design and analysis plans for such projects, so that the results of the study clearly answer the questions posed. My research focuses on the design and analysis of correlated data, particularly high-dimensional data obtained from neuroimaging studies such as MRI, functional MRI (fMRI), diffusion tensor imaging (DTI) and magnetic resonance spectroscopy (MRS).

I have been a researcher for more than 22 years and began my work at Cincinnati Children’s in 2001. My research is funded by the National Institutes of Health (NIH), the Centers for Disease Control and Prevention (CDC) and the Department of Defense (DoD).

One of my significant research contributions was the development of the first infant brain template used to make inferences about neuroimaging research (2008). Since then, many researchers have downloaded this template for use in their studies.

In addition to authoring and co-authoring more than 150 peer-reviewed publications and a book chapter, I have presented my work at national meetings.

I’m currently the director of the Data Management and Analysis Center within the Division of Biostatistics and Epidemiology at Cincinnati Children’s. In this role, — where I often work with other biostatisticians, epidemiologists and informaticists — I enjoy helping others, solving problems and making sense of data. My work takes place in a highly collaborative environment; I partner with teams of basic and clinical scientists representing a variety of disciplines that leverage neuroimaging as part of their studies.

Publications

Association between brain structural network efficiency at term-equivalent age and early development of cerebral palsy in very preterm infants. Kline, JE; Yuan, W; Harpster, K; Altaye, M; Parikh, NA. NeuroImage. 2021; 245.

Trends in Number of Women Speakers at the American Head and Neck Society Meetings, 2007-2019. Hernandez Brandi, M; Howell, R; Power, A; Tabangin, M; Altaye, M; Zender, CA; Takiar, V; Tang, AL. JAMA Otolaryngology - Head and Neck Surgery. 2021; 147:1053-1058.

S100 Proteins, Cytokines, and Chemokines as Tear Biomarkers in Children with Juvenile Idiopathic Arthritis-associated Uveitis. Angeles-Han, ST; Miraldi Utz, V; Thornton, S; Schulert, G; Rodriguez-Smith, J; Kauffman, A; Sproles, A; Mwase, N; Hennard, T; Grom, A; et al. Ocular Immunology and Inflammation. 2021; 1-5.

White Matter Alteration Following SWAT Explosive Breaching Training and the Moderating Effect of a Neck Collar Device: A DTI and NODDI Study. Yuan, W; Dudley, J; Slutsky-Ganesh, AB; Leach, J; Scheifele, P; Altaye, M; Barber Foss, KD; Diekfuss, JD; Rhea, CK; Myer, GD. Military Medicine. 2021; 186:1183-1190.

Modified Head and Neck Swallow Scale: Using EORTC-QLQ-H&N35 to Predict Overall Survival. von Allmen, D; Tang, A; Takiar, V; Zender, C; Romeo, S; Masch, J; Casper, K; Patil, Y; Wilson, K; Khosla, S; et al. Laryngoscope. 2021; 131:2478-2482.

Elevated Anthropometric and Metabolic Indicators among Young Adult Offspring of Mothers with Pregestational Diabetes: Early Results from the Transgenerational Effect on Adult Morbidity Study (the TEAM Study). Bowers, K; Ehrlich, S; Dolan, LM; Gupta, R; Altaye, M; Ollberding, NJ; Szczesniak, R; Catalano, P; Smith, E; Khoury, JC. Journal of Diabetes Research. 2021; 2021.

High School Sports-Related Concussion and the Effect of a Jugular Vein Compression Collar: A Prospective Longitudinal Investigation of Neuroimaging and Neurofunctional Outcomes. Yuan, W; Diekfuss, JA; Barber Foss, KD; Dudley, JA; Leach, JL; Narad, ME; Dicesare, CA; Bonnette, S; Epstein, JN; Logan, K; et al. Journal of Neurotrauma. 2021; 38:2811-2821.

A Roadmap for Building Data Science Capacity for Health Discovery and Innovation in Africa. Beyene, J; Harrar, SW; Altaye, M; Astatkie, T; Awoke, T; Shkedy, Z; Mersha, TB. Frontiers in Public Health. 2021; 9.

Deep Multimodal Learning From MRI and Clinical Data for Early Prediction of Neurodevelopmental Deficits in Very Preterm Infants. He, L; Li, H; Chen, M; Wang, J; Altaye, M; Dillman, JR; Parikh, NA. Frontiers in Neuroscience. 2021; 15.

Altered functional network connectivity and working memory dysfunction in adolescents with epilepsy. Vannest, J; Radhakrishnan, R; Gutierrez-Colina, AM; Wade, SL; Maloney, T; Combs, A; Turnier, L; Merder, S; Altaye, M; Tzipi-Horowitz-Kraus, ; et al. Brain Imaging and Behavior. 2021; 15:2513-2523.