A photo of Mekibib Altaye.

Mekibib Altaye, PhD


  • Director, Data Management and Analysis Center
  • Professor, UC Department of Pediatrics

About

Biography

Many well-thought-out research studies fail to answer the questions they pose because of a lack of planning for appropriate study design and subsequent analysis.

I’m passionate about providing optimal design and analysis plans for such projects, so that the results of the study clearly answer the questions posed. My research focuses on the design and analysis of correlated data, particularly high-dimensional data obtained from neuroimaging studies such as MRI, functional MRI (fMRI), diffusion tensor imaging (DTI) and magnetic resonance spectroscopy (MRS).

I have been a researcher for more than 22 years and began my work at Cincinnati Children’s in 2001. My research is funded by the National Institutes of Health (NIH), the Centers for Disease Control and Prevention (CDC) and the Department of Defense (DoD).

One of my significant research contributions was the development of the first infant brain template used to make inferences about neuroimaging research (2008). Since then, many researchers have downloaded this template for use in their studies.

In addition to authoring and co-authoring more than 150 peer-reviewed publications and a book chapter, I have presented my work at national meetings.

I’m currently the director of the Data Management and Analysis Center within the Division of Biostatistics and Epidemiology at Cincinnati Children’s. In this role, — where I often work with other biostatisticians, epidemiologists and informaticists — I enjoy helping others, solving problems and making sense of data. My work takes place in a highly collaborative environment; I partner with teams of basic and clinical scientists representing a variety of disciplines that leverage neuroimaging as part of their studies.

Publications

Understanding racial disparities in childhood asthma using individual- and neighborhood-level risk factors. Correa, E; Ding, L; Beck, AF; Brokamp, C; Altaye, M; Kahn, RS; Mersha, TB. Journal of Allergy and Clinical Immunology. 2022.

Predictors of Stimulant Medication Continuity in Children with Attention-Deficit/Hyperactivity Disorder. Kamimura-Nishimura, K; Brinkman, W; Epstein, J; Zhang, Y; Altaye, M; Froehlich, T. Journal of Developmental and Behavioral Pediatrics. 2022; 43:311-319.

Comprehensive Assessment of Quality of Life, Functioning, and Mental Health in Children With Juvenile Idiopathic Arthritis and Noninfectious Uveitis. McDonald, J; Cassedy, A; Altaye, M; Andringa, J; Cooper, AM; Drews-Botsch, C; Engelhard, G; Hennard, T; Holland, GN; Jenkins, K; et al. Arthritis Care and Research. 2022; 74:1311-1320.

The Construction of a Predictive Composite Index for Decision-Making of CSF Diversion Surgery in Pediatric Patients following Prenatal Myelomeningocele Repair. Mangano, FT; Altaye, M; Stevenson, CB; Yuan, W. American Journal of Neuroradiology. 2022.

Changes in Bone Marrow Adipose Tissue in Transgender and Gender Non-Conforming Youth Undergoing Pubertal Suppression: A Pilot Study. Nasomyont, N; Meisman, AR; Ecklund, K; Vajapeyam, S; Cecil, KM; Tkach, JA; Altaye, M; Corathers, SD; Conard, LA; Kalkwarf, HJ; et al. Journal of Clinical Densitometry. 2022.

Relationship Between Hypovitaminosis D and Fractures Among Adolescents With Overweight or Obesity. Segal, D; Ziv, A; Meisman, A; Fry, J; Altaye, M; Gordon, CM. Clinical Pediatrics. 2022.

Early-Stage Glottic Carcinoma in the United States: Demographics and Treatment Choice. Friedman, AD; Gengler, I; Altaye, M; Tabangin, ME. Laryngoscope. 2022.

Magnetic resonance spectroscopy brain metabolites at term and 3-year neurodevelopmental outcomes in very preterm infants. Illapani, VS P; Edmondson, DA; Cecil, KM; Altaye, M; Kumar, M; Harpster, K; Parikh, NA. Pediatric Research. 2022; 92:299-306.

Descriptors in Letters of Recommendation for Otolaryngology Residency Across Gender, Race, and Time. Aunins, B; Badhey, A; Conroy, Z; Howard, JJ M; Myer, C; Altaye, M; Tang, AL. Journal of Surgical Education. 2022; 79:935-942.

Acute histologic chorioamnionitis independently and directly increases the risk for brain abnormalities seen on magnetic resonance imaging in very preterm infants. Jain, VG; Kline, JE; He, L; Kline-Fath, BM; Altaye, M; Muglia, LJ; DeFranco, EA; Ambalavanan, N; Parikh, NA. American Journal of Obstetrics and Gynecology. 2022.