Sascha R. A. Alles, PhD

It is estimated that 1 in 5 people suffer chronic pain globally. The goal of our work is to unravel molecular mechanisms of nociception and chronic pain in pre-clinical models and in human patients to help develop novel non-opioid treatments. The Alles Lab utilizes a combination of electrophysiological, imaging, behavioral, bioinformatic and molecular biology techniques with a particular focus on the physiology of neuronal circuits of the periphery, spinal cord, and brain. We aim to understand chronic pain mechanisms and develop new therapies for treatment. Current projects include the study of chemotherapy-induced peripheral neuropathy, chronic back pain, and trigeminal neuropathic pain.