Constitutive activation and oncogenicity are mediated by loss of helical structure at the cytosolic boundary of thrombopoietin receptor mutant dimers.
Defour, JP; Leroy, E; Dass, S; Balligand, T; Levy, G; Brett, IC; Papadopoulos, N; Mouton, C; Genet, L; Pecquet, C; Staerk, J; Smith, SO; Constantinescu, SN.
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