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A photo of Jose Cancelas Perez.

Director, Hoxworth Blood Center

Leader, Stem Cell Program

Incumbent, Beatrice C. Lampkin Endowment for Stem Cell and Hematotherapy

Professor, UC Department of Pediatrics



Biography & Affiliation

Clinical Interests

Hematopoietic stem cell proliferation and differentiation

Academic Affiliation

Professor, UC Department of Pediatrics


Experimental Hematology and Cancer Biology, Cancer and Blood Diseases, Global Health


MD: Autonomous University of Madrid, Spain, 1989.

Residency: Hematology and Hematotherapy, University of Alcala de Henares, Madrid, Spain, 1993.

PhD: Faculty of Medicine, University of Alcala de Henares, Madrid, Spain, 1996.


The signaling axis atypical protein kinase C lambda/iota-Satb2 mediates leukemic transformation of B-cell progenitors. Nayak, RC; Hegde, S; Althoff, MJ; Wellendorf, AM; Mohmoud, F; Perentesis, J; Reina-Campos, M; Reynaud, D; Zheng, Y; Diaz-Meco, MT; et al. Nature Communications. 2019; 10.

Ubiquitination is not omnipresent in myeloid leukemia. Nayak, RC; Cancelas, JA. Haematologica: the hematology journal. 2019; 104:1694-1696.

Neutrophils Derived from Genetically Modified Human Induced Pluripotent Stem Cells Circulate and Phagocytose Bacteria In Vivo. Trump, LR; Nayak, RC; Singh, AK; Emberesh, S; Wellendorf, AM; Lutzko, CM; Cancelas, JA. Stem Cells Translational Medicine. 2019; 8:557-567.

IODVA1, a Guanidinobenzimidazole Derivative with in vivo Activity Against Ras-Driven Cancer Models. Gasilina, A; Premnauth, G; Gurjar, P; Biesiada, J; Hegde, S; Milewski, D; Ma, G; Kalin, TV; Merino, E; Meller, J; et al. 2019.

Future of platelet formulations with improved clotting profile: a short review on human safety and efficacy data. Cancelas, JA. Transfusion. 2019; 59:1467-1473.

Twisting the bone marrow stem cell niche. Niu, H; Cancelas, JA. Haematologica: the hematology journal. 2018; 103:1937-1939.

Towards increasing shelf life and haemostatic potency of stored platelet concentrates. Hegde, S; Akbar, H; Zheng, Y; Cancelas, JA. Current Opinion in Hematology. 2018; 25:500-508.

Safety and efficacy of cryopreserved platelets in bleeding patients with thrombocytopenia. Slichter, SJ; Dumont, LJ; Cancelas, JA; Jones, M; Gernsheimer, TB; Szczepiorkowski, ZM; Dunbar, NM; Prakash, G; Medlin, S; Rugg, N; et al. Transfusion. 2018; 58:2129-2138.

Development, validation, and potential applications of biotinylated red blood cells for posttransfusion kinetics and other physiological studies: evidenced-based analysis and recommendations. Mock, DM; Nalbant, D; Kyosseva, SV; Schmidt, RL; An, G; Matthews, NI; Vlaar, AP J; van Bruggen, R; de Korte, D; Strauss, RG; et al. Transfusion. 2018; 58:2068-2081.

KLF5 controls glutathione metabolism to suppress p190-BCRABL+ B-cell lymphoblastic leukemia. Zhang, C; D'Alessandro, A; Wellendorf, AM; Mohmoud, F; Serrano-Lopez, J; Perentesis, JP; Komurov, K; Alexe, G; Stegmaier, K; Whitsett, JA; et al. Oncotarget. 2018; 9:29665-29679.