Blachy J. Dávila Saldaña, MD
- Physician, Division of Bone Marrow Transplantation and Immune Deficiency
- Associate Professor, UC Department of Pediatrics
- blachy.davilasaldana@cchmc.org
- Board Certified
About
Biography
I'm an immunologist specializing in stem cell transplants and patients with immune deficiency disorders. As a bone marrow transplant physician, I help provide new immune systems when medication alone cannot control infection or inflammation. I love caring for children while doing all I can to ensure they lead the most normal lives possible.
I've always been fascinated by the complexities of the immune system, and I knew this would be my interest early in my career. I went into medicine and quickly fell in love with pediatrics. I enjoy the deep connections forged with patients and families as we manage complex disorders together.
As a researcher, I'm working to reduce the intensity of stem cell transplants, so they are better tolerated. I also aim to improve our ability to help diagnose and manage patients with immune dysregulation. We work together with multiple organizations to increase our knowledge of these rare diseases so we may advocate for them.
When I'm not at work, I enjoy running, traveling with my partner, getting to know different cultures through food, and singing karaoke.
Undergraduate: University of Puerto Rico, Rio Piedras Campus, 1999-2003.
BS: General Sciences, summa cum Laude, class valedictorian.
Graduate/Medical: MD, University of Puerto Rico, Medical Sciences Campus, magna cum laude, 2003-2007.
Residency: Internal Medicine/Pediatrics, Rush University Medical Center, Chicago, IL, 2007-2011.
Fellowship:Pediatric Hematology / Oncology, Oregon Health & Science University, Portland, OR, 2011-2014.
Fellowship: Clinical Immunodeficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2014-2015.
Interests
Diagnosis, management, and treatment of non-malignant disorders, in particular patients with primary immune deficiency and immune regulatory disorders; combined immunodeficiency; bone marrow transplantation; stem cell therapy; long-term follow up
Services and Specialties
Insurance Information
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Publications
Perspectives on the current diagnostic and treatment paradigms in secondary hemophagocytic lymphohistiocytosis (HLH). Orphanet Journal of Rare Diseases. 2025; 20:200.
Addition of Thiotepa to Alemtuzumab, Fludarabine, and Melphalan Reduced-Intensity Conditioning Reduces Secondary Graft Failure in Allogeneic HSCT for Inborn Errors of Immunity. 2025; 1.
Reconstitution of Norovirus-Specific T-Cell Responses Following Hematopoietic Stem Cell Transplantation in Patients With Inborn Errors of Immunity and Chronic Norovirus Infection. The Journal of Infectious Diseases. 2025; 231:773-783.
Outcome Analysis Post Virus-Specific T Cell Therapy for the Treatment of Adenoviremia in Immunocompromised Pediatric Patients. Transplantation and Cellular Therapy. 2025; 31:s221-s222.
Emapalumab Treatment in Patients With Rheumatologic Disease-Associated Hemophagocytic Lymphohistiocytosis in the United States: A Retrospective Medical Chart Review Study. Arthritis and Rheumatology. 2025; 77:226-238.
Multiomics dissection of human RAG deficiency reveals distinctive patterns of immune dysregulation but a common inflammatory signature. Science immunology. 2025; 10:eadq1697.
Antiviral cellular therapy for enhancing T-cell reconstitution before or after hematopoietic stem cell transplantation (ACES): a two-arm, open label phase II interventional trial of pediatric patients with risk factor assessment. Nature Communications. 2024; 15:3258.
Pediatric lymphoproliferative disorders associated with inborn errors of immunity. Clinical Immunology. 2024; 266:110332.
Real-world treatment patterns and outcomes in patients with primary hemophagocytic lymphohistiocytosis treated with emapalumab. Blood Advances. 2024; 8:2248-2258.
73 Reconstitution of norovirus-specific T cell responses following hematopoetic stem cell transplantation in patients with inborn errors of immunity and chronic norovirus infection. Clinical Immunology. 2024; 262:110015.
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