A photo of James D. Gulick.

James D. Gulick, MS

  • Instructor, UC Department of Pediatrics



A high-throughput screening identifies ZNF418 as a novel regulator of the ubiquitin-proteasome system and autophagy-lysosomal pathway. Singh, SR; Meyer-Jens, M; Alizoti, E; Bacon, WC; Davis, G; Osinska, H; Gulick, J; Reischmann-Düsener, S; Orthey, E; McLendon, PM; et al. Autophagy. 2021; 17:3124-3139.

Ube2v1 Positively Regulates Protein Aggregation by Modulating Ubiquitin Proteasome System Performance Partially Through K63 Ubiquitination. Xu, N; Gulick, J; Osinska, H; Yu, Y; McLendon, PM; Shay-Winkler, K; Robbins, J; Yutzey, KE. Circulation Research. 2020; 126:907-922.

Myofibroblast-Specific TGFβ Receptor II Signaling in the Fibrotic Response to Cardiac Myosin Binding Protein C-Induced Cardiomyopathy. Meng, Q; Bhandary, B; Bhuiyan, MS; James, J; Osinska, H; Valiente-Alandi, I; Shay-Winkler, K; Gulick, J; Molkentin, JD; Blaxall, BC; et al. Circulation Research. 2018; 123:1285-1297.

Hypertrophic cardiomyopathy R403Q mutation in rabbit β-myosin reduces contractile function at the molecular and myofibrillar levels. Lowey, S; Bretton, V; Joel, PB; Trybus, KM; Gulick, J; Robbins, J; Kalganov, A; Cornachione, AS; Rassier, DE. Proceedings of the National Academy of Sciences of the United States of America. 2018; 115:11238-11243.

Cardiac Fibrosis in Proteotoxic Cardiac Disease is Dependent Upon Myofibroblast TGF -β Signaling. Bhandary, B; Meng, Q; James, J; Osinska, H; Gulick, J; Valiente-Alandi, I; Sargent, MA; Bhuiyan, S; Blaxall, BC; Molkentin, JD; et al. Journal of the American Heart Association. 2018; 7.

Abstract 265: TGF Beta Signaling and Fibrosis in cMyBP-C-dependent Cardiac Disease. Meng, Q; Bhandary, B; Osinska, H; James, J; Shay-Winkler, K; Gulick, J; McNamara, J; Bhuiyan, MS; Sadayappan, S; Robbins, J. Circulation Research. 2018; 123.