James D. Gulick, MS

A high-throughput screening identifies ZNF418 as a novel regulator of the ubiquitin-proteasome system and autophagy-lysosomal pathway. Singh, SR; Meyer-Jens, M; Alizoti, E; Bacon, WC; Davis, G; Osinska, H; Gulick, J; Reischmann-Düsener, S; Orthey, E; Mclendon, PM; Molkentin, JD; Schlossarek, S; Robbins, J; Carrier, L. Autophagy. 2021; 17(10):3124-3139.

Ube2v1 Positively Regulates Protein Aggregation by Modulating Ubiquitin Proteasome System Performance Partially Through K63 Ubiquitination. Xu, N; Gulick, J; Osinska, H; Yu, Y; Mclendon, PM; Shay-Winkler, K; Robbins, J; Yutzey, KE. Circulation Research. 2020; 126(7):907-922.

Myofibroblast-Specific TGFβ Receptor II Signaling in the Fibrotic Response to Cardiac Myosin Binding Protein C-Induced Cardiomyopathy. Meng, Q; Bhandary, B; Bhuiyan, MS; James, J; Osinska, H; Valiente-Alandi, I; Shay-Winkler, K; Gulick, J; Molkentin, JD; Blaxall, BC; Robbins, J. Circulation Research. 2018; 123(12):1285-1297.

Hypertrophic cardiomyopathy R403Q mutation in rabbit β-myosin reduces contractile function at the molecular and myofibrillar levels. Lowey, S; Bretton, V; Joel, PB; Trybus, KM; Gulick, J; Robbins, J; Kalganov, A; Cornachione, AS; Rassier, DE. Proceedings of the National Academy of Sciences of the United States of America. 2018; 115(44):11238-11243.

Cardiac Fibrosis in Proteotoxic Cardiac Disease is Dependent Upon Myofibroblast TGF -β Signaling. Bhandary, B; Meng, Q; James, J; Osinska, H; Gulick, J; Valiente-Alandi, I; Sargent, MA; Bhuiyan, MS; Blaxall, BC; Molkentin, JD; Robbins, J. Journal of the American Heart Association. 2018; 7(20):e010013.

Abstract 265: TGF Beta Signaling and Fibrosis in cMyBP-C-dependent Cardiac Disease. Meng, Q; Bhandary, B; Osinska, H; James, J; Shay-Winkler, K; Gulick, J; Mcnamara, J; Bhuiyan, MS; Sadayappan, S; Robbins, J. Circulation Research. 2018; 123(Suppl_1).

MMI-0100 Inhibits Cardiac Fibrosis in a Mouse Model Overexpressing Cardiac Myosin Binding Protein C. Meng, Q; Bhandary, B; Osinska, H; James, J; Xu, N; Shay-Winkler, K; Gulick, J; Willis, MS; Lander, C; Robbins, J. Journal of the American Heart Association. 2017; 6(9).

An Unbiased High-Throughput Screen to Identify Novel Effectors That Impact on Cardiomyocyte Aggregate Levels. Mclendon, PM; Davis, G; Gulick, J; Singh, SR; Xu, N; Salomonis, N; Molkentin, JD; Robbins, J. Circulation Research. 2017; 121(6):604-616.

In vivo definition of cardiac myosin-binding protein C's critical interactions with myosin. Bhuiyan, MS; Mclendon, P; James, J; Osinska, H; Gulick, J; Bhandary, B; Lorenz, JN; Robbins, J. Pflugers Archiv European Journal of Physiology. 2016; 468(10):1685-1695.

UBC9-Mediated Sumoylation Favorably Impacts Cardiac Function in Compromised Hearts. Gupta, MK; Mclendon, PM; Gulick, J; James, J; Khalili, K; Robbins, J. Circulation Research. 2016; 118(12):1894-1905.