Myofibroblast-Specific TGF beta Receptor II Signaling in the Fibrotic Response to Cardiac Myosin Binding Protein C-Induced Cardiomyopathy.
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Hypertrophic cardiomyopathy R403Q mutation in rabbit beta-myosin reduces contractile function at the molecular and myofibrillar levels.
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Proceedings of the National Academy of Sciences of USA.
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Cardiac Fibrosis in Proteotoxic Cardiac Disease is Dependent Upon Myofibroblast TGF-beta Signaling.
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MMI-0100 Inhibits Cardiac Fibrosis in a Mouse Model Overexpressing Cardiac Myosin Binding Protein C.
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An Unbiased High-Throughput Screen to Identify Novel Effectors That Impact on Cardiomyocyte Aggregate Levels.
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In vivo definition of cardiac myosin-binding protein C's critical interactions with myosin.
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Pflügers Archiv European Journal of Physiology.
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UBC9-Mediated Sumoylation Favorably Impacts Cardiac Function in Compromised Hearts.
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Phosphorylation and calcium antagonistically tune myosin-binding protein C's structure and function.
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Proceedings of the National Academy of Sciences of USA.
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Myosin-binding protein C corrects an intrinsic inhomogeneity in cardiac excitation-contraction coupling.
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