A photo of John Harley.

Director, Center for Autoimmune Genomics and Etiology (CAGE)

Professor, UC Department of Pediatrics


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Biography & Affiliation

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Professor, UC Department of Pediatrics



Science Blog


CNV Association of Diverse Clinical Phenotypes from eMERGE reveals novel disease biology underlying cardiovascular disease. Glessner, JT; Li, J; Desai, A; Palmer, M; Kim, D; Lucas, AM; Chang, X; Connolly, JJ; Almogeura, B; Harley, JB; et al. International Journal of Cardiology. 2020; 298:107-113.

Epstein Barr virus nuclear antigen 1 (EBNA-1) peptides recognized by adult multiple sclerosis patient sera induce neurologic symptoms in a murine model. Jog, NR; McClain, MT; Heinlen, LD; Gross, T; Towner, R; Guthridge, JM; Axtell, RC; Pardo, G; Harley, JB; James, JA. Journal of Autoimmunity. 2020; 106:102332-102332.

GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network. Namjou, B; Lingren, T; Huang, Y; Parameswaran, S; Cobb, BL; Stanaway, IB; Connolly, JJ; Mentch, FD; Benoit, B; Niu, X; et al. BMC Medicine. 2019; 17.

Complete tracheal ring deformity a translational genomics approach to pathogenesis. Sinner, DI; Carey, B; Zgherea, D; Kaufman, KM; Leesman, L; Wood, RE; Rutter, MJ; de Alarcon, A; Elluru, RG; Harley, JB; et al. American Journal of Respiratory and Critical Care Medicine. 2019; 200:1267-1281.

Harmonizing Clinical Sequencing and Interpretation for the eMERGE III Network. Zouk, H; Venner, E; Muzny, DM; Lennon, NJ; Rehm, HL; Gibbs, RA; Walker, K; Gordon, AS; Bowser, M; Harden, MV; et al. The American Journal of Human Genetics. 2019; 105:588-605.

Association of Epstein-Barr virus serological reactivation with transitioning to systemic lupus erythematosus in at-risk individuals. Jog, NR; Young, KA; Munroe, ME; Harmon, MT; Guthridge, JM; Kelly, JA; Kamen, DL; Gilkeson, GS; Weisman, MH; Karp, DR; et al. Annals of the Rheumatic Diseases. 2019; 78:1235-1241.

Gender Differences in Demographic and Health Characteristics of the Million Veteran Program Cohort. Harrington, KM; Nguyen, XT; Song, RJ; Hannagan, K; Quaden, R; Gagnon, DR; Cho, K; Deen, JE; Muralidhar, S; O'Leary, TJ; et al. Women's Health Issues. 2019; 29 Suppl 1:S56-S66.

Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians. Molineros, JE; Looger, LL; Kim, K; Okada, Y; Terao, C; Sun, C; Zhou, XJ; Raj, P; Kochi, Y; Suzuki, A; et al. PLoS Genetics. 2019; 15:e1008092-e1008092.

Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients. James, JA; Chen, H; Young, KA; Bemis, EA; Seifert, J; Bourn, RL; Deane, KD; Demoruelle, MK; Feser, M; O'Dell, JR; et al. EBioMedicine. 2019; 42:76-85.

Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis. Kottyan, LC; Maddox, A; Braxton, JR; Stucke, EM; Mukkada, V; Putnam, PE; Abonia, JP; Chehade, M; Wood, RA; Pesek, RD; et al. Genes and Immunity. 2019; 20:281-292.