A photo of Helen N. Jones.

Head of Research, Center for Fetal and Placental Research

Assistant Professor, UC Department of Surgery



Biography & Affiliation

Research Interests

Placental development and function; targeting the placenta for in utero treatments of pathological pregnancies; the placenta in congenital heart defects; the maternal-fetal interface in placental accreta spectrum

Academic Affiliation

Assistant Professor, UC Department of Surgery

Research Divisions

General and Thoracic Surgery

Blog Posts


BSc: University of St. Andrews, Scotland, 2000.

PhD: Rowett Research Institute, University of Aberdeen, Scotland, 2005.


Nanoparticle mediated increased insulin-like growth factor 1 expression enhances human placenta syncytium function. Wilson, RL; Owens, K; Sumser, EK; Fry, MV; Stephens, KK; Chuecos, M; Carrillo, M; Schlabritz-Loutsevitch, N; Jones, HN. Placenta. 2020; 93:1-7.

Eutherian-Specific Gene TRIML2 Attenuates Inflammation in the Evolution of Placentation. Zhang, X; Pavlicev, M; Jones, H; Muglia, L. Molecular Biology and Evolution. 2020; 37:507-523.

Intracisternal BioGlue injection in the fetal lamb: a novel model for creation of obstructive congenital hydrocephalus without additional chemically induced neuroinflammation. Oria, M; Duru, S; Scorletti, F; Vuletin, F; Encinas, JL; Correa-Martin, L; Bakri, K; Jones, HN; Sanchez-Margallo, FM; Peiro, JL. Journal of Neurosurgery: Pediatrics. 2019; 1-11.

Unique transcriptomic landscapes identified in idiopathic spontaneous and infection related preterm births compared to normal term births. Brockway, HM; Kallapur, SG; Buhimschi, IA; Buhimschi, CS; Ackerman, WE; Muglia, LJ; Jones, HN. PLoS ONE. 2019; 14.

Gab3 is required for IL-2- and IL-15-induced NK cell expansion and limits trophoblast invasion during pregnancy. Sliz, A; Locker, KC S; Lampe, K; Godarova, A; Plas, DR; Janssen, EM; Jones, H; Herr, AB; Hoebe, K. Science Immunology. 2019; 4.

Anthropoid primate-specific retroviral element THE1B controls expression of CRH in placenta and alters gestation length. Dunn-Fletcher, CE; Muglia, LM; Pavlicev, M; Wolf, G; Sun, M; Hu, Y; Huffman, E; Tumukuntala, S; Thiele, K; Mukherjee, A; et al. PLoS Biology. 2018; 16.

The Role of Abnormal Placentation in Congenital Heart Disease; Cause, Correlate, or Consequence?. Courtney, JA; Cnota, JF; Jones, HN. Frontiers in Physiology. 2018; 9.

Studies in genetically modified mice implicate maternal HDL as a mediator of fetal growth. Rebholz, SL; Melchior, JT; Davidson, WS; Jones, HN; Welge, JA; Prentice, AM; Moore, SE; Woollett, LA. FASEB Journal. 2018; 32:717-727.

Inverted formin 2 regulates intracellular trafficking, placentation, and pregnancy outcome. Lamm, KY B; Johnson, ML; Phillips, JB; Muntifering, MB; James, JM; Jones, HN; Redline, RW; Rokas, A; Muglia, LJ. eLife. 2018; 7.

Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface. Pavlicev, M; Wagner, GP; Chavan, AR; Owens, K; Maziarz, J; Dunn-Fletcher, C; Kallapur, SG; Muglia, L; Jones, H. PCR Methods and Applications. 2017; 27:349-361.