BSc: Co-major in genetics and biochemistry, University of Melbourne, Australia, 1984 (with honors).
PhD: University of Melbourne, Australia, at the Ludwig Institute for Cancer Research under Drs. AR Dunn and TJ Gonda, 1988.
Postdoctoral Fellow: The G.W. Hooper Research Foundation, University of California, San Francisco under Dr. JM Bishop, 1989-92. Studied the role of the macrophage in developmentally programmed tissue remodeling.
Wnt ligands in tumorigenesis; vascular regression and tissue regeneration; lens induction and morphogenesis.
Ophthalmology, Developmental Biology
Violet light suppresses lens-induced myopia via neuropsin (OPN5) in mice. Proceedings of the National Academy of Sciences of USA. 2021; 118:e2018840118.
Violet-light suppression of thermogenesis by opsin 5 hypothalamic neurons. Nature. 2020; 585:420-425.
Adaptive Thermogenesis in Mice Is Enhanced by Opsin 3-Dependent Adipocyte Light Sensing. Cell Reports. 2020; 30:672-686.e8.
Neuropsin (OPN5) Mediates Local Light-Dependent Induction of Circadian Clock Genes and Circadian Photoentrainment in Exposed Murine Skin. Current Biology. 2019; 29:3478-3487.e4.
An opsin 5-dopamine pathway mediates light-dependent vascular development in the eye. Nature Cell Biology. 2019; 21:420-429.
A direct and melanopsin-dependent fetal light response regulates mouse eye development. Nature. 2013; 494:243-246.
Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia. Proceedings of the National Academy of Sciences of USA. 2011; 108:18289-18294.
Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells. Nature. 2011; 474:511-515.
Macrophage Wnt7b is critical for kidney repair and regeneration. Proceedings of the National Academy of Sciences of USA. 2010; 107:4194-4199.
WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature. Nature. 2005; 437:417-421.
Richard A. Lang, PhD, James M. Greenberg, MD ...8/3/2021
Richard A. Lang, PhD5/24/2021
Richard A. Lang, PhD9/2/2020
Richard A. Lang, PhD1/21/2020
Richard A. Lang, PhD10/17/2019