A photo of James M. Greenberg.

Co-Director, Perinatal Institute

Director, Division of Neonatology

Professor, UC Department of Pediatrics



Board Certified

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My Biography & Research


Dr. Greenberg is a nationally recognized leader in neonatal-perinatal medicine. He serves as director of the Division of Neonatology for Cincinnati Children's Hospital Medical Center leading one of the largest comprehensive clinical and academic programs for newborn care in the United States. Dr. Greenberg has been division director since 2003, and has been an active clinician, researcher and teacher at Cincinnati Children's Hospital Medical Center for more than 22 years. In 2009, he was appointed associate director of the Perinatal Institute at Cincinnati Children’s and became co-director in 2011.

His research activities include developmental biology of the lung, neonatal chronic lung disease, neonatal epidemiology, and prevention of preterm birth. Dr. Greenberg partners with Cincinnati Children's faculty and regional leaders to lead community health initiatives to reduce preterm birth and eliminate infant mortality. He has authored more than 30 original research articles; and six book chapters in the textbook of Pediatrics, Maternal-Fetal Medicine, and Pulmonology.

As medical director for Regional Newborn Services and division director, Dr. Greenberg led the dramatic growth of the neonatology clinical program from 12 faculty physicians providing care at two neonatal intensive care units (NICUs) to more than 50 physicians providing newborn care at 13 regional hospitals including the five NICUs. The Division of Neonatology now has over 120,000 patient encounters per year. In addition to caring for all of the Level III and Level II intensive care nursery patients in the region, division physicians also see more than 18,000 normal newborns every year. The Newborn Intensive Care at Cincinnati Children’s represents the hub of the neonatology clinical program. This NICU has over 750 admissions per year and focuses its activities on caring for infants with complex medical and surgical problems. All patients requiring surgery, surgical subspecialty care, complex radiographic imaging, or comprehensive diagnostic services are managed at the Cincinnati Children's Hospital Medical Center NICU.

In addition to the clinical program, the Division of Neonatology has an active research program. The division is one of the 22 NICHD Neonatal Research Network Centers. Extramural grant funding for the division in fiscal year 2015 was in excess of $10 million. Division research programs span basic, translational, and clinical endeavors.

The division also has an active quality improvement program focusing on outcomes in varied clinical settings ranging from improving reliability of delivery room thermal stability to reduction of central-line-associated blood stream infections in the NICU.

Clinical Interests

Neonatal chronic lung disease; late preterm infant

Academic Affiliation

Professor, UC Department of Pediatrics


Newborn Intensive Care NICU, Perinatal, Pulmonary Biology, Prevention of Preterm Birth, Neonatology

Science Blog

How to Save Babies? Find Every Mother


How to Save Babies? Find Every Mother

James M. Greenberg, MD, Robert S. Kahn, MD, MPH7/1/2019

My Education

MD: University of Illinois College of Medicine, Chicago, IL, 1977-1981.

Pediatric Internship and Residency: University of Minnesota Hospital and Clinic, Minneapolis, MN, 1981-1984. Chief Resident, Department of Pediatrics, University of Minnesota Hospital and Clinic, Minneapolis, MN, 1984.

Fellowship: Immunology/Neonatology, University of Minnesota Hospital and Clinic, Minneapolis, MN, 1985-1987; 1988-1989; visiting scientist, Medical Research Council Laboratory of Molecular Biology, Division of Protein and Nucleic Acid Chemistry, Cambridge, England.

Certification: American Board of Pediatrics, 1988; subspecialty board, Neonatal/Perinatal Medicine, 1989.

My Publications

Respiratory medication use in extremely premature (<29 weeks) infants during initial NICU hospitalization: Results from the prematurity and respiratory outcomes program. Greenberg, JM; Poindexter, BB; Shaw, PA; Bellamy, SL; Keller, RL; Moore, PE; McPherson, C; Ryan, RM. Pediatric Pulmonology. 2020; 55:360-368.

Respiratory Medications in Infants < 29 Weeks during the First Year Postdischarge: The Prematurity and Respiratory Outcomes Program (PROP) Consortium. Ryan, RM; Keller, RL; Poindexter, BB; D'Angio, CT; Shaw, PA; Bellamy, SL; Moore, PE; McPherson, C; Greenberg, JM; Chougnet, C; et al. The Journal of Pediatrics. 2019; 208:148-155.e3.

Black Race Is Associated with a Lower Risk of Bronchopulmonary Dysplasia. Ryan, RM; Feng, R; Bazacliu, C; Ferkol, TW; Ren, CL; Mariani, TJ; Poindexter, BB; Wang, F; Moore, PE; Chougnet, C; et al. The Journal of Pediatrics. 2019; 207:130-135.e2.

Material community deprivation and hospital utilization during the first year of life: an urban population-based cohort study. Brokamp, C; Beck, AF; Goyal, NK; Ryan, P; Greenberg, JM; Hall, ES. Annals of Epidemiology. 2019; 30:37-43.

Surveillance of Intrauterine Opioid Exposures Using Electronic Health Records. Hall, ES; Wexelblatt, SL; Greenberg, JM. Population Health Management. 2018; 21:486-492.

Exome sequencing identifies gene variants and networks associated with extreme respiratory outcomes following preterm birth. Hamvas, A; Feng, R; Bi, Y; Wang, F; Bhattacharya, S; Mereness, J; Kaushal, M; Cotten, CM; Ballard, PL; Mariani, TJ; et al. BMC Genetics. 2018; 19.

Tidal Breathing Measurements at Discharge and Clinical Outcomes in Extremely Low Gestational Age Neonates. Ren, CL; Feng, R; Davis, SD; Eichenwald, E; Jobe, A; Moore, PE; Panitch, HB; Sharp, JK; Kisling, J; Clem, C; et al. Annals of the American Thoracic Society. 2018; 15:1311-1319.

Acute Responses to Diuretic Therapy in Extremely Low Gestational Age Newborns: Results from the Prematurity and Respiratory Outcomes Program Cohort Study. Blaisdell, CJ; Troendle, J; Zajicek, A; Chougnet, C; Greenberg, JM; Hardie, W; Jobe, AH; McDowell, K; Ferkol, T; Holland, MR; et al. The Journal of Pediatrics. 2018; 197:42-47.e1.

Implementation of a Regional Perinatal Data Repository from Clinical and Billing Records. Hall, ES; Greenberg, JM; Muglia, LJ; Divekar, P; Zahner, J; Gholap, J; Leonard, M; Marsolo, K. Maternal and Child Health Journal. 2018; 22:485-493.

Evaluation of identifier field agreement in linked neonatal records. Hall, ES; Marsolo, K; Greenberg, JM. Journal of Perinatology. 2017; 37:969-974.