I am an immunologist with a long-standing interest in innate immune regulation and cell biology. Over the past 20 years, I’ve conducted research in both the US and Europe, and in 2025, I relocated my lab to Cincinnati Children’s.
Our lab studies how innate immune responses are regulated at the cellular level to prevent overactivation. When these responses go unchecked, they can lead to chronic inflammation and contribute to autoimmune or autoinflammatory diseases. We focus on two key families of innate immune receptors, Toll-like receptors and inflammasomes, and explore how their activities are influenced by their location and movement within immune cells.
By uncovering the inner workings of these receptors, we aim to develop new strategies to prevent harmful immune activation and contribute to better treatments for inflammatory diseases.
PhD: University of Vienna, Max Perutz Laboratories, Vienna, Austria, 2012.
Postdoc: University of California, Berkeley, CA, 2019.
Postdoc: Free University of Berlin, Germany, 2020.
Research Group Leader: Max Planck Institute for Infection Biology, Berlin, Germany, 2025.
Immunobiology