A photo of S. Steven Potter.

Professor, UC Department of Pediatrics

513-636-4850

513-636-4317

Biography & Affiliation

Research Interests

Kidney development and disease; Hox genes; craniofacial development; creation of an atlas of global gene expression patterns in the multiple compartments of the developing kidney; analysis of perturbed gene expression patterns in the kidney glomeruli of patients with focal segmental glomerulosclerosis; craniofacial development using mutant mice, laser capture microdissection, next generation sequencing, and microarrays; recombineering to target multiple Hox genes at once

Academic Affiliation

Professor, UC Department of Pediatrics

Departments

Developmental Biology, Fibrosis

Education

BA: University of California, Los Angeles (UCLA), CA, 1971.

PhD: University of North Carolina, Chapel Hill, NC, 1976.

Postdoctoral Fellowship: Harvard Medical School, Boston, MA, 1976-1978.

Publications

Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse. Zhang, L; He, X; Liu, X; Zhang, F; Huang, LF; Potter, AS; Xu, L; Zhou, W; Zheng, T; Luo, Z; et al. Cancer Cell. 2019; 36:302-318.e7.

A bigenic mouse model of FSGS reveals perturbed pathways in podocytes, mesangial cells and endothelial cells. Potter, AS; Drake, K; Brunskill, EW; Potter, SS. PLoS ONE. 2019; 14:e0216261-e0216261.

Maturation of heart valve cell populations during postnatal remodeling. Hulin, A; Hortells, L; Gomez-Stallons, MV; O'Donnell, A; Chetal, K; Adam, M; Lancellotti, P; Oury, C; Potter, SS; Salomonis, N; et al. Development (Cambridge). 2019; 146:dev173047-dev173047.

Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis. Weng, Q; Wang, J; Wang, J; He, D; Cheng, Z; Zhang, F; Verma, R; Xu, L; Dong, X; Liao, Y; et al. Cell Stem Cell. 2019; 24:707-723.e8.

The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution. Taylor, DM; Aronow, BJ; Tan, K; Bernt, K; Salomonis, N; Greene, CS; Frolova, A; Henrickson, SE; Wells, A; Pei, L; et al. Developmental Cell. 2019; 49:10-29.

Hedgehog signaling patterns the oral-aboral axis of the mandibular arch. Xu, J; Liu, H; Lan, Y; Adam, M; Clouthier, DE; Potter, S; Jiang, R. eLife. 2019; 8.

Dissociation of Tissues for Single-Cell Analysis. Potter, AS; Steven Potter, S. Methods in Molecular Biology. : Springer New York; Springer New York; 2019.

Disruption of Hox9,10,11 function results in cellular level lineage infidelity in the kidney. Drake, KA; Adam, M; Mahoney, R; Potter, SS. Scientific Reports. 2018; 8.

Single-cell RNA sequencing for the study of development, physiology and disease. Potter, SS. Nature Reviews Nephrology. 2018; 14:479-492.

Hnf4a deletion in the mouse kidney phenocopies Fanconi renotubular syndrome. Marable, SS; Chung, E; Adam, M; Potter, SS; Park, J. JCI insight. 2018; 3.