A photo of Michael Taylor.

Michael D. Taylor, MD, PhD


  • Director, Advanced Imaging Innovation
  • Professor, UC Department of Pediatrics
Our research is focused on determining whether changes in the properties of heart muscle — as imaged by cardiac magnetic resonance (MR) — can provide accurate diagnosis and important prognosis for pediatric cardiology patients.

About

Biography

I have always been fascinated by the potential of modern engineering, physics and technology for solving complicated problems. Specifically, I’m interested in applying these tools to diagnose and treat cardiac disease.

I trained in physics during medical school and my work in graduate school included studies of how the heart muscle uses glucose both in health and disease. I believe our ability to determine properties of the cell using noninvasive imaging techniques is one of the most fascinating advances in medicine.

At Cincinnati Children’s, I serve as director of Advanced Imaging Innovation within the Heart Institute. I am also part of the Cincinnati Children’s Imaging Research Center.

Our research is focused on determining whether changes in the properties of heart muscle — as imaged by cardiac magnetic resonance (MR) — can provide accurate diagnosis and important prognosis for pediatric cardiology patients. We have ongoing studies that include Duchenne muscular dystrophy, heart transplantation, single ventricle and myocarditis patients. We have also studied the changes in heart muscle in sickle cell disease and bone marrow transplant patients.

My clinical focus is noninvasive imaging of congenital and acquired heart disease. I am interested in cardiac MR, computed tomography and positron emission tomography.

Publications

Selected

Repeated intravenous cardiosphere-derived cell therapy in late-stage Duchenne muscular dystrophy (HOPE-2): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial. McDonald, CM; Marbán, E; Hendrix, S; Hogan, N; Ruckdeschel Smith, R; Eagle, M; Finkel, RS; Tian, C; Janas, J; Harmelink, MM; et al. The Lancet. 2022; 399:1049-1058.

Selected

The Effect of Adiposity on Cardiovascular Function and Myocardial Fibrosis in Patients With Duchenne Muscular Dystrophy. Henson, SE; Lang, SM; Khoury, PR; Tian, C; Rutter, MM; Urbina, EM; Ryan, TD; Taylor, MD; Alsaied, T. Journal of the American Heart Association. 2021; 10.

Selected

Non-invasive left ventricular myocardial work indices in healthy adolescents at rest. Tretter, JT; Pradhan, S; Truong, VT; Mullikin, A; Mazur, W; Hill, GD; Redington, AN; Taylor, MD. International Journal of Cardiovascular Imaging. 2021; 37:2429-2438.

Selected

Rapid cardiac MRI protocol for cardiac assessment in paediatric and young adult patients undergoing haematopoietic stem cell transplant: a feasibility study. Ryan, TD; Moore, RA; Lang, SM; Khoury, P; Dandoy, CE; Davies, SM; Taylor, MD. Cardiology in the Young. 2021; 31:973-978.

Selected

Variations in native T1 values in patients with Duchenne muscular dystrophy with and without late gadolinium enhancement. Lang, SM; Alsaied, T; Khoury, PR; Ryan, TD; Taylor, MD. International Journal of Cardiovascular Imaging. 2021; 37:635-642.

Selected

Breath-hold and free-breathing quantitative assessment of biventricular volume and function using compressed SENSE: a clinical validation in children and young adults. Kocaoglu, M; Pednekar, AS; Wang, H; Alsaied, T; Taylor, MD; Rattan, MS. Journal of Cardiovascular Magnetic Resonance. 2020; 22.

Selected

Left Ventricular Magnetic Resonance Imaging Strain Predicts the Onset of Duchenne Muscular Dystrophy-Associated Cardiomyopathy. Siddiqui, S; Alsaied, T; Henson, SE; Gandhi, J; Patel, P; Khoury, P; Villa, C; Ryan, TD; Wittekind, SG; Lang, SM; et al. Circulation: Cardiovascular Imaging. 2020; 13.

Selected

mDixon ECG-gated 3-dimensional cardiovascular magnetic resonance angiography in patients with congenital cardiovascular disease. Kourtidou, S; Jones, MR; Moore, RA; Tretter, JT; Ollberding, NJ; Crotty, EJ; Rattan, MS; Fleck, RJ; Taylor, MD. Journal of Cardiovascular Magnetic Resonance. 2019; 21.

Selected

Conservative gadolinium administration to patients with Duchenne muscular dystrophy: decreasing exposure, cost, and time, without change in medical management. Lang, SM; Alsaied, T; Moore, RA; Rattan, M; Ryan, TD; Taylor, MD. International Journal of Cardiovascular Imaging. 2019; 35:2213-2219.

Selected

Can virtual heart transplantation via 3-dimensional imaging increase the maximum acceptable donor size?. Szugye, NA; Lorts, A; Zafar, F; Taylor, M; Morales, DL S; Moore, RA. Journal of Heart Transplantation. 2019; 38:331-333.

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