A photo of Sherry Thornton.

Field Service Professor, UC Department of Pediatrics

513-636-1318

513-636-3328

Biography & Affiliation

Biography

I am a developmental and cell biologist who has spent over 20 years involved in research to determine the mechanisms underlying the pathogenesis of arthritis. My colleagues and I seek to determine the cells types that are associated with this condition.

I acquired a keen interest in the mechanisms of disease development when I was in graduate school, and I applied these mechanisms to gene therapy for arthritis as a postdoctoral fellow in the laboratory of Dr. Raphael Hirsch in the Division of Rheumatology at Cincinnati Children’s.

I joined the faculty in the Division of Rheumatology in 2002. In 2008, I became the director of the Research Flow Cytometry Core, a shared resource laboratory that provides the Cincinnati research community with a central location for flow cytometry instrumentation, training and education.

My research specifically involves the analysis of mechanisms underlying the pathogenesis of arthritis and specifically the determination of cell types important in subtypes of juvenile idiopathic arthritis.

I have a passion for mentoring and career development. As director of the Summer Undergraduate Research Fellowship Program at Cincinnati Children’s, I mentor undergraduate students to provide them with a foundation for making career choices in the biomedical sciences.

Research Interests

Evaluating targets for the treatment of rheumatic disease; angiogenesis; animal models of arthritis

Academic Affiliation

Field Service Professor, UC Department of Pediatrics

Research Divisions

Rheumatology

Education

BS: Ball State University, Muncie, IN.

PhD: University of Cincinnati, College of Medicine, Cincinnati, OH.

Postdoctoral Research Fellow: Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

Publications

Biosafety during a pandemic: shared resource laboratories rise to the challenge. Aspland, AM; Douagi, I; Filby, A; Jellison, ER; Martinez, L; Shinko, D; Smith, AL; Tang, VA; Thornton, S. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2021; 99:68-80.

Remote Training of SRL Users and Staff in a Global Pandemic. Daniels, K; Conway, A; Gardner, R; Martinez, L; Price, KM; Schneider, S; Sheridan, R; Srivastava, J; Thornton, S. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2021; 99:42-50.

Evaluating the Effects of Cell Sorting on Gene Expression. Box, A; Delay, M; Tighe, S; Chittur, SV; Bergeron, A; Cochran, M; Lopez, P; Meyer, EM; Saluk, A; Thornton, S; et al. Journal of Biomolecular Techniques. 2020.

Evaluating the Effects of Cell Sorting on Gene Expression. Box, A; DeLay, M; Tighe, S; Chittur, SV; Bergeron, A; Cochran, M; Lopez, P; Meyer, EM; Saluk, A; Thornton, S; et al. Journal of Biomolecular Techniques. 2020; 31:100-111.

Single cell sorting - a survey of practices. Brundage, K; Abshari, M; Adams, D; Bispo, C; Bowen, S; Cochran, M; Harley, R; Hassel, C; Heyward, F; Kollipara, A; et al. Journal of Biomolecular Techniques. 2020; 31.

S100 Proteins, Cytokines, and Chemokines as Tear Biomarkers in Children with Juvenile Idiopathic Arthritis-associated Uveitis. Angeles-Han, ST; Miraldi Utz, V; Thornton, S; Schulert, G; Rodriguez-Smith, J; Kauffman, A; Sproles, A; Mwase, N; Hennard, T; Grom, A; et al. Ocular Immunology and Inflammation. 2020; 1-5.

FCRG - Fixation and Sorting for RNA. Loof, N; Mehrnoosh, A; Bergeron, A; Saluk, A; Box, A; Brundage, K; Adams, D; Dwyer, K; Meyer, E; Cochran, M; et al. Journal of Biomolecular Techniques. 2019; 30.

A Multiparameter Flow Cytometry Analysis Panel to Assess CD163 mRNA and Protein in Monocyte and Macrophage Populations in Hyperinflammatory Diseases. Thornton, S; Tan, R; Sproles, A; Do, T; Schick, J; Grom, AA; DeLay, M; Schulert, GS. Journal of Immunology. 2019; 202:1635-1643.

Discovery of SERPINA3 as a candidate urinary biomarker of lupus nephritis activity. Turnier, JL; Brunner, HI; Bennett, M; Aleed, A; Gulati, G; Haffey, WD; Thornton, S; Wagner, M; Devarajan, P; Witte, D; et al. Rheumatology. 2019; 58:321-330.

Discovery of tear biomarkers in children with chronic non-infectious anterior uveitis: a pilot study. Angeles-Han, ST; Yeh, S; Patel, P; Duong, D; Jenkins, K; Rouster-Stevens, KA; Altaye, M; Fall, N; Thornton, S; Prahalad, S; et al. Journal of Ophthalmic Inflammation and Infection. 2018; 8.