Coronavirus (COVID-19) Information

Coronavirus (COVID-19) Vaccines | Third Dose for Immunocompromised People

Pfizer Third Dose for Immunocompromised People

The Centers for Disease Control and Prevention recommends that you get an additional dose of COVID-19 vaccine if:

  • Your immune system is moderately to severely compromised
  • You received a two-dose series of mRNA vaccine (Pfizer or Moderna)

We encourage you to talk to your doctor about whether you need this third shot. The CDC recommends that your third dose be the same vaccine as your first two doses.

You can get a third dose of the Pfizer vaccine at Cincinnati Children’s.

Walk-ins are welcome, or you can make appointments. Locations and dates are:

  • Burnet Campus | Wednesdays, 4:30 pm – 7:30 pm, and Saturdays, 8 am – 11:30 am
  • Liberty Campus | Mondays and Thursdays, 4:30 pm – 7:30 pm
  • Green Township Neighborhood Location | Tuesdays, 4:30 pm – 7:30 pm

Additional dates:

  • Sept. 2, 4:30 pm-7:30 pm, Burnet Campus
  • Sept. 7, 4:30 pm-7:30 pm, Liberty Campus
  • Sept. 9, 4:30 pm-7:30 pm, Burnet Campus

Holiday closings: 

  • Clinics will be closed Saturday, Sept. 4, at Burnet, and Monday, Sept. 6, at Liberty, in observance of Labor Day.

Click the “Request Appointment” button to get started.

Make an Appointment


Do I need to bring my vaccine card with me?

Yes, you need to bring your vaccine card with you.

What if I don’t have my card?

If you did not receive your vaccine from Cincinnati Children’s and misplaced your card, you can contact the vaccine provider and request a replacement.

When should I get a third dose?

An immunocompromised patient can receive their third dose 28 days after their second shot.

Is this third dose the same as a booster shot?

No. This additional dose is intended to improve immunocompromised people’s response to their initial vaccine series. It is not the same as a booster dose, which is given to people when the immune response to a primary vaccine series is likely to have waned over time. 

Read More about the CDC Recommendations

Topics include: What You Need to Know | Data on Decreased Immune Response Among Immunocompromised People | Who Needs an Additional COVID-19 Vaccine? | Frequently Asked Questions

Vaccine Clinic Locations

Burnet Campus.

Burnet Campus: Go to the Sabin Auditorium in the Location D building on the first floor.



Liberty Campus. 

Liberty Campus: Enter the main drive and proceed until you get to the stop sign. Turn right and follow signs to the “Surgery” entrance. You will be on the back (I-75) side of the building. Walk to the first entrance you come to on the left side. Someone will direct you once inside the building.

Green Township.

Green Township: Turn into the main driveway from Harrison Avenue. Proceed past the entrance to the upper parking lot and drive down the hill to the lower parking lot entrance on your left. Walk into the building entrance and someone will direct you once inside the building.


Find Other COVID-19 Vaccine Providers

Here are other resources for the Greater Cincinnati area:

Contact Us to Cancel or Reschedule

Contact us.

If you need to cancel or reschedule your Pfizer COVID-19 vaccine appointment at Cincinnati Children's, call us at 513-517-1100 during business hours:

  • Monday-Friday: 7:30 am-5 pm

Letting us know that you won't be showing up for your appointment helps Cincinnati Children's to provide vaccine to more people.

Emotional or Behavioral Support

resources and support

If you are scheduled for a COVID-19 vaccine at Cincinnati Children’s and need emotional or behavioral support, call us at 513-636-6989.