Best of Our Research

Publications

Proper, SP; Dwyer, AT; Appiagyei, A; Felton, JM; Ben-Baruch Morgenstern, N; Marlman, JM; Kotliar, M; Barski, A; Troutman, TD; Rothenberg, ME; et al. Aryl hydrocarbon receptor and IL-13 signaling crosstalk in human keratinocytes and atopic dermatitis. Frontiers in Allergy. 2024; 5:1323405.

Mahoney, M; Damalanka, VC; Tartell, MA; Chung, DH; Lourenço, AL; Pwee, D; Mayer Bridwell, AE; Hoffmann, M; Voss, J; Karmakar, P; et al. A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells. Proceedings of the National Academy of Sciences of USA. 2021; 118:e2108728118.

Proper, SP; Azouz, NP; Mersha, TB. Achieving Precision Medicine in Allergic Disease: Progress and Challenges. Frontiers in Immunology. 2021; 12:720746.

Rochman, M; Xie, YM; Mack, L; Caldwell, JM; Klingler, AM; Osswald, GA; Azouz, NP; Rothenberg, ME. Broad transcriptional response of the human esophageal epithelium to proton pump inhibitors. Journal of Allergy and Clinical Immunology. 2021; 147:1924-1935.

Azouz, NP; Klingler, AM; Callahan, V; Akhrymuk, IV; Elez, K; Raich, L; Henry, BM; Benoit, JL; Benoit, SW; Noé, F; et al. Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2-Priming Protease TMPRSS2. Pathogens and Immunity. 2021; 6:55-74.

Hempel, T; Raich, L; Olsson, S; Azouz, NP; Klingler, AM; Hoffmann, M; Pöhlmann, S; Rothenberg, ME; Noé, F. Molecular mechanism of inhibiting the SARS-CoV-2 cell entry facilitator TMPRSS2 with camostat and nafamostat. Chemical Science. 2021; 12:983-992.

Klein, O; Azouz, NP; Sagi-Eisenberg, R. Measurement of Exocytosis in Genetically Manipulated Mast Cells. Methods in molecular biology (Clifton, N.J.). 2021; 2233:181-192.

Brusilovsky, M; Rochman, M; Azouz, NP; Mack, LE; Rothenberg, ME. Uncovering the secretes of allergic inflammation. The Journal of Clinical Investigation. 2020; 130:3419-3421.

Azouz, NP; Klingler, AM; Pathre, P; Besse, JA; Ben Baruch-Morgenstern, N; Ballaban, AY; Osswald, GA; Brusilovsky, M; Habel, JE; Caldwell, JM; et al. Functional role of kallikrein 5 and proteinase-activated receptor 2 in eosinophilic esophagitis. Science Translational Medicine. 2020; 12:eaaz7773.

Oliva, S; Azouz, NP; Stronati, L; Rothenberg, ME. Recent advances in potential targets for eosinophilic esophagitis treatments. Expert Review of Clinical Immunology. 2020; 16:421-428.

Bitton, A; Avlas, S; Reichman, H; Itan, M; Karo-Atar, D; Azouz, NP; Rozenberg, P; Diesendruck, Y; Nahary, L; Rothenberg, ME; et al. A key role for IL-13 signaling via the type 2 IL-4 receptor in experimental atopic dermatitis. Science Immunology. 2020; 5:eaaw2938.

Azouz, NP; Rothenberg, ME. Mechanisms of gastrointestinal allergic disorders. The Journal of Clinical Investigation. 2019; 129:1419-1430.