Best of Our Research

Publications

Kliewer, KL; Murray-Petzold, C; Collins, MH; Abonia, JP; Bolton, SM; DiTommaso, LA; Martin, LJ; Zhang, X; Mukkada, VA; Putnam, PE; et al. Benralizumab for eosinophilic gastritis: a single-site, randomised, double-blind, placebo-controlled, phase 2 trial. The Lancet Gastroenterology and Hepatology. 2023; 8:803-815.

Kliewer, KL; Gonsalves, N; Dellon, ES; Katzka, DA; Abonia, JP; Aceves, SS; Arva, NC; Besse, JA; Bonis, PA; Caldwell, JM; et al. One-food versus six-food elimination diet therapy for the treatment of eosinophilic oesophagitis: a multicentre, randomised, open-label trial. The Lancet Gastroenterology and Hepatology. 2023; 8:408-421.

Shoda, T; Rochman, M; Collins, MH; Caldwell, JM; Mack, LE; Osswald, GA; Mukkada, VA; Putnam, PE; Rothenberg, ME. Molecular analysis of duodenal eosinophilia. Journal of Allergy and Clinical Immunology. 2023; 151:1027-1039.

Zhang, S; Shoda, T; Aceves, SS; Arva, NC; Chehade, M; Collins, MH; Dellon, ES; Falk, GW; Gonsalves, N; Gupta, SK; et al. Mast cell-pain connection in eosinophilic esophagitis. Allergy: European Journal of Allergy and Clinical Immunology. 2022; 77:1895-1899.

Shoda, T; Collins, MH; Rochman, M; Wen, T; Caldwell, JM; Mack, LE; Osswald, GA; Besse, JA; Haberman, Y; Aceves, SS; et al. Evaluating Eosinophilic Colitis as a Unique Disease Using Colonic Molecular Profiles: A Multi-Site Study. Gastroenterology. 2022; 162:1635-1649.

Min, S; Shoda, T; Wen, T; Rothenberg, ME. Diagnostic merits of the Eosinophilic Esophagitis Diagnostic Panel from a single esophageal biopsy. Journal of Allergy and Clinical Immunology. 2022; 149:782-787.e1.

Shoda, T; Wen, T; Caldwell, JM; Ben-Baruch Morgenstern, N; Osswald, GA; Rochman, M; Mack, LE; Felton, JM; Abonia, JP; Arva, NC; et al. Loss of Endothelial TSPAN12 Promotes Fibrostenotic Eosinophilic Esophagitis via Endothelial Cell-Fibroblast Crosstalk. Gastroenterology. 2022; 162:439-453.

Shoda, T; Kaufman, KM; Wen, T; Caldwell, JM; Osswald, GA; Purnima, P; Zimmermann, N; Collins, MH; Rehn, K; Foote, H; et al. Desmoplakin and periplakin genetically and functionally contribute to eosinophilic esophagitis. Nature Communications. 2021; 12:6795.

Shoda, T; Wen, T; Caldwell, JM; Collins, MH; Besse, JA; Osswald, GA; Abonia, JP; Arva, NC; MDd, DA; Capocelli, KE; et al. Molecular, endoscopic, histologic, and circulating biomarker-based diagnosis of eosinophilic gastritis: Multi-site study. Journal of Allergy and Clinical Immunology. 2020; 145:255-269.

Shoda, T; Wen, T; Aceves, SS; Abonia, JP; Atkins, D; Bonis, PA; Caldwell, JM; Capocelli, KE; Carpenter, CL; Collins, MH; et al. Eosinophilic oesophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross-sectional study. The Lancet Gastroenterology and Hepatology. 2018; 3:477-488.

Rochman, M; Rochman, Y; Caldwell, JM; Mack, LE; Besse, JA; Manes, NP; Yoon, SH; Shoda, T; Nita-Lazar, A; Rothenberg, ME. The minichromosome maintenance complex drives esophageal basal zone hyperplasia. JCI insight. 2023; 8:e172143.

Kliewer, KL; Murray-Petzold, C; Collins, MH; Abonia, JP; Bolton, SM; DiTommaso, LA; Martin, LJ; Zhang, X; Mukkada, VA; Putnam, PE; et al. Benralizumab for eosinophilic gastritis: a single-site, randomised, double-blind, placebo-controlled, phase 2 trial. The Lancet Gastroenterology and Hepatology. 2023; 8:803-815.

Gonsalves, N; Doerfler, B; Zalewski, A; Yang, GY; Martin, LJ; Zhang, X; Shoda, T; Brusilovsky, M; Aceves, S; Thompson, K; et al. Prospective study of an amino acid-based elemental diet in an eosinophilic gastritis and gastroenteritis nutrition trial. Journal of Allergy and Clinical Immunology. 2023; 152:676-688.

Aknin, E; Larey, A; Caldwell, JM; Collins, MH; Rothenberg, ME; Savir, Y. (2023) Harnessing Digital Pathology And Causal Learning To Improve Eosinophilic Esophagitis Dietary Treatment Assignment. Institute of Electrical and Electronics Engineers (IEEE). 00:1-8.

Ben-Baruch Morgenstern, N; Shoda, T; Rochman, Y; Caldwell, JM; Collins, MH; Mukkada, V; Putnam, PE; Bolton, SM; Felton, JM; Rochman, M; et al. Local type 2 immunity in eosinophilic gastritis. Journal of Allergy and Clinical Immunology. 2023; 152:136-144.

Kliewer, KL; Gonsalves, N; Dellon, ES; Katzka, DA; Abonia, JP; Aceves, SS; Arva, NC; Besse, JA; Bonis, PA; Caldwell, JM; et al. One-food versus six-food elimination diet therapy for the treatment of eosinophilic oesophagitis: a multicentre, randomised, open-label trial. The Lancet Gastroenterology and Hepatology. 2023; 8:408-421.

Brusilovsky, M; Rochman, M; Shoda, T; Kotliar, M; Caldwell, JM; Mack, LE; Besse, JA; Chen, X; Weirauch, MT; Barski, A; et al. Vitamin D receptor and STAT6 interactome governs oesophageal epithelial barrier responses to IL-13 signalling. Gut. 2023; 72:834-845.

Sato, H; Osonoi, K; Sharlin, CS; Shoda, T. Genetic and Molecular Contributors in Eosinophilic Esophagitis. Current Allergy and Asthma Reports. 2023; 23:255-266.

Shoda, T; Rochman, M; Collins, MH; Caldwell, JM; Mack, LE; Osswald, GA; Mukkada, VA; Putnam, PE; Rothenberg, ME. Molecular analysis of duodenal eosinophilia. Journal of Allergy and Clinical Immunology. 2023; 151:1027-1039.

Alvarado, D; Lu, Y; Shoda, T; Caldwell, JM; Keler, T; Rothenberg, ME. Strong association of mast cells with eosinophilic esophagitis-specific signatures. Allergy: European Journal of Allergy and Clinical Immunology. 2023; 78:583-586.

Avlas, S; Shani, G; Rhone, N; Itan, M; Dolitzky, A; Hazut, I; Grisaru-Tal, S; Gordon, Y; Shoda, T; Ballaban, A; et al. Epithelial cell-expressed type II IL-4 receptor mediates eosinophilic esophagitis. Allergy: European Journal of Allergy and Clinical Immunology. 2023; 78:464-476.

Ben-Baruch Morgenstern, N; Ballaban, AY; Wen, T; Shoda, T; Caldwell, JM; Kliewer, K; Felton, JM; Abonia, JP; Mukkada, VA; Putnam, PE; et al. Single-cell RNA sequencing of mast cells in eosinophilic esophagitis reveals heterogeneity, local proliferation, and activation that persists in remission. Journal of Allergy and Clinical Immunology. 2022; 149:2062-2077.

Zhang, S; Shoda, T; Aceves, SS; Arva, NC; Chehade, M; Collins, MH; Dellon, ES; Falk, GW; Gonsalves, N; Gupta, SK; et al. Mast cell-pain connection in eosinophilic esophagitis. Allergy: European Journal of Allergy and Clinical Immunology. 2022; 77:1895-1899.

Shoda, T; Collins, MH; Rochman, M; Wen, T; Caldwell, JM; Mack, LE; Osswald, GA; Besse, JA; Haberman, Y; Aceves, SS; et al. Evaluating Eosinophilic Colitis as a Unique Disease Using Colonic Molecular Profiles: A Multi-Site Study. Gastroenterology. 2022; 162:1635-1649.

Hirano, I; Collins, MH; King, E; Sun, Q; Chehade, M; Abonia, JP; Bonis, PA; Capocelli, KE; Dellon, ES; Falk, GW; et al. Prospective Endoscopic Activity Assessment for Eosinophilic Gastritis in a Multisite Cohort. The American Journal of Gastroenterology (Elsevier). 2022; 117:413-423.

Min, S; Shoda, T; Wen, T; Rothenberg, ME. Diagnostic merits of the Eosinophilic Esophagitis Diagnostic Panel from a single esophageal biopsy. Journal of Allergy and Clinical Immunology. 2022; 149:782-787.e1.

Shoda, T; Wen, T; Caldwell, JM; Ben-Baruch Morgenstern, N; Osswald, GA; Rochman, M; Mack, LE; Felton, JM; Abonia, JP; Arva, NC; et al. Loss of Endothelial TSPAN12 Promotes Fibrostenotic Eosinophilic Esophagitis via Endothelial Cell-Fibroblast Crosstalk. Gastroenterology. 2022; 162:439-453.

Shoda, T; Kaufman, KM; Wen, T; Caldwell, JM; Osswald, GA; Purnima, P; Zimmermann, N; Collins, MH; Rehn, K; Foote, H; et al. Desmoplakin and periplakin genetically and functionally contribute to eosinophilic esophagitis. Nature Communications. 2021; 12:6795.

Chiang, AW T; Duong, LD; Shoda, T; Nhu, QM; Ruffner, M; Hara, T; Aaron, B; Joplin, E; Manresa, MC; Abonia, JP; et al. Type 2 Immunity and Age Modify Gene Expression of Coronavirus-induced Disease 2019 Receptors in Eosinophilic Gastrointestinal Disorders. Journal of Pediatric Gastroenterology and Nutrition. 2021; 72:718-722.

Lyles, JL; Martin, LJ; Shoda, T; Collins, MH; Trimarchi, MP; He, H; Kottyan, LC; Mukkada, VA; Rothenberg, ME. Very early onset eosinophilic esophagitis is common, responds to standard therapy, and demonstrates enrichment for CAPN14 genetic variants. Journal of Allergy and Clinical Immunology. 2021; 147:244-254.e6.

O'Shea, KM; Rochman, M; Shoda, T; Zimmermann, N; Caldwell, J; Rothenberg, ME. Eosinophilic esophagitis with extremely high esophageal eosinophil counts. Journal of Allergy and Clinical Immunology. 2021; 147:409-412.e5.

Emi-Sugie, M; Shoda, T; Futamura, K; Takeda, T; Ainai, A; Hasegawa, H; Saito, H; Matsumoto, K; Matsuda, A. Robust production of IL-33 and TSLP by lung endothelial cells in response to low-dose dsRNA stimulation. Journal of Allergy and Clinical Immunology. 2020; 146:1449-1452.e2.

Yang, L; Yamamoto-Hanada, K; Ishitsuka, K; Ayabe, T; Mezawa, H; Konishi, M; Shoda, T; Sago, H; Saito, H; Ohya, Y; et al. Medical and surgical complications in pregnancy and obstetric labour complications in the Japan Environment and Children's Study (JECS) cohort: a birth cohort study. Journal of Obstetrics and Gynaecology. 2020; 40:918-924.

Dunn, JL M; Shoda, T; Caldwell, JM; Wen, T; Aceves, SS; Collins, MH; Dellon, ES; Falk, GW; Leung, J; Martin, LJ; et al. Esophageal type 2 cytokine expression heterogeneity in eosinophilic esophagitis in a multisite cohort. Journal of Allergy and Clinical Immunology. 2020; 145:1629-1640.e4.

Shoda, T; Wen, T; Caldwell, JM; Collins, MH; Besse, JA; Osswald, GA; Abonia, JP; Arva, NC; MDd, DA; Capocelli, KE; et al. Molecular, endoscopic, histologic, and circulating biomarker-based diagnosis of eosinophilic gastritis: Multi-site study. Journal of Allergy and Clinical Immunology. 2020; 145:255-269.

Kurten, RC; Rawson, R; Shoda, T; Duong, LD; Adejumobi, D; Levy, R; Newbury, RO; Rothenberg, ME; Akuthota, P; Wright, BL; et al. Development and Application of a Functional Human Esophageal Mucosa Explant Platform to Eosinophilic Esophagitis. Scientific Reports. 2019; 9:6206.

Yamaji, N; Lopes, KD S; Shoda, T; Ishitsuka, K; Kobayashi, T; Ota, E; Mori, R. TNF-α blockers for the treatment of Kawasaki disease in children. Cochrane database of systematic reviews (Online). 2019; 8:CD012448.

Ben Baruch-Morgenstern, N; Shoda, T; Rothenberg, ME. Bagels and LOX in patients with eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2019; 144:41-43.