Dissecting maternal and fetal genetic effects underlying the associations between maternal phenotypes, birth outcomes, and adult phenotypes: A mendelian-randomization and haplotype-based genetic score analysis in 10,734 mother-infant pairs. Editor, Tekola-Ayele F. PLoS Medicine. 2020; 17:e1003305.
.Novel phenotype-disease matching tool for rare genetic diseases. Genetics in Medicine. 2019; 21:339-346.
.Genome-wide signatures of transcription factor activity: connecting transcription factors, disease, and small molecules. Editor, Morris Q. PLoS Computational Biology. 2013; 9:e1003198.
.Disease candidate gene identification and prioritization using protein interaction networks. BMC Bioinformatics. 2009; 10:73.
.ToppGene Suite for gene list enrichment analysis and candidate gene prioritization. Nucleic Acids Research (NAR). 2009; 37:W305-W311.
.Improved human disease candidate gene prioritization using mouse phenotype. BMC Bioinformatics. 2007; 8:392.
.A novel method for cell deconvolution using DNA methylation in PCA space. BMC Genomics. 2024; 25:798.
.Probiotic bacteria-released extracellular vesicles enhance macrophage phagocytosis in polymicrobial sepsis by activating the FPR1/2 pathway. Molecular medicine (Cambridge, Mass.). 2024; 30:216.
.2024; 23:a017.
. Abstract A017: IGF2BP1 is essential for ETO2/GLIS2 leukemogenesis via stabilization of primitive myeloid transcriptional programs. Molecular Cancer Therapeutics.2024; 150:a4118360.
. Abstract 4118360: Lipocalin10 is Critical for Macrophage Efferocytosis to Repair Myocardial Ischemia/Reperfusion Injury. Circulation.Estimating prevalence of rare genetic disease diagnoses using electronic health records in a children's hospital. Human Genetics and Genomics Advances. 2024; 5:100341.
.Macrophage-enriched Sectm1a promotes efficient efferocytosis to attenuate ischemia/reperfusion-induced cardiac injury. JCI insight. 2024; 9:e173832.
.Association of maternal prenatal copper concentration with gestational duration and preterm birth: a multicountry meta-analysis. American Journal of Clinical Nutrition. 2024; 119:221-231.
.A functional mechanism for a non-coding variant near AGTR2 associated with risk for preterm birth. BMC Medicine. 2023; 21:258.
.Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth. Nature Genetics. 2023; 55:1807-1819.
.Lipocalin 10 is essential for protection against inflammation-triggered vascular leakage by activating LDL receptor-related protein 2-slingshot homologue 1 signalling pathway. Cardiovascular Research (CVR). 2023; 119:1981-1996.
.Identification of a heterogeneous and dynamic ciliome during embryonic development and cell differentiation. Development (Cambridge). 2023; 150:dev201237.
.Genetic effects on the timing of parturition and links to fetal birth weight. Nature Genetics. 2023; 55:559-567.
.2022; 140:3431-3432.
. In Vivo Crispr Screening Identifies Novel Vulnerabilities in ETO2/GLIS2-rearranged Leukemia. Blood.Using deep learning and electronic health records to detect Noonan syndrome in pediatric patients. Genetics in Medicine. 2022; 24:2329-2337.
.Prevalence of Genetic Diagnoses in a Cohort With Valvar Pulmonary Stenosis. Circulation: Genomic and Precision Medicine. 2022; 15:e003635.
.Loss of Lipocalin 10 Exacerbates Diabetes-Induced Cardiomyopathy via Disruption of Nr4a1-Mediated Anti-Inflammatory Response in Macrophages. Frontiers in Immunology. 2022; 13:930397.
.2022; 2022.05.16.22275164.
. Interrogating the causal effects of maternal circulating CRP on gestational duration and birth weight.2022; 42:a386.
. Abstract 386: Lipocalin 10 Protects Against Sepsis-triggered Vascular Leakage Through Activation Of The Ssh1-cofilin Signaling Pathway. Arteriosclerosis, Thrombosis, and Vascular Biology.2022; 2022.01.31.478534.
. PDX models of relapsed pediatric AML preserve global gene expression patterns and reveal therapeutic targets.The Exosome-Associated Tetraspanin CD63 Contributes to the Efficient Assembly and Infectivity of the Hepatitis B Virus. Hepatology Communications. 2021; 5:1238-1251.
.Synergistic metalloproteinase-based remodeling of matrix by pancreatic tumor and stromal cells. Editor, Zech T. PloS one. 2021; 16:e0248111.
.Sectm1a Facilitates Protection against Inflammation-Induced Organ Damage through Promoting TRM Self-Renewal. Molecular Therapy. 2021; 29:1294-1311.
.Sectm1a deficiency aggravates inflammation-triggered cardiac dysfunction through disruption of LXRα signalling in macrophages. Cardiovascular Research (CVR). 2021; 117:890-902.
.DNA-Damage-Induced Alternative Splicing of p53. Cancers. 2021; 13:E251.
.Dissecting maternal and fetal genetic effects underlying the associations between maternal phenotypes, birth outcomes, and adult phenotypes: A mendelian-randomization and haplotype-based genetic score analysis in 10,734 mother-infant pairs. Editor, Tekola-Ayele F. PLoS Medicine. 2020; 17:e1003305.
.Maturation of Lipophagic Organelles in Hepatocytes Is Dependent Upon a Rab10/Dynamin-2 Complex. Hepatology. 2020; 72:486-502.
.The small GTPase Rab32 resides on lysosomes to regulate mTORC1 signaling. Journal of Cell Science. 2020; 133:jcs236661.
.2020; 2020.05.12.079863.
. Haplotype-based analysis distinguishes maternal-fetal genetic contribution to pregnancy-related outcomes.Tsg101 positively regulates P62-Keap1-Nrf2 pathway to protect hearts against oxidative damage. Redox Biology. 2020; 32:101453.
.Dynamin 2 interacts with α-actinin 4 to drive tumor cell invasion. Editor, Parent C. Molecular Biology of the Cell. 2020; 31:439-451.
.The anti-viral dynamin family member MxB participates in mitochondrial integrity. Nature Communications. 2020; 11:1048.
.