Xue Lab

Publications

Sun, S; Zheng, Y; Kim, YS; Zhong, Z; Kobayashi, N; Xue, X; Liu, Y; Zhou, Z; Xu, Y; Zhai, J; Wang, H; Fu, J. A transgene-free, human peri-gastrulation embryo model presents trilaminar embryonic disc-, amnion- and yolk sac-like structures. Nature Cell Biology. 2026.

Xue, X; Rahman, OM; Sun, S; Bok, J; Tang, A; Fu, J. Generation of spatially patterned human neural tube-like structures using microfluidic gradient devices. Nature Protocols. 2026; 21(4):1730-1753.

Bok, J; Kim, YS; Cheng, F; Gao, C; Zhou, Z; Kobayashi, N; Sun, S; Tang, A; Xue, X; Nguyen, DH; Li, P; Fu, J. A controllable human spinal cord model with full dorsoventral patterning. Nature Communications. 2026.

Nunley, H; Xue, X; Fu, J; Lubensky, DK. Generation of fate patterns via intercellular forces. Physical Review Research. 2025; 7(2):l022051.

Xue, X; Liu, Y; Fu, J. Bioengineering embryo models. Nature Reviews Bioengineering. 2025; 3(1):11-29.

Liu, Y; Kim, YS; Xue, X; Miao, Y; Kobayashi, N; Sun, S; Yan, RZ; Yang, Q; Pourquié, O; Fu, J. A human pluripotent stem cell-based somitogenesis model using microfluidics. Cell Stem Cell. 2024; 31(8):1113-1126.e6.

Li, W; Guo, J; Hobson, EC; Xue, X; Li, Q; Fu, J; Deng, CX; Guo, Z. Metabolic‐Glycoengineering‐Enabled Molecularly Specific Acoustic Tweezing Cytometry for Targeted Mechanical Stimulation of Cell Surface Sialoglycans. Angewandte Chemie International Edition. 2024; 136(20).

Xue, X; Kim, YS; Ponce-Arias, A-I; O'laughlin, R; Yan, RZ; Kobayashi, N; Tshuva, RY; Tsai, Y-H; Sun, S; Zheng, Y; Song, H; Ming, G-L; Reiner, O; Fu, J. A patterned human neural tube model using microfluidic gradients. Nature. 2024; 628(8007):391-399.

Esfahani, SN; Zheng, Y; Arabpour, A; Irizarry, AMR; Kobayashi, N; Xue, X; Shao, Y; Zhao, C; Agranonik, NL; Sparrow, M; Yang, R; Chien, KR; Clark, AT; Fu, J. Derivation of human primordial germ cell-like cells in an embryonic-like culture. Nature Communications. 2024; 15(1):167.

Liu, Y; Xue, X; Sun, S; Kobayashi, N; Kim, YS; Fu, J. Morphogenesis beyond in vivo. Nature Reviews Physics. 2024; 6(1):28-44.

Xu, Z; Liu, S; Xue, X; Li, W; Fu, J; Deng, CX. Rapid responses of human pluripotent stem cells to cyclic mechanical strains applied to integrin by acoustic tweezing cytometry. Scientific Reports. 2023; 13(1):18030.

Sun, S; Xue, X; Fu, J. Modeling development using microfluidics: bridging gaps to foster fundamental and translational research. Current Opinion in Genetics and Development. 2023; 82:102097.

Zheng, Y; Yan, RZ; Sun, S; Kobayashi, M; Xiang, L; Yang, R; Goedel, A; Kang, Y; Xue, X; Esfahani, SN; Chien, KR; Li, T; Shioda, T; Fu, J. Single-cell analysis of embryoids reveals lineage diversification roadmaps of early human development. Cell Stem Cell. 2022; 29(9):1402-1419.e8.

Li, Z; Lin, F; Zhong, C-H; Wang, S; Xue, X; Shao, Y. Single-Cell Sequencing to Unveil the Mystery of Embryonic Development. Advanced Biology. 2022; 6(2):e2101151.