Way Lab

Publications

Zhang, X; Mcginnis, CS; Yu, G; Chen, S; Zheng, P; Schürch, CM; Hiam-Galvez, KJ; Reticker-Flynn, NE; Guo, W; Yao, W; Way, SS; Malissen, B; Strober, S; Engleman, EG. Erythropoietin receptor on cDC1s dictates immune tolerance. Nature. 2025.

Almodallal, Y; Whitehurst, D; Way, SS; Koo, J; Kumar, AR. Emapalumab for Maladaptive Interferon-γ-Mediated Inflammation in Drug Reaction With Eosinophilia and Systemic Symptoms Complicating First-Line Antituberculosis Therapy. Pediatric Blood and Cancer. 2025; 72(12):e32052.

Chua, KJ; Quilang, RC; Sallinger, K; Aktipis, CA; Arck, P; Bianchi, DW; Chang, H-D; Cleaves, HJ; Eikmans, M; Fjeldstad, HES; Wilson, MA; Ye, J; Kroneis, T; Boddy, AM. Identifying Key Questions and Challenges in Microchimerism Biology. Advanced Science. 2025; 12(48):e14969.

Presicce, P; Beckman, D; Cappelletti, M; Vu, A; Ott, S; Diniz, G; Jobe, A; Chougnet, C; Divanovic, S; Way, SSY; Morrison, J; Kallapur, S. Intrauterine infection causes neuroinflammation and a selective loss of immature neurons in preterm non-human primate (NHP) fetuses 3227. Journal of Immunology. 2025; 214(Supplement_1).

Peng, Y; Pham, G; Sun, J; Adhikari, U; Kumar, S; Shao, T-Y; Kinder, JM; Turner, LH; Way, SS. Tolerance to non-inherited maternal antigen is sustained by LysM+ CD11c+ maternal microchimeric cells. Immunity. 2025; 58(9):2176-2189.e3.

Stevens, J; Culberson, E; Kinder, J; Ramiriqui, A; Gray, J; Bonfield, M; Shao, T-Y; Al Gharaibeh, F; Peterson, L; Steinmeyer, S; Sengupta, S; Alenghat, T; Way, SS; Deshmukh, H. Microbiota-derived inosine programs protective CD8+ T cell responses against influenza in newborns. Cell. 2025; 188(16):4239-4256.e19.

Deshmukh, H; Whitsett, J; Zacharias, W; Way, SS; Martinez, FD; Mizgerd, J; Pryhuber, G; Ambalavanan, N; Bacharier, L; Natarajan, A; Randolph, A; Nino, G; Mejias, A; Ramilo, O. Impact of Viral Lower Respiratory Tract Infection (LRTI) in Early Childhood (0-2 Years) on Lung Growth and Development and Lifelong Trajectories of Pulmonary Health: A National Institutes of Health (NIH) Workshop Summary. Pediatric Pulmonology. 2025; 60(1):e27357.

Miller-Handley, H; Harper, G; Pham, G; Turner, LH; Shao, T-Y; Russi, AE; Erickson, JJ; Ford, ML; Araki, K; Way, SS. Immune suppression sustained allograft acceptance requires PD1 inhibition of CD8+ T cells. Journal of Immunology. 2025; 214(1):192-198.

Pham, G; Diep, RE; Turner, LH; Haslam, DB; Way, SS. Complement-producing maternal microchimeric cells override infection susceptibility in complement-deficient murine offspring. Journal of Clinical Investigation. 2024; 135(1).

Koleva, P; He, J; Dunsmore, G; Bozorgmehr, N; Lu, J; Huynh, M; Tollenaar, S; Huang, V; Walter, J; Way, SS; Elahi, S. CD71 + erythroid cells promote intestinal symbiotic microbial communities in pregnancy and neonatal period. Microbiome. 2024; 12(1):142.

Detomaso, A; Kim, H; Shauh, J; Adulla, A; Zigo, S; Ghoul, M; Presicce, P; Kallapur, SG; Goodman, W; Tilburgs, T; Way, S-S; Hackney, D; Moore, J; Mesiano, S. Progesterone inactivation in decidual stromal cells: A mechanism for inflammation-induced parturition. Proceedings of the National Academy of Sciences of the United States of America. 2024; 121(25):e2400601121.

Russi, A; Shao, T-Y; Nguyen, A; Way, SS. 912 MICROBIOTA DRIVEN INTESTINAL INFLAMMATION AVERTED BY IL10 PRODUCING KRUPPEL-LIKE FACTOR 2 CD4+ T CELLS. Gastroenterology. 2024; 166(5):s-221-s-222.

Wu, Q; Zhang, J; Kumar, S; Shen, S; Kincaid, M; Johnson, CB; Zhang, YS; Turcotte, R; Alt, C; Ito, K; Ito, K; Way, SS; Kofron, JM; Lucas, D. Resilient anatomy and local plasticity of naive and stress haematopoiesis. Nature. 2024; 627(8005):839-846.

Pham, G; Shao, T-Y; Kinder, JM; Peng, Y; Turner, LH; Way, SS. Pregnancy induced displacement of preexisting microchimeric cells in the absence of maternal B and T cells. Frontiers in Immunology. 2024; 15:1478465.

Abu-Raya, B; Esser, MJ; Nakabembe, E; Reiné, J; Amaral, K; Diks, AM; Imede, E; Way, SS; Harandi, AM; Gorringe, A; Le Doare, K; Halperin, SA; Berkowska, MA; Sadarangani, M. Antibody and B-cell Immune Responses Against Bordetella Pertussis Following Infection and Immunization. Journal of Molecular Biology. 2023; 435(24):168344.

Shao, T-Y; Jiang, TT; Stevens, J; Russi, AE; Troutman, TD; Bernieh, A; Pham, G; Erickson, JJ; Eshleman, EM; Alenghat, T; Weaver, CT; Haslam, DB; Deshmukh, H; Way, SS. Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation. Cell reports. 2023; 42(11):113323.

Shao, T-Y; Kinder, JM; Harper, G; Pham, G; Peng, Y; Liu, J; Gregory, EJ; Sherman, BE; Wu, Y; Iten, AE; Hu, Y-C; Russi, AE; Erickson, JJ; Miller-Handley, H; Way, SS. Reproductive outcomes after pregnancy-induced displacement of preexisting microchimeric cells. Science. 2023; 381(6664):1324-1330.

Giles, ML; Way, SS; Marchant, A; Aghaepour, N; James, T; Schaltz-Buchholzer, F; Zazara, D; Arck, P; Kollmann, TR. Maternal Vaccination to Prevent Adverse Pregnancy Outcomes: An Underutilized Molecular Immunological Intervention? Journal of Molecular Biology. 2023; 435(13):168097.

Eshleman, EM; Shao, T-Y; Woo, V; Rice, T; Engleman, L; Didriksen, BJ; Whitt, J; Haslam, DB; Way, SS; Alenghat, T. Intestinal epithelial HDAC3 and MHC class II coordinate microbiota-specific immunity. Journal of Clinical Investigation. 2023; 133(4).

Shao, T-Y; Haslam, DB; Bennett, RJ; Way, SS. Friendly fungi: symbiosis with commensal Candida albicans. Trends in Immunology. 2022; 43(9):706-717.

Severance, AL; Kinder, JM; Xin, L; Burg, AR; Shao, T-Y; Pham, G; Tilburgs, T; Goodman, WA; Mesiano, S; Way, SS. Maternal-fetal conflict averted by progesterone- induced FOXP3+ regulatory T cells. iScience. 2022; 25(6):104400.

Erickson, JJ; Archer-Hartmann, S; Yarawsky, AE; Miller, JLC; Seveau, S; Shao, T-Y; Severance, AL; Miller-Handley, H; Wu, Y; Pham, G; Lau, JTY; Azadi, P; Herr, AB; Way, SS. Pregnancy enables antibody protection against intracellular infection. Nature. 2022; 606(7915):769-775.

Shao, T-Y; Kakade, P; Witchley, JN; Frazer, C; Murray, KL; Ene, IV; Haslam, DB; Hagan, T; Noble, SM; Bennett, RJ; Way, SS. Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity. Cell reports. 2022; 39(7):110837.

Eshleman, EM; Shao, T-Y; Woo, V; Rice, T; Whitt, J; Engleman, L; Way, SS; Alenghat, T. Epithelial MHC class II directs microbiota-specific intestinal immune homeostasis. Journal of Immunology. 2022; 208(Supplement_1):115.03-115.03.

Mcdaniel, MM; Chawla, AS; Jain, A; Meibers, HE; Saha, I; Gao, Y; Jain, V; Roskin, K; Way, SS; Pasare, C. Effector memory CD4+ T cells induce damaging innate inflammation and autoimmune pathology by engaging CD40 and TNFR on myeloid cells. Science immunology. 2022; 7(67):eabk0182.

Eshleman, EM; Shao, T-Y; Woo, V; Rice, T; Whitt, J; Engleman, L; Way, SS; Alenghat, T. Intestinal epithelial MHC class II regulation by HDAC3 instructs microbiota-specific CD4+ T cells. bioRxiv. 2022; 2022.01.01.473735.