Gilbert / Wu / Pedapati Lab Research

Goel, A; Cantu, DA; Guilfoyle, J; Chaudhari, GR; Newadkar, A; Todisco, B; de Alba, D; Kourdougli, N; Schmitt, LM; Pedapati, E; et al. Impaired perceptual learning in a mouse model of Fragile X syndrome is mediated by parvalbumin neuron dysfunction and is reversible. Nature Neuroscience. 2018; 21:1404-1411.

Tsetsos, F; Sul, JH; Illmann, C; Osiecki, L; Darrow, SM; Hirschtritt, ME; Greenberg, E; Muller-Vahl, KR; Stuhrmann, M; Dion, Y; et al. Synaptic processes and immune-related pathways implicated in Tourette syndrome. Translational Psychiatry. 2021; 11.

Smith, EG; Pedapati, EV; Liu, R; Schmitt, LM; Dominick, KC; Shaffer, RC; Sweeney, JA; Erickson, CA. Sex differences in resting EEG power in Fragile X Syndrome. Journal of Psychiatric Research. 2021; 138:89-95.

Harris, AD; Gilbert, DL; Horn, PS; Crocetti, D; Cecil, KM; Edden, RA E; Huddleston, DA; Mostofsky, SH; Puts, NA J. Relationship between GABA levels and task-dependent cortical excitability in children with attention-deficit/hyperactivity disorder. Electromyography and Clinical Neurophysiology. 2021; 132:1163-1172.

Zhang, Y; Abdulkadir, M; Deng, L; Fernandez, TV; Garcia-Delgar, B; Hagstrøm, J; Hoekstra, PJ; King, RA; Koesterich, J; Kuperman, S; et al. Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families. Molecular Psychiatry. 2021.

Detrick, JA; Zink, C; Rosch, KS; Horn, PS; Huddleston, DA; Crocetti, D; Wu, SW; Pedapati, EV; Wassermann, EM; Mostofsky, SH; et al. Motor cortex modulation and reward in children with attention-deficit/hyperactivity disorder. Brain Communications. 2021; 3.

Wink, LK; Reisinger, DL; Horn, P; Shaffer, RC; O'Brien, K; Schmitt, L; Dominick, KR; Pedapati, EV; Erickson, CA. Brief Report: Intranasal Ketamine in Adolescents and Young Adults with Autism Spectrum Disorder-Initial Results of a Randomized, Controlled, Crossover, Pilot Study. Journal of Autism and Developmental Disorders. 2021; 51:1392-1399.

Garris, JF; Huddleston, DA; Jackson, HS; Horn, PS; Gilbert, DL. Implementation of the Mini-Child Tourette Syndrome Impairment Scale: Relationships to Symptom Severity and Treatment Decisions. Journal of Child Neurology. 2021; 36:288-295.

Bruce, AB; Yuan, W; Gilbert, DL; Horn, PS; Jackson, HS; Huddleston, DA; Wu, SW. Altered frontal-mediated inhibition and white matter connectivity in pediatric chronic tic disorders. Experimental Brain Research. 2021; 239:955-965.

Zea Vera, A; Liu, W; Thomas, C; Gilbert, DL. Pearls & Oy-sters: A Novel Presentation of Ataxia With Vitamin E Deficiency Caused by TTPA Gene Mutation. Neurology. 2021; 96:e640-e642.

Miyakoshi, M; Schmitt, LM; Erickson, CA; Sweeney, JA; Pedapati, EV. Can We Push the "Quasi-Perfect Artifact Rejection " Even Closer to Perfection?. Frontiers in Neuroinformatics. 2021; 14.

Rossi, S; Antal, A; Bestmann, S; Bikson, M; Brewer, C; Brockmöller, J; Carpenter, LL; Cincotta, M; Chen, R; Daskalakis, JD; et al. Safety and recommendations for TMS use in healthy subjects and patient populations, with updates on training, ethical and regulatory issues: Expert Guidelines. Electromyography and Clinical Neurophysiology. 2021; 132:269-306.

Lamy, M; Pedapati, EV; Dominick, KL; Wink, LK; Erickson, CA. Recent Advances in the Pharmacological Management of Behavioral Disturbances Associated with Autism Spectrum Disorder in Children and Adolescents. Paediatric Drugs. 2020; 22:473-483.

Shillington, A; Pedapati, E; Hopkin, R; Suhrie, K. Early behavioral and developmental interventions in ADNP-syndrome: A case report of SWI/SNF-related neurodevelopmental syndrome. Molecular genetics & genomic medicine. 2020; 8.

Coffman, MC; Shaffer, RC; Schmitt, LM; Dominick, KC; Pedapati, E; Wang, A; Berry-Kravis, E; Tartaglia, N; Erickson, CA. Examination of Correlates to Health-Related Quality of Life in Individuals with Fragile X Syndrome. Brain Sciences. 2020; 10.

Fitzpatrick, SE; Schmitt, LM; Adams, R; Pedapati, EV; Wink, LK; Shaffer, RC; Sage, J; Weber, JD; Dominick, KC; Erickson, CA. Pediatric Quality of Life Inventory (PedsQL) in Fragile X Syndrome. Journal of Autism and Developmental Disorders. 2020; 50:1056-1063.

Reisinger, DL; Shaffer, RC; Horn, PS; Hong, MP; Pedapati, EV; Dominick, KC; Erickson, CA. Atypical Social Attention and Emotional Face Processing in Autism Spectrum Disorder: Insights From Face Scanning and Pupillometry. Frontiers in Integrative Neuroscience. 2020; 13.

Shaffer, RC; Schmitt, L; Thurman, AJ; Abbeduto, L; Hong, M; Pedapati, E; Dominick, K; Sweeney, J; Erickson, C. The Relationship between Expressive Language Sampling and Clinical Measures in Fragile X Syndrome and Typical Development. Brain Sciences. 2020; 10.

Schmitt, LM; Wang, J; Pedapati, EV; Thurman, AJ; Abbeduto, L; Erickson, CA; Sweeney, JA. A neurophysiological model of speech production deficits in fragile X syndrome. Brain Communications. 2020; 2.

Pedapati, EV; Mooney, LN; Wu, SW; Erickson, CA; Sweeney, JA; Shaffer, RC; Horn, PS; Wink, LK; Gilbert, DL. Motor cortex facilitation: a marker of attention deficit hyperactivity disorder co-occurrence in autism spectrum disorder. Translational Psychiatry. 2019; 9.

Scher, MS; Breningstall, G; Gilbert, D; Jordan, L; Khakoo, Y; LePichon, J. The 2018 Pediatric Neurology Trainee Publication Award. Pediatric Neurology. 2019; 101.

Feist, TB; Gilbert, DL. Program Administrator Burnout: More Than a Wellness Issue. Journal of graduate medical education. 2019; 11.

Hong, MP; Eckert, EM; Pedapati, EV; Shaffer, RC; Dominick, KC; Wink, LK; Sweeney, JA; Erickson, CA. Differentiating social preference and social anxiety phenotypes in fragile X syndrome using an eye gaze analysis: a pilot study. Journal of Neurodevelopmental Disorders. 2019; 11.

Eckert, EM; Dominick, KC; Pedapati, EV; Wink, LK; Shaffer, RC; Andrews, H; Choo, T; Chen, C; Kaufmann, WE; Tartaglia, N; et al. Pharmacologic Interventions for Irritability, Aggression, Agitation and Self-Injurious Behavior in Fragile X Syndrome: An Initial Cross-Sectional Analysis. Journal of Autism and Developmental Disorders. 2019; 49:4595-4602.

Ethridge, LE; De Stefano, LA; Schmitt, LM; Woodruff, NE; Brown, KL; Tran, M; Wang, J; Pedapati, EV; Erickson, CA; Sweeney, JA. Auditory EEG Biomarkers in Fragile X Syndrome: Clinical Relevance. Frontiers in Integrative Neuroscience. 2019; 13.

McLane, RD; Schmitt, LM; Pedapati, EV; Shaffer, RC; Dominick, KC; Horn, PS; Gross, C; Erickson, CA. Peripheral Amyloid Precursor Protein Derivative Expression in Fragile X Syndrome. Frontiers in Integrative Neuroscience. 2019; 13.

Gilbert, DL. Inflammation in Tic Disorders and Obsessive-Compulsive Disorder: Are PANS and PANDAS a Path Forward?. Journal of Child Neurology. 2019; 34:598-611.

Gilbert, DL; Huddleston, DA; Wu, SW; Pedapati, EV; Horn, PS; Hirabayashi, K; Crocetti, D; Wassermann, EM; Mostofsky, SH. Motor cortex inhibition and modulation in children with ADHD. Neurology. 2019; 93:e599-e610.

Gilbert, DL. Treatment of Tourette Syndrome: Medical Therapy. Therapy of Movement Disorders. 2019.

Yu, D; Sul, JH; Tsetsos, F; Nawaz, MS; Huang, AY; Zelaya, I; Illmann, C; Osiecki, L; Darrow, SM; Hirschtritt, ME; et al. Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies. American Journal of Psychiatry. 2019; 176:217-227.

Wu, S; Pedapati, E; Roeckner, A; Huddleston, D; Jackson, H; Gilbert, D. Decreased functional connectivity between frontal and motor cortex in Tourette Syndrome. Brain Stimulation. 2019; 12.

Gilbert, D; Wu, S; Horn, P; Pedapati, E; Mostofsky, S. Reduced motor cortex modulation during response inhibition task correlates with worse performance more severe clinical and motor impairment in children with ADHD. Brain Stimulation. 2019; 12.

Pedapati, E; Mooney, L; Wu, S; Sweeney, J; Erickson, C; Gilbert, D. Motor Cortex Facilitation: An inattention marker in ADHD co-occurrence in Autism Spectrum Disorder. Brain Stimulation. 2019; 12.

Reisinger, DL; Shaffer, RC; Pedapati, EV; Dominick, KC; Erickson, CA. A Pilot Quantitative Evaluation of Early Life Language Development in Fragile X Syndrome. Brain Sciences. 2019; 9.

Gilbert, DL; Mink, JW; Singer, HS. Reply. Journal of Pediatrics. 2019; 204:326-327.

Gilbert, DL; Mink, JW; Singer, HS. Reply. Journal of Pediatrics. 2019; 204:324-325.

Gilbert, DL. Transcranial magnetic stimulation in attention deficit hyperactivity disorder. Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders. 2019.

Gilbert, DL. Chapter 6 Transcranial Magnetic Stimulation in Attention Deficit Hyperactivity Disorder. Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders. 2019.

Wink, LK; Pedapati, EV; Adams, R; Erickson, CA; Pedersen, KA; Morrow, EM; Kaplan, D; Siegel, M; Res, AD D I. Characterization of Medication Use in a Multicenter Sample of Pediatric Inpatients with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders. 2018; 48:3711-3719.

Williams, DL; Mazefsky, CA; Siegel, M; Erickson, C; Gabriels, RL; Kaplan, D; Mazefsky, C; Morrow, EM; Righi, G; Santangelo, SL; et al. Problem Behaviors in Autism Spectrum Disorder: Association with Verbal Ability and Adapting/Coping Skills. Journal of Autism and Developmental Disorders. 2018; 48:3668-3677.

Brenner, J; Pan, Z; Gabriels, R; Siegel, M; Erickson, C; Kaplan, D; Mazefsky, C; Morrow, EM; Righi, G; Santangelo, SL; et al. Behavioral Symptoms of Reported Abuse in Children and Adolescents with Autism Spectrum Disorder in Inpatient Settings. Journal of Autism and Developmental Disorders. 2018; 48:3727-3735.

Righi, G; Benevides, J; Sheinkopf, SJ; Siegel, M; Erickson, C; Gabriels, RL; Kaplan, D; Mazefsky, C; Morrow, EM; Santangelo, SL; et al. Predictors of Inpatient Psychiatric Hospitalization for Children and Adolescents with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders. 2018; 48:3647-3657.

Horowitz, LM; Thurm, A; Farmer, C; Mazefsky, C; Lanzillo, E; Bridge, JA; Greenbaum, R; Pao, M; Siegel, M; Erickson, C; et al. Talking About Death or Suicide: Prevalence and Clinical Correlates in Youth with Autism Spectrum Disorder in the Psychiatric Inpatient Setting. Journal of Autism and Developmental Disorders. 2018; 48:3702-3710.

Goel, A; Cantu, DA; Guilfoyle, J; Chaudhari, GR; Newadkar, A; Todisco, B; de Alba, D; Kourdougli, N; Schmitt, LM; Pedapati, E; et al. Impaired perceptual learning in a mouse model of Fragile X syndrome is mediated by parvalbumin neuron dysfunction and is reversible. Nature Neuroscience. 2018; 21:1404-1411.

Wang, S; Mandell, JD; Kumar, Y; Sun, N; Morris, MT; Arbelaez, J; Nasello, C; Dong, S; Duhn, C; Zhao, X; et al. De Novo Sequence and Copy Number Variants Are Strongly Associated with Tourette Disorder and Implicate Cell Polarity in Pathogenesis. Cell Reports. 2018; 24:3441-3454.e12.

Scher, MS; Breningstall, G; Gilbert, D; Jordan, L; Khakoo, Y; LePichon, J. The 2017 Pediatric Neurology Training Publication Award. Pediatric Neurology. 2018; 86.

Laue, C; Griffey, M; Lin, P; Wallace, K; van der Schoot, M; Horn, P; Pedapati, E; Barzman, D. Eye Gaze Patterns Associated with Aggressive Tendencies in Adolescence. Psychiatric Quarterly. 2018; 89:747-756.

Wink, LK; Adams, R; Horn, PS; Tessier, CR; Bantel, AP; Hong, M; Shaffer, RC; Pedapati, EV; Erickson, CA. A Randomized Placebo-Controlled Cross-Over Pilot Study of Riluzole for Drug-Refractory Irritability in Autism Spectrum Disorder. Journal of Autism and Developmental Disorders. 2018; 48:3051-3060.

Gilbert, DL; Espay, AJ; Wu, SW. Coxa saltans misdiagnosed as functional gait disorder: Two cases. Neurology. 2018; 91:276-277.

Gilbert, DL; Mink, JW; Singer, HS. A Pediatric Neurology Perspective on Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infection and Pediatric Acute-Onset Neuropsychiatric Syndrome. Journal of Pediatrics. 2018; 199:243-251.

Gilbert, DL; Murphy, TK; Jankovic, J; Budman, CL; Black, KJ; Kurlan, RM; Coffman, KA; McCracken, JT; Juncos, J; Grant, JE; et al. Ecopipam, a D1 receptor antagonist, for treatment of tourette syndrome in children: A randomized, placebo-controlled crossover study. Movement Disorders. 2018; 33:1272-1280.

Dominick, KC; Wink, LK; Pedapati, EV; Shaffer, R; Sweeney, JA; Erickson, CA. Risperidone Treatment for Irritability in Fragile X Syndrome. Journal of Child and Adolescent Psychopharmacology. 2018; 28:274-278.

Abdulkadir, M; Londono, D; Gordon, D; Fernandez, TV; Brown, LW; Cheon, K; Coffey, BJ; Elzerman, L; Fremer, C; Fruendt, O; et al. Investigation of previously implicated genetic variants in chronic tic disorders: a transmission disequilibrium test approach. European Archives of Psychiatry and Clinical Neuroscience. 2018; 268:301-316.

O'Malley, JA; Gilbert, DL. Clinical Approach to a Child with Movement Disorders. Seminars in Pediatric Neurology. 2018; 25:10-18.

Epperson, MV; Haws, ME; Standridge, SM; Gilbert, DL. An Atypical Rett Syndrome Phenotype Due to a Novel Missense Mutation in CACNA1A. Journal of Child Neurology. 2018; 33:286-289.

Peeters, S; Skoch, J; Holt, H; Mubita, L; Choudhary, EA; Vadivelu, KP; Gilbert, DL; Wu, SW; Keebaugh, AC; Air, E; et al. Functional Neuroanatomy of Secondary Self-Injurious Behavior. Pediatric Neurosurgery. 2018; 53:71-80.

Guthrie, MD; Gilbert, DL; Huddleston, DA; Pedapati, EV; Horn, PS; Mostofsky, SH; Wu, SW. Online Transcranial Magnetic Stimulation Protocol for Measuring Cortical Physiology Associated with Response Inhibition. Journal of Visualized Experiments. 2018.

Basu, MR; Espay, AJ; Wakefield, EG; Wu, SW. Clinical Reasoning: Importance of clinical phenomenology in the era of genetic testing. Neurology. 2018; 90:e534-e537.

Gilbert, DL; LaBare, JA; Keough, K; Feist, TB. Child Neurology Residency Program Directors and Program Coordinators 2016 Workforce Survey. Pediatric Neurology. 2018; 79:21-27.

Garris, JF; Gilbert, DL. Tics. The 5-Minute Pediatric Consult, 8th Edition. 2018.

Li, J; Qiu, L; Xu, L; Pedapati, EV; Erickson, CA; Sunar, U. (2018) Characterization of Autism Spectrum Disorder by Functional Near Infrared Spectroscopy (fNIRS).

Wink, LK; Minshawi, NF; Shaffer, RC; Plawecki, MH; Posey, DJ; Horn, PS; Adams, R; Pedapati, EV; Schaefer, TL; McDougle, CJ; et al. d-Cycloserine enhances durability of social skills training in autism spectrum disorder. Molecular Autism. 2017; 8.

Wang, J; Ethridge, LE; Mosconi, MW; White, SP; Binder, DK; Pedapati, EV; Erickson, CA; Byerly, MJ; Sweeney, JA. A resting EEG study of neocortical hyperexcitability and altered functional connectivity in fragile X syndrome. Journal of Neurodevelopmental Disorders. 2017; 9.

Erickson, CA; Davenport, MH; Schaefer, TL; Wink, LK; Pedapati, EV; Sweeney, JA; Fitzpatrick, SE; Brown, WT; Budimirovic, D; Hagerman, RJ; et al. Fragile X targeted pharmacotherapy: lessons learned and future directions. Journal of Neurodevelopmental Disorders. 2017; 9.

Ethridge, LE; White, SP; Mosconi, MW; Wang, J; Pedapati, EV; Erickson, CA; Byerly, MJ; Sweeney, JA. Neural synchronization deficits linked to cortical hyper-excitability and auditory hypersensitivity in fragile X syndrome. Molecular Autism. 2017; 8.

Muhle, RA; Reed, HE; Vo, LC; Mehta, S; McGuire, K; Veenstra-VanderWeele, J; Pedapati, E. Clinical Diagnostic Genetic Testing for Individuals With Developmental Disorders. Journal of the American Academy of Child and Adolescent Psychiatry. 2017; 56:910-913.

Scher, MS; Breningstall, G; Gilbert, DL; Jordan, L; Khakoo, Y; LePichon, J. Editorial: The 2016 Pediatric Neurology Trainee Publication Award. Pediatric Neurology. 2017; 75.

Hong, MP; Guilfoyle, JL; Mooney, LN; Wink, LK; Pedapati, EV; Shaffer, RC; Sweeney, JA; Erickson, CA. Eye gaze and pupillary response in Angelman syndrome. Research in Developmental Disabilities. 2017; 68:88-94.

McClellan, L; Dominick, KC; Pedapati, EV; Wink, LK; Erickson, CA. Lurasidone for the treatment of irritability and anger in autism spectrum disorders. Expert Opinion on Investigational Drugs. 2017; 26:985-989.

Harkins, CM; Dominick, KC; Wink, LK; Pedapati, EV; Shaffer, RC; Fitzpatrick, SE; Davenport, MH; Sweeney, JA; Erickson, CA. Challenges in Conducting Clinical Trials for Pharmacotherapies in Fragile X Syndrome: Lessons Learned. Pharmaceutical Medicine. 2017; 31:235-244.

Barfell, KS F; Snyder, RR; Isaacs-Cloes, KM; Garris, JF; Roeckner, AR; Horn, PS; Guthrie, MD; Wu, SW; Gilbert, DL. Parent and Patient Perceptions of Functional Impairment Due to Tourette Syndrome: Development of a Shortened Version of the Child Tourette Syndrome Impairment Scale. Journal of Child Neurology. 2017; 32:725-730.

Wink, LK; Adams, R; Pedapati, EV; Dominick, KC; Fox, E; Buck, C; Erickson, CA. Brief Report: Metformin for Antipsychotic-Induced Weight Gain in Youth with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders. 2017; 47:2290-2294.

Albert, DV F; Gilbert, DL. Child Neurology Training for Pediatricians. Pediatric Neurology. 2017; 71:4-7.

Gilbert, DL. Drug-Induced Movement Disorders in Children. Swaiman's Pediatric Neurology: Principles and Practice: Sixth Edition. 2017.

Augustine, EF; Gilbert, DL. Clinical pearls and scientific advancement: Reconciling tradition with new knowledge. Neurology. 2017; 88:1786-1787.

Willsey, AJ; Fernandez, TV; Yu, D; King, RA; Dietrich, A; Xing, J; Sanders, SJ; Mandell, JD; Huang, AY; Richer, P; et al. De Novo Coding Variants Are Strongly Associated with Tourette Disorder. Neuron. 2017; 94:486-499.e9.

Arya, R; Spaeth, C; Gilbert, DL; Leach, JL; Holland, KD. GNAO1-associated epileptic encephalopathy and movement disorders: c.607G>A variant represents a probable mutation hotspot with a distinct phenotype. Epileptic Disorders. 2017; 19:67-75.

Cloes, KI; Barfell, KS F; Horn, PS; Wu, SW; Jacobson, SE; Hart, KJ; Gilbert, DL. Preliminary evaluation of child self-rating using the Child Tourette Syndrome Impairment Scale. Developmental Medicine and Child Neurology. 2017; 59:284-290.

Feist, TB; Campbell, JL; LaBare, JA; Gilbert, DL. Challenges in Implementation of the New Accreditation System. Journal of Child Neurology. 2017; 32:397-402.

Wink, LK; Pedapati, EV; Horn, PS; McDougle, CJ; Erickson, CA. Multiple Antipsychotic Medication Use in Autism Spectrum Disorder. Journal of Child and Adolescent Psychopharmacology. 2017; 27:91-94.

Shaffer, RC; Pedapati, EV; Shic, F; Gaietto, K; Bowers, K; Wink, LK; Erickson, CA. Brief Report: Diminished Gaze Preference for Dynamic Social Interaction Scenes in Youth with Autism Spectrum Disorders. Journal of Autism and Developmental Disorders. 2017; 47:506-513.

Gilbert, DL; Horn, PS; Kang, PB; Mintz, M; Joshi, SM; Jr, RH; Bale, JF. Child Neurology Recruitment and Training: Views of Residents and Child Neurologists From the 2015 AAP/CNS Workforce Survey. Pediatric Neurology. 2017; 66:89-95.

Erickson, CA; Ray, B; Wink, LK; Bayon, BL; Pedapati, EV; Shaffer, R; Schaefer, TL; Lahiri, DK. Initial analysis of peripheral lymphocytic extracellular signal related kinase activation in autism. Journal of Psychiatric Research. 2017; 84:153-160.