Gilbert / Wu / Pedapati Lab Research

Goel, A; Cantu, DA; Guilfoyle, J; Chaudhari, GR; Newadkar, A; Todisco, B; de Alba, D; Kourdougli, N; Schmitt, LM; Pedapati, E; et al. Impaired perceptual learning in a mouse model of Fragile X syndrome is mediated by parvalbumin neuron dysfunction and is reversible. Nature Neuroscience. 2018; 21:1404-1411.

Larsh, TR; Wu, SW; Gilbert, DL. Comparison of Impairment in Functional Tic Disorders Versus Tourette Syndrome. Pediatric Neurology. 2022; 134:83-84.

Marshall, CS; Deng, S; Jackson, HS; Horn, PS; Wolf, DS; Thompson-Stone, R; Gilbert, DL. Adult Neurology Rotations for Child Neurology Residents: A Survey of Program Directors. Neurology. 2022.

Deng, S; Marshall, CS; Gilbert, DL; Jackson, HS; Wolf, DS; Thompson-Stone, R. Adult Neurology Rotations for Child Neurology Residents: Exploring the Resident Perspective. Pediatric Neurology. 2022; 133:34-39.

He, JL; Hirst, RJ; Puri, R; Coxon, J; Byblow, W; Hinder, M; Skippen, P; Matzke, D; Heathcote, A; Wadsley, CG; et al. OSARI, an Open-Source Anticipated Response Inhibition Task. Behavior Research Methods, Instruments, and Computers. 2022; 54:1530-1540.

Zea Vera, A; Bruce, A; Garris, J; Tochen, L; Bhatia, P; Lehman, RK; Lopez, W; Wu, SW; Gilbert, DL. The Phenomenology of Tics and Tic-Like Behavior in TikTok. Pediatric Neurology. 2022; 130:14-20.

He, JL; Mikkelsen, M; Huddleston, DA; Crocetti, D; Cecil, KM; Singer, HS; Edden, RA E; Gilbert, DL; Mostofsky, SH; Puts, NA J. Frequency and Intensity of Premonitory Urges-to-Tic in Tourette Syndrome Is Associated With Supplementary Motor Area GABA+ Levels. Movement Disorders. 2022; 37:563-573.

Neilson, DE; Zech, M; Hufnagel, RB; Slone, J; Wang, X; Homan, S; Gutzwiller, LM; Leslie, EJ; Leslie, ND; Xiao, J; et al. A Novel Variant of ATP5MC3 Associated with Both Dystonia and Spastic Paraplegia. Movement Disorders. 2022; 37:375-383.

Vera, AZ; Pedapati, EV; Larsh, TR; Kohmescher, K; Miyakoshi, M; Huddleston, DA; Jackson, HS; Gilbert, DL; Horn, PS; Wu, SW. EEG Correlates of Active Stopping and Preparation for Stopping in Chronic Tic Disorder. Brain Sciences. 2022; 12.

Pringsheim, T; Ganos, C; McGuire, JF; Hedderly, T; Woods, D; Gilbert, DL; Piacentini, J; Dale, RC; Martino, D. Rapid Onset Functional Tic-Like Behaviors in Young Females During the COVID-19 Pandemic. Movement Disorders. 2021; 36:2707-2713.

Ewen, JB; Puts, NA; Mostofsky, SH; Horn, PS; Gilbert, DL. Associations between Task-Related Modulation of Motor-Evoked Potentials and EEG Event-Related Desynchronization in Children with ADHD. Cerebral Cortex. 2021; 31:5526-5535.

Halvorsen, M; Szatkiewicz, J; Mudgal, P; Yu, D; Aschauer, H; Atzmon, G; Barr, C; Barta, C; Barzilai, N; Batterson, J; et al. Elevated common variant genetic risk for tourette syndrome in a densely-affected pedigree. Molecular Psychiatry. 2021; 26:7522-7529.

Yurkovic, JR; Lisandrelli, G; Shaffer, RC; Dominick, KC; Pedapati, EV; Erickson, CA; Kennedy, DP; Yu, C. Using head-mounted eye tracking to examine visual and manual exploration during naturalistic toy play in children with and without autism spectrum disorder. Scientific Reports. 2021; 11.

Cao, X; Zhang, Y; Abdulkadir, M; Deng, L; Fernandez, TV; Garcia-Delgar, B; Hagstrøm, J; Hoekstra, PJ; King, RA; Koesterich, J; et al. Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families. Molecular Psychiatry. 2021; 26:6937-6951.

Abdulkadir, M; Yu, D; Osiecki, L; King, RA; Fernandez, TV; Brown, LW; Cheon, KA; Coffey, BJ; Garcia-Delgar, B; Gilbert, DL; et al. Investigation of gene-environment interactions in relation to tic severity. Journal of Neural Transmission. 2021; 128:1757-1765.

Ganos, C; Sarva, H; Kurvits, L; Gilbert, DL; Hartmann, A; Worbe, Y; Mir, P; Müller-Vahl, KR; Münchau, A; Shprecher, D; et al. Clinical Practice Patterns in Tic Disorders Among Movement Disorder Society Members. Tremor and Other Hyperkinetic Movements. 2021; 11.

Larsh, T; Wu, SW; Vadivelu, S; Grant, GA; O'Malley, JA. Deep Brain Stimulation for Pediatric Dystonia. Seminars in Pediatric Neurology. 2021; 38.

Tsetsos, F; Yu, D; Sul, JH; Huang, AY; Illmann, C; Osiecki, L; Darrow, SM; Hirschtritt, ME; Greenberg, E; Muller-Vahl, KR; et al. Synaptic processes and immune-related pathways implicated in Tourette syndrome. Translational Psychiatry. 2021; 11.

Smith, EG; Pedapati, EV; Liu, R; Schmitt, LM; Dominick, KC; Shaffer, RC; Sweeney, JA; Erickson, CA. Sex differences in resting EEG power in Fragile X Syndrome. Journal of Psychiatric Research. 2021; 138:89-95.

Harris, AD; Gilbert, DL; Horn, PS; Crocetti, D; Cecil, KM; Edden, RA E; Huddleston, DA; Mostofsky, SH; Puts, NA J. Relationship between GABA levels and task-dependent cortical excitability in children with attention-deficit/hyperactivity disorder. Electromyography and Clinical Neurophysiology. 2021; 132:1163-1172.

Detrick, JA; Zink, C; Rosch, KS; Horn, PS; Huddleston, DA; Crocetti, D; Wu, SW; Pedapati, EV; Wassermann, EM; Mostofsky, SH; et al. Motor cortex modulation and reward in children with attention-deficit/hyperactivity disorder. Brain Communications. 2021; 3.

Wink, LK; Reisinger, DL; Horn, P; Shaffer, RC; O'Brien, K; Schmitt, L; Dominick, KR; Pedapati, EV; Erickson, CA. Brief Report: Intranasal Ketamine in Adolescents and Young Adults with Autism Spectrum Disorder-Initial Results of a Randomized, Controlled, Crossover, Pilot Study. Journal of Autism and Developmental Disorders. 2021; 51:1392-1399.

Garris, JF; Huddleston, DA; Jackson, HS; Horn, PS; Gilbert, DL. Implementation of the Mini-Child Tourette Syndrome Impairment Scale: Relationships to Symptom Severity and Treatment Decisions. Journal of Child Neurology. 2021; 36:288-295.

Bruce, AB; Yuan, W; Gilbert, DL; Horn, PS; Jackson, HS; Huddleston, DA; Wu, SW. Altered frontal-mediated inhibition and white matter connectivity in pediatric chronic tic disorders. Experimental Brain Research. 2021; 239:955-965.

Zea Vera, A; Liu, W; Thomas, C; Gilbert, DL. Pearls & Oy-sters: A Novel Presentation of Ataxia With Vitamin E Deficiency Caused by TTPA Gene Mutation. Neurology. 2021; 96:e640-e642.

Miyakoshi, M; Schmitt, LM; Erickson, CA; Sweeney, JA; Pedapati, EV. Can We Push the "Quasi-Perfect Artifact Rejection " Even Closer to Perfection?. Frontiers in Neuroinformatics. 2021; 14.

Rossi, S; Antal, A; Bestmann, S; Bikson, M; Brewer, C; Brockmöller, J; Carpenter, LL; Cincotta, M; Chen, R; Daskalakis, JD; et al. Safety and recommendations for TMS use in healthy subjects and patient populations, with updates on training, ethical and regulatory issues: Expert Guidelines. Electromyography and Clinical Neurophysiology. 2021; 132:269-306.

Lamy, M; Pedapati, EV; Dominick, KL; Wink, LK; Erickson, CA. Recent Advances in the Pharmacological Management of Behavioral Disturbances Associated with Autism Spectrum Disorder in Children and Adolescents. Paediatric Drugs. 2020; 22:473-483.

Shillington, A; Pedapati, E; Hopkin, R; Suhrie, K. Early behavioral and developmental interventions in ADNP-syndrome: A case report of SWI/SNF-related neurodevelopmental syndrome. Molecular genetics & genomic medicine. 2020; 8.

Coffman, MC; Shaffer, RC; Schmitt, LM; Dominick, KC; Pedapati, E; Wang, A; Berry-Kravis, E; Tartaglia, N; Erickson, CA. Examination of Correlates to Health-Related Quality of Life in Individuals with Fragile X Syndrome. Brain Sciences. 2020; 10.

Fitzpatrick, SE; Schmitt, LM; Adams, R; Pedapati, EV; Wink, LK; Shaffer, RC; Sage, J; Weber, JD; Dominick, KC; Erickson, CA. Pediatric Quality of Life Inventory (PedsQL) in Fragile X Syndrome. Journal of Autism and Developmental Disorders. 2020; 50:1056-1063.

Reisinger, DL; Shaffer, RC; Horn, PS; Hong, MP; Pedapati, EV; Dominick, KC; Erickson, CA. Atypical Social Attention and Emotional Face Processing in Autism Spectrum Disorder: Insights From Face Scanning and Pupillometry. Frontiers in Integrative Neuroscience. 2020; 13.

Shaffer, RC; Schmitt, L; Thurman, AJ; Abbeduto, L; Hong, M; Pedapati, E; Dominick, K; Sweeney, J; Erickson, C. The Relationship between Expressive Language Sampling and Clinical Measures in Fragile X Syndrome and Typical Development. Brain Sciences. 2020; 10.

Schmitt, LM; Wang, J; Pedapati, EV; Thurman, AJ; Abbeduto, L; Erickson, CA; Sweeney, JA. A neurophysiological model of speech production deficits in fragile X syndrome. Brain Communications. 2020; 2.

Lee, PH; Anttila, V; Won, H; Feng, YA; Rosenthal, J; Zhu, Z; Tucker-Drob, EM; Nivard, MG; Grotzinger, AD; Posthuma, D; et al. Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders. Cell. 2019; 179:1469-1482.e11.

Pedapati, EV; Mooney, LN; Wu, SW; Erickson, CA; Sweeney, JA; Shaffer, RC; Horn, PS; Wink, LK; Gilbert, DL. Motor cortex facilitation: a marker of attention deficit hyperactivity disorder co-occurrence in autism spectrum disorder. Translational Psychiatry. 2019; 9.

Scher, MS; Breningstall, G; Gilbert, D; Jordan, L; Khakoo, Y; LePichon, J. The 2018 Pediatric Neurology Trainee Publication Award. Pediatric Neurology. 2019; 101.

Feist, TB; Gilbert, DL. Program Administrator Burnout: More Than a Wellness Issue. Journal of graduate medical education. 2019; 11.

Mufford, M; Cheung, J; Jahanshad, N; van der Merwe, C; Ding, L; Groenewold, N; Koen, N; Chimusa, ER; Dalvie, S; Ramesar, R; et al. Concordance of genetic variation that increases risk for tourette syndrome and that influences its underlying neurocircuitry. Translational Psychiatry. 2019; 9.

Hong, MP; Eckert, EM; Pedapati, EV; Shaffer, RC; Dominick, KC; Wink, LK; Sweeney, JA; Erickson, CA. Differentiating social preference and social anxiety phenotypes in fragile X syndrome using an eye gaze analysis: a pilot study. Journal of Neurodevelopmental Disorders. 2019; 11.

Eckert, EM; Dominick, KC; Pedapati, EV; Wink, LK; Shaffer, RC; Andrews, H; Choo, T; Chen, C; Kaufmann, WE; Tartaglia, N; et al. Pharmacologic Interventions for Irritability, Aggression, Agitation and Self-Injurious Behavior in Fragile X Syndrome: An Initial Cross-Sectional Analysis. Journal of Autism and Developmental Disorders. 2019; 49:4595-4602.

Ethridge, LE; De Stefano, LA; Schmitt, LM; Woodruff, NE; Brown, KL; Tran, M; Wang, J; Pedapati, EV; Erickson, CA; Sweeney, JA. Auditory EEG Biomarkers in Fragile X Syndrome: Clinical Relevance. Frontiers in Integrative Neuroscience. 2019; 13.

McLane, RD; Schmitt, LM; Pedapati, EV; Shaffer, RC; Dominick, KC; Horn, PS; Gross, C; Erickson, CA. Peripheral Amyloid Precursor Protein Derivative Expression in Fragile X Syndrome. Frontiers in Integrative Neuroscience. 2019; 13.

Gilbert, DL. Inflammation in Tic Disorders and Obsessive-Compulsive Disorder: Are PANS and PANDAS a Path Forward?. Journal of Child Neurology. 2019; 34:598-611.

Gilbert, DL; Huddleston, DA; Wu, SW; Pedapati, EV; Horn, PS; Hirabayashi, K; Crocetti, D; Wassermann, EM; Mostofsky, SH. Motor cortex inhibition and modulation in children with ADHD. Neurology. 2019; 93:e599-e610.

Gilbert, DL. Treatment of Tourette Syndrome: Medical Therapy. Therapy of Movement Disorders. 2019.

Yu, D; Sul, JH; Tsetsos, F; Nawaz, MS; Huang, AY; Zelaya, I; Illmann, C; Osiecki, L; Darrow, SM; Hirschtritt, ME; et al. Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies. American Journal of Psychiatry. 2019; 176:217-227.

Wu, S; Pedapati, E; Roeckner, A; Huddleston, D; Jackson, H; Gilbert, D. Decreased functional connectivity between frontal and motor cortex in Tourette Syndrome. Brain Stimulation. 2019; 12.

Gilbert, D; Wu, S; Horn, P; Pedapati, E; Mostofsky, S. Reduced motor cortex modulation during response inhibition task correlates with worse performance more severe clinical and motor impairment in children with ADHD. Brain Stimulation. 2019; 12.

Pedapati, E; Mooney, L; Wu, S; Sweeney, J; Erickson, C; Gilbert, D. Motor Cortex Facilitation: An inattention marker in ADHD co-occurrence in Autism Spectrum Disorder. Brain Stimulation. 2019; 12.

Reisinger, DL; Shaffer, RC; Pedapati, EV; Dominick, KC; Erickson, CA. A Pilot Quantitative Evaluation of Early Life Language Development in Fragile X Syndrome. Brain Sciences. 2019; 9.

Gilbert, DL; Mink, JW; Singer, HS. Reply. Journal of Pediatrics. 2019; 204:326-327.

Gilbert, DL; Mink, JW; Singer, HS. Reply. Journal of Pediatrics. 2019; 204:324-325.

Gilbert, DL. Transcranial magnetic stimulation in attention deficit hyperactivity disorder. Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders. 2019.

Gilbert, DL. Chapter 6 Transcranial Magnetic Stimulation in Attention Deficit Hyperactivity Disorder. Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders. 2019.

Wink, LK; Pedapati, EV; Adams, R; Erickson, CA; Pedersen, KA; Morrow, EM; Kaplan, D; Siegel, M; Res, AD D I. Characterization of Medication Use in a Multicenter Sample of Pediatric Inpatients with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders. 2018; 48:3711-3719.

Williams, DL; Siegel, M; Mazefsky, CA; Erickson, C; Gabriels, RL; Kaplan, D; Mazefsky, C; Morrow, EM; Righi, G; Santangelo, SL; et al. Problem Behaviors in Autism Spectrum Disorder: Association with Verbal Ability and Adapting/Coping Skills. Journal of Autism and Developmental Disorders. 2018; 48:3668-3677.

Brenner, J; Pan, Z; Smith, KA; Gabriels, R; Siegel, M; Erickson, C; Kaplan, D; Mazefsky, C; Morrow, EM; Righi, G; et al. Behavioral Symptoms of Reported Abuse in Children and Adolescents with Autism Spectrum Disorder in Inpatient Settings. Journal of Autism and Developmental Disorders. 2018; 48:3727-3735.

Righi, G; Benevides, J; Siegel, M; Sheinkopf, SJ; Morrow, EM; Erickson, C; Gabriels, RL; Kaplan, D; Mazefsky, C; Santangelo, SL; et al. Predictors of Inpatient Psychiatric Hospitalization for Children and Adolescents with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders. 2018; 48:3647-3657.

Horowitz, LM; Thurm, A; Farmer, C; Mazefsky, C; Lanzillo, E; Bridge, JA; Greenbaum, R; Pao, M; Siegel, M; Erickson, C; et al. Talking About Death or Suicide: Prevalence and Clinical Correlates in Youth with Autism Spectrum Disorder in the Psychiatric Inpatient Setting. Journal of Autism and Developmental Disorders. 2018; 48:3702-3710.

Goel, A; Cantu, DA; Guilfoyle, J; Chaudhari, GR; Newadkar, A; Todisco, B; de Alba, D; Kourdougli, N; Schmitt, LM; Pedapati, E; et al. Impaired perceptual learning in a mouse model of Fragile X syndrome is mediated by parvalbumin neuron dysfunction and is reversible. Nature Neuroscience. 2018; 21:1404-1411.

Wang, S; Mandell, JD; Kumar, Y; Sun, N; Morris, MT; Arbelaez, J; Nasello, C; Dong, S; Duhn, C; Zhao, X; et al. De Novo Sequence and Copy Number Variants Are Strongly Associated with Tourette Disorder and Implicate Cell Polarity in Pathogenesis. Cell Reports. 2018; 24:3441-3454.e12.

Scher, MS; Breningstall, G; Gilbert, D; Jordan, L; Khakoo, Y; LePichon, J. The 2017 Pediatric Neurology Training Publication Award. Pediatric Neurology. 2018; 86.

Laue, C; Griffey, M; Lin, P; Wallace, K; van der Schoot, M; Horn, P; Pedapati, E; Barzman, D. Eye Gaze Patterns Associated with Aggressive Tendencies in Adolescence. Psychiatric Quarterly. 2018; 89:747-756.

Wink, LK; Adams, R; Horn, PS; Tessier, CR; Bantel, AP; Hong, M; Shaffer, RC; Pedapati, EV; Erickson, CA. A Randomized Placebo-Controlled Cross-Over Pilot Study of Riluzole for Drug-Refractory Irritability in Autism Spectrum Disorder. Journal of Autism and Developmental Disorders. 2018; 48:3051-3060.

Gilbert, DL; Espay, AJ; Wu, SW. Coxa saltans misdiagnosed as functional gait disorder: Two cases. Neurology. 2018; 91:276-277.

Gilbert, DL; Mink, JW; Singer, HS. A Pediatric Neurology Perspective on Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infection and Pediatric Acute-Onset Neuropsychiatric Syndrome. Journal of Pediatrics. 2018; 199:243-251.

Gilbert, DL; Murphy, TK; Jankovic, J; Budman, CL; Black, KJ; Kurlan, RM; Coffman, KA; McCracken, JT; Juncos, J; Grant, JE; et al. Ecopipam, a D1 receptor antagonist, for treatment of tourette syndrome in children: A randomized, placebo-controlled crossover study. Movement Disorders. 2018; 33:1272-1280.

Dominick, KC; Wink, LK; Pedapati, EV; Shaffer, R; Sweeney, JA; Erickson, CA. Risperidone Treatment for Irritability in Fragile X Syndrome. Journal of Child and Adolescent Psychopharmacology. 2018; 28:274-278.

Abdulkadir, M; Londono, D; Gordon, D; Fernandez, TV; Brown, LW; Cheon, K; Coffey, BJ; Elzerman, L; Fremer, C; Fruendt, O; et al. Investigation of previously implicated genetic variants in chronic tic disorders: a transmission disequilibrium test approach. European Archives of Psychiatry and Clinical Neuroscience. 2018; 268:301-316.

O'Malley, JA; Gilbert, DL. Clinical Approach to a Child with Movement Disorders. Seminars in Pediatric Neurology. 2018; 25:10-18.

Epperson, MV; Haws, ME; Standridge, SM; Gilbert, DL. An Atypical Rett Syndrome Phenotype Due to a Novel Missense Mutation in CACNA1A. Journal of Child Neurology. 2018; 33:286-289.

Peeters, S; Skoch, J; Holt, H; Mubita, L; Choudhary, EA; Vadivelu, KP; Gilbert, DL; Wu, SW; Keebaugh, AC; Air, E; et al. Functional Neuroanatomy of Secondary Self-Injurious Behavior. Pediatric Neurosurgery. 2018; 53:71-80.

Guthrie, MD; Gilbert, DL; Huddleston, DA; Pedapati, EV; Horn, PS; Mostofsky, SH; Wu, SW. Online Transcranial Magnetic Stimulation Protocol for Measuring Cortical Physiology Associated with Response Inhibition. Journal of Visualized Experiments. 2018.

Basu, MR; Espay, AJ; Wakefield, EG; Wu, SW. Clinical Reasoning: Importance of clinical phenomenology in the era of genetic testing. Neurology. 2018; 90:e534-e537.

Gilbert, DL; LaBare, JA; Keough, K; Feist, TB. Child Neurology Residency Program Directors and Program Coordinators 2016 Workforce Survey. Pediatric Neurology. 2018; 79:21-27.

Garris, JF; Gilbert, DL. Tics. The 5-Minute Pediatric Consult, 8th Edition. 2018.

Li, J; Qiu, L; Xu, L; Pedapati, EV; Erickson, CA; Sunar, U. (2018) Characterization of Autism Spectrum Disorder by Functional Near Infrared Spectroscopy (fNIRS).