Gilbert / Wu / Pedapati Lab Research

Publications

Goel, A; Cantu, DA; Guilfoyle, J; Chaudhari, GR; Newadkar, A; Todisco, B; de Alba, D; Kourdougli, N; Schmitt, LM; Pedapati, E; Erickson, CA; Portera-Cailliau, C. Impaired perceptual learning in a mouse model of Fragile X syndrome is mediated by parvalbumin neuron dysfunction and is reversible. Nature Neuroscience. 2018; 21:1404-1411.

Elmaghraby, R; Liu, Y; Ramesh, P; Westerkamp, G; Nelson, MA; Larsh, T; Smith, E; Gilbert, DL; Wu, SW; Erickson, CA; Pedapati, EV. Divergent aperiodic slope and alpha dynamics expose cortical excitability gradients in fragile X syndrome. Molecular Autism. 2025; 16:49.

McGuire, JF; Karkanias, GB; Bittman, RM; Atkinson, SD; Munschauer, FE; Wanaski, SP; Cunniff, TM; Gilbert, DL. Determining Clinically Meaningful Improvement in Children and Adolescents with Tourette Syndrome Receiving Pharmacotherapy. Journal of Child and Adolescent Psychopharmacology. 2025; 35:447-453.

Marsili, L; Kauffman, MA; Talavera de la Esperanza, B; Yu, Z; Gilbert, DL; Espay, AJ. "Mini Molar Tooth " Sign in POLR3B-Associated Cerebellar Ataxia with Hypomyelinating Leukodystrophy. Movement Disorders Clinical Practice. 2025; 12:1659-1661.

Gilbert, DL; Atkinson, SD; Kim, DJ B; Miller, MM; Rice, PM; Flatt, JA; Cubic, A; Karkanias, GB; Munschauer, FE; Wanaski, SP; Cunniff, TM; Tomczak, KK. 6.74 Efficacy of Ecopipam on Motor and Phonic Tics in Tourette’s Disorder: Data From a Phase 3 Randomized, Double-Blind, Placebo-Controlled Trial. Journal of the American Academy of Child and Adolescent Psychiatry. 2025; 64:s328.

Gemperli, K; Lu, X; Chintalapati, K; Rust, A; Bajpai, R; Suh, N; Blackburn, J; Gelineau-Morel, R; Kruer, MC; Mingbunjerdsuk, D; Perlmutter, J; Mennerick, S; McCall, JG; Aravamuthan, BR. Chronic Striatal Cholinergic Interneuron Excitation Causes Cerebral Palsy-Related Dystonic Behavior in Mice. Annals of Neurology. 2025; 98:726-740.

Rogers, D; Stone, RT; Ream, M; Pearson, R; Pagano, LM; Bernson‐Leung, ME; Troy, E; Otallah, SI; Kossoff, EH; Kessler, SK; Schreiner, TL; Wallace, A; Foster‐Barber, A; Gottlieb‐Smith, R. Essential Components of Child Neurology Training: Program Director Consensus Recommendations. 2025.

Citarella, J; Siekierski, P; Ethridge, L; Westerkamp, G; Liu, Y; Blank, E; Voorhees, L; Batterink, L; Jones, SR; Smith, E; Horn, PS; De Stefano, LA; Erickson, CA; Pedapati, EV. FX ENTRAIN: scientific context, study design, and biomarker driven brain-computer interfaces in neurodevelopmental conditions. Frontiers in Neuroscience. 2025; 19:1618804.

Erickson, CA; Shaffer, RC; Will, M; Schmitt, LM; Horn, P; Hirst, K; Pedapati, EV; Ober, N; Tumuluru, RV; Handen, BL; Beversdorf, DQ. Brief Report: A Double-Blind, Placebo-Controlled, Crossover, Proof-of-Concept Study of Minocycline in Autism Spectrum Disorder. Journal of Autism and Developmental Disorders. 2025; 55:3387-3394.

Gilbert, DL; Kim, DJ B; Miller, MM; Atkinson, SD; Karkanias, GB; Munschauer, FE; Wanaski, SP; Cunniff, TM. Safety and Effect of 12-Month Ecopipam Treatment in Pediatric Patients with Tourette Syndrome. Movement Disorders Clinical Practice. 2025; 12:1157-1166.

Gilbert, DL; Huddleston, DA; Migneault, KY; Crocetti, D; Horn, PS; Wu, SW; Mostofsky, SH. Reliability of short interval cortical inhibition in children with attention deficit hyperactivity disorder. Clinical Neurophysiology. 2025; 175:2110750.

Miyakoshi, M; Kim, H; De Stefano, LA; Schmitt, LM; Norris, JE; Ethridge, LE; Erickson, CA; Pedapati, EV. Hyper-extralemniscal model of Fragile X syndrome. Cerebral Cortex. 2025; 35:bhaf141.

Argonis, RA; Pedapati, EV; Dominick, KC; Harris, K; Lamy, M; Fosdick, C; Schmitt, L; Shaffer, RC; Smith, E; Will, M; McDougle, CJ; Erickson, CA. Patterns in Medication Use for Treatment of Depression in Autistic Spectrum Disorder. Journal of Autism and Developmental Disorders. 2025; 55:1969-1975.

Pedapati, EV; Ethridge, LE; Liu, Y; Liu, R; Sweeney, JA; DeStefano, LA; Miyakoshi, M; Razak, K; Schmitt, LM; Moore, DR; Dominick, KC; Horn, PS; Binder, D; Erickson, CA. Frontal cortex hyperactivation and gamma desynchrony in Fragile X syndrome: Correlates of auditory hypersensitivity. Editor, Narmashiri A. PloS one. 2025; 20:e0306157.

Elmaghraby, R; Blank, E; Miyakoshi, M; Gilbert, DL; Wu, SW; Larsh, T; Westerkamp, G; Liu, Y; Horn, PS; Erickson, CA; Pedapati, EV. Probing the Neurodynamic Mechanisms of Cognitive Flexibility in Depressed Individuals with Autism Spectrum Disorder. Journal of Child and Adolescent Psychopharmacology. 2025; 35:231-243.

McKinney, WS; Schmitt, LM; De Stefano, LA; Ethridge, L; Norris, JE; Horn, PS; Dauterman, S; Rosselot, H; Pedapati, EV; Reisinger, DL; Friedman, NR; Hong, M; Sweeney, JA; Erickson, C. Results from a Double-Blind, Randomized, Placebo-Controlled, Single-Dose, Crossover Trial of Lovastatin or Minocycline in Fragile X Syndrome. Journal of Child and Adolescent Psychopharmacology. 2025; 35:211-221.

McGuire, JF; Karkanias, GB; Bittman, RB; Atkinson, SD; Messner, GD; Munschauer, FE; Wanaski, SP; Cunniff, TM; Gilbert, DL. Changes in Metabolic Parameters and Determination of Minimal Clinically Important Difference in YGTSS-TTS Using Data From the Randomized Phase 2b and Open-Label Extension Studies of Ecopipam For Tourette Syndrome (P11-6.002). Neurology. 2025; 104.

Strom, NI; Halvorsen, MW; Grove, J; Ásbjörnsdóttir, B; Luðvígsson, P; Thorarensen, Ó; de Schipper, E; Bäckmann, J; Andrén, P; Tian, C; Elson, SL; Fontanillas, P; Furlotte, NA; Hicks, B. Genome-Wide Association Study Meta-Analysis of 9619 Cases With Tic Disorders. Biological Psychiatry. 2025; 97:743-752.

Schierbaum, L; Quiroz, V; Yang, K; Rong, J; Battaglia, N; Zubair, U; Christie, M; Davis, M; Calame, D; Danzi, MC; Fink, JK; Shy, ME; Zuchner, S; Ebrahimi-Fakhari, D. The Spastic Paraplegia-Centers of Excellence Research Network (SP-CERN): Clinical Trial Readiness for Hereditary Spastic Paraplegia. Neurology: Genetics. 2025; 11:e200249.

Gilbert, DL; Crocetti, D; Horn, PS; Wu, SW; Huddleston, DA; Ehrman, JM; Migneault, KY; Mostofsky, SH. In children with attention‐deficit/hyperactivity disorder, less task‐related up‐modulation of motor cortex during response inhibition. 2025; 3:26-36.

Blank, E; Gilbert, DL; Wu, SW; Larsh, T; Elmaghraby, R; Liu, R; Smith, E; Westerkamp, G; Liu, Y; Horn, PS; Greenstein, E; Sweeney, JA; Erickson, CA; Pedapati, EV. Accelerated Theta Burst Transcranial Magnetic Stimulation for Refractory Depression in Autism Spectrum Disorder. Journal of Autism and Developmental Disorders. 2025; 55:940-954.

Koenig, MK; Leuzzi, V; Gouider, R; Yiu, EM; Pietrucha, B; Stray-Pedersen, A; Perlman, SL; Wu, S; Burgers, T; Borgohain, R; Thye, D; Horn, B; Lederman, HM; Whitehouse, WP. Long-term safety of dexamethasone sodium phosphate encapsulated in autologous erythrocytes in pediatric patients with ataxia telangiectasia. Frontiers in Neurology. 2025; 15:1526914.

Krolick, A; Hwu, P; Gilbert, D; Ben-Zeev, B; Curry, D; Stone, S; Vestal, M; Werner, C; Penematsa, V; Wang, A; Rahman, R; Golden, L; Pearl, P. O14: Administration of eladocagene exuparvovec using the SmartFlow magnetic resonance-compatible ventricular cannula in pediatric patients with aromatic ʟ-amino acid decarboxylase deficiency. Genetics in Medicine Open. 2025; 3:102090.

Larsh, T; Gilbert, D; Wu, S. Deep brain stimulation modulates pallidal and cortical aperiodic activity during a motor task in children and young adults with dystonia. Brain Stimulation. 2025; 18:520.

Elsayed, Z; Miyakoshi, M; Suer, N; Erickson, C; Westerkamp, G; Pedapati, E; Liu, JY. (2024) Computer Vision Based Neurology Brain Activity Rejection Architecture and Implementation. Institute of Electrical and Electronics Engineers (IEEE). 00:1481-1487.

Smith, E; Dominick, KC; Schmitt, LM; Pedapati, EV; Erickson, CA. Specialization of the brain for language in children with Fragile X Syndrome: a functional Near Infrared Spectroscopy study. Journal of Neurodevelopmental Disorders. 2024; 16:69.

Gottlieb-Smith, R; Rogers, D; Gilbert, DL. Modified Delphi Study to Establish Consensus About Child Neurology Residency Education: Next-Gen Training. Neurology. 2024; 103:e210002.

Sund, KL; Liu, J; Lee, J; Garbe, J; Abdelhamed, Z; Maag, C; Hallinan, B; Wu, SW; Sperry, E; Deshpande, A; Stottmann, R; Smolarek, TA; Dyer, LM; Hestand, MS. Long-read sequencing and optical genome mapping identify causative gene disruptions in noncoding sequence in two patients with neurologic disease and known chromosome abnormalities. American Journal of Medical Genetics, Part A. 2024; 194:e63818.

Ethridge, LE; Pedapati, EV; Schmitt, LM; Norris, JE; Auger, E; De Stefano, LA; Sweeney, JA; Erickson, CA. Validating brain activity measures as reliable indicators of individual diagnostic group and genetically mediated sub-group membership Fragile X Syndrome. Scientific Reports. 2024; 14:22982.

Srivastava, S; Cole, JJ; Cohen, JS; Chopra, M; Smith, HS; Deardorff, MA; Pedapati, E; Corner, B; Anixt, JS; Jeste, S; Sahin, M; Gurnett, CA; Campbell, CA. Survey of the Landscape of Society Practice Guidelines for Genetic Testing of Neurodevelopmental Disorders. Annals of Neurology. 2024; 96:900-913.

Larsh, TR; Gilbert, DL; Vadivelu, S; Binder, DK; Pedapati, EV; Wu, SW. Post Deep Brain Stimulation Time Course of Aperiodic Activity in Childhood and Young Adult Dystonia. Movement Disorders Clinical Practice. 2024; 11:1305-1307.

McGuire, JF; Karkanias, GB; Bittman, RM; Atkinson, SD; Munschauer, FE; Wanaski, SP; Cunniff, TM; Gilbert, DL. 6.72 An Anchor-Based Method to Establish Clinically Meaningful Changes in YGTSS-TTS Using Data From the Pooled D1AMOND Clinical Studies of Ecopipam, a Selective D1 Receptor Antagonist, in Tourette's Disorder. Journal of the American Academy of Child and Adolescent Psychiatry. 2024; 63:s303.

Pedapati, E; Gwynette, MF. A CHILD AND ADOLESCENT PSYCHIATRISTS' NEW ASSISTANT: WORKSHOP ON HARNESSING CHAT-BASED ARTIFICIAL INTELLIGENCE FOR NON-PATIENT CARE TASKS. Journal of the American Academy of Child and Adolescent Psychiatry. 2024; 63:s379.

Fox, NA; Pérez-Edgar, K; Morales, S; Brito, NH; Campbell, AM; Cavanagh, JF; Gabard-Durnam, LJ; Hudac, CM; Key, AP; Larson-Prior, LJ; Stosur, R; Tan, E; Troller-Renfree, SV; Yoder, L. The development and structure of the HEALthy Brain and Child Development (HBCD) Study EEG protocol. Developmental Cognitive Neuroscience. 2024; 69:101447.

Pedapati, E. 88.3 Impulsivity, Inattention, and Hyperactivity and Comorbid Mood Dysregulation in Intellectual and Developmental Disorders: A Challenging Intersection. Journal of the American Academy of Child and Adolescent Psychiatry. 2024; 63:s124.

Zielen, S; Crawford, T; Benatti, L; Magnani, M; Kieslich, M; Ryan, M; Meyts, I; Gulati, S; Borgohain, R; Yadav, R; Janhofer, G; Horn, B; Whitehouse, W; Lederman, H. Safety and efficacy of intra-erythrocyte dexamethasone sodium phosphate in children with ataxia telangiectasia (ATTeST): a multicentre, randomised, double-blind, placebo-controlled phase 3 trial. Lancet Neurology. 2024; 23:871-882.

Sarchioto, M; Frey, J; Ganos, C; Gilbert, DL; Hartmann, A; Hedderly, T; Isaacs, D; Malaty, I; Martindale, JM; Medina Escobar, A; Tomczak, K; Worbe, Y; Pringsheim, T; Martino, D. Diagnostic Criteria for Primary Tic Disorders: Time for Reappraisal. Movement Disorders. 2024; 39:1276-1281.

Bhatnagar, S; Mitelpunkt, A; Rizzo, JJ; Zhang, N; Guzman, T; Schuetter, R; Vargus-Adams, J; Bailes, AF; Greve, K; Gerstle, M; Pedapati, E; Aronow, B; Kurowski, BG. Mental Health Diagnoses Risk Among Children and Young Adults With Cerebral Palsy, Chronic Conditions, or Typical Development. JAMA Network Open. 2024; 7:e2422202.

Tsetsos, F; Topaloudi, A; Jain, P; Yang, Z; Yu, D; Kolovos, P; Tumer, Z; Rizzo, R; Hartmann, A; Depienne, C; Pellico, A; Ruhrman, D; Schnell, J; Silvestri, PR. Genome-Wide Association Study Points to Novel Locus for Gilles de la Tourette Syndrome. Biological Psychiatry. 2024; 96:114-124.

Erickson, CA; Perez-Cano, L; Pedapati, EV; Painbeni, E; Bonfils, G; Schmitt, LM; Sachs, H; Nelson, M; De Stefano, L; Westerkamp, G; Issachar, G; Blaettler, T; Hyvelin, JM; Durham, LA. Safety, Tolerability, and EEG-Based Target Engagement of STP1 (PDE3,4 Inhibitor and NKCC1 Antagonist) in a Randomized Clinical Trial in a Subgroup of Patients with ASD. Biomedicines. 2024; 12:1430.

ElSayed, Z; Suer, N; Westerkamp, G; Liu, JY; Miyakoshi, M; Erickson, C; Pedapati, E. CNN Brain Label-Maker: Computer Vision Based ICA Rejection EEG based System Architecture. Editor, Chun SA; Talbert DA. 2024; 37.

Takarae, Y; Zanesco, A; Erickson, CA; Pedapati, EV. EEG Microstates as Markers for Cognitive Impairments in Fragile X Syndrome. Brain Topography: journal of functional neurophysiology. 2024; 37:432-446.

Pearl, P; Gilbert, D; Ben-Zeev, B; Curry, D; Stone, S; Vestal, M; Sierra, R; Penematsa, V; Wang, A; Golden, L; Hwu, PW-L. Pharmacodynamics of Eladocagene Exuparvovec and Safety of the SmartFlow Magnetic Resonance-compatible Ventricular Cannula for Administering Eladocagene Exuparvovec in Pediatric Participants (P10-3.005). Neurology. 2024; 102.

Gilbert, D; Cunniff, T; Munschauer, F; Karkanias, G; Atkinson, S; Wanaski, S. Safety and Tolerability of Ecopipam in Tourette Syndrome with Psychiatric Comorbidities (P10-3.001). Neurology. 2024; 102.

Gilbert, D; Karkanias, G; Munschauer, F; Wanaski, S; Cunniff, T. Effect of Ecopipam, a Selective Dopamine-1 Receptor Antagonist, on Tic Characteristics as Assessed by the YGTSS: Results from the Phase IIb (D1AMOND) Randomized, Double-blind, Placebo-controlled Clinical Trial in Tourette Syndrome (S30.009). Neurology. 2024; 102.

Dusing, MR; Lasarge, CL; Drake, AW; Westerkamp, GC; McCoy, C; Hetzer, SM; Kraus, KL; Pedapati, EV; Danzer, SC. Transient Seizure Clusters and Epileptiform Activity Following Widespread Bilateral Hippocampal Interneuron Ablation. eNeuro. 2024; 11:eneuro.0317-eneu23.2024.

Coppola, T; Hughes, H; Finch, PT; Hess, JA; Wu, S; Prada, CE; Miethke, AG; Zhang, W; Kalfa, TA. Case Report: Childhood Erythrocytosis due to Hypermanganesemia Caused by Homozygous SLC30A10 Mutation. Frontiers in Hematology. 2024; 3:1331485.

Larsh, TR; Wu, SW; Huddleston, DA; Lipps, TD; Gilbert, DL. Differences in Tic Severity Among Adolescent Girls and Boys with Tourette Syndrome During the Pandemic. Neuropediatrics: journal of pediatric neurobiology, neurology and neurosurgery. 2024; 55:67-70.

Klaiman, C; White, S; Richardson, S; McQueen, E; Walum, H; Aoki, C; Smith, C; Minjarez, M; Bernier, R; Pedapati, E; Deng, Y; Jones, W; Gillespie, S; Klin, A. Expert Clinician Certainty in Diagnosing Autism Spectrum Disorder in 16-30-Month-Olds: A Multi-site Trial Secondary Analysis. Journal of Autism and Developmental Disorders. 2024; 54:393-408.

Kahlon, S; Barton, CR; Abu Libdeh, A; O'Malley, JA; Pearson, T; Waugh, JL; Wu, SW; Zea Vera, AG; Kruer, MC. Emerging Subspecialties: Pediatric Movement Disorders Neurology. Neurology. 2024; 102:e208050.

Wang, S; Wang, B; Drury, V; Drake, S; Sun, N; Alkhairo, H; Arbelaez, J; Duhn, C; Bromberg, Y; Brown, LW; O’Donovan, MC; Thapar, A; State, MW; Willsey, AJ. Rare X-linked variants carry predominantly male risk in autism, Tourette syndrome, and ADHD. Nature Communications. 2023; 14:8077.

Jain, P; Miller-Fleming, T; Topaloudi, A; Yu, D; Drineas, P; Georgitsi, M; Yang, Z; Rizzo, R; Müller-Vahl, KR; Tumer, Z; Hong, HJ; Hougaard, DM; Huang, AY; Ibanez-Gomez, L. Polygenic risk score-based phenome-wide association study identifies novel associations for Tourette syndrome. Translational Psychiatry. 2023; 13:69.

Liu, R; Pedapati, EV; Schmitt, LM; Shaffer, RC; Smith, EG; Dominick, KC; DeStefano, LA; Westerkamp, G; Horn, P; Sweeney, JA; Erickson, CA. Reliability of resting-state electrophysiology in fragile X syndrome. Biomarkers in Neuropsychiatry. 2023; 9:100070.

Schmitt, LM; Smith, EG; Pedapati, EV; Horn, PS; Will, M; Lamy, M; Barber, L; Trebley, J; Meyer, K; Heiman, M; West, KH J; Hughes, P; Ahuja, S; Erickson, CA. Results of a phase Ib study of SB-121, an investigational probiotic formulation, a randomized controlled trial in participants with autism spectrum disorder. Scientific Reports. 2023; 13:5192.

Rahmatullah, N; Schmitt, LM; De Stefano, L; Post, S; Robledo, J; Chaudhari, GR; Pedapati, E; Erickson, CA; Portera-Cailliau, C; Goel, A. Hypersensitivity to Distractors in Fragile X Syndrome from Loss of Modulation of Cortical VIP Interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023; 43:8172-8188.

McGann, AM; Westerkamp, GC; Chalasani, A; Danzer, CS K; Parkins, EV; Rajathi, V; Horn, PS; Pedapati, EV; Tiwari, D; Danzer, SC; Gross, C. MiR-324-5p inhibition after intrahippocampal kainic acid-induced status epilepticus does not prevent epileptogenesis in mice. Frontiers in Neurology. 2023; 14:1280606.

Glazer, S; Parikh, N; Yuan, W; Pedapati, E; Chiu, P; Wade, S. 28 A Graph Theoretical Approach to Understanding Associations between Structural Connectivity and Improvements in Behavior of Children Born Very Preterm Following a Positive Parenting Intervention. Journal of the International Neuropsychological Society : JINS. 2023; 29:903-904.

Wilmshurst, JM; Catsman-Berrevoets, C; Gilbert, DL; Nagarajan, L; Samia, P; Serdaroglu, E; Triki, C; Vidaurre, J; Hameed, B. Access to Pediatric Neurology Training and Services Worldwide: A Survey by the International Child Neurology Association. Neurology. 2023; 101:798-808.

Batschelett, MA; Huddleston, DA; Crocetti, D; Horn, PS; Mostofsky, SH; Gilbert, DL. Biomarkers of tic severity in children with Tourette syndrome: Motor cortex inhibition measured with transcranial magnetic stimulation. Developmental Medicine and Child Neurology. 2023; 65:1321-1331.

Pedapati, EV. 53.2 Improvement in Depression and Fluid Cognition Following Accelerated Theta Burst Stimulation for Treatment-Resistant MDD in ASD. Journal of the American Academy of Child and Adolescent Psychiatry. 2023; 62:s407.

Pedapati, EV. 7.2 FROM GENES TO DIAGNOSIS: A PATIENT-CENTERED APPROACH TO MEDICAL GENETIC TESTING. Journal of the American Academy of Child and Adolescent Psychiatry. 2023; 62:s148-s149.

Jones, W; Klaiman, C; Richardson, S; Aoki, C; Smith, C; Minjarez, M; Bernier, R; Pedapati, E; Bishop, S; Ence, W; Wainer, A; Moriuchi, J; Tay, SW; Klin, A. Eye-Tracking-Based Measurement of Social Visual Engagement Compared With Expert Clinical Diagnosis of Autism. Journal of the American Medical Association (JAMA). 2023; 330:854-865.

Ethridge, LE; Auerbach, BD; Contractor, A; Ethell, IM; McCullagh, EA; Pedapati, EV. Editorial: Neural markers of sensory processing in development. Frontiers in Integrative Neuroscience. 2023; 17:1256437.

Martindale, JM; Sarva, H; Martino, D; Gilbert, DL; Ganos, C; Pringsheim, T; Black, K; Malaty, IA; Hallett, M; Hartmann, A; Smilowska, K; Szejko, N; van Wamelen, D; Worbe, Y. Study protocol: A cross-sectional survey of clinicians to identify barriers to clinical practice guideline implementation in the assessment and treatment of persistent tic disorders. Editor, Rashid TA. PloS one. 2023; 18:e0288408.

Neves, R; De Dios Perez, B; Panek, R; Jagani, S; Wilne, S; Bhatt, JM; Caputi, C; Cirillo, E; Coman, DJ; Dückers, G; Glazebrook, C; Suri, M; Whitehouse, WP; Dineen, RA. Development of cancer surveillance guidelines in ataxia telangiectasia: A Delphi-based consensus survey of international experts. Cancer Medicine. 2023; 12:14663-14673.

Doherty, AC; Huddleston, DA; Horn, PS; Ratner, N; Simpson, BN; Schorry, EK; Aschbacher-Smith, L; Prada, CE; Gilbert, DL. Motor Function and Physiology in Youth With Neurofibromatosis Type 1. Pediatric Neurology. 2023; 143:34-43.

Freidy, S; Dumitrescu, T; Schmith, V; Gilbert, D; Mahableshwarkar, A; Dubow, J; Cunniff, T; Kim, D; Miller, M; Wanaski, S. Increasing Ecopipam Exposure Improves Yale Global Tic Severity Scale-Total Tic Scores (YGTSS-TTS) in Children and Adolescents with Tourette Syndrome (TS): Results from a Population Pharmacokinetic (popPK) Model-Based Simulation Using D1AMOND Trial Data (P5-9.007). Neurology. 2023; 100.

Cunniff, T; Gilbert, D; Wanaski, S; Bittman, R; Dubow, J; Mahableshwarkar, A. Design of a Phase 3 Maintenance-of-Effect Trial of Ecopipam in Tourette Syndrome (P12-11.011). Neurology. 2023; 100.

Pringsheim, T; Ganos, C; Nilles, C; Cavanna, AE; Gilbert, DL; Greenberg, E; Hartmann, A; Hedderly, T; Heyman, I; Liang, H; Stern, J; Szejko, N; Worbe, Y; Martino, D. European Society for the Study of Tourette Syndrome 2022 criteria for clinical diagnosis of functional tic-like behaviours: International consensus from experts in tic disorders. European Journal of Neurology. 2023; 30:902-910.

Larsh, TR; Huddleston, DA; Horn, PS; Wu, SW; Cecil, KM; Jackson, HS; Edden, RA E; Mostofsky, SH; Gilbert, DL. From urges to tics in children with Tourette syndrome: associations with supplementary motor area GABA and right motor cortex physiology. Cerebral Cortex. 2023; 33:3922-3933.

Larsh, TR; Wu, SW; Huddleston, DA; White, S; Lipps, TD; Gilbert, DL. Adolescent Gender Differences in Tic- and Non-Tic-Related Impairments in Tourette Syndrome. Journal of Child Neurology. 2023; 38:283-289.

Norris, JE; Schmitt, LM; De Stefano, LA; Pedapati, EV; Erickson, CA; Sweeney, JA; Ethridge, LE. Neuropsychiatric feature-based subgrouping reveals neural sensory processing spectrum in female FMR1 premutation carriers: A pilot study. Frontiers in Integrative Neuroscience. 2023; 17:898215.

Martino, D; Hedderly, T; Murphy, T; Müller-Vahl, KR; Dale, RC; Gilbert, DL; Rizzo, R; Hartmann, A; Nagy, P; Anheim, M; Szejko, N; Han, VX; Kozlowska, K; Pringsheim, TM. The spectrum of functional tic-like behaviours: Data from an international registry. European Journal of Neurology. 2023; 30:334-343.

Zea Vera, A; Bruce, A; Larsh, TR; Jordan, Z; Brüggemann, N; Westenberger, A; Espay, AJ; Gilbert, DL; Wu, SW. Spectrum of Pediatric to Early Adulthood POLR3A-Associated Movement Disorders. Movement Disorders Clinical Practice. 2023; 10:316-322.

Gilbert, DL; Dubow, JS; Cunniff, TM; Wanaski, SP; Atkinson, SD; Mahableshwarkar, AR. Ecopipam for Tourette Syndrome: A Randomized Trial. Pediatrics. 2023; 151:e2022059574.

Schmitt, LM; Li, J; Liu, R; Horn, PS; Sweeney, JA; Erickson, CA; Pedapati, EV. Altered frontal connectivity as a mechanism for executive function deficits in fragile X syndrome. Molecular Autism. 2022; 13:47.

Norris, JE; Destefano, LA; Schmitt, LM; Pedapati, EV; Erickson, CA; Sweeney, JA; Ethridge, LE. Hemispheric Utilization of Alpha Oscillatory Dynamics as a Unique Biomarker of Neural Compensation in Females with Fragile X Syndrome. ACS Chemical Neuroscience. 2022; 13:3389-3402.

Pedapati, EV; Schmitt, LM; Ethridge, LE; Miyakoshi, M; Sweeney, JA; Liu, R; Smith, E; Shaffer, RC; Dominick, KC; Gilbert, DL; Binder, DK; Lamy, M; Axford, M; Erickson, CA. Neocortical localization and thalamocortical modulation of neuronal hyperexcitability contribute to Fragile X Syndrome. Communications Biology. 2022; 5:442.

Rosen, V; Blank, E; Lampert, E; Dominick, K; Will, M; Erickson, C; Pedapati, E; Lamy, M; Shaffer, R. Brief Report: Telehealth Satisfaction Among Caregivers of Pediatric and Adult Psychology and Psychiatry Patients with Intellectual and Developmental Disability in the Wake of Covid-19. Journal of Autism and Developmental Disorders. 2022; 52:5253-5265.

Jonak, CR; Pedapati, EV; Schmitt, LM; Assad, SA; Sandhu, MS; DeStefano, L; Ethridge, L; Razak, KA; Sweeney, JA; Binder, DK; Erickson, CA. Baclofen-associated neurophysiologic target engagement across species in fragile X syndrome. Journal of Neurodevelopmental Disorders. 2022; 14:52.

Radhakrishnan, R; Shea, LA G; Pruthi, S; Silvera, VM; Bosemani, T; Desai, NK; Gilbert, DL; Glenn, OA; Guimaraes, CV; Ho, ML; Udayasankar, UK; Whitehead, MT; Wright, JN; Rigsby, CK. ACR Appropriateness Criteria® Ataxia-Child. Journal of the American College of Radiology. 2022; 19:S240-S255.

Pedapati, E; Ethridge, L; Sweeney, J; Miyakoshi, M; Schmitt, L; Liu, R; Wu, S; Gilbert, D; Horn, P; Erickson, CA. THALAMOCORTICAL DYSRHYTHMIA AS A UNIFYING MODEL OF NEUROPSYCHIATRIC AND NEUROSENSORY DYSFUNCTION IN FRAGILE X SYNDROME. Journal of the American Academy of Child and Adolescent Psychiatry. 2022; 61:s275-s276.

Gelineau-Morel, R; Kruer, MC; Garris, JF; Abu Libdeh, A; Barbosa, DA N; Coffman, KA; Moon, D; Barton, C; Zea Vera, A; Bruce, AB; Larsh, T; Wu, SW; Gilbert, DL; O’Malley, JA. Deep Brain Stimulation for Pediatric Dystonia: A Review of the Literature and Suggested Programming Algorithm. Journal of Child Neurology. 2022; 37:813-824.

Pedapati, E. 82.1 Case Studies in Precision Medicine in Syndromic Intellectual Development Disorder. Journal of the American Academy of Child and Adolescent Psychiatry. 2022; 61:s114.

Larsh, TR; Wu, SW; Gilbert, DL. Comparison of Impairment in Functional Tic Disorders Versus Tourette Syndrome. Pediatric Neurology. 2022; 134:83-84.

Zhou, X; Feliciano, P; Shu, C; Wang, T; Astrovskaya, I; Hall, JB; Obiajulu, JU; Wright, JR; Murali, SC; Xu, SX; Cohen, C; Colombi, C; Diggins, C; Edmonson, C. Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes. Nature Genetics. 2022; 54:1305-1319.

Lapin, JE; Beal, SJ; Adams, RE; Ehrhardt, J; Pedapati, E; Froehlich, TE. Child Protective Custody Placement for Children with Developmental Disorders. Journal of Developmental and Behavioral Pediatrics. 2022; 43:418-426.

Marshall, CS; Deng, S; Jackson, HS; Horn, PS; Wolf, DS; Thompson-Stone, R; Gilbert, DL. Adult Neurology Rotations for Child Neurology Residents: A Survey of Program Directors. Neurology. 2022; 99:e858-e864.

Deng, S; Marshall, CS; Gilbert, DL; Jackson, HS; Wolf, DS; Thompson-Stone, R. Adult Neurology Rotations for Child Neurology Residents: Exploring the Resident Perspective. Pediatric Neurology. 2022; 133:34-39.

Yurkovic-Harding, J; Lisandrelli, G; Shaffer, RC; Dominick, KC; Pedapati, EV; Erickson, CA; Yu, C; Kennedy, DP. Children with ASD establish joint attention during free-flowing toy play without face looks. Current Biology. 2022; 32:2739-2746.e4.

He, JL; Hirst, RJ; Puri, R; Coxon, J; Byblow, W; Hinder, M; Skippen, P; Matzke, D; Heathcote, A; Wadsley, CG; Nikitenko, T; Zandbelt, B; Strickland, L; Puts, NA J. OSARI, an Open-Source Anticipated Response Inhibition Task. Behavior Research Methods. 2022; 54:1530-1540.

Larsh, T; Wu, S; Gilbert, D. Mini-Child Tourette Syndrome Impairment Scale Scores in Functional versus Primary Tic Disorders (P17-11.002). Neurology. 2022; 98.

Doherty, A; Huddleston, D; Jackson, H; Horn, P; Gilbert, D. Motor Cortex Inhibition: A Marker of Motor Function in Neurofibromatosis Type 1 (P16-6.005). Neurology. 2022; 98.

Zea Vera, A; Bruce, A; Garris, J; Tochen, L; Bhatia, P; Lehman, RK; Lopez, W; Wu, SW; Gilbert, DL. The Phenomenology of Tics and Tic-Like Behavior in TikTok. Pediatric Neurology. 2022; 130:14-20.

He, JL; Mikkelsen, M; Huddleston, DA; Crocetti, D; Cecil, KM; Singer, HS; Edden, RA E; Gilbert, DL; Mostofsky, SH; Puts, NA J. Frequency and Intensity of Premonitory Urges-to-Tic in Tourette Syndrome Is Associated With Supplementary Motor Area GABA+ Levels. Movement Disorders. 2022; 37:563-573.

Neilson, DE; Zech, M; Hufnagel, RB; Slone, J; Wang, X; Homan, S; Gutzwiller, LM; Leslie, EJ; Leslie, ND; Xiao, J; Eckenweiler, M; Winkelmann, J; Gilbert, DL; Huang, T. A Novel Variant of ATP5MC3 Associated with Both Dystonia and Spastic Paraplegia. Movement Disorders. 2022; 37:375-383.

Vera, AZ; Pedapati, EV; Larsh, TR; Kohmescher, K; Miyakoshi, M; Huddleston, DA; Jackson, HS; Gilbert, DL; Horn, PS; Wu, SW. EEG Correlates of Active Stopping and Preparation for Stopping in Chronic Tic Disorder. Brain Sciences. 2022; 12:151.

Schmitt, LM; Dominick, KC; Liu, R; Pedapati, EV; Ethridge, LE; Smith, E; Sweeney, JA; Erickson, CA. Evidence for Three Subgroups of Female FMR1 Premutation Carriers Defined by Distinct Neuropsychiatric Features: A Pilot Study. Frontiers in Integrative Neuroscience. 2022; 15:797546.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 11 Dystonia. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 14 Ataxia. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 19 Movement Disorders in Sleep. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 2 Cerebellar Anatomy, Biochemistry, Physiology, and Plasticity. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Movement Disorders in Childhood, Third Edition. London: Elsevier.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 10 Chorea, Athetosis, and Ballism. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 12 Myoclonus. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 20 Cerebral Palsy. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 8 Motor Stereotypies. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 22 Drug-Induced Movement Disorders in Children. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 18 Movement Disorders in Autoimmune Diseases. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 23 Functional Movement Disorders. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 4 Diagnostic Evaluation of Children With Movement Disorders. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 3 Classification of Movement Disorders. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 17 Metabolic Disorders With Associated Movement Abnormalities. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 16 Hereditary Spastic Paraplegia. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 15 Parkinsonism. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 6 Transient and Developmental Movement Disorders. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 13 Tremor. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 9 Paroxysmal Dyskinesias. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 21 Movement Disorders and Neuropsychiatric Conditions. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 7 Tics and Tourette Syndrome. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Chipkin, RE; Gilbert, DL; Mahableshwarkar, A. Ecopipam: A D1 receptor antagonist for the treatment of Tourette syndrome. The Neurobiology of the Gilles De La Tourette Syndrome and Chronic Tics - Part B. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 1 Basal Ganglia Anatomy, Biochemistry, and Physiology. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Singer, HS; Mink, JW; Gilbert, DL; Jankovic, J. Chapter 5 Motor Assessments. Movement Disorders in Childhood. : Elsevier; Elsevier; 2022.

Delgado, SV; Pedapati, EV; Strawn, JR. Promoting the Emotional and Behavioral Success of Youths, A Practical Guide for Clinicians.

Ewen, JB; Puts, NA; Mostofsky, SH; Horn, PS; Gilbert, DL. Associations between Task-Related Modulation of Motor-Evoked Potentials and EEG Event-Related Desynchronization in Children with ADHD. Cerebral Cortex. 2021; 31:5526-5535.

Pringsheim, T; Ganos, C; McGuire, JF; Hedderly, T; Woods, D; Gilbert, DL; Piacentini, J; Dale, RC; Martino, D. Rapid Onset Functional Tic-Like Behaviors in Young Females During the COVID-19 Pandemic. Movement Disorders. 2021; 36:2707-2713.

Halvorsen, M; Szatkiewicz, J; Mudgal, P; Yu, D; Nordsletten, AE; Mataix-Cols, D; Mathews, CA; Scharf, JM; Mattheisen, M; Robertson, MM; McQuillin, A; Crowley, JJ. Elevated common variant genetic risk for tourette syndrome in a densely-affected pedigree. Molecular Psychiatry. 2021; 26:7522-7529.

Yurkovic, JR; Lisandrelli, G; Shaffer, RC; Dominick, KC; Pedapati, EV; Erickson, CA; Kennedy, DP; Yu, C. Using head-mounted eye tracking to examine visual and manual exploration during naturalistic toy play in children with and without autism spectrum disorder. Scientific Reports. 2021; 11:3578.

Cao, X; Zhang, Y; Abdulkadir, M; Deng, L; Fernandez, TV; Garcia-Delgar, B; Hagstrøm, J; Hoekstra, PJ; King, RA; Koesterich, J; Dietrich, A; Tischfield, JA; Heiman, GA; Xing, J. Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families. Molecular Psychiatry. 2021; 26:6937-6951.

Abdulkadir, M; Yu, D; Osiecki, L; King, RA; Fernandez, TV; Brown, LW; Cheon, KA; Coffey, BJ; Garcia-Delgar, B; Gilbert, DL; Tischfield, JA; Heiman, GA; Dietrich, A; Hoekstra, PJ. Investigation of gene-environment interactions in relation to tic severity. Journal of Neural Transmission. 2021; 128:1757-1765.

Ganos, C; Sarva, H; Kurvits, L; Gilbert, DL; Hartmann, A; Worbe, Y; Mir, P; Müller-Vahl, KR; Münchau, A; Shprecher, D; Hallett, M; Tijssen, MA J; Pringsheim, T; Martino, D. Clinical Practice Patterns in Tic Disorders Among Movement Disorder Society Members. Tremor and Other Hyperkinetic Movements. 2021; 11:43.

Pedapati, E. 5.4 TRANSCRANIAL MAGNETIC STIMULATION MEASURES AS EMERGING BIOMARKERS OF ADHD IN AUTISM SPECTRUM DISORDER. Journal of the American Academy of Child and Adolescent Psychiatry. 2021; 60:s266.

Pedapati, E. 8.4 HURTLING TOWARD PRECISION MEDICINE IN SYNDROMIC INTELLECTUAL DISABILITY DISORDERS: INSIGHTS FROM MOUSE TO MAN. Journal of the American Academy of Child and Adolescent Psychiatry. 2021; 60:s137.

Peterson, AR; Garcia, TA; Cullion, K; Tiwari-Woodruff, SK; Pedapati, EV; Binder, DK. Targeted overexpression of glutamate transporter-1 reduces seizures and attenuates pathological changes in a mouse model of epilepsy. Neurobiology of Disease. 2021; 157:105443.

Larsh, T; Wu, SW; Vadivelu, S; Grant, GA; O'Malley, JA. Deep Brain Stimulation for Pediatric Dystonia. Seminars in Pediatric Neurology. 2021; 38:100896.

Tsetsos, F; Yu, D; Sul, JH; Huang, AY; Illmann, C; Osiecki, L; Darrow, SM; Hirschtritt, ME; Greenberg, E; Muller-Vahl, KR; Grice, DE; Hagstrøm, J; Hedderly, T; Heiman, GA. Synaptic processes and immune-related pathways implicated in Tourette syndrome. Translational Psychiatry. 2021; 11:56.

Smith, EG; Pedapati, EV; Liu, R; Schmitt, LM; Dominick, KC; Shaffer, RC; Sweeney, JA; Erickson, CA. Sex differences in resting EEG power in Fragile X Syndrome. Journal of Psychiatric Research. 2021; 138:89-95.

Harris, AD; Gilbert, DL; Horn, PS; Crocetti, D; Cecil, KM; Edden, RA E; Huddleston, DA; Mostofsky, SH; Puts, NA J. Relationship between GABA levels and task-dependent cortical excitability in children with attention-deficit/hyperactivity disorder. Clinical Neurophysiology. 2021; 132:1163-1172.

Deng, S; Marshall, C; Gilbert, D; Jackson, H; Wolf, D; Thompson-Stone, R. Adult Neurology Rotations for Child Neurology Residents: Exploring the Resident Perspective (2068). Neurology. 2021; 96.

Vera, AZ; Pedapati, E; Kohmescher, K; Miyakoshi, M; Huddleston, D; Jackson, H; Gilbert, D; Horn, P; Wu, S. EEG correlates of frontal cortex mediated inhibitory control in Tourette syndrome (1147). Neurology. 2021; 96.

Detrick, JA; Zink, C; Rosch, KS; Horn, PS; Huddleston, DA; Crocetti, D; Wu, SW; Pedapati, EV; Wassermann, EM; Mostofsky, SH; Gilbert, DL. Motor cortex modulation and reward in children with attention-deficit/hyperactivity disorder. Brain Communications. 2021; 3:fcab093.

Wink, LK; Reisinger, DL; Horn, P; Shaffer, RC; O'Brien, K; Schmitt, L; Dominick, KR; Pedapati, EV; Erickson, CA. Brief Report: Intranasal Ketamine in Adolescents and Young Adults with Autism Spectrum Disorder-Initial Results of a Randomized, Controlled, Crossover, Pilot Study. Journal of Autism and Developmental Disorders. 2021; 51:1392-1399.

Garris, JF; Huddleston, DA; Jackson, HS; Horn, PS; Gilbert, DL. Implementation of the Mini-Child Tourette Syndrome Impairment Scale: Relationships to Symptom Severity and Treatment Decisions. Journal of Child Neurology. 2021; 36:288-295.

Bruce, AB; Yuan, W; Gilbert, DL; Horn, PS; Jackson, HS; Huddleston, DA; Wu, SW. Altered frontal-mediated inhibition and white matter connectivity in pediatric chronic tic disorders. Experimental Brain Research. 2021; 239:955-965.

Zea Vera, A; Liu, W; Thomas, C; Gilbert, DL. Pearls & Oy-sters: A Novel Presentation of Ataxia With Vitamin E Deficiency Caused by TTPA Gene Mutation. Neurology. 2021; 96:e640-e642.

Miyakoshi, M; Schmitt, LM; Erickson, CA; Sweeney, JA; Pedapati, EV. Can We Push the "Quasi-Perfect Artifact Rejection " Even Closer to Perfection?. Frontiers in Neuroinformatics. 2021; 14:597079.

Rossi, S; Antal, A; Bestmann, S; Bikson, M; Brewer, C; Brockmöller, J; Carpenter, LL; Cincotta, M; Chen, R; Daskalakis, JD; Wassermann, EM; Zangen, A; Ziemann, U; Hallett, M. Safety and recommendations for TMS use in healthy subjects and patient populations, with updates on training, ethical and regulatory issues: Expert Guidelines. Clinical Neurophysiology. 2021; 132:269-306.