Mangano / Goto Lab

Publications

Wendelken, D; Ervin, B; Buroker, J; Scholle, C; Greiner, HM; Tenney, JR; Holland, KD; Skoch, J; Mangano, FT; Minai, A; Arya, R. Intracranial High-Frequency Oscillations and Epileptogenic Zone: Incorporating Neuroanatomic Variation. Journal of Clinical Neurophysiology. 2026; 43(2):129-138.

Vedala, K; Kadis, DS; Vannest, J; Sino, S; Horn, PS; Maue, E; Williamson, B; Mangano, FT; Leach, JL; Greiner, HM. Language Mapping With rTMS in Healthy Pediatric Patients. Journal of Clinical Neurophysiology. 2026; 43(1):68-78.

Larrew, T; Greiner, HM; Arya, R; Tenney, JR; Aungaroon, G; Clark, DJ; Vedala, K; Drake, AW; Leach, JL; Horn, PS; Skoch, J; Mangano, FT. Responsive Neurostimulation of Thalamic and Nonthalamic Targets in Pediatric and Young Adult Patients With Intractable Epilepsy. Neurosurgery. 2026; 98(1):204-210.

Tarcha, L; Krueger, DA; Greiner, HM; Skoch, J; Mangano, FT; Arya, R; Ihnen, SKZ. Electrical stimulation for the induction of seizures is safe, well-tolerated and high-yield in children with drug-resistant epilepsy. Epilepsy and Behavior. 2026; 174:110740.

Ervin, B; Agarwal, Y; Buroker, J; Scholle, C; Rozhkov, L; Cummins, T; Byars, AW; Horn, PS; Skoch, J; Mangano, FT; Holland, KD; Tenney, JR; Greiner, HM; Arya, R. Localization and duration dependent effects of pediatric refractory epilepsy on language function. Epilepsy and Behavior. 2026; 174:110813.

Ervin, B; Frink, C; Buroker, J; Horn, PS; Byars, AW; Scholle, C; Greiner, HM; Mangano, FT; Holland, KD; Hickok, G; Crone, NE; Arya, R. Behavior-iEEG-Spectral-Power-Correlation: Defining Neural Substrates of Naturalistic Behavior. Annals of Neurology. 2025; 98(5):1096-1110.

Saarinen, AJ; Andras, L; Boachie-Adjei, O; Cahill, P; Guillaume, T; Snyder, B; Sponseller, P; Sturm, P; Vitale, M; Helenius, I. High Preoperative Body Mass Index Is Associated With Implant Breakage in Patients Treated With Magnetically Controlled Growing Rods for Early-onset Scoliosis. Journal of Pediatric Orthopaedics. 2025; 45(8):492-498.

Ramirez, N; Acosta Julbe, JI; Smith, J; Emans, J; Samdani, A; Erickson, M; Flynn, J; Torres Lugo, NJ; Claudio-Marcano, AM; Olivella, G. How Does the Vertical Expandable Prosthetic Titanium Rib Lengthening Intervals Affect the Clinical Outcome in Early Onset Scoliosis Patients? A Five-Year Follow-Up Study. Journal of Pediatric Orthopaedics. 2025; 45(7):370-375.

Nagaraj, UD; Dudley, JA; Lam, K; Kline-Fath, BM; Merhar, SL; Mangano, FT; Yuan, W. Diffusion Tensor Imaging of Fetuses With Congenital Diaphragmatic Hernia. Prenatal Diagnosis. 2025; 45(8):1045-1052.

Miecznikowski, KB; Greiner, HM; Leach, J; Rozhkov, L; Mangano, FT; Krueger, DA; Difrancesco, MW. Prognostic application of lesion network mapping to epilepsy surgery outcomes in pediatric tuberous sclerosis complex. Epilepsia. 2025; 66(6):1854-1864.

Arya, R; Petito, GT; Housekeeper, J; Buroker, J; Scholle, C; Ervin, B; Frink, C; Horn, PS; Liu, W; Ruben, M; Smith, DF; Skoch, J; Mangano, FT; Greiner, HM; Holland, KD. Chronobiological Spatial Clusters of Cortical Regions in the Human Brain. Journal of Clinical Neurophysiology. 2025; 42(4):323-330.

Tenney, J; Fujiwara, H; Skoch, J; Horn, P; Hong, S; Lee, O; Kremer, K; Arya, R; Holland, K; Mangano, F; Greiner, H. User-defined virtual sensors: A new solution to the problem of temporal plus epilepsy sources. Epilepsia. 2025; 66(4):1071-1083.

Vedala, K; Aungaroon, G; Ritter, D; Greiner, HM; Tenney, JR; Skoch, J; Horn, PS; Leach, JL; Mangano, FT; Krueger, D; Arya, R. Altered cortical excitability in tuberous sclerosis and the effect of mTOR inhibitors: An intracranial electrical stimulation study. Clinical Neurophysiology. 2025; 172:1-9.

Ashebo, L; Sponseller, P; Hedequist, D; Ramirez, N; Oetgen, M; Li, Y. Outcomes of Growth-Friendly Surgical Treatment of Early Onset Scoliosis in Children With Prune Belly Syndrome: A Preliminary Report. Journal of Pediatric Orthopaedics. 2025; 45(4):212-219.

Hochstetler, A; Hehnly, C; Dawes, W; Harris, D; Sadegh, C; Mangano, FT; Lanjewar, SN; Chau, MJ. Research priorities for non-invasive therapies to improve hydrocephalus outcomes. Fluids and Barriers of the CNS. 2025; 22(1):24.

Iwasawa, E; Brown, FN; Shula, C; Emmert, AS; Fugate, EM; Lindquist, D; Mangano, FT; Goto, J. Suppression of microglial activation with anti-inflammatory drug bindarit enhances neural development in the shunt-treated neonatal hydrocephalus model rat. Experimental Neurology. 2025; 398:115608.

Daniel, A; Coronel, M; Peer, S; Grinshpan, B; Duru, S; Peiro, JL; Leach, JL; Abellán, E; Doerning, CM; Zarrouk, D; Mangano, FT. A novel minimally invasive neurosurgical cranial fixation device for improved accuracy of intraventricular catheter placement: an experimental animal study. Patient Safety in Surgery. 2024; 18(1):36.

Simon, TD; Hayati Rezvan, P; Coffin, SE; Hall, M; Hauptman, JS; Kronman, MP; Mangano, FT; Podkovik, S; Pollack, IF; Schaffzin, JK; Thorell, E; Warf, BC; Zhou, C; Whitlock, KB. Infection rates during eras of intrathecal antibiotic use followed by antibiotic-impregnated catheter use in prevention of cerebrospinal fluid shunt infection. Journal of Neurosurgery: Pediatrics. 2024; 34(4):357-364.

Ervin, B; Kargol, C; Byars, AW; Buroker, J; Rozhkov, L; Skoch, J; Mangano, FT; Greiner, HM; Horn, PS; Holland, K; Arya, R. High-gamma modulation language mapping and cognitive outcomes after epilepsy surgery. Epilepsia. 2024; 65(10):3052-3063.

Yuan, W; Stevenson, CB; Moretti, P; Mangano, FT; Pavanello, M; Cama, A; Tortora, D; Tacchino, C; Bailes, AF; Greve, KR; Harpster, K; Kurowski, BG; Mitelpunkt, A; Aronow, B. White matter characteristics in children with cerebral palsy prior to selective dorsal rhizotomy: a multicenter diffusion tensor imaging study. Journal of Neurosurgery: Pediatrics. 2024; 34(3):268-277.

Miecznikowski, KB; Leach, J; Rozhkov, L; Mangano, FT; Skoch, J; Krueger, DA; Horn, PS; Greiner, HM. Impact of seizure onset zone and intracranial electroencephalography ictal characteristics on epilepsy surgery outcomes in tuberous sclerosis complex. Epilepsy Research. 2024; 205:107422.

Yahanda, AT; Koueik, J; Ackerman, LL; Adelson, PD; Albert, GW; Aldana, PR; Alden, TD; Anderson, RCE; Bauer, DF; Bethel-Anderson, T; Whitehead, WE; Park, TS; Limbrick, DD; Ahmed, R. The role of occipital condyle and atlas anomalies on occipital cervical fusion outcomes in Chiari malformation type I with syringomyelia: a study from the Park-Reeves Syringomyelia Research Consortium. Journal of Neurosurgery: Pediatrics. 2024; 34(1):66-74.

Arya, R; Ervin, B; Greiner, HM; Buroker, J; Byars, AW; Tenney, JR; Arthur, TM; Fong, SL; Lin, N; Frink, C; Mangano, FT; Glauser, TA; Hickok, G; Holland, KD. Emotional facial expression and perioral motor functions of the human auditory cortex. Clinical Neurophysiology. 2024; 163:102-111.

Doherty, A; Knudson, K; Fuller, C; Leach, JL; Wang, AC; Marupudi, N; Han, RH; Tomko, S; Ojemann, J; Smyth, MD; Mangano, F; Skoch, J. MRI and pathology comparisons in Rasmussen's encephalitis: a multi-institutional examination of hemispherotomy outcomes relative to imaging and histological severity. Child's Nervous System. 2024; 40(6):1799-1806.

Podkovik, S; Zhou, C; Coffin, SE; Hall, M; Hauptman, JS; Kronman, MP; Mangano, FT; Pollack, IF; Sedano, S; Vega, J; Schaffzin, JK; Thorell, E; Warf, BC; Whitlock, KB; Simon, TD. Antibiotic impregnated catheters and intrathecal antibiotics for CSF shunt infection prevention in children undergoing low-risk CSF shunt surgery. BMC Pediatrics. 2024; 24(1):325.

Podkovik, S; Zhou, C; Coffin, SE; Hall, M; Hauptman, JS; Kronman, MP; Mangano, FT; Pollack, IF; Sedano, S; Schaffzin, JK; Thorell, E; Warf, BC; Whitlock, KB; Simon, TD. Utilization trends in cerebrospinal fluid shunt infection prevention techniques in the United States from 2007 to 2015. Journal of Neurosurgery: Pediatrics. 2024; 33(4):349-358.

Wissel, BD; Greiner, HM; Glauser, TA; Pestian, JP; Ficker, DM; Cavitt, JL; Estofan, L; Holland-Bouley, KD; Mangano, FT; Szczesniak, RD; Dexheimer, JW. Early Identification of Candidates for Epilepsy Surgery: A Multicenter, Machine Learning, Prospective Validation Study. Neurology. 2024; 102(4):e208048.

Roth, J; Bergman, L; Weil, AG; Brunette-Clement, T; Weiner, HL; Treiber, JM; Shofty, B; Cukiert, A; Cukiert, CM; Tripathi, M; Alsowat, D; Alotaibi, F; Ragheb, J; Uliel-Sibony, S. Added value of corpus callosotomy following vagus nerve stimulation in children with Lennox-Gastaut syndrome: A multicenter, multinational study. Epilepsia. 2023; 64(12):3205-3212.

Gaulden, AL; Trinidad, S; Moody, S; Kotagal, M; Mangano, FT; Patel, SK. Utility of the material community deprivation index as a metric to identify at-risk children for severe traumatic brain injury. Neurosurgical Focus. 2023; 55(5):E8.

Arya, R; Frink, C; Kargol, C; Byars, AW; Huddleston, D; Diedenhofer, DB; Aungaroon, G; Ervin, B; Horn, PS; Ihnen, SKZ; Mangano, FT; Glauser, TA; Greiner, HM; Holland, KD. Neuropsychological outcomes after epilepsy surgery: A comparison of stereo electroencephalography and subdural electrodes. European Journal of Neurology. 2023; 30(10):2986-2998.

Sedano, S; Kronman, MP; Whitlock, KB; Zhou, C; Coffin, SE; Hauptman, JS; Heller, E; Mangano, FT; Pollack, IF; Schaffzin, JK; Thorell, E; Warf, BC; Simon, TD. Associations of Standard Care, Intrathecal Antibiotics, and Antibiotic-Impregnated Catheters With Cerebrospinal Fluid Shunt Infection Organisms and Resistance. Journal of the Pediatric Infectious Diseases Society. 2023; 12(9):504-512.

Li, Y; Yang, D; Bergman, R; Jha, S; Casden, M; Smith, JT; Vitale, M; Heffernan, M. Preoperative left shoulder elevation > 1 cm is predictive of severe postoperative shoulder imbalance in early onset idiopathic scoliosis patients treated with growth-friendly instrumentation. Spine Deformity. 2023; 11(5):1157-1167.

Dudley, JA; Nagaraj, UD; Merhar, S; Mangano, FT; Kline-Fath, BM; Ou, X; Acheson, A; Yuan, W. DTI of Opioid-Exposed Fetuses Using ComBat Harmonization: A Bi-Institutional Study. American Journal of Neuroradiology. 2023; 44(9):1084-1089.

Greiner, HM; Maue, E; Horn, PS; Vannest, J; Vedala, K; Leach, JL; Tenney, JR; Williamson, B; Fujiwara, H; Coghill, RC; Mangano, FT; Kadis, DS. Tolerability of transcranial magnetic stimulation language mapping in children. Epilepsy Research. 2023; 194:107183.

Wissel, BD; Greiner, HM; Glauser, TA; Mangano, FT; Holland-Bouley, KD; Zhang, N; Szczesniak, RD; Santel, D; Pestian, JP; Dexheimer, JW. Automated, machine learning-based alerts increase epilepsy surgery referrals: A randomized controlled trial. Epilepsia. 2023; 64(7):1791-1799.

Aungaroon, G; Vedala, K; Byars, AW; Ervin, B; Rozhkov, L; Horn, PS; Ihnen, SKZ; Holland, KD; Tenney, JR; Kremer, K; Leach, JL; Mangano, FT; Greiner, HM; Arya, R. Comparing electrical stimulation functional mapping with subdural electrodes and stereoelectroencephalography. Epilepsia. 2023; 64(6):1527-1540.

Mena, R; Mendoza, E; Mangano, FT; Henrickson, M; Scott, M; Defoor, WR; Little, KJ; Ruschman, J; Prada, CE. International Pediatric Multidisciplinary Management Using Telemedicine to Promote Equitable Care. Telemedicine Journal and e-Health. 2023; 29(5):674-685.

Emmert, AS; Yahanda, AT; Limbrick, DD; Mangano, FT. 343 Influence of Duraplasty on Clinical, Radiological, and Surgical Factors Associated with Syrinx Location in Children Treated for Chiari Malformation Type I and Syringomyelia: A Park-Reeves Syringomyelia Research Consortium Study. Neurosurgery. 2023; 69(Supplement_1):54-54.

Arocho-Quinones, EV; Lew, SM; Handler, MH; Tovar-Spinoza, Z; Smyth, MD; Bollo, RJ; Donahue, D; Perry, MS; Levy, M; Gonda, D; Meola, A; Evanoff, W; Thompson, EM; Brandmeir, N. Magnetic resonance imaging-guided stereotactic laser ablation therapy for the treatment of pediatric epilepsy: a retrospective multiinstitutional study. Journal of Neurosurgery: Pediatrics. 2023; 1-14.

Patel, SK; Mangano, FT. Dandy-Walker Syndrome. In: Youmans and Winn Neurological Surgery Volumes 1 4 8th Edition. 2023:1636-1641.e1.

Brown, FN; Iwasawa, E; Shula, C; Fugate, EM; Lindquist, DM; Mangano, FT; Goto, J. Early postnatal microglial ablation in the Ccdc39 mouse model reveals adverse effects on brain development and in neonatal hydrocephalus. Fluids and Barriers of the CNS. 2023; 20(1):42.

Heyer, JH; Anari, JB; Baldwin, KD; Mitchell, SL; Luhmann, SJ; Sturm, PF; Flynn, JM; Cahill, PJ. Lengthening Behavior of Magnetically Controlled Growing Rods in Early-Onset Scoliosis: A Multicenter Study. Journal of Bone and Joint Surgery. American volume. 2022; 104(24):2186-2194.

Patel, SK; Gibson, JL; Lovha, M; Leach, JL; Arya, R; Tenney, JR; Holland, KD; Aungaroon, G; Greiner, HM; Skoch, J; Mangano, FT. Posterior Quadrant Disconnection Procedure for Intractable Epilepsy: A Case Series of 5 Young Pediatric Patients. Operative Neurosurgery. 2022; 23(6):449-456.

Holloway, T; Leach, JL; Tenney, JR; Byars, AW; Horn, PS; Greiner, HM; Mangano, FT; Holland, KD; Arya, R. Functional MRI and electrical stimulation mapping for language localization: A comparative meta-analysis. Clinical Neurology and Neurosurgery. 2022; 222:107417.

Hartnett, SM; Greiner, HM; Arya, R; Tenney, JR; Aungaroon, G; Holland, K; Leach, JL; Air, EL; Skoch, J; Mangano, FT. Responsive neurostimulation device therapy in pediatric patients with complex medically refractory epilepsy. Journal of Neurosurgery: Pediatrics. 2022; 30(5):499-506.

Petito, GT; Housekeeper, J; Buroker, J; Scholle, C; Ervin, B; Frink, C; Greiner, HM; Skoch, J; Mangano, FT; Dye, TJ; Hogenesch, JB; Glauser, TA; Holland, KD; Arya, R. Diurnal rhythms of spontaneous intracranial high-frequency oscillations. Seizure. 2022; 102:105-112.

Fujiwara, H; Kadis, DS; Greiner, HM; Holland, KD; Arya, R; Aungaroon, G; Fong, SL; Arthur, TM; Kremer, KM; Lin, N; Liu, W; Mangano, FT; Skoch, J; Horn, PS; Tenney, JR. Clinical validation of magnetoencephalography network analysis for presurgical epilepsy evaluation. Clinical Neurophysiology. 2022; 142:199-208.

Larrew, T; Skoch, J; Ihnen, SKZ; Arya, R; Holland, KD; Tenney, JR; Horn, PS; Leach, JL; Krueger, DA; Greiner, HM; Mangano, FT. Comparison of outcomes after stereoelectroencephalography and subdural grid monitoring in pediatric tuberous sclerosis complex. Neurosurgical Focus. 2022; 53(4):E5.

Mangano, FT; Altaye, M; Stevenson, CB; Yuan, W. The Construction of a Predictive Composite Index for Decision-Making of CSF Diversion Surgery in Pediatric Patients following Prenatal Myelomeningocele Repair. American Journal of Neuroradiology. 2022; 43(8):1214-1221.

Akbari, SHA; Yahanda, AT; Ackerman, LL; Adelson, PD; Ahmed, R; Albert, GW; Aldana, PR; Alden, TD; Anderson, RCE; Bauer, DF; Wellons, JC; Whitehead, WE; Park, TS; Limbrick, DD. Complications and outcomes of posterior fossa decompression with duraplasty versus without duraplasty for pediatric patients with Chiari malformation type I and syringomyelia: a study from the Park-Reeves Syringomyelia Research Consortium. Journal of Neurosurgery: Pediatrics. 2022; 30(1):39-51.

Mcmahon, R; Morgan, SJ; Brooks, JT; Cahill, P; Fitzgerald, R; Li, Y; Truong, WH. Does the presence of programmable implanted devices in patients with early onset scoliosis alter typical operative and postoperative practices? A survey of spine surgeons. Spine Deformity. 2022; 10(4):951-964.

Roth, J; Perekopaiko, Y; Kozyrev, DA; Constantini, S. Pediatric colloid cysts: a multinational, multicenter study. An IFNE-ISPN-ESPN collaboration. Journal of Neurosurgery: Pediatrics. 2022; 29(5):543-550.

Mishreky, A; Parent, S; Miyanji, F; Smit, K; Murphy, J; Bowker, R; Al Khatib, N; El-Hawary, R. Body mass index affects outcomes after vertebral body tethering surgery. Spine Deformity. 2022; 10(3):563-571.

Akbari, SHA; Rizvi, AA; Crevecoeur, TS; Han, RH; Greenberg, JK; Torner, J; Brockmeyer, DL; Wellons, JC; Leonard, JR; Mangano, FT; Smyth, MD; Dacey, RG; Park, TS; Limbrick, DD. Socioeconomic and demographic factors in the diagnosis and treatment of Chiari malformation type I and syringomyelia. Journal of Neurosurgery: Pediatrics. 2022; 29(3):288-297.

Sidler, E; Greiner, H; Mangano, F; Skoch, J; Arya, R; Holland, K; Aungaroon, G; Arthur, T; Fujiwara, H; Horn, P; Tenney, J. Improving Detection of Hippocampal Epileptiform Activity Using Magnetoencephalography. Journal of Clinical Neurophysiology. 2022; 39(3):240-246.

Harpster, K; Weckherlin, N; Engsberg, JR; Powell, SK; Barnard, H; Kadis, D; Dodd, JN; Garrett, M-L; Mangano, FT; Limbrick, DD; Altaye, M; Yuan, W. An iPad-based intervention to improve visual-motor, visual-attention, and visual-perceptual skills in children with surgically treated hydrocephalus: A pilot study. Child's Nervous System. 2022; 38(2):303-310.

Arya, R; Ervin, B; Buroker, J; Greiner, HM; Byars, AW; Rozhkov, L; Skoch, J; Horn, PS; Frink, C; Scholle, C; Leach, JL; Mangano, FT; Glauser, TA; Holland, KD. Neuronal Circuits Supporting Development of Visual Naming Revealed by Intracranial Coherence Modulations. Frontiers in Neuroscience. 2022; 16:867021.

Duy, PQ; Weise, SC; Marini, C; Li, X-J; Liang, D; Dahl, PJ; Ma, S; Spajic, A; Dong, W; Juusola, J; Lifton, RP; Sestan, N; Kolanus, W; Kahle, KT. Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus. Nature Neuroscience. 2022; 25(4):458-473.

Bedolla, A; Taranov, A; Luo, F; Wang, J; Turcato, F; Fugate, EM; Greig, NH; Lindquist, DM; Crone, SA; Goto, J; Luo, Y. Diphtheria toxin induced but not CSF1R inhibitor mediated microglia ablation model leads to the loss of CSF/ventricular spaces in vivo that is independent of cytokine upregulation. Journal of Neuroinflammation. 2022; 19(1):3.

Iwasawa, E; Brown, FN; Shula, C; Kahn, F; Lee, SH; Berta, T; Ladle, DR; Campbell, K; Mangano, FT; Goto, J. The Anti-Inflammatory Agent Bindarit Attenuates the Impairment of Neural Development through Suppression of Microglial Activation in a Neonatal Hydrocephalus Mouse Model. Journal of Neuroscience. 2022; 42(9):1820-1844.