Meet the Wells Lab

Eric Smith.

Eric Smith

Eric is an MD/PhD student pursuing his graduate training through the Cancer and Cell Biology program. He graduated from Rose-Hulman Institute of Technology with a BS in chemistry and biochemistry and molecular biology. Eric joined the Wells Lab after completing his second year of medical school. Eric studies the role of the DEK oncogene in DNA damage repair and is developing novel DEK-targeting approaches to enhance chemotherapy efficacy in head and neck carcinomas.

research image

Eric Smith.

Eric Smith

Marie Matrka.

Marie Matrka

Marie is a cancer and cell biology graduate student and joined the Wells Lab in 2011. Her focus of study is the DEK oncogene and its involvement in head and neck cancer and cancer cell metabolism.

Marie Matrka.

Marie Matrka.

Marie Matrka

Matt Sertorio.

Mathieu Sertorio

Mathieu performed his PhD research at the National Institute of Health and Medical Research in the Division of Immunology and Genetics of Parasitic Diseases, in Marseille, France. While there, he studied the human immune response to schistosomiasis, and genetic susceptibility to severe forms of the disease (liver fibrosis).

In 2012, Mathieu moved to Cincinnati Children’s to explore hematopoietic stem cell and immune deficiencies in the childhood disorder Fanconi anemia disease in the laboratory of Dr. Qishen Pang. His work demonstrated that the deregulation of WNT signaling in Fanconi deficient B cells leads to an impairment of cellular differentiation into plasma cells.

In 2015 Mathieu moved to the laboratory of Dr. Susanne Wells to spearhead basic research studies in the new Proton Therapy Center in collaboration with the Heidelberg Ion Beam Therapy Center (HIT, Germany, and Dr. Amir Abdollahi). There is a major gap between our sophisticated understanding of proton beam physics in clinical applications and a paucity of data on the molecular, cellular and tissue responses to radiation. The goal of Mathieu’s initiative is to bridge this gap, with the short term goal of leveraging novel transcriptomic and metabolomic profiling data into proton therapy biomarkers and treatment sensitizers.

Matt Sertorio.

Mathieu Sertorio

Marion Brusadelli.

Marion Brusadelli

Marion obtained her Master of Science in Biotechnology Engineering (Marseilles, France), majoring in biotechnology for health care. She joined the laboratory of Dr. Guasch in 2012 to study the regeneration and engineering of human sebaceous glands. She then joined the Wells team in 2014 as a laboratory manager. Her main project focuses on mechanisms of epidermal carcinogenesis in two- and three-dimensional human disease models in order to identify biomarkers of tumor susceptibility and new molecular targets. She works in close collaboration with ENT and oncology experts to engineer and analyze patient-specific models of pediatric recurrent respiratory papillomatosis (RRP).
Marion Brusadelli.

Marion Brusadelli

Sarah Haas.

Sarah Haas

Sarah Haas is an undergraduate student from Xavier University who joined the Wells laboratory in January of 2016 as a laboratory aide. Since then, she has been working with a graduate student, Marie Matrka. Sarah's research involves identifying phenotypes caused by Dek over-expression in a novel Dek transgenic mouse model.
Sarah Haas.

Sarah Haas

 Ruby Khoury.

Ruby Khoury

Ruby received her medical degree from the American University of Beirut and then completed her residency training in pediatric and adolescent medicine at Rainbow Babies and Children's Hospital at Cleveland. She joined Cincinnati Children's Hospital Medical Center in July 2015 to pursue a clinical fellowship in pediatric hematology/oncology. She joined the Wells lab in July 2016 and her area of interest is the biology of, and new therapies for, head and neck squamous cell carcinoma in patients with Fanconi Anemia.
Ruby Khoury.

Ruby Khoury

Nancy Echeverri.

Nancy Echeverri Ruiz

Nancy received her master’s degree in biochemistry sciences at the National University of Colombia; her research was based on proteomic analysis of thyroid papillary carcinomas in cooperation with the University of Santiago de Compostela, Spain. She moved to Miami University, Ohio, USA, to pursue her doctoral degree in tissue regeneration under the mentorship of Dr. Katia del Rio-Tsonis. In 2016, she moved to Cincinnati Children’s Hospital to study the metabolic role of the DEK oncoprotein in Dr. Susanne Wells’ laboratory.
Nancy Echeverri.

Nancy Echeverri Ruiz

Join the Lab

We welcome interested students and postdocs to join us in our research. For more information, please contact us.  Contact Us