Wells Lab

Sertorio, M; Perentesis, JP; Vatner, RE; Mascia, AE; Zheng, Y; Wells, SI. Cancer cell metabolism: Implications for x-ray and particle radiation therapy. International journal of particle therapy. 2019; 5:40-48.

Toptan, T; Brusadelli, MG; Turpin, B; Witte, DP; Surralles, J; Velleuer, E; Schramm, M; Dietrich, R; Brakenhoff, RH; Moore, PS; et al. Limited detection of human polyomaviruses in Fanconi anemia related squamous cell carcinoma. PLoS ONE. 2018; 13:e0209235-e0209235.

Zhao, X; Brusadelli, MG; Sauter, S; Kovacic, MB; Zhang, W; Romick-Rosendale, LE; Lambert, PF; Setchell, KD R; Wells, SI. Lipidomic Profiling Links the Fanconi Anemia Pathway to Glycosphingolipid Metabolism in Head and Neck Cancer Cells. Clinical Cancer Research. 2018; 24:2700-2709.

Matrka, MC; Cimperman, KA; Haas, SR; Guasch, G; Ehrman, LA; Waclaw, RR; Komurov, K; Lane, A; Wikenheiser-Brokamp, KA; Wells, SI. Dek overexpression in murine epithelia increases overt esophageal squamous cell carcinoma incidence. PLoS Genetics. 2018; 14:e1007227-e1007227.

Khoury, R; Sauter, S; Kovacic, MB; Nelson, AS; Myers, KC; Mehta, PA; Davies, SM; Wells, SI. Risk of Human Papillomavirus Infection in Cancer-Prone Individuals: What We Know. Viruses-Basel. 2018; 10:47-47.

Smith, EA; Krumpelbeck, EF; Jegga, AG; Prell, M; Matrka, MM; Kappes, F; Greis, KD; Ali, AM; Meetei, AR; Wells, SI. The nuclear DEK interactome supports multi-functionality. Proteins: Structure, Function, and Bioinformatics. 2018; 86:88-97.

Matrka, MC; Watanabe, M; Muraleedharan, R; Lambert, PF; Lane, AN; Romick-Rosendale, LE; Wells, SI. Overexpression of the human DEK oncogene reprograms cellular metabolism and promotes glycolysis. PLoS ONE. 2017; 12:e0177952-e0177952.

Smith, EA; Kumar, B; Komurov, K; Smith, SM; Brown, NV; Zhao, S; Kumar, P; Teknos, TN; Wells, SI. DEK associates with tumor stage and outcome in HPV16 positive oropharyngeal squamous cell carcinoma. Oncotarget. 2017; 8:23414-23426.

Smith, EA; Gole, B; Willis, NA; Soria, R; Starnes, LM; Krumpelbeck, EF; Jegga, AG; Ali, AM; Guo, H; Meetei, AR; et al. DEK is required for homologous recombination repair of DNA breaks. Scientific Reports. 2017; 7.

Chlon, TM; Ruiz-Torres, S; Maag, L; Mayhew, CN; Wikenheiser-Brokamp, KA; Davies, SM; Mehta, P; Myers, KC; Wells, JM; Wells, SI. Overcoming Pluripotent Stem Cell Dependence on the Repair of Endogenous DNA Damage. Stem Cell Reports. 2016; 6:44-54.

Marion, W; Boettcher, S; Ruiz-Torres, S; da Rocha, EL; Lundin, V; Morris, V; Chou, S; Zhao, AM; Kubaczka, C; Aumais, O; et al. An induced pluripotent stem cell model of Fanconi anemia reveals mechanisms of p53-driven progenitor cell differentiation. Blood Advances. 2020; 4:4679-4692.

Nowrouzi, A; Sertorio, MG; Akbarpour, M; Knoll, M; Krunic, D; Kuhar, M; Schwager, C; Brons, S; Debus, J; Wells, SI; et al. Personalized assessment of normal tissue radiosensitivity via transcriptome response to photon, proton and carbon irradiation in patient-derived human intestinal organoids. Cancers. 2020; 12:469-469.

van Harten, AM; Poell, JB; Buijze, M; Brink, A; Wells, SI; Leemans, CR; Wolthuis, RM F; Brakenhoff, RH. Characterization of a head and neck cancer-derived cell line panel confirms the distinct TP53-proficient copy number-silent subclass. Oral Oncology. 2019; 98:53-61.

Sertorio, M; Perentesis, JP; Vatner, RE; Mascia, AE; Zheng, Y; Wells, SI. Cancer cell metabolism: Implications for x-ray and particle radiation therapy. International journal of particle therapy. 2019; 5:40-48.

Nicol, AF; de Andrade, CV; Jr, GS C; Brusadellie, MG; Lodin, HM; Wells, SI; Nuovo, GJ. The distribution of novel biomarkers in carcinoma-in-situ, microinvasive, and squamous cell carcinoma of the uterine cervix. Annals of Diagnostic Pathology. 2019; 38:115-122.

Toptan, T; Brusadelli, MG; Turpin, B; Witte, DP; Surralles, J; Velleuer, E; Schramm, M; Dietrich, R; Brakenhoff, RH; Moore, PS; et al. Limited detection of human polyomaviruses in Fanconi anemia related squamous cell carcinoma. PLoS ONE. 2018; 13:e0209235-e0209235.

Trisno, SL; Philo, KE D; McCracken, KW; Cata, EM; Ruiz-Torres, S; Rankin, SA; Han, L; Nasr, T; Chaturvedi, P; Rothenberg, ME; et al. Esophageal Organoids from Human Pluripotent Stem Cells Delineate Sox2 Functions during Esophageal Specification. Cell Stem Cell. 2018; 23:501-515.e7.

Nuovo, GJ; de Andrade, CV; Wells, SI; Brusadelli, M; Nicol, AF. New biomarkers of human papillomavirus infection in acute cervical intraepithelial neoplasia. Annals of Diagnostic Pathology. 2018; 36:21-27.

Zhao, X; Brusadelli, MG; Sauter, S; Kovacic, MB; Zhang, W; Romick-Rosendale, LE; Lambert, PF; Setchell, KD R; Wells, SI. Lipidomic Profiling Links the Fanconi Anemia Pathway to Glycosphingolipid Metabolism in Head and Neck Cancer Cells. Clinical Cancer Research. 2018; 24:2700-2709.

Matrka, MC; Cimperman, KA; Haas, SR; Guasch, G; Ehrman, LA; Waclaw, RR; Komurov, K; Lane, A; Wikenheiser-Brokamp, KA; Wells, SI. Dek overexpression in murine epithelia increases overt esophageal squamous cell carcinoma incidence. PLoS Genetics. 2018; 14:e1007227-e1007227.

Serrano-Lopez, J; Nattamai, K; Pease, NA; Shephard, MS; Wellendorf, AM; Sertorio, M; Smith, EA; Geiger, H; Wells, SI; Cancelas, JA; et al. Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors. Experimental Hematology. 2018; 59:40-50.e3.

Khoury, R; Sauter, S; Kovacic, MB; Nelson, AS; Myers, KC; Mehta, PA; Davies, SM; Wells, SI. Risk of Human Papillomavirus Infection in Cancer-Prone Individuals: What We Know. Viruses-Basel. 2018; 10:47-47.

Smith, EA; Krumpelbeck, EF; Jegga, AG; Prell, M; Matrka, MM; Kappes, F; Greis, KD; Ali, AM; Meetei, AR; Wells, SI. The nuclear DEK interactome supports multi-functionality. Proteins: Structure, Function, and Bioinformatics. 2018; 86:88-97.

Mehta, PA; Sauter, S; Zhang, X; Davies, SM; Wells, SI; Myers, KC; Panicker, G; Unger, ER; Kovacic, MB. Antibody response to human papillomavirus vaccination and natural exposure in individuals with Fanconi Anemia. Vaccine. 2017; 35:6712-6719.

Myers, KC; Sauter, S; Zhang, X; Bleesing, JJ; Davies, SM; Wells, SI; Mehta, PA; Kumar, A; Marmer, D; Marsh, R; et al. Impaired immune function in children and adults with Fanconi anemia. Pediatric Blood and Cancer. 2017; 64:e26599-e26599.

Matrka, MC; Watanabe, M; Muraleedharan, R; Lambert, PF; Lane, AN; Romick-Rosendale, LE; Wells, SI. Overexpression of the human DEK oncogene reprograms cellular metabolism and promotes glycolysis. PLoS ONE. 2017; 12:e0177952-e0177952.

Smith, EA; Kumar, B; Komurov, K; Smith, SM; Brown, NV; Zhao, S; Kumar, P; Teknos, TN; Wells, SI. DEK associates with tumor stage and outcome in HPV16 positive oropharyngeal squamous cell carcinoma. Oncotarget. 2017; 8:23414-23426.

Smith, EA; Gole, B; Willis, NA; Soria, R; Starnes, LM; Krumpelbeck, EF; Jegga, AG; Ali, AM; Guo, H; Meetei, AR; et al. DEK is required for homologous recombination repair of DNA breaks. Scientific Reports. 2017; 7.

Koncar, RF; Chu, Z; Romick-Rosendale, LE; Wells, S; Chan, TA; Qi, X; Bahassi, EM. PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas. Oncotarget. 2017; 8:15827-15837.

Romick-Rosendale, LE; Hoskins, EE; Vinnedge, LM P; Foglesong, GD; Brusadelli, MG; Potter, SS; Komurov, K; Brugmann, SA; Lambert, PF; Kimple, RJ; et al. Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling. Clinical Cancer Research. 2016; 22:2062-2073.

Chlon, TM; Ruiz-Torres, S; Maag, L; Mayhew, CN; Wikenheiser-Brokamp, KA; Davies, SM; Mehta, P; Myers, KC; Wells, JM; Wells, SI. Overcoming Pluripotent Stem Cell Dependence on the Repair of Endogenous DNA Damage. Stem Cell Reports. 2016; 6:44-54.