Wells Lab

Zhao, X; Brusadelli, MG; Sauter, S; Kovacic, MB; Zhang, W; Romick-Rosendale, LE; Lambert, PF; Setchell, KD R; Wells, SI. Lipidomic Profiling Links the Fanconi Anemia Pathway to Glycosphingolipid Metabolism in Head and Neck Cancer Cells. Clinical Cancer Research. 2018; 24:2700-2709.

Khoury, R; Sauter, S; Kovacic, MB; Nelson, AS; Myers, KC; Mehta, PA; Davies, SM; Wells, SI. Risk of Human Papillomavirus Infection in Cancer-Prone Individuals: What We Know. Viruses-Basel. 2018; 10:47-47.

Myers, KC; Sauter, S; Zhang, X; Bleesing, JJ; Davies, SM; Wells, SI; Mehta, PA; Kumar, A; Marmer, D; Marsh, R; et al. Impaired immune function in children and adults with Fanconi anemia. Pediatric Blood and Cancer. 2017; 64:e26599-e26599.

Matrka, MC; Watanabe, M; Muraleedharan, R; Lambert, PF; Lane, AN; Romick-Rosendale, LE; Wells, SI. Overexpression of the human DEK oncogene reprograms cellular metabolism and promotes glycolysis. PLoS ONE. 2017; 12:e0177952-e0177952.

Smith, EA; Kumar, B; Komurov, K; Smith, SM; Brown, NV; Zhao, S; Kumar, P; Teknos, TN; Wells, SI. DEK associates with tumor stage and outcome in HPV16 positive oropharyngeal squamous cell carcinoma. Oncotarget. 2017; 8:23414-23426.

Smith, EA; Gole, B; Willis, NA; Soria, R; Starnes, LM; Krumpelbeck, EF; Jegga, AG; Ali, AM; Guo, H; Meetei, AR; et al. DEK is required for homologous recombination repair of DNA breaks. Scientific Reports. 2017; 7.

Koncar, RF; Chu, Z; Romick-Rosendale, LE; Wells, S; Chan, TA; Qi, X; Bahassi, EM. PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas. Oncotarget. 2017; 8:15827-15837.

Romick-Rosendale, LE; Hoskins, EE; Vinnedge, LM P; Foglesong, GD; Brusadelli, MG; Potter, SS; Komurov, K; Brugmann, SA; Lambert, PF; Kimple, RJ; et al. Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling. Clinical Cancer Research. 2016; 22:2062-2073.

Tuttle, TR; Mierzwa, ML; Wells, SI; Fox, SR; Ben-Jonathan, N. The cyclic GMP/protein kinase G pathway as a therapeutic target in head and neck squamous cell carcinoma. Cancer Letters. 2016; 370:279-285.

Chlon, TM; Ruiz-Torres, S; Maag, L; Mayhew, CN; Wikenheiser-Brokamp, KA; Davies, SM; Mehta, P; Myers, KC; Wells, JM; Wells, SI. Overcoming Pluripotent Stem Cell Dependence on the Repair of Endogenous DNA Damage. Stem Cell Reports. 2016; 6:44-54.

Adams, AK; Bolanos, LC; Dexheimer, PJ; Karns, RA; Aronow, BJ; Komurov, K; Jegga, AG; Casper, KA; Patil, YJ; Wilson, KM; et al. IRAK1 is a novel DEK transcriptional target and is essential for head and neck cancer cell survival. Oncotarget. 2015; 6:43395-43407.

Matrka, MC; Hennigan, RF; Kappes, F; DeLay, ML; Lambert, PF; Aronow, BJ; Wells, SI. DEK over-expression promotes mitotic defects and micronucleus formation. Cell Cycle. 2015; 14:3939-3953.

Smith, EA; Matrka, MC; Wells, SI. HPV virology: Cellular targets of HPV oncogenes and transformation. Human Papillomavirus (HPV)-Associated Oropharyngeal Cancer. : Springer International Publishing; Springer International Publishing; 2015.

Sauter, SL; Wells, SI; Zhang, X; Hoskins, EE; Davies, SM; Myers, KC; Mueller, R; Panicker, G; Unger, ER; Sivaprasad, U; et al. Oral Human Papillomavirus Is Common in Individuals with Fanconi Anemia. Cancer Epidemiology, Biomarkers and Prevention. 2015; 24:864-872.

Vinnedge, LM P; Benight, NM; Wagh, PK; Pease, NA; Nashu, MA; Serrano-Lopez, J; Adams, AK; Cancelas, JA; Waltz, SE; Wells, SI. The DEK oncogene promotes cellular proliferation through paracrine Wnt signaling in Ron receptor-positive breast cancers. Oncogene: Including Oncogene Reviews. 2015; 34:2325-2336.

Lombardi, AJ; Hoskins, EE; Foglesong, GD; Wikenheiser-Brokamp, KA; Wiesmueller, L; Hanenberg, H; Andreassen, PR; Jacobs, AJ; Olson, SB; Keeble, WW; et al. Acquisition of Relative Interstrand Crosslinker Resistance and PARP Inhibitor Sensitivity in Fanconi Anemia Head and Neck Cancers. Clinical Cancer Research. 2015; 21:1962-1972.

Adams, AK; Hallenbeck, GE; Casper, KA; Patil, YJ; Wilson, KM; Kimple, RJ; Lambert, PF; Witte, DP; Xiao, W; Gillison, ML; et al. DEK promotes HPV-positive and -negative head and neck cancer cell proliferation. Oncogene: Including Oncogene Reviews. 2015; 34:868-877.