Wu Lab

Publications

Wu, PV; Fish, M; Hazard, FK; Zhu, C; Vennam, S; Walton, H; Wagh, D; Coller, J; Przybyl, J; Morri, M; Neff, N; West, RB; Nusse, R. A developmental biliary lineage program cooperates with Wnt activation to promote cell proliferation in hepatoblastoma. Nature Communications. 2024; 15(1):10007.

Wu, PV; Fish, M; Hazard, FK; Zhu, C; Vennam, S; Walton, H; Przybyl, J; Morri, M; Neff, N; West, RB; Nusse, R. Abstract B024: Single cell transcriptomics and patient-derived tumoroids reveal that hepatobiliary lineage programs cooperate with Wnt pathway mutations to drive cell proliferation in hepatoblastoma. Cancer Research. 2024; 84(17_Supplement):b024-b024.

Bouju, A; Nusse, R; Wu, PV. A primer on the pleiotropic endocrine fibroblast growth factor FGF19/FGF15. Differentiation. 2024; 140:100816.

Myler, LR; Toia, B; Vaughan, CK; Takai, K; Matei, AM; Wu, P; Paull, TT; De Lange, T; Lottersberger, F. DNA-PK and the TRF2 iDDR inhibit MRN-initiated resection at leading-end telomeres. Nature Structural & Molecular Biology. 2023; 30(9):1346-1356.

Sarkar, A; Jin, Y; Defelice, BC; Logan, CY; Yang, Y; Anbarchian, T; Wu, P; Morri, M; Neff, NF; Nguyen, H; Rulifson, E; Fish, M; Kaye, AG; Martínez Jaimes, AM; Nusse, R. Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver. eLife. 2023; 12.

Wu, PV; Rangaswami, A. Current Approaches in Hepatoblastoma-New Biological Insights to Inform Therapy. Current Oncology Reports. 2022; 24(9):1209-1218.

Jin, Y; Anbarchian, T; Wu, P; Sarkar, A; Fish, M; Peng, WC; Nusse, R. Wnt signaling regulates hepatocyte cell division by a transcriptional repressor cascade. Proceedings of the National Academy of Sciences of the United States of America. 2022; 119(30):e2203849119.

Wu, PV; Nusse, R. 3D Culture of Primary Patient-Derived Hepatoblastoma Tumoroids. 2022:259-267.

Wu, P; Takai, H; De Lange, T. Telomeric 3' overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST. Cell. 2012; 150(1):39-52.