Mizuno Lab

Publications

Morales Junior, R; Hambrick, HR; Benoit, SW; Klink, G; Mizuno, T; Tang Girdwood, S. Population pharmacokinetics and Monte Carlo simulation of Cefepime in paediatric and Young adult bone marrow transplant patients. British Journal of Clinical Pharmacology. 2026.

Pais, GM; Lesnicki, E; Marianski, S; Valdez, K; Gibson, Z; Christopher, J; Lepard, K; Gilchrist, A; Mizuno, T; Scheetz, MH. Elevated hippocampal and cortical cefepime concentrations correlate with seizures in an acute kidney injury rat model. Antimicrobial Agents and Chemotherapy. 2026; e0100525.

Hambrick, HR; Junior, RM; Curry, C; Collins, M; Johnson, L; Mizuno, T; Krallman, KA; Goldstein, SL; Girdwood, ST. Urine NGAL Adds to Serum Creatinine in Predicting Cefepime Clearance in Critically Ill Children at High Risk of Acute Kidney Injury. International Journal of Antimicrobial Agents. 2026; 107741.

Irie, K; Minar, P; Reifenberg, J; Boyle, BM; Noe, JD; Hyams, JS; Mizuno, T. Machine Learning Modeling for Predicting Infliximab Pharmacokinetics in Pediatric and Young Adult Patients With Crohn Disease: Leveraging Ensemble Modeling With Synthetic and Real-World Data. Therapeutic Drug Monitoring. 2026; 48(1):98-104.

Umemura, K; Katsube, Y; Tsuchido, Y; Katada, Y; Hira, D; Kawata, M; Saigo, M; Tsuda, M; Nakagawa, S; Hattori, EY; Arakawa, Y; Date, H; Nagao, M; Terada, T. Efficient Penetration of Terbinafine into Brain Abscesses in a Lung Transplant Recipient with Scedosporiosis: A Short Communication. Therapeutic Drug Monitoring. 2026; 48(1):134-139.

Irie, K; Minar, P; Reifenberg, J; Boyle, BM; Noe, JD; Hyams, JS; Mizuno, T. Model-Informed Deep Q-Networks to Guide Infliximab Dosing in Pediatric Crohn's Disease. Clinical Pharmacology and Therapeutics. 2026; 119(2):555-563.

Mizuno, T; Neely, MN. Rising Role of Artificial Intelligence in Clinical Pharmacometrics and Model-Informed Precision Dosing in Pediatrics. Journal of Pediatric Pharmacology and Therapeutics. 2026; 31(1):106-111.

Morales Junior, R; Mizuno, T; Tan, WR; Irie, K; Tang Girdwood, S. From PICU to NICU: Extrapolating Meropenem Exposure From Pediatric to Neonatal Intensive Care Patients. Journal of Clinical Pharmacology. 2026; 66(1):e70097.

Burlo, F; Pastore, S; Stocco, G; Zuanna, PD; Curci, D; Mizuno, T; Irie, K; Taddio, A; Tommasini, A. Give weekly adalimumab a chance before discontinuing it: a retrospective clinical and pharmacokinetic analysis in pediatric rheumatology. Arthritis Research & Therapy. 2025; 27(1):230.

Ogawa-Iio, A; Takeuchi, K; Shigemi, K; Genoveso, MJ; Niitsu, H; Koh, I; Ota, Y; Yamane, K; Hinoi, T; Osaka, N; Goyama, S; Yasuda, T; Senda, T; Sasaki, AT. IMPDH and GTP Metabolism in Cancer: Mechanisms, Regulation, and Translational Scope. Cancer Science. 2025; 116(12):3250-3265.

Tang Girdwood, S; Morales Junior, R; Schuler, E; Tang, P; Diseroad, E; Misch, C; Engle, B; Mccall, S; Murphy, ME; Taylor, ZL; Mizuno, T; Vinks, AA; Kaplan, J. Building a Beta-Lactam Model-Informed Precision Dosing Service in a Quaternary Care Children's Hospital. Clinical and Translational Science. 2025; 18(12):e70438.

Ritter, DM; Schneider, K; Ezeakudo, N; Krueger, DA; Mizuno, T; Knilans, TK; Franz, DN. Maternal Sirolimus Treatment Reverses Cardiac Rhabdomyoma-Induced Hydrops Fetalis in a Twin Gestation With Tuberous Sclerosis Complex. American Journal of Medical Genetics, Part A. 2025; 197(11):e64175.

Irie, K; Minar, P; Reifenberg, J; Boyle, BM; Noe, JD; Hyams, JS; Mizuno, T. Hybrid Population Pharmacokinetic-Machine Learning Modeling to Predict Infliximab Pharmacokinetics in Pediatric and Young Adult Patients with Crohn's Disease. Clinical Pharmacokinetics. 2025; 64(11):1669-1679.

Sawada, K; Khandelwal, P; Davies, SM; Crooker, A; Mizuno, T; Asai, A. Pharmacokinetic Monitoring of JAK Inhibitor and Tacrolimus for Safe and Effective Management of Graft-Versus-Host Disease After Pediatric Liver Transplantation. Pediatric Transplantation. 2025; 29(7):e70187.

Pyatt, A; Mcgowan, M; Tanaka, R; Miyagawa, B; Mizuno, T; Shields, AR; Christianson, A; West-Thielke, P; Leone, JP; Woodle, ES; Kaufman, D; Wiseman, A; Matas, AJ; Vinks, AA; Alloway, RR. Belatacept Pharmacokinetic Analysis of Belatacept Early Steroid Withdrawal Trial (BEST) to Clinical Outcomes and Compared With Reported BENEFIT and BENEFIT-EXT Pharmacokinetic Analysis. Clinical Transplantation. 2025; 39(8):e70172.

Zhao, J; Zhao, X; Mizuno, T; Irie, K; Devarajan, P; Brunner, HI; Setchell, KDR. Volumetric Absorptive Microsampling Combined with Mass Spectrometry to Support Pharmacokinetically-Guided Precision Dosing of Mycophenolate Mofetil in Pediatric Lupus Nephritis Patients. Journal of Applied Laboratory Medicine. 2025; 10(4):806-819.

Tanaka, R; Irie, K; Mizuno, T. Physiologically Based Pharmacokinetic Modeling of Antibiotics in Children: Perspectives on Model-Informed Precision Dosing. Antibiotics. 2025; 14(6).

Morales Junior, R; Hambrick, HR; Mizuno, T; Pavia, KE; Paice, KM; Tang, P; Schuler, E; Krallman, KA; Johnson, L; Collins, M; Gibson, A; Curry, C; Kaplan, J; Goldstein, S; Tang Girdwood, S. Population Pharmacokinetics of Cefepime in Critically Ill Children and Young Adults: Model Development and External Validation for Monte Carlo Simulations and Model-Informed Precision Dosing. Clinical Pharmacokinetics. 2025; 64(4):553-564.

Tan, WR; Irie, K; Mcintire, C; Torres, JL; Jones, R; Gibson, A; Mizuno, T; Tang Girdwood, S. Model-informed dose optimization for prophylactic piperacillin-tazobactam in perioperative pediatric critically ill patients. Antimicrobial Agents and Chemotherapy. 2025; 69(3):e0122724.

Bartel, C; Mizuno, T; Irie, K; Samuels, A; Lynch, K; Jackson, K; Hyams, J; Boyle, B; Saeed, S; Kurowski, J; Noe, J; Chun, K; Yang, J; Denson, L; Minar, P. AN EVALUATION OF ENDOSCOPIC HEALING IN PEDIATRIC CROHN’S DISEASE USING MULTIPLE ENDOSCOPIC SCORING METHODS IDENTIFIES SIMILARITIES IN BLOOD AND STOOL BIOMARKERS. Inflammatory Bowel Diseases. 2025; 31(Supplement_1):s59-s60.

Pavia, K; Girdwood, ST; Paice, K; Dong, M; Mizuno, T; Tang, P; Mangeot, C; Vinks, AA; Kaplan, J. Acute kidney injury is associated with abnormal cefepime exposure among critically ill children and young adults. Pediatric Nephrology. 2025; 40(2):513-521.

Masuda, S; Lemaitre, F; Barten, MJ; Bergan, S; Shipkova, M; Van Gelder, T; Vinks, S; Wieland, E; Bornemann-Kolatzki, K; Brunet, M; Venkataramanan, R; Walson, P; Woillard, J-B; Langman, LJ. Everolimus Personalized Therapy: Second Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology. Therapeutic Drug Monitoring. 2025; 47(1):4-31.

Samuels, A; Irie, K; Mizuno, T; Reifenberg, J; Punt, N; Vinks, AA; Minar, P. Integrating early response biomarkers in pharmacokinetic models: A novel method to individualize the initial infliximab dose in patients with Crohn's disease. Clinical and Translational Science. 2025; 18(2):e70086.

Bartel, C; Mizuno, T; Irie, K; Samuels, A; Lynch, K; Jackson, K; Hyams, J; Boyle, B; Saeed, S; Kurowski, J; Noe, J; Chun, K; Yang, J; Denson, L; Minar, P. AN EVALUATION OF ENDOSCOPIC HEALING IN PEDIATRIC CROHN’S DISEASE USING MULTIPLE ENDOSCOPIC SCORING METHODS IDENTIFIES SIMILARITIES IN BLOOD AND STOOL BIOMARKERS. Gastroenterology. 2025; 168(3):s84-s85.

Katsube, Y; Umemura, K; Urabe, Y; Ono, M; Katada, Y; Hira, D; Ohsumi, A; Nakajima, D; Tsuda, M; Nakagawa, S; Mizuno, T; Nagao, M; Date, H; Terada, T. NUDT15 Genetic Polymorphism as a Risk Factor for Early Neutropenia During Valganciclovir Prophylaxis in Lung Transplant Patients. Transplant Infectious Disease. 2025; 27(6):e70108.

Paice, K; Tang Girdwood, S; Mizuno, T; Pavia, K; Punt, N; Tang, P; Dong, M; Curry, C; Jones, R; Gibson, A; Vinks, AA; Kaplan, J. Pharmacokinetic Factors Associated With Early Meropenem Target Attainment in Pediatric Severe Sepsis. Pediatric Critical Care Medicine. 2024; 25(12):1103-1116.

Hambrick, HR; Punt, N; Pavia, K; Mizuno, T; Goldstein, SL; Tang Girdwood, S. Monte Carlo simulations of cefepime in children receiving continuous kidney replacement therapy support continuous infusions for target attainment. Journal of Intensive Care. 2024; 12(1):38.

Morales Junior, R; Mizuno, T; Paice, KM; Pavia, KE; Hambrick, HR; Tang, P; Jones, R; Gibson, A; Stoneman, E; Curry, C; Kaplan, J; Tang Girdwood, S. Identifying optimal dosing strategies for meropenem in the paediatric intensive care unit through modelling and simulation. Journal of Antimicrobial Chemotherapy. 2024; 79(10):2668-2677.

Morales, R; Mizuno, T; Paice, KM; Hambrick, HR; Punt, N; Tang Girdwood, S. Impact of fluid balance on beta-lactam antibiotics target attainment: Insights from a simulation-based meropenem study. International Journal of Antimicrobial Agents. 2024; 64(3):107267.

Minichmayr, IK; Mizuno, T; Goswami, S; Peck, RW; Polasek, TM. Recent Advances Addressing the Challenges of Precision Dosing. Clinical Pharmacology and Therapeutics. 2024; 116(3):527-530.

Power-Hays, A; Dong, M; Punt, N; Mizuno, T; Smart, LR; Vinks, AA; Ware, RE. Rationale, Development, and Validation of HdxSim, a Clinical Decision Support Tool for Model-Informed Precision Dosing of Hydroxyurea for Children with Sickle Cell Anemia. Clinical Pharmacology and Therapeutics. 2024; 116(3):670-677.

Paice, K; Tang Girdwood, S; Mizuno, T; Pavia, K; Punt, N; Tang, P; Dong, M; Curry, C; Jones, R; Gibson, A; Vinks, AA; Kaplan, J. Pharmacokinetic Factors Associated With Early Meropenem Target Attainment in Pediatric Severe Sepsis. Lippincott Williams & Wilkins. Aug 20, 2024.

Wilson, NK; Tremblay, S; Shields, AR; Woodle, ES; Alloway, RR; Vinks, AA; Miyagawa, B; Mizuno, T. Belatacept Removal by Plasmapheresis: Dose Adjustments and Clinical Recommendations. Transplantation Direct. 2024; 10(8):e1677.

Van Hoogdalem, MW; Tanaka, R; Johnson, TN; Vinks, AA; Mizuno, T. Development and Verification of a Full Physiologically Based Pharmacokinetic Model for Sublingual Buprenorphine in Healthy Adult Volunteers that Accounts for Nonlinear Bioavailability. Drug Metabolism And Disposition. 2024; 52(8):785-796.

Hambrick, HR; Fei, L; Pavia, K; Kaplan, J; Mizuno, T; Tang, P; Schuler, E; Benoit, S; Girdwood, ST. Cystatin C Outperforms Creatinine in Predicting Cefepime Clearance in Pediatric Stem Cell Transplant Recipients. Transplantation and Cellular Therapy. 2024; 30(6):614.e1-614.e11.

Capal, JK; Ritter, DM; Franz, DN; Griffith, M; Currans, K; Kent, B; Bebin, EM; Northrup, H; Koenig, MK; Mizuno, T; Greiner, HM; Holland-Bouley, K; Horn, PS; Krueger, DA. Preventative treatment of tuberous sclerosis complex with sirolimus: Phase I safety and efficacy results. Annals of the Child Neurology Society. 2024; 2(2):106-119.

Alsoud, D; Moes, DJAR; Wang, Z; Soenen, R; Layegh, Z; Barclay, M; Mizuno, T; Minichmayr, IK; Keizer, RJ; Wicha, SG; De Vries, A; Papamichael, K; Padullés-Zamora, N; Dreesen, E. Best Practice for Therapeutic Drug Monitoring of Infliximab: Position Statement from the International Association of Therapeutic Drug Monitoring and Clinical Toxicology. Therapeutic Drug Monitoring. 2024; 46(3):291-308.

Yamashita, Y; Hira, D; Morita, M; Katsube, Y; Takakura, M; Tomotaki, H; Tomotaki, S; Xiong, W; Shiomi, H; Horie, T; Ueshima, S; Mizuno, T; Terada, T; Ono, K. Potential treatment option of rivaroxaban for breastfeeding women: A case series. Thrombosis Research. 2024; 237:141-144.

Nasr, A; Mizuno, T; Irie, K; Dillman, J; Jackson, K; Lynch, K; Horrell, A; Chun, KY; Yang, JM; Hyams, JS; Boyle, BM; Noe, JD; Denson, LA; Minar, PP. 958 ATTAINING EARLY ANTI-TNF EXPOSURE TARGETS IS ASSOCIATED WITH IMPROVED RATES OF ENDOSCOPIC HEALING AND TRANSMURAL HEALING IN CHILDREN WITH CROHN'S DISEASE. Gastroenterology. 2024; 166(5):s-226-s-227.

Hambrick, HR; Cervantes, F; Dong, M; Tang, P; Arbough, T; Vinks, AA; Mizuno, T; Goldstein, SL; Kaplan, J; Girdwood, ST. Ceftriaxone Pharmacokinetics and Pharmacodynamic Target Attainment for Three Pediatric Patients Receiving Continuous Kidney Replacement Therapy. Journal of Pediatric Pharmacology and Therapeutics. 2024; 29(2):180-187.

Strawn, JR; Poweleit, EA; Taylor, ZL; Mizuno, T; Vaughn, S; Desta, Z; Stancil, S; Ramsey, LB. 84 Using Opportunistic Sampling and Remnant Blood Samples to Develop Pediatric Pharmacokinetic Models to Inform Antidepressant Dosing. Journal of Clinical and Translational Science. 2024; 8(s1):22-23.

Minar, PP; Colman, RJ; Zhang, N; Mizuno, T; Vinks, AA. Precise infliximab exposure and pharmacodynamic control to achieve deep remission in paediatric Crohn's disease (REMODEL-CD): study protocol for a multicentre, open-label, pragmatic clinical trial in the USA. BMJ Open. 2024; 14(3):e077193.

Van Hoogdalem, MW; Tanaka, R; Abduljalil, K; Johnson, TN; Wexelblatt, SL; Akinbi, HT; Vinks, AA; Mizuno, T. Forecasting Fetal Buprenorphine Exposure through Maternal-Fetal Physiologically Based Pharmacokinetic Modeling. Pharmaceutics. 2024; 16(3).

Shimamoto, Y; Fukushima, K; Mizuno, T; Ichikawa, H; Kurosaki, K; Maeda, S; Okuda, M. Model-Informed Vancomycin Dosing Optimization to Address Delayed Renal Maturation in Infants and Young Children with Critical Congenital Heart Disease. Clinical Pharmacology and Therapeutics. 2024; 115(2):239-247.

Paice, K; Girdwood, ST; Pavia, K; Mizuno, T; Kaplan, J. 868: EARLY MEROPENEM CLEARANCE OF CRITICALLY ILL PATIENTS IN A PEDIATRIC INTENSIVE CARE UNIT. Critical Care Medicine. 2024; 52(1):s407-s407.

Sagcal-Gironella, ACP; Merritt, A; Mizuno, T; Dharnidharka, VR; Mcdonald, J; Deguzman, M; Wahezi, D; Goilav, B; Onel, K; Kim, S; Hersh, A; Huang, B; Devarajan, P; Brunner, H. Efficacy and Safety of Pharmacokinetically-Driven Dosing of Mycophenolate Mofetil for the Treatment of Pediatric Proliferative Lupus Nephritis-A Double-Blind Placebo Controlled Clinical Trial (The Pediatric Lupus Nephritis Mycophenolate Mofetil Study). Journal of Clinical Trials. 2024; 14(4).

Cervantes, FC; Mizuno, T; Dong, M; Tang, P; Arbough, T; Vinks, AA; Kaplan, JM; Tang Girdwood, SC. Ceftriaxone Pharmacokinetics and Pharmacodynamics in 2 Pediatric Patients on Extracorporeal Membrane Oxygenation Therapy. Therapeutic Drug Monitoring. 2023; 45(6):832-836.

Taylor, ZL; Poweleit, EA; Paice, K; Somers, KM; Pavia, K; Vinks, AA; Punt, N; Mizuno, T; Girdwood, ST. Tutorial on model selection and validation of model input into precision dosing software for model-informed precision dosing. CPT: Pharmacometrics and Systems Pharmacology. 2023; 12(12):1827-1845.

Poweleit, EA; Taylor, ZL; Mizuno, T; Vaughn, SE; Desta, Z; Strawn, JR; Ramsey, LB. Escitalopram and Sertraline Population Pharmacokinetic Analysis in Pediatric Patients. Clinical Pharmacokinetics. 2023; 62(11):1621-1637.

Alghamdi, A; Seay, S; Hooper, DK; Varnell, CD; Darland, L; Mizuno, T; Lazear, D; Ramsey, LB. Tacrolimus pharmacokinetics are influenced by CYP3A5, age, and concomitant fluconazole in pediatric kidney transplant patients. Clinical and Translational Science. 2023; 16(10):1768-1778.

Pavia, K; Hambrick, HR; Paice, K; Tang, P; Punt, N; Kaplan, J; Goldstein, SL; Vinks, AA; Mizuno, T; Tang Girdwood, S. Cefepime pharmacokinetics in critically ill children and young adults undergoing continuous kidney replacement therapy. Journal of Antimicrobial Chemotherapy. 2023; 78(9):2140-2147.

Colman, RJ; Samuels, A; Mizuno, T; Punt, N; Vinks, AA; Minar, P. Model-informed Precision Dosing for Biologics Is Now Available at the Bedside for Patients With Inflammatory Bowel Disease. Inflammatory Bowel Diseases. 2023; 29(8):1342-1346.

Miyagawa, B; Lazear, D; Hooper, DK; Vinks, AA; Mizuno, T. Model-Informed Estimation of Acutely Decreased Tacrolimus Clearance and Subsequent Dose Individualization in a Pediatric Renal Transplant Patient With Posterior Reversible Encephalopathy Syndrome. Therapeutic Drug Monitoring. 2023; 45(3):376-382.

Whaley, KG; Xiong, Y; Karns, R; Hyams, JS; Kugathasan, S; Boyle, BM; Walters, TD; Kelsen, J; Leleiko, N; Shapiro, J; D'haens, GR; Denson, LA; Vinks, AA; Rosen, MJ. Multicenter Cohort Study of Infliximab Pharmacokinetics and Therapy Response in Pediatric Acute Severe Ulcerative Colitis. Clinical Gastroenterology and Hepatology. 2023; 21(5):1338-1347.

Samuels, A; Punt, N; Mizuno, T; Vinks, AA; Minar, PP. 347 DISEASE PROGRESSION PHARMACOKINETIC MODELING IMPROVES THE ACCURACY OF EARLY INFLIXIMAB CONCENTRATION TARGETS. Gastroenterology. 2023; 164(6):s-59.

Rosen, MJ; Rabizadeh, S; Panetta, JC; Mizuno, T; Vinks, AA; Whaley, KG; Hyams, JS; Kugathasan, S; Boyle, BM; Walters, TD; Kelsen, JR; Leleiko, NS; Shapiro, JM; Dervieux, T. 714 INFLIXIMAB CLEARANCE IN RELATION TO DISEASE ACTIVITY DURING INDUCTION AND MAINTENANCE THERAPY OF ACUTE SEVERE AND AMBULATORY PEDIATRIC ULCERATIVE COLITIS. Gastroenterology. 2023; 164(6):s-150.

Poweleit, EA; Vinks, AA; Mizuno, T. Artificial Intelligence and Machine Learning Approaches to Facilitate Therapeutic Drug Management and Model-Informed Precision Dosing. Therapeutic Drug Monitoring. 2023; 45(2):143-150.

Colman, RJ; Mizuno, T; Fukushima, K; Haslam, DB; Hyams, JS; Boyle, B; Noe, JD; D'haens, GR; Van Limbergen, J; Chun, K; Yang, J; Denson, LA; Ollberding, NJ; Vinks, AA; Minar, P. Real world population pharmacokinetic study in children and young adults with inflammatory bowel disease discovers novel blood and stool microbial predictors of vedolizumab clearance. Alimentary Pharmacology and Therapeutics. 2023; 57(5):524-539.

Pavia, K; Girdwood, ST; Paice, K; Jones, R; Curry, C; Stoneman, E; Yunger, T; Gamel, N; Gibson, A; Dong, M; Tang, P; Mizuno, T; Vinks, A; Kaplan, J. 610: RENAL IMPAIRMENT IS ASSOCIATED WITH HIGH CEFEPIME CONCENTRATIONS IN CRITICALLY ILL CHILDREN. Critical Care Medicine. 2023; 51(1):294-294.

Paice, K; Girdwood, ST; Pavia, K; Mizuno, T; Tang, P; Curry, C; Gibson, A; Jones, R; Stoneman, E; Yunger, T; Dong, M; Vinks, A; Kaplan, J. 38: CRITICALLY ILL CHILDREN WITH SEVERE SEPSIS OFTEN HAVE SUB-TARGET MEROPENEM LEVELS EARLY IN THERAPY. Critical Care Medicine. 2023; 51(1):19-19.

Caldwell, J; Lazear, D; Miyagawa, B; Mizuno, T; Quinn, CT; Stone, H; Hooper, DK; Varnell, CD. Pharmacokinetic-Guided Dosing to Maintain Therapeutic Tacrolimus Levels During Post-Kidney Transplant Erythrocytapheresis in a Patient With Sickle Cell Anemia. Journal of the American Society of Nephrology. 2022; 33(11S):840-840.

Van Hoogdalem, MW; Wexelblatt, SL; Akinbi, HT; Vinks, AA; Mizuno, T. A review of pregnancy-induced changes in opioid pharmacokinetics, placental transfer, and fetal exposure: Towards fetomaternal physiologically-based pharmacokinetic modeling to improve the treatment of neonatal opioid withdrawal syndrome. Pharmacology and Therapeutics. 2022; 234:108045.

Colman, RJ; Xiong, Y; Mizuno, T; Hyams, JS; Noe, JD; Boyle, B; D'haens, GR; Van Limbergen, J; Chun, K; Yang, J; Rosen, MJ; Denson, LA; Vinks, AA; Minar, P. Antibodies-to-infliximab accelerate clearance while dose intensification reverses immunogenicity and recaptures clinical response in paediatric Crohn's disease. Alimentary Pharmacology and Therapeutics. 2022; 55(5):593-603.

Colman, R; Mizuno, T; Hyams, J; Noe, J; Boyle, B; Denson, L; Vinks, A; Minar, P. REAL-WORLD VEDOLIZUMAB PHARMACOKINETIC STUDY IN CHILDREN IDENTIFIES TWO NOVEL BIOMARKERS OF DRUG CLEARANCE. Gastroenterology. 2022; 162(3):s100.

Samuels, A; Punt, N; Reifenberg, J; Mizuno, T; Colman, R; Menke, F; Vogt, A; Vinks, A; Minar, P. PREDICTIVE PERFORMANCE OF DIFFERENT POPULATION PHARMACOKINETIC MODELS IN A REAL-WORLD COHORT OF CROHN’S DISEASE PATIENTS. Gastroenterology. 2022; 162(3):s99-s100.

Minar, P; Samuels, A; Mizuno, T; Menke, F; Vogt, A; Punt, N; Vinks, A. BIOLOGIC PRECISION DOSING IS NOW AVAILABLE AT THE BEDSIDE FOR CHILDREN AND ADULTS WITH INFLAMMATORY BOWEL DISEASE RECEIVING INFLIXIMAB. Gastroenterology. 2022; 162(3):s98-s99.

Van Hoogdalem, MW; Johnson, TN; Mcphail, BT; Kamatkar, S; Wexelblatt, SL; Ward, LP; Christians, U; Akinbi, HT; Vinks, AA; Mizuno, T. Physiologically-Based Pharmacokinetic Modeling to Investigate the Effect of Maturation on Buprenorphine Pharmacokinetics in Newborns with Neonatal Opioid Withdrawal Syndrome. Clinical Pharmacology and Therapeutics. 2022; 111(2):496-508.

Mizuno, T; Dong, M; Taylor, ZL; Ramsey, LB; Vinks, AA. Clinical implementation of pharmacogenetics and model-informed precision dosing to improve patient care. British Journal of Clinical Pharmacology. 2022; 88(4):1418-1426.

Colman, R; Mizuno, T; Hyams, J; Noe, J; Boyle, B; Denson, L; Vinks, A; Minar, P. REAL-WORLD VEDOLIZUMAB PHARMACOKINETIC STUDY IN CHILDREN IDENTIFIES TWO NOVEL BIOMARKERS OF DRUG CLEARANCE. Inflammatory Bowel Diseases. 2022; 28(Supplement_1):s100-s100.

Samuels, A; Punt, N; Reifenberg, J; Mizuno, T; Colman, R; Menke, F; Vogt, A; Vinks, A; Minar, P. PREDICTIVE PERFORMANCE OF DIFFERENT POPULATION PHARMACOKINETIC MODELS IN A REAL-WORLD COHORT OF CROHN’S DISEASE PATIENTS. Inflammatory Bowel Diseases. 2022; 28(Supplement_1):s99-s100.

Minar, P; Samuels, A; Mizuno, T; Menke, F; Vogt, A; Punt, N; Vinks, A. BIOLOGIC PRECISION DOSING IS NOW AVAILABLE AT THE BEDSIDE FOR CHILDREN AND ADULTS WITH INFLAMMATORY BOWEL DISEASE RECEIVING INFLIXIMAB. Inflammatory Bowel Diseases. 2022; 28(Supplement_1):s98-s99.

Hirabatake, M; Mizuno, T; Kato, H; Hashida, T. Everolimus pharmacokinetics and exposure-response relationship in Japanese patients with advanced breast cancer. Frontiers in Pharmacology. 2022; 13:984002.