Tang Girdwood Lab

Publications

Pavia, K; Girdwood, ST; Kaplan, J. Complexity in assessing acute kidney injury and cefepime exposure in critically ill patients. Pediatric Nephrology. 2025; 40:2101-2102.

Morales Junior, R; Hambrick, HR; Mizuno, T; Pavia, KE; Paice, KM; Tang, P; Schuler, E; Krallman, KA; Johnson, L; Collins, M; Gibson, A; Curry, C; Kaplan, J; Goldstein, S; Tang Girdwood, S. Population Pharmacokinetics of Cefepime in Critically Ill Children and Young Adults: Model Development and External Validation for Monte Carlo Simulations and Model-Informed Precision Dosing. Clinical Pharmacokinetics. 2025; 64:553-564.

Tan, WR; Irie, K; Mcintire, C; Torres, JL; Jones, R; Gibson, A; Mizuno, T; Girdwood, ST. Model-informed dose optimization for prophylactic piperacillin-tazobactam in perioperative pediatric critically ill patients. Editor, Doernberg S. Antimicrobial Agents and Chemotherapy. 2025; 69:e0122724.

Pavia, K; Girdwood, ST; Paice, K; Dong, M; Mizuno, T; Tang, P; Mangeot, C; Vinks, AA; Kaplan, J. Acute kidney injury is associated with abnormal cefepime exposure among critically ill children and young adults. Pediatric Nephrology. 2025; 40:513-521.

Cavallari, LH; Hicks, JK; Patel, JN; Elchynski, AL; Smith, DM; Bargal, SA; Fleck, A; Aquilante, CL; Killam, SR; Lemke, L; Tuteja, S; Woodahl, EL; Yuan, LC; Lee, CR. The Pharmacogenomics Global Research Network Implementation Working Group: global collaboration to advance pharmacogenetic implementation. Pharmacogenetics and Genomics. 2025; 35:1-11.

Hambrick, HR; Punt, N; Pavia, K; Mizuno, T; Goldstein, SL; Tang Girdwood, S. Monte Carlo simulations of cefepime in children receiving continuous kidney replacement therapy support continuous infusions for target attainment. Journal of Intensive Care. 2024; 12:38.

Paice, K; Tang Girdwood, S; Mizuno, T; Pavia, K; Punt, N; Tang, P; Dong, M; Curry, C; Jones, R; Gibson, A; Vinks, AA; Kaplan, J. Pharmacokinetic Factors Associated With Early Meropenem Target Attainment in Pediatric Severe Sepsis. Pediatric Critical Care Medicine. 2024; 25:1103-1116.

Morales Junior, R; Hosawi, A; Tang Girdwood, S; Dong, M; Juodinis, V; Romano, P; Ebner, P; Duarte, N; de Souza, D; Santos, S. Optimizing Piperacillin Dosing in Pediatric Liver Transplant Recipients: A Case Series. Pediatric Transplantation. 2024; 28:e14860.

Junior, RM; Mizuno, T; Paice, KM; Pavia, KE; Rhodes Hambrick, H; Tang, P; Jones, R; Gibson, A; Stoneman, E; Curry, C; Kaplan, J; Girdwood, ST. Identifying optimal dosing strategies for meropenem in the paediatric intensive care unit through modelling and simulation. Journal of Antimicrobial Chemotherapy. 2024; 79:2668-2677.

Morales, R; Mizuno, T; Paice, KM; Hambrick, HR; Punt, N; Tang Girdwood, S. Impact of fluid balance on beta-lactam antibiotics target attainment: Insights from a simulation-based meropenem study. International Journal of Antimicrobial Agents. 2024; 64:107267.

Morales Junior, R; Amajor, V; Paice, K; Kyler, KE; Hambrick, HR; Pavia, KE; Haynes, AS; Gooden, F; Pais, GM; Downes, KJ; Ramsey, LB; Wagner, J; Tang Girdwood, S. From Dose to Exposure: Shifting the Paradigm of Pediatric Clinical Pharmacology Research and Education. Clinical Pharmacology and Therapeutics. 2024; 116:515-517.

Hambrick, HR; Fei, L; Pavia, K; Kaplan, J; Mizuno, T; Tang, P; Schuler, E; Benoit, S; Girdwood, ST. Cystatin C Outperforms Creatinine in Predicting Cefepime Clearance in Pediatric Stem Cell Transplant Recipients. Transplantation and Cellular Therapy. 2024; 30:614.e1-614.e11.

Hambrick, HR; Cervantes, F; Dong, M; Tang, P; Arbough, T; Vinks, AA; Mizuno, T; Goldstein, SL; Kaplan, J; Girdwood, ST. Ceftriaxone Pharmacokinetics and Pharmacodynamic Target Attainment for Three Pediatric Patients Receiving Continuous Kidney Replacement Therapy. Journal of Pediatric Pharmacology and Therapeutics. 2024; 29:180-187.

McIntire, C; Luna Torres, J; Tang, P; Vinks, AA; Kaplan, J; Tang Girdwood, S. Piperacillin pharmacokinetics and pharmacodynamics in paediatric patients who received high frequency intra-operative piperacillin/tazobactam dosing. International Journal of Antimicrobial Agents. 2024; 63:107079.

Tang Girdwood, S; Hall, M; Antoon, JW; Kyler, KE; Williams, DJ; Shah, SS; Orth, LE; Goldman, J; Feinstein, JA; Ramsey, LB. Opportunities for Pharmacogenetic Testing to Guide Dosing of Medications in Youths With Medicaid. JAMA Network Open. 2024; 7:e2355707.

Hambrick, HR; Pavia, K; Tang Girdwood, S; Lazear, D; Taylor, JM; Benoit, S. Cefepime-Associated Neurotoxicity in a Pediatric Patient With Stage V Chronic Kidney Disease. Journal of Pharmacy Practice. 2024; 37:243-247.

Kyler, KE; Hall, M; Antoon, JW; Goldman, J; Shah, SS; Girdwood, ST; Williams, DJ; Feinstein, JA. Major Drug-Drug Interaction Exposure Among Medicaid-Insured Children in the Outpatient Setting. Pediatrics. 2024; 153:e2023063506.

Paice, K; Tang Girdwood, S; Pavia, K; Mizuno, T; Kaplan, J. 868: EARLY MEROPENEM CLEARANCE OF CRITICALLY ILL PATIENTS IN A PEDIATRIC INTENSIVE CARE UNIT. Critical Care Medicine. 2024; 52:s407.

Miller, E; Girdwood, ST; Shah, A; Anyigbo, C; Lanphier, E. Professionalism or prejudice? Modelling roles, risking microaggressions. Journal of Medical Ethics. 2023; 49:822-823.

Taylor, ZL; Poweleit, EA; Paice, K; Somers, KM; Pavia, K; Vinks, AA; Punt, N; Mizuno, T; Girdwood, ST. Tutorial on model selection and validation of model input into precision dosing software for model-informed precision dosing. CPT: Pharmacometrics and Systems Pharmacology. 2023; 12:1827-1845.

Cervantes, FC; Mizuno, T; Dong, M; Tang, P; Arbough, T; Vinks, AA; Kaplan, JM; Girdwood, SC T. Ceftriaxone Pharmacokinetics and Pharmacodynamics in 2 Pediatric Patients on Extracorporeal Membrane Oxygenation Therapy. Therapeutic Drug Monitoring. 2023; 45:832-836.

Ramsey, LB; Prows, CA; Tang Girdwood, S; Van Driest, S. Current Practices in Pharmacogenomics. Pediatric Clinics of North America. 2023; 70:995-1011.

Pavia, K; Hambrick, HR; Paice, K; Tang, P; Punt, N; Kaplan, J; Goldstein, SL; Vinks, AA; Mizuno, T; Tang Girdwood, S. Cefepime pharmacokinetics in critically ill children and young adults undergoing continuous kidney replacement therapy. Journal of Antimicrobial Chemotherapy. 2023; 78:2140-2147.

Hambrick, HR; Tang Girdwood, S. The importance of being generic: Avoiding brand names for safety and clarity. Journal of hospital medicine (Online). 2023; 18:870-871.

Morrison, JM; Cotter, JM; Jenkins, AM; Kyler, KE; Girdwood, SC T. Fostering sustainable interinstitutional peer mentorship groups to support professional goals in hospital medicine. Journal of hospital medicine (Online). 2023; 18:761-764.

Kyler, KE; Hall, M; Antoon, JW; Goldman, J; Grijalva, CG; Shah, SS; Tang Girdwood, S; Williams, DJ; Feinstein, JA. Polypharmacy among medicaid-insured children with and without documented obesity. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 2023; 43:588-595.

Ramsey, LB; Prows, CA; Chidambaran, V; Sadhasivam, S; Quinn, CT; Teusink-Cross, A; Tang Girdwood, S; Dawson, DB; Vinks, AA; Glauser, TA. Implementation of CYP2D6-guided opioid therapy at Cincinnati Children's Hospital Medical Center. American Journal of Health-System Pharmacy. 2023; 80:852-859.

Tang Girdwood, S; Tang, P; Fenchel, M; Dong, M; Stoneman, E; Jones, R; Ostermeier, A; Curry, C; Forton, M; Hail, T; Mullaney, R; Diseroad, E; Punt, N; Kaplan, J; Vinks, AA. Pharmacokinetic parameters over time during sepsis and the association of target attainment and outcomes in critically ill children and young adults receiving ceftriaxone. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 2023; 43:609-621.

Antoon, JW; Hall, M; Feinstein, JA; Kyler, KE; Shah, SS; Girdwood, ST; Goldman, JL; Grijalva, CG; Williams, DJ. Guideline-Concordant Antiviral Treatment in Children at High Risk for Influenza Complications. Clinical Infectious Diseases. 2023; 76:e1040-e1046.

Girdwood, ST; Hasson, D; Caldwell, JT; Slagle, C; Dong, S; Fei, L; Tang, P; Vinks, AA; Kaplan, J; Goldstein, SL. Relationship between piperacillin concentrations, clinical factors and piperacillin/tazobactam-associated acute kidney injury. Journal of Antimicrobial Chemotherapy. 2023; 78:478-487.

Pavia, K; Girdwood, ST; Paice, K; Jones, R; Curry, C; Stoneman, E; Yunger, T; Gamel, N; Gibson, A; Dong, M; Tang, P; Mizuno, T; Vinks, A; Kaplan, J. 610: RENAL IMPAIRMENT IS ASSOCIATED WITH HIGH CEFEPIME CONCENTRATIONS IN CRITICALLY ILL CHILDREN. Critical Care Medicine. 2023; 51:294.

Paice, K; Girdwood, ST; Pavia, K; Mizuno, T; Tang, P; Curry, C; Gibson, A; Jones, R; Stoneman, E; Yunger, T; Dong, M; Vinks, A; Kaplan, J. 38: CRITICALLY ILL CHILDREN WITH SEVERE SEPSIS OFTEN HAVE SUB-TARGET MEROPENEM LEVELS EARLY IN THERAPY. Critical Care Medicine. 2023; 51:19.

Tang Girdwood, S; Pavia, K; Paice, K; Hambrick, HR; Kaplan, J; Vinks, AA. β-lactam precision dosing in critically ill children: Current state and knowledge gaps. Frontiers in Pharmacology. 2022; 13:1044683.

Tang Girdwood, SC; Rossow, KM; Van Driest, SL; Ramsey, LB. Perspectives from the Society for Pediatric Research: pharmacogenetics for pediatricians. Pediatric Research. 2022; 91:529-538.

Girdwood, ST; Dong, M; Tang, P; Stoneman, E; Jones, R; Yunger, T; Ostermeier, A; Curry, C; Forton, M; Hail, T; Mullaney, R; Lahni, P; Punt, N; Kaplan, J; Vinks, AA. Population Pharmacokinetic Modeling of Total and Free Ceftriaxone in Critically Ill Children and Young Adults and Monte Carlo Simulations Support Twice Daily Dosing for Target Attainment. Antimicrobial Agents and Chemotherapy. 2022; 66:e0142721.

Murphy, ME; Tang Girdwood, S; Goldman, JL; Scheetz, MH; Downes, KJ. Precision dosing of vancomycin: in defence of AUC-guided therapy in children. Journal of Antimicrobial Chemotherapy. 2021; 76:2494-2497.

Tang Girdwood, SC; Tang, PH; Murphy, ME; Chamberlain, AR; Benken, LA; Jones, RL; Stoneman, EM; Kaplan, JM; Vinks, AA. Demonstrating Feasibility of an Opportunistic Sampling Approach for Pharmacokinetic Studies of β-Lactam Antibiotics in Critically Ill Children. The Journal of Clinical Pharmacology. 2021; 61:565-573.

Cotter, JM; Hall, M; Girdwood, ST; Stephens, JR; Markham, JL; Gay, JC; Shah, SS. Opportunities for Stewardship in the Transition From Intravenous to Enteral Antibiotics in Hospitalized Pediatric Patients. Journal of hospital medicine (Online). 2021; 16:70-76.

Girdwood, ST; Kaplan, J; Vinks, AA. Methodologic Progress Note: Opportunistic Sampling for Pharmacology Studies in Hospitalized Children. Journal of hospital medicine (Online). 2021; 16:35-37.